Paranoid Disorders Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D010259
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Genes

181 genes/proteins associated with the disease Paranoid Disorders from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 2.88009
MANEA mannosidase, endo-alpha 2.88009
DNAH8 dynein, axonemal, heavy chain 8 2.88009
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 2.88009
TYK2 tyrosine kinase 2 2.88009
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 2.88009
ICE2 interactor of little elongation complex ELL subunit 2 2.88009
AKR1C4 aldo-keto reductase family 1, member C4 2.88009
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 2.27972
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 2.25165
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 2.24839
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 2.23968
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 2.23454
PRL prolactin 2.16476
DRD2 dopamine receptor D2 2.15914
BDNF brain-derived neurotrophic factor 2.14358
FOS FBJ murine osteosarcoma viral oncogene homolog 2.1062
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 2.0951
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.00343
CAT catalase 1.94889
PENK proenkephalin 1.94217
BAX BCL2-associated X protein 1.93844
NPY neuropeptide Y 1.90853
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.87659
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 1.86375
MAPK1 mitogen-activated protein kinase 1 1.82429
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.81994
CREB1 cAMP responsive element binding protein 1 1.78454
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 1.77024
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 1.76771
TAC1 tachykinin, precursor 1 1.76636
FNDC4 fibronectin type III domain containing 4 1.76462
EGR1 early growth response 1 1.76111
NUPR1 nuclear protein, transcriptional regulator, 1 1.73758
MAPK3 mitogen-activated protein kinase 3 1.72178
C10ORF10 chromosome 10 open reading frame 10 1.71871
BCL2 B-cell CLL/lymphoma 2 1.71482
TNF tumor necrosis factor 1.71296
PDYN prodynorphin 1.70326
TH tyrosine hydroxylase 1.68718
CRH corticotropin releasing hormone 1.67526
DRD3 dopamine receptor D3 1.66835
HRH1 histamine receptor H1 1.66339
DRD1 dopamine receptor D1 1.65753
SOD1 superoxide dismutase 1, soluble 1.65292
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 1.64595
TAGLN transgelin 1.64348
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.63496
ARC activity-regulated cytoskeleton-associated protein 1.63138
NR0B2 nuclear receptor subfamily 0, group B, member 2 1.62713
MAPK8 mitogen-activated protein kinase 8 1.61713
INHBE inhibin, beta E 1.61014
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 1.61014
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 1.60897
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 1.60664
WIPI1 WD repeat domain, phosphoinositide interacting 1 1.60617
GSK3B glycogen synthase kinase 3 beta 1.60594
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 1.60012
HOMER1 homer scaffolding protein 1 1.58279
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.58113
JUNB jun B proto-oncogene 1.55402
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.54111
HPN hepsin 1.53965
FOSB FBJ murine osteosarcoma viral oncogene homolog B 1.5382
EGR2 early growth response 2 1.52642
MAP2 microtubule-associated protein 2 1.52439
GFAP glial fibrillary acidic protein 1.50398
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 1.50373
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.48428
COMT catechol-O-methyltransferase 1.48376
FABP1 fatty acid binding protein 1, liver 1.48196
JUN jun proto-oncogene 1.4633
AP1S1 adaptor-related protein complex 1, sigma 1 subunit 1.46225
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 1.45063
IL6 interleukin 6 1.44708
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 1.44544
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 1.4351
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.42804
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.42454
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.42374
RGS4 regulator of G-protein signaling 4 1.41829
AVP arginine vasopressin 1.41829
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.40815
CDK5 cyclin-dependent kinase 5 1.40595
GSTP1 glutathione S-transferase pi 1 1.40204
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 1.3931
NR4A1 nuclear receptor subfamily 4, group A, member 1 1.39002
MAOB monoamine oxidase B 1.38863
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 1.3878
GRM1 glutamate receptor, metabotropic 1 1.37902
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 1.37532
DRD4 dopamine receptor D4 1.37475
MAPK14 mitogen-activated protein kinase 14 1.36677
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.36504
GRIA2 glutamate receptor, ionotropic, AMPA 2 1.35821
OPRM1 opioid receptor, mu 1 1.34897
INS insulin 1.34782
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 1.34664
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.34198
FAS Fas cell surface death receptor 1.34082
FGF2 fibroblast growth factor 2 (basic) 1.33612
SREBF2 sterol regulatory element binding transcription factor 2 1.32756
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.32577
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.31119
VEGFA vascular endothelial growth factor A 1.29626
CTSK cathepsin K 1.29287
CES2 carboxylesterase 2 1.28765
CXCL8 chemokine (C-X-C motif) ligand 8 1.28765
GSK3A glycogen synthase kinase 3 alpha 1.27409
RGS2 regulator of G-protein signaling 2 1.27378
PRKCB protein kinase C, beta 1.26947
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 1.26421
FOSL2 FOS-like antigen 2 1.26113
NGF nerve growth factor (beta polypeptide) 1.25121
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 1.24401
POMC proopiomelanocortin 1.23743
BCL2L1 BCL2-like 1 1.23042
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 1.22209
SREBF1 sterol regulatory element binding transcription factor 1 1.21791
CREM cAMP responsive element modulator 1.2137
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.21337
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 1.21011
DUSP1 dual specificity phosphatase 1 1.20622
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.199
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 1.19574
GRK6 G protein-coupled receptor kinase 6 1.19412
SOD2 superoxide dismutase 2, mitochondrial 1.19379
FOSL1 FOS-like antigen 1 1.18521
NCAN neurocan 1.17761
TRH thyrotropin-releasing hormone 1.17728
SYP synaptophysin 1.167
IFNG interferon, gamma 1.15695
LDLR low density lipoprotein receptor 1.14816
ELK1 ELK1, member of ETS oncogene family 1.14438
CALCA calcitonin-related polypeptide alpha 1.14336
PKM pyruvate kinase, muscle 1.14268
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2 1.14132
GRIA1 glutamate receptor, ionotropic, AMPA 1 1.13827
SCD stearoyl-CoA desaturase (delta-9-desaturase) 1.12805
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.12391
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 1.12014
SYT5 synaptotagmin V 1.1122
INHA inhibin, alpha 1.11186
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 1.10631
MAOA monoamine oxidase A 1.09998
PARP1 poly (ADP-ribose) polymerase 1 1.09506
CNR1 cannabinoid receptor 1 (brain) 1.09436
SGK1 serum/glucocorticoid regulated kinase 1 1.09262
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 1.09262
RORB RAR-related orphan receptor B 1.08868
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 1.07947
ADORA2A adenosine A2a receptor 1.07696
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 1.0766
DCAF8 DDB1 and CUL4 associated factor 8 1.07518
ARRB2 arrestin, beta 2 1.07411
POR P450 (cytochrome) oxidoreductase 1.07305
ALDOA aldolase A, fructose-bisphosphate 1.07163
GRM5 glutamate receptor, metabotropic 5 1.06261
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled 1.06261
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 1.06188
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 1.05936
CAMK2B calcium/calmodulin-dependent protein kinase II beta 1.059
PPP5C protein phosphatase 5, catalytic subunit 1.05461
ADAM1A ADAM metallopeptidase domain 1A (pseudogene) 1.05237
MBP myelin basic protein 1.052
OXT oxytocin/neurophysin I prepropeptide 1.04978
NR4A2 nuclear receptor subfamily 4, group A, member 2 1.04501
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 1.04051
REN renin 1.03939
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 1.03789
EIF5A eukaryotic translation initiation factor 5A 1.03678
SCG2 secretogranin II 1.03604
GRIK2 glutamate receptor, ionotropic, kainate 2 1.03567
LOX lysyl oxidase 1.03084
S100A9 S100 calcium binding protein A9 1.02858
IL1A interleukin 1, alpha 1.02596
IL1B interleukin 1, beta 1.02225
IL10 interleukin 10 1.01928
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 1.01776
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3 1.01361
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 1.01361