Pancreatic Diseases Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D010182
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Genes

185 genes/proteins associated with the disease Pancreatic Diseases from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
AGER advanced glycosylation end product-specific receptor 2.88009
LEPR leptin receptor 2.88009
POMC proopiomelanocortin 2.88009
HMOX1 heme oxygenase 1 2.88009
ALB albumin 2.88009
SPP1 secreted phosphoprotein 1 2.88009
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.01567
ICAM1 intercellular adhesion molecule 1 1.8928
BAX BCL2-associated X protein 1.84764
TIMP1 TIMP metallopeptidase inhibitor 1 1.80416
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.74501
IGF1 insulin-like growth factor 1 (somatomedin C) 1.73028
TNF tumor necrosis factor 1.72884
BCL2 B-cell CLL/lymphoma 2 1.72884
PPARA peroxisome proliferator-activated receptor alpha 1.72158
CAT catalase 1.70719
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.70491
NOS2 nitric oxide synthase 2, inducible 1.69846
TGFB1 transforming growth factor, beta 1 1.6934
IL6 interleukin 6 1.67569
VEGFA vascular endothelial growth factor A 1.66511
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.62268
PPARG peroxisome proliferator-activated receptor gamma 1.61014
NCF1 neutrophil cytosolic factor 1 1.59101
VCAM1 vascular cell adhesion molecule 1 1.58491
CYCS cytochrome c, somatic 1.57329
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.57186
SOD2 superoxide dismutase 2, mitochondrial 1.56558
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 1.56092
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.55648
FN1 fibronectin 1 1.55255
EDN1 endothelin 1 1.54596
IFNG interferon, gamma 1.53699
INS insulin 1.53651
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.5254
MAPK3 mitogen-activated protein kinase 3 1.52413
NOS3 nitric oxide synthase 3 (endothelial cell) 1.5186
MMP2 matrix metallopeptidase 2 1.51708
NQO1 NAD(P)H dehydrogenase, quinone 1 1.51607
MAPK1 mitogen-activated protein kinase 1 1.51506
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.51004
CYBA cytochrome b-245, alpha polypeptide 1.50498
FASLG Fas ligand (TNF superfamily, member 6) 1.49762
FASN fatty acid synthase 1.4753
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 1.46832
IL1B interleukin 1, beta 1.45777
TP53 tumor protein p53 1.45194
TIMP2 TIMP metallopeptidase inhibitor 2 1.44681
NOX4 NADPH oxidase 4 1.4332
CCL2 chemokine (C-C motif) ligand 2 1.41229
CXCL8 chemokine (C-X-C motif) ligand 8 1.40705
GSTA3 glutathione S-transferase alpha 3 1.40513
GSR glutathione reductase 1.39841
VIM vimentin 1.37958
JUN jun proto-oncogene 1.37874
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.37246
SREBF1 sterol regulatory element binding transcription factor 1 1.37217
ACACA acetyl-CoA carboxylase alpha 1.3699
COL1A1 collagen, type I, alpha 1 1.36876
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.36876
SOD1 superoxide dismutase 1, soluble 1.36304
IL10 interleukin 10 1.35647
LPL lipoprotein lipase 1.35357
HSPB1 heat shock 27kDa protein 1 1.35242
NPY neuropeptide Y 1.35127
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.34635
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.34606
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.34459
ACTA2 actin, alpha 2, smooth muscle, aorta 1.34256
NFE2L2 nuclear factor, erythroid 2-like 2 1.33523
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.32518
CD44 CD44 molecule (Indian blood group) 1.31985
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.31897
FOS FBJ murine osteosarcoma viral oncogene homolog 1.31776
CREB1 cAMP responsive element binding protein 1 1.3036
KDR kinase insert domain receptor 1.28672
BIRC5 baculoviral IAP repeat containing 5 1.27286
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 1.27286
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.26545
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 1.26514
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 1.25929
G6PD glucose-6-phosphate dehydrogenase 1.25713
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.25152
TFRC transferrin receptor 1.24496
TIMP3 TIMP metallopeptidase inhibitor 3 1.24087
APAF1 apoptotic peptidase activating factor 1 1.23743
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 1.2368
GSTM1 glutathione S-transferase mu 1 1.2352
CYBB cytochrome b-245, beta polypeptide 1.23201
VCAN versican 1.22727
NPPB natriuretic peptide B 1.22696
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.22696
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.22371
ESR2 estrogen receptor 2 (ER beta) 1.22371
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.22177
IRS1 insulin receptor substrate 1 1.22016
FAS Fas cell surface death receptor 1.21887
ANXA1 annexin A1 1.21663
CCNE1 cyclin E1 1.21402
IL2 interleukin 2 1.21271
CHAT choline O-acetyltransferase 1.21043
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 1.21011
MAPK9 mitogen-activated protein kinase 9 1.20848
GSTA2 glutathione S-transferase alpha 2 1.20295
MPO myeloperoxidase 1.20163
ENO1 enolase 1, (alpha) 1.19412
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.18981
CPT1A carnitine palmitoyltransferase 1A (liver) 1.18359
IRS2 insulin receptor substrate 2 1.17959
COL4A1 collagen, type IV, alpha 1 1.17959
EGFR epidermal growth factor receptor 1.17926
SCD stearoyl-CoA desaturase (delta-9-desaturase) 1.17034
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.169
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 1.16799
AHR aryl hydrocarbon receptor 1.16666
MAPK8 mitogen-activated protein kinase 8 1.16302
GSK3B glycogen synthase kinase 3 beta 1.15797
GSTA4 glutathione S-transferase alpha 4 1.15627
GCG glucagon 1.1461
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.14404
LDLR low density lipoprotein receptor 1.14166
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 1.13758
BCL2L1 BCL2-like 1 1.13177
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain 1.13109
INSR insulin receptor 1.12737
PTEN phosphatase and tensin homolog 1.11911
PLAT plasminogen activator, tissue 1.11877
BAD BCL2-associated agonist of cell death 1.11775
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.11707
ALAD aminolevulinate dehydratase 1.11571
SOD3 superoxide dismutase 3, extracellular 1.11536
TLR4 toll-like receptor 4 1.11536
APOE apolipoprotein E 1.11536
CROT carnitine O-octanoyltransferase 1.11186
EDNRA endothelin receptor type A 1.10459
PCNA proliferating cell nuclear antigen 1.10069
CALR calreticulin 1.09506
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 1.09226
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 1.0919
LDHA lactate dehydrogenase A 1.09154
MMP9 matrix metallopeptidase 9 1.08833
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 1.08549
THBS1 thrombospondin 1 1.08266
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.07947
UCP3 uncoupling protein 3 (mitochondrial, proton carrier) 1.0766
APOB apolipoprotein B 1.07625
KEAP1 kelch-like ECH-associated protein 1 1.07269
EGF epidermal growth factor 1.06917
ACOX1 acyl-CoA oxidase 1, palmitoyl 1.06297
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) 1.06152
COL3A1 collagen, type III, alpha 1 1.05972
FGF21 fibroblast growth factor 21 1.05936
PPP1R15A protein phosphatase 1, regulatory subunit 15A 1.05936
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 1.05864
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 1.05864
BAK1 BCL2-antagonist/killer 1 1.05498
IL12B interleukin 12B 1.05349
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 1.05089
CKM creatine kinase, muscle 1.05052
IL4 interleukin 4 1.05052
RND3 Rho family GTPase 3 1.04794
MMP13 matrix metallopeptidase 13 1.04538
NRF1 nuclear respiratory factor 1 1.04538
PLIN4 perilipin 4 1.03901
SP1 Sp1 transcription factor 1.03641
CCND1 cyclin D1 1.03567
GPX1 glutathione peroxidase 1 1.03456
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 1.03345
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.03197
CCL5 chemokine (C-C motif) ligand 5 1.03159
SCARB1 scavenger receptor class B, member 1 1.02896
ADIPOR1 adiponectin receptor 1 1.02858
PARP1 poly (ADP-ribose) polymerase 1 1.02596
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 1.02447
PECAM1 platelet/endothelial cell adhesion molecule 1 1.02447
SPHK1 sphingosine kinase 1 1.02225
VEGFC vascular endothelial growth factor C 1.0204
ICAM2 intercellular adhesion molecule 2 1.01928
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.01852
COL1A2 collagen, type I, alpha 2 1.01776
GABPA GA binding protein transcription factor, alpha subunit 60kDa 1.01776
PTHLH parathyroid hormone-like hormone 1.01739
ESR1 estrogen receptor 1 1.01361
PRKCD protein kinase C, delta 1.01361
LDHB lactate dehydrogenase B 1.01025