Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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199 genes differentially expressed following the PNU-0293363-6573 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ACTB | actin, beta |
ALDH18A1 | aldehyde dehydrogenase 18 family, member A1 |
APLP2 | amyloid beta (A4) precursor-like protein 2 |
APP | amyloid beta (A4) precursor protein |
ARF1 | ADP-ribosylation factor 1 |
ATP6V1A | ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A |
BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
C14ORF1 | chromosome 14 open reading frame 1 |
C6ORF62 | chromosome 6 open reading frame 62 |
CA12 | carbonic anhydrase XII |
CAPN7 | calpain 7 |
CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) |
CDC6 | cell division cycle 6 |
CDK16 | cyclin-dependent kinase 16 |
CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
CDYL | chromodomain protein, Y-like |
CHRNA5 | cholinergic receptor, nicotinic, alpha 5 (neuronal) |
CLDN3 | claudin 3 |
CLDND1 | claudin domain containing 1 |
CRK | v-crk avian sarcoma virus CT10 oncogene homolog |
DVL3 | dishevelled segment polarity protein 3 |
EDEM3 | ER degradation enhancer, mannosidase alpha-like 3 |
EIF5A | eukaryotic translation initiation factor 5A |
ENO1 | enolase 1, (alpha) |
FAM179B | family with sequence similarity 179, member B |
FKBP1A | FK506 binding protein 1A, 12kDa |
FLII | flightless I homolog (Drosophila) |
FUS | FUS RNA binding protein |
GAPDH | glyceraldehyde-3-phosphate dehydrogenase |
GART | phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase |
GDI2 | GDP dissociation inhibitor 2 |
GLE1 | GLE1 RNA export mediator |
GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like |
HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 |
HMG20B | high mobility group 20B |
HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) |
HPCAL1 | hippocalcin-like 1 |
HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 |
ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 |
KDELR3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 |
KIAA0125 | KIAA0125 |
KIAA1033 | KIAA1033 |
LAMP1 | lysosomal-associated membrane protein 1 |
LPAR2 | lysophosphatidic acid receptor 2 |
MARK2 | MAP/microtubule affinity-regulating kinase 2 |
MCM4 | minichromosome maintenance complex component 4 |
MED6 | mediator complex subunit 6 |
MPDU1 | mannose-P-dolichol utilization defect 1 |
MSH6 | mutS homolog 6 |
MTMR2 | myotubularin related protein 2 |
MUC1 | mucin 1, cell surface associated |
MXD4 | MAX dimerization protein 4 |
NFYC | nuclear transcription factor Y, gamma |
NNT | nicotinamide nucleotide transhydrogenase |
NUCB1 | nucleobindin 1 |
PDAP1 | PDGFA associated protein 1 |
PGD | phosphogluconate dehydrogenase |
PGRMC1 | progesterone receptor membrane component 1 |
PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
PICALM | phosphatidylinositol binding clathrin assembly protein |
POGK | pogo transposable element with KRAB domain |
POLR2E | polymerase (RNA) II (DNA directed) polypeptide E, 25kDa |
PPIF | peptidylprolyl isomerase F |
PRKDC | protein kinase, DNA-activated, catalytic polypeptide |
PRPF4B | pre-mRNA processing factor 4B |
PRUNE | prune exopolyphosphatase |
PTBP1 | polypyrimidine tract binding protein 1 |
RAB5C | RAB5C, member RAS oncogene family |
RANBP9 | RAN binding protein 9 |
RELA | v-rel avian reticuloendotheliosis viral oncogene homolog A |
RFC3 | replication factor C (activator 1) 3, 38kDa |
RHOBTB3 | Rho-related BTB domain containing 3 |
RRM1 | ribonucleotide reductase M1 |
SDHC | succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa |
SEC23A | Sec23 homolog A (S. cerevisiae) |
SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) |
SGPP1 | sphingosine-1-phosphate phosphatase 1 |
SIGMAR1 | sigma non-opioid intracellular receptor 1 |
SNX3 | sorting nexin 3 |
SPTLC1 | serine palmitoyltransferase, long chain base subunit 1 |
SQLE | squalene epoxidase |
SRPK2 | SRSF protein kinase 2 |
STIP1 | stress-induced phosphoprotein 1 |
TAGLN2 | transgelin 2 |
TANK | TRAF family member-associated NFKB activator |
TIMM44 | translocase of inner mitochondrial membrane 44 homolog (yeast) |
TMED2 | transmembrane emp24 domain trafficking protein 2 |
TMEM183A | transmembrane protein 183A |
TMEM230 | transmembrane protein 230 |
TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
TRRAP | transformation/transcription domain-associated protein |
TSPAN3 | tetraspanin 3 |
VAMP3 | vesicle-associated membrane protein 3 |
WDR1 | WD repeat domain 1 |
WHSC1 | Wolf-Hirschhorn syndrome candidate 1 |
YIPF5 | Yip1 domain family, member 5 |
YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta |
ZFYVE21 | zinc finger, FYVE domain containing 21 |
ZNF654 | zinc finger protein 654 |
ZNF665 | zinc finger protein 665 |
Symbol | Name |
---|---|
A2M | alpha-2-macroglobulin |
APH1A | APH1A gamma secretase subunit |
APOLD1 | apolipoprotein L domain containing 1 |
ARL4A | ADP-ribosylation factor-like 4A |
ARPIN | actin-related protein 2/3 complex inhibitor |
B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
BAX | BCL2-associated X protein |
BCORL1 | BCL6 corepressor-like 1 |
BMS1 | BMS1 ribosome biogenesis factor |
CASP3 | caspase 3, apoptosis-related cysteine peptidase |
CBR3 | carbonyl reductase 3 |
CCDC69 | coiled-coil domain containing 69 |
CDC20 | cell division cycle 20 |
CFAP44 | cilia and flagella associated protein 44 |
CHMP6 | charged multivesicular body protein 6 |
CHMP7 | charged multivesicular body protein 7 |
CORO7 | coronin 7 |
DEPDC1 | DEP domain containing 1 |
DET1 | de-etiolated homolog 1 (Arabidopsis) |
DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
EMID1 | EMI domain containing 1 |
EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
FAAH | fatty acid amide hydrolase |
FBXO46 | F-box protein 46 |
FGL1 | fibrinogen-like 1 |
FLJ22184 | |
FOXC1 | forkhead box C1 |
FPGS | folylpolyglutamate synthase |
FZD2 | frizzled class receptor 2 |
GALE | UDP-galactose-4-epimerase |
GRTP1 | growth hormone regulated TBC protein 1 |
HIRA | histone cell cycle regulator |
HIRIP3 | HIRA interacting protein 3 |
HIST1H1D | histone cluster 1, H1d |
HIST1H4C | histone cluster 1, H4c |
HMHA1 | histocompatibility (minor) HA-1 |
HMOX1 | heme oxygenase 1 |
IRX4 | iroquois homeobox 4 |
KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 |
KCTD7 | potassium channel tetramerization domain containing 7 |
KIAA1324 | KIAA1324 |
KIF20B | kinesin family member 20B |
KIFC1 | kinesin family member C1 |
LAGE3 | L antigen family, member 3 |
LDB1 | LIM domain binding 1 |
LHX6 | LIM homeobox 6 |
LIME1 | Lck interacting transmembrane adaptor 1 |
LINC00115 | long intergenic non-protein coding RNA 115 |
LMNB1 | lamin B1 |
LOC100287590 | uncharacterized LOC100287590 |
LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
LRP3 | low density lipoprotein receptor-related protein 3 |
LY6D | lymphocyte antigen 6 complex, locus D |
MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
METTL1 | methyltransferase like 1 |
MPP6 | membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) |
MYO1F | myosin IF |
NARFL | nuclear prelamin A recognition factor-like |
NDRG4 | NDRG family member 4 |
NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
OGFRL1 | opioid growth factor receptor-like 1 |
PACS1 | phosphofurin acidic cluster sorting protein 1 |
PADI1 | peptidyl arginine deiminase, type I |
PAGR1 | PAXIP1 associated glutamate-rich protein 1 |
PC | pyruvate carboxylase |
PLAC8 | placenta-specific 8 |
PLTP | phospholipid transfer protein |
PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) |
PRR11 | proline rich 11 |
PYCRL | pyrroline-5-carboxylate reductase-like |
RBM4B | RNA binding motif protein 4B |
RFPL3 | ret finger protein-like 3 |
RNF126P1 | ring finger protein 126 pseudogene 1 |
S100A2 | S100 calcium binding protein A2 |
SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
SLC39A7 | solute carrier family 39 (zinc transporter), member 7 |
SNHG3 | small nucleolar RNA host gene 3 |
SSBP3 | single stranded DNA binding protein 3 |
SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) |
SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
TBX19 | T-box 19 |
THNSL2 | threonine synthase-like 2 (S. cerevisiae) |
TMEM121 | transmembrane protein 121 |
TMEM158 | transmembrane protein 158 (gene/pseudogene) |
TNFRSF11A | tumor necrosis factor receptor superfamily, member 11a, NFKB activator |
TUBG2 | tubulin, gamma 2 |
TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
UBTD1 | ubiquitin domain containing 1 |
USP20 | ubiquitin specific peptidase 20 |
VIPR1 | vasoactive intestinal peptide receptor 1 |
VSIG10 | V-set and immunoglobulin domain containing 10 |
ZBTB48 | zinc finger and BTB domain containing 48 |
ZNF16 | zinc finger protein 16 |
ZNF211 | zinc finger protein 211 |
ZNF324 | zinc finger protein 324 |
ZNF574 | zinc finger protein 574 |