PNU-0251126-7390 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools


198 genes differentially expressed following the PNU-0251126-7390 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADRBK1 adrenergic, beta, receptor kinase 1
ALDOB aldolase B, fructose-bisphosphate
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARL15 ADP-ribosylation factor-like 15
ARNT aryl hydrocarbon receptor nuclear translocator
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATN1 atrophin 1
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
AXIN1 axin 1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BET1L Bet1 golgi vesicular membrane trafficking protein-like
BTG2 BTG family, member 2
CASP1 caspase 1, apoptosis-related cysteine peptidase
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CES2 carboxylesterase 2
CISH cytokine inducible SH2-containing protein
CLDN11 claudin 11
CPN2 carboxypeptidase N, polypeptide 2
CST4 cystatin S
DAGLA diacylglycerol lipase, alpha
DCTN1 dynactin 1
DENND2A DENN/MADD domain containing 2A
DGKA diacylglycerol kinase, alpha 80kDa
ECE1 endothelin converting enzyme 1
EGF epidermal growth factor
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ETV1 ets variant 1
EVI5 ecotropic viral integration site 5
F11R F11 receptor
FAM69A family with sequence similarity 69, member A
FASTKD2 FAST kinase domains 2
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FGFR2 fibroblast growth factor receptor 2
FKBP8 FK506 binding protein 8, 38kDa
FRS2 fibroblast growth factor receptor substrate 2
GATA2 GATA binding protein 2
GLP1R glucagon-like peptide 1 receptor
GMIP GEM interacting protein
GREM1 gremlin 1, DAN family BMP antagonist
GSTTP1 glutathione S-transferase theta pseudogene 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IGLJ3 immunoglobulin lambda joining 3
IL17RA interleukin 17 receptor A
IL6 interleukin 6
IRS2 insulin receptor substrate 2
LMNA lamin A/C
LOXL3 lysyl oxidase-like 3
LPAR4 lysophosphatidic acid receptor 4
LRRK1 leucine-rich repeat kinase 1
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MMP13 matrix metallopeptidase 13
MTRF1L mitochondrial translational release factor 1-like
MTSS1L metastasis suppressor 1-like
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NF2 neurofibromin 2 (merlin)
NR4A2 nuclear receptor subfamily 4, group A, member 2
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PASK PAS domain containing serine/threonine kinase
PBOV1 prostate and breast cancer overexpressed 1
PDE12 phosphodiesterase 12
PELO pelota homolog (Drosophila)
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PPARA peroxisome proliferator-activated receptor alpha
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PSKH1 protein serine kinase H1
PVT1 Pvt1 oncogene (non-protein coding)
RARG retinoic acid receptor, gamma
REEP1 receptor accessory protein 1
RGS10 regulator of G-protein signaling 10
RNF122 ring finger protein 122
SARS2 seryl-tRNA synthetase 2, mitochondrial
SBNO1 strawberry notch homolog 1 (Drosophila)
SCN10A sodium channel, voltage gated, type X alpha subunit
SDC3 syndecan 3
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SFRP1 secreted frizzled-related protein 1
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SND1-IT1 SND1 intronic transcript 1
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SYNGR1 synaptogyrin 1
TAZ tafazzin
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TRAIP TRAF interacting protein
TRAPPC13 trafficking protein particle complex 13
TRIM14 tripartite motif containing 14
UBE3B ubiquitin protein ligase E3B
VIPR2 vasoactive intestinal peptide receptor 2
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZC3H12A zinc finger CCCH-type containing 12A
ZNF358 zinc finger protein 358
ZNF701 zinc finger protein 701

decreased expression

Symbol Name
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ABHD17B abhydrolase domain containing 17B
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ADGRG2 adhesion G protein-coupled receptor G2
AFAP1 actin filament associated protein 1
ANKRD40 ankyrin repeat domain 40
AP3M2 adaptor-related protein complex 3, mu 2 subunit
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ASB13 ankyrin repeat and SOCS box containing 13
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATG2B autophagy related 2B
BAG4 BCL2-associated athanogene 4
C16ORF59 chromosome 16 open reading frame 59
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CCDC68 coiled-coil domain containing 68
CD70 CD70 molecule
CDH3 cadherin 3, type 1, P-cadherin (placental)
CDH7 cadherin 7, type 2
CDON cell adhesion associated, oncogene regulated
CENPO centromere protein O
CHM choroideremia (Rab escort protein 1)
CLEC16A C-type lectin domain family 16, member A
CLEC2B C-type lectin domain family 2, member B
CPEB1 cytoplasmic polyadenylation element binding protein 1
CTSO cathepsin O
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
EDC3 enhancer of mRNA decapping 3
ELAVL2 ELAV like neuron-specific RNA binding protein 2
EN2 engrailed homeobox 2
EPPK1 epiplakin 1
ERN2 endoplasmic reticulum to nucleus signaling 2
EXOC3 exocyst complex component 3
FAM53B family with sequence similarity 53, member B
FGD1 FYVE, RhoGEF and PH domain containing 1
FGD6 FYVE, RhoGEF and PH domain containing 6
FOXC1 forkhead box C1
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GALK1 galactokinase 1
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HILPDA hypoxia inducible lipid droplet-associated
HIST1H2BJ histone cluster 1, H2bj
HIST1H3A histone cluster 1, H3a
HOXC10 homeobox C10
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IL7R interleukin 7 receptor
IPO8 importin 8
KIAA0513 KIAA0513
KLHL3 kelch-like family member 3
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LY6G5C lymphocyte antigen 6 complex, locus G5C
MANBA mannosidase, beta A, lysosomal
MFSD10 major facilitator superfamily domain containing 10
MXD3 MAX dimerization protein 3
NLK nemo-like kinase
NPR3 natriuretic peptide receptor 3
NUBPL nucleotide binding protein-like
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PHKG2 phosphorylase kinase, gamma 2 (testis)
PLAC8 placenta-specific 8
PRR7 proline rich 7 (synaptic)
PVRL3 poliovirus receptor-related 3
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RIN1 Ras and Rab interactor 1
RNF25 ring finger protein 25
SCAMP5 secretory carrier membrane protein 5
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3BGR SH3 domain binding glutamate-rich protein
SHPK sedoheptulokinase
SLC12A9 solute carrier family 12, member 9
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC35F6 solute carrier family 35, member F6
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SMG9 SMG9 nonsense mediated mRNA decay factor
SMIM8 small integral membrane protein 8
SPRYD7 SPRY domain containing 7
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STARD5 StAR-related lipid transfer (START) domain containing 5
SYNPO synaptopodin
SYTL2 synaptotagmin-like 2
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TH tyrosine hydroxylase
TMEM132A transmembrane protein 132A
TMEM2 transmembrane protein 2
TMEM209 transmembrane protein 209
TMEM212 transmembrane protein 212
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TSC22D4 TSC22 domain family, member 4
TUBA3C tubulin, alpha 3c
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
VWA1 von Willebrand factor A domain containing 1
WDR33 WD repeat domain 33
ZNF215 zinc finger protein 215
ZNF35 zinc finger protein 35
ZNF408 zinc finger protein 408
ZNF480 zinc finger protein 480
ZNF671 zinc finger protein 671
ZNF84 zinc finger protein 84