PNU-0251126-3692 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the PNU-0251126-3692 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADCK2 aarF domain containing kinase 2
AICDA activation-induced cytidine deaminase
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ALOXE3 arachidonate lipoxygenase 3
ARID4B AT rich interactive domain 4B (RBP1-like)
ARMC4 armadillo repeat containing 4
ASTN1 astrotactin 1
ATN1 atrophin 1
ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BMP7 bone morphogenetic protein 7
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCL22 chemokine (C-C motif) ligand 22
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD200 CD200 molecule
CDC14A cell division cycle 14A
CDC14B cell division cycle 14B
CHAT choline O-acetyltransferase
CHM choroideremia (Rab escort protein 1)
CNTNAP2 contactin associated protein-like 2
COL10A1 collagen, type X, alpha 1
COPZ2 coatomer protein complex, subunit zeta 2
CPB2 carboxypeptidase B2 (plasma)
CRTC1 CREB regulated transcription coactivator 1
CTSS cathepsin S
DCAF15 DDB1 and CUL4 associated factor 15
DGCR9 DiGeorge syndrome critical region gene 9 (non-protein coding)
DPYSL3 dihydropyrimidinase-like 3
ECE1 endothelin converting enzyme 1
EPHA5 EPH receptor A5
EXOSC2 exosome component 2
EXPH5 exophilin 5
F13A1 coagulation factor XIII, A1 polypeptide
FAS Fas cell surface death receptor
GGT1 gamma-glutamyltransferase 1
GK glycerol kinase
GLP1R glucagon-like peptide 1 receptor
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GRM4 glutamate receptor, metabotropic 4
GTF2I general transcription factor IIi
GZMK granzyme K (granzyme 3; tryptase II)
HMX1 H6 family homeobox 1
HN1L hematological and neurological expressed 1-like
IDS iduronate 2-sulfatase
KCNMB2 potassium channel subfamily M regulatory beta subunit 2
KIAA0319L KIAA0319-like
KIAA1109 KIAA1109
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LOC100294391 uncharacterized LOC100294391
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MEF2C myocyte enhancer factor 2C
METTL7A methyltransferase like 7A
MFN2 mitofusin 2
MOBP myelin-associated oligodendrocyte basic protein
N4BP1 NEDD4 binding protein 1
N4BP2L1 NEDD4 binding protein 2-like 1
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NDOR1 NADPH dependent diflavin oxidoreductase 1
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
NNAT neuronatin
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NPC1 Niemann-Pick disease, type C1
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
OR2B6 olfactory receptor, family 2, subfamily B, member 6
P2RY14 purinergic receptor P2Y, G-protein coupled, 14
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PCYT1B phosphate cytidylyltransferase 1, choline, beta
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLD1 phospholipase D1, phosphatidylcholine-specific
PLK3 polo-like kinase 3
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
R3HCC1L R3H domain and coiled-coil containing 1-like
RARA retinoic acid receptor, alpha
RECQL5 RecQ protein-like 5
RHEB Ras homolog enriched in brain
RUNX1 runt-related transcription factor 1
SERHL2 serine hydrolase-like 2
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SFTPB surfactant protein B
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SPP1 secreted phosphoprotein 1
STAT2 signal transducer and activator of transcription 2, 113kDa
SYT11 synaptotagmin XI
TAT tyrosine aminotransferase
TBL1Y transducin (beta)-like 1, Y-linked
THEMIS2 thymocyte selection associated family member 2
TMEM259 transmembrane protein 259
TMPRSS15 transmembrane protease, serine 15
TNS1 tensin 1
TRIM3 tripartite motif containing 3
TRPM3 transient receptor potential cation channel, subfamily M, member 3
TYRO3 TYRO3 protein tyrosine kinase
WDR55 WD repeat domain 55
WNT16 wingless-type MMTV integration site family, member 16

decreased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
AIM1L absent in melanoma 1-like
AMT aminomethyltransferase
ARC activity-regulated cytoskeleton-associated protein
ARID3B AT rich interactive domain 3B (BRIGHT-like)
BTF3P12 basic transcription factor 3 pseudogene 12
C14ORF79 chromosome 14 open reading frame 79
C1QTNF3 C1q and tumor necrosis factor related protein 3
C1RL complement component 1, r subcomponent-like
C5ORF45 chromosome 5 open reading frame 45
CCDC71 coiled-coil domain containing 71
CDK20 cyclin-dependent kinase 20
CDK3 cyclin-dependent kinase 3
CDON cell adhesion associated, oncogene regulated
CEP41 centrosomal protein 41kDa
CPED1 cadherin-like and PC-esterase domain containing 1
DAGLA diacylglycerol lipase, alpha
DDN dendrin
DIO3 deiodinase, iodothyronine, type III
DLK2 delta-like 2 homolog (Drosophila)
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DSCAM Down syndrome cell adhesion molecule
DUSP2 dual specificity phosphatase 2
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EGLN3 egl-9 family hypoxia-inducible factor 3
EPHA4 EPH receptor A4
ERN2 endoplasmic reticulum to nucleus signaling 2
ERO1LB ERO1-like beta (S. cerevisiae)
EXOSC1 exosome component 1
GAN gigaxonin
GBP2 guanylate binding protein 2, interferon-inducible
GEMIN8 gem (nuclear organelle) associated protein 8
GLS2 glutaminase 2 (liver, mitochondrial)
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPR19 G protein-coupled receptor 19
HDAC7 histone deacetylase 7
HOXB2 homeobox B2
HOXC11 homeobox C11
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
IFI6 interferon, alpha-inducible protein 6
IL15RA interleukin 15 receptor, alpha
IL17RB interleukin 17 receptor B
IRAK4 interleukin-1 receptor-associated kinase 4
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KCTD17 potassium channel tetramerization domain containing 17
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LMTK2 lemur tyrosine kinase 2
LOC100127972 uncharacterized LOC100127972
LRRK1 leucine-rich repeat kinase 1
MAGEH1 melanoma antigen family H1
MAK male germ cell-associated kinase
MBNL3 muscleblind-like splicing regulator 3
MEGF8 multiple EGF-like-domains 8
MRPL41 mitochondrial ribosomal protein L41
MTA2 metastasis associated 1 family, member 2
MXD3 MAX dimerization protein 3
MYLK myosin light chain kinase
NKX3-2 NK3 homeobox 2
NPHP1 nephronophthisis 1 (juvenile)
NT5M 5',3'-nucleotidase, mitochondrial
PADI1 peptidyl arginine deiminase, type I
PAQR4 progestin and adipoQ receptor family member IV
PCBP4 poly(rC) binding protein 4
PCDH17 protocadherin 17
PGP phosphoglycolate phosphatase
PHF14 PHD finger protein 14
PICK1 protein interacting with PRKCA 1
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRR14L proline rich 14-like
RAB4B RAB4B, member RAS oncogene family
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
REM1 RAS (RAD and GEM)-like GTP-binding 1
RNF122 ring finger protein 122
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SAYSD1 SAYSVFN motif domain containing 1
SCGB2A2 secretoglobin, family 2A, member 2
SMO smoothened, frizzled class receptor
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
SYCE1L synaptonemal complex central element protein 1-like
TBKBP1 TBK1 binding protein 1
TCEAL2 transcription elongation factor A (SII)-like 2
TESPA1 thymocyte expressed, positive selection associated 1
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TUBA3C tubulin, alpha 3c
VASP vasodilator-stimulated phosphoprotein
VN1R1 vomeronasal 1 receptor 1
WDR4 WD repeat domain 4
ZNF214 zinc finger protein 214
ZNF528 zinc finger protein 528
ZNF639 zinc finger protein 639
ZNF702P zinc finger protein 702, pseudogene