PNU-0230031-3632 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the PNU-0230031-3632 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABI3BP ABI family, member 3 (NESH) binding protein
AIM2 absent in melanoma 2
ANKH ANKH inorganic pyrophosphate transport regulator
ARHGAP1 Rho GTPase activating protein 1
ASIC1 acid sensing (proton gated) ion channel 1
ATXN7L1 ataxin 7-like 1
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CAPN10 calpain 10
CD36 CD36 molecule (thrombospondin receptor)
CDON cell adhesion associated, oncogene regulated
CHKB choline kinase beta
COL11A1 collagen, type XI, alpha 1
CPEB1 cytoplasmic polyadenylation element binding protein 1
CRHR1 corticotropin releasing hormone receptor 1
CSF1 colony stimulating factor 1 (macrophage)
CTIF CBP80/20-dependent translation initiation factor
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DES desmin
DGAT1 diacylglycerol O-acyltransferase 1
DRD1 dopamine receptor D1
DTNB dystrobrevin, beta
ECE1 endothelin converting enzyme 1
EDN1 endothelin 1
EFR3B EFR3 homolog B (S. cerevisiae)
FLOT1 flotillin 1
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1
GPM6A glycoprotein M6A
GPR161 G protein-coupled receptor 161
GTPBP1 GTP binding protein 1
HNRNPM heterogeneous nuclear ribonucleoprotein M
IFI6 interferon, alpha-inducible protein 6
IGKV1D-13 immunoglobulin kappa variable 1D-13
IL1RN interleukin 1 receptor antagonist
IL36G interleukin 36, gamma
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KANK3 KN motif and ankyrin repeat domains 3
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KLF6 Kruppel-like factor 6
KLHL29 kelch-like family member 29
KMT2A lysine (K)-specific methyltransferase 2A
KRT17 keratin 17, type I
KRT8 keratin 8, type II
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LOC100127972 uncharacterized LOC100127972
LOC644450 uncharacterized LOC644450
LOC647070 uncharacterized LOC647070
LRRC37A3 leucine rich repeat containing 37, member A3
LRRC75B leucine rich repeat containing 75B
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
MMP3 matrix metallopeptidase 3
NABP1 nucleic acid binding protein 1
NDOR1 NADPH dependent diflavin oxidoreductase 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NOP14-AS1 NOP14 antisense RNA 1
NPR2 natriuretic peptide receptor 2
OSBPL10 oxysterol binding protein-like 10
PADI3 peptidyl arginine deiminase, type III
PCDHB12 protocadherin beta 12
PCNXL2 pecanex-like 2 (Drosophila)
PCSK6 proprotein convertase subtilisin/kexin type 6
PDAP1 PDGFA associated protein 1
PDCD6 programmed cell death 6
PDE4DIP phosphodiesterase 4D interacting protein
PDLIM7 PDZ and LIM domain 7 (enigma)
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PKP2 plakophilin 2
PRKG2 protein kinase, cGMP-dependent, type II
RAD52 RAD52 homolog (S. cerevisiae)
RUSC2 RUN and SH3 domain containing 2
SH3BP2 SH3-domain binding protein 2
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLCO2B1 solute carrier organic anion transporter family, member 2B1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPHK2 sphingosine kinase 2
STMN3 stathmin-like 3
STS steroid sulfatase (microsomal), isozyme S
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TAS2R1 taste receptor, type 2, member 1
TGFA transforming growth factor, alpha
TM4SF5 transmembrane 4 L six family member 5
TNPO2 transportin 2
TONSL tonsoku-like, DNA repair protein
TPSG1 tryptase gamma 1
TRABD TraB domain containing
TRIM10 tripartite motif containing 10
UCN urocortin
VEGFB vascular endothelial growth factor B
WDR62 WD repeat domain 62
ZFAND6 zinc finger, AN1-type domain 6
ZIM2 zinc finger, imprinted 2
ZNF154 zinc finger protein 154
ZXDB zinc finger, X-linked, duplicated B

decreased expression

Symbol Name
AIRE autoimmune regulator
AKAP5 A kinase (PRKA) anchor protein 5
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BEGAIN brain-enriched guanylate kinase-associated
BMP10 bone morphogenetic protein 10
C1QB complement component 1, q subcomponent, B chain
CAMK1 calcium/calmodulin-dependent protein kinase I
CCDC71 coiled-coil domain containing 71
CFAP70 cilia and flagella associated protein 70
CFHR4 complement factor H-related 4
CLGN calmegin
CNPY4 canopy FGF signaling regulator 4
CTSD cathepsin D
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DAGLA diacylglycerol lipase, alpha
DAO D-amino-acid oxidase
DEPDC5 DEP domain containing 5
DOK2 docking protein 2, 56kDa
EMP3 epithelial membrane protein 3
EPN1 epsin 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FADS2 fatty acid desaturase 2
FBXO2 F-box protein 2
FFAR2 free fatty acid receptor 2
FGF13 fibroblast growth factor 13
FKBP1B FK506 binding protein 1B, 12.6 kDa
FLJ22184
FOXF2 forkhead box F2
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GSTCD glutathione S-transferase, C-terminal domain containing
HIST1H2AJ histone cluster 1, H2aj
HLA-DMB major histocompatibility complex, class II, DM beta
HOXA4 homeobox A4
HOXC5 homeobox C5
IBSP integrin-binding sialoprotein
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNK5 potassium channel, two pore domain subfamily K, member 5
KCTD17 potassium channel tetramerization domain containing 17
KDM5C lysine (K)-specific demethylase 5C
KIAA1107 KIAA1107
KRT9 keratin 9, type I
MATK megakaryocyte-associated tyrosine kinase
MBNL3 muscleblind-like splicing regulator 3
MOB3B MOB kinase activator 3B
MYO1F myosin IF
MYOZ3 myozenin 3
NPTX1 neuronal pentraxin I
NPTX2 neuronal pentraxin II
NPY4R neuropeptide Y receptor Y4
OLFML2A olfactomedin-like 2A
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
OVOL1 ovo-like zinc finger 1
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDE8B phosphodiesterase 8B
PGR progesterone receptor
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLK3 polo-like kinase 3
PRKCE protein kinase C, epsilon
PRSS53 protease, serine, 53
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
RAD54L2 RAD54-like 2 (S. cerevisiae)
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RHOBTB2 Rho-related BTB domain containing 2
RLN1 relaxin 1
RNF122 ring finger protein 122
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPGRIP1L RPGRIP1-like
RPL10L ribosomal protein L10-like
S100A2 S100 calcium binding protein A2
SCAI suppressor of cancer cell invasion
SDC3 syndecan 3
SDS serine dehydratase
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SGCE sarcoglycan, epsilon
SLC16A4 solute carrier family 16, member 4
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC35G2 solute carrier family 35, member G2
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
TBL1Y transducin (beta)-like 1, Y-linked
TCTN2 tectonic family member 2
TFDP3 transcription factor Dp family, member 3
TLR2 toll-like receptor 2
TMEM104 transmembrane protein 104
TRIM21 tripartite motif containing 21
TSNAXIP1 translin-associated factor X interacting protein 1
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
VAX2 ventral anterior homeobox 2
VIPR1 vasoactive intestinal peptide receptor 1
WDR78 WD repeat domain 78
ZNF639 zinc finger protein 639
ZNF76 zinc finger protein 76