PHA-767491 Gene Set

Dataset LINCS KinomeScan Kinase Inhibitor Targets
Category physical interactions
Type small molecule
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Genes

58 kinases inhibited by the PHA-767491 small molecule from the KinomeScan Kinase Inhibitor Targets dataset.

Symbol Name Standardized Value
IRAK1 interleukin-1 receptor-associated kinase 1 1.36211
MAPK15 mitogen-activated protein kinase 15 1.36211
CSNK1E casein kinase 1, epsilon 1.36211
CIT citron rho-interacting serine/threonine kinase 1.36211
CLK1 CDC-like kinase 1 1.36211
BMPR1B bone morphogenetic protein receptor, type IB 1.35325
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 1.34449
STK17A serine/threonine kinase 17a 1.34449
CLK4 CDC-like kinase 4 1.33582
CSNK1G3 casein kinase 1, gamma 3 1.33582
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B 1.32726
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 1.32726
CDK9 cyclin-dependent kinase 9 1.32726
CLK2 CDC-like kinase 2 1.32726
CSNK1D casein kinase 1, delta 1.32726
GSK3B glycogen synthase kinase 3 beta 1.31878
DCLK3 doublecortin-like kinase 3 1.3104
CSNK1A1L casein kinase 1, alpha 1-like 1.3104
TAOK1 TAO kinase 1 1.30212
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 1.29393
HIPK1 homeodomain interacting protein kinase 1 1.29393
TAOK3 TAO kinase 3 1.28583
CLK3 CDC-like kinase 3 1.26991
DAPK1 death-associated protein kinase 1 1.25436
PLK1 polo-like kinase 1 1.25436
CDK7 cyclin-dependent kinase 7 1.2317
DAPK3 death-associated protein kinase 3 1.2317
CSNK2A2 casein kinase 2, alpha prime polypeptide 1.22432
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 1.20983
DAPK2 death-associated protein kinase 2 1.19568
HIPK4 homeodomain interacting protein kinase 4 1.18873
HIPK3 homeodomain interacting protein kinase 3 1.15523
CSNK2A1 casein kinase 2, alpha 1 polypeptide 1.1424
AAK1 AP2 associated kinase 1 1.12988
ACVR2A activin A receptor, type IIA 1.11767
PKN2 protein kinase N2 1.10576
HIPK2 homeodomain interacting protein kinase 2 1.09992
RIPK4 receptor-interacting serine-threonine kinase 4 1.09992
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 1.0718
CDKL5 cyclin-dependent kinase-like 5 1.05577
NUAK2 NUAK family, SNF1-like kinase, 2 1.05057
PKN1 protein kinase N1 1.03041
TAOK2 TAO kinase 2 1.03041
STK35 serine/threonine kinase 35 1.03041
ACVR2B activin A receptor, type IIB 0.984392
ULK2 unc-51 like autophagy activating kinase 2 0.967615
STK33 serine/threonine kinase 33 0.959553
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.922275
MUSK muscle, skeletal, receptor tyrosine kinase 0.922275
CDK8 cyclin-dependent kinase 8 0.915387
LATS2 large tumor suppressor kinase 2 0.908676
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.889549
PLK3 polo-like kinase 3 0.883492
MINK1 misshapen-like kinase 1 0.883492
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.866209
MYLK myosin light chain kinase 0.855378
CAMK2B calcium/calmodulin-dependent protein kinase II beta 0.850157
PIM2 Pim-2 proto-oncogene, serine/threonine kinase 0.850157