PHA-00851261E-3968 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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195 genes differentially expressed following the PHA-00851261E-3968 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AIM1L absent in melanoma 1-like
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ANKH ANKH inorganic pyrophosphate transport regulator
AOC3 amine oxidase, copper containing 3
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ARHGAP1 Rho GTPase activating protein 1
ARHGAP25 Rho GTPase activating protein 25
ARHGAP26 Rho GTPase activating protein 26
ARL4D ADP-ribosylation factor-like 4D
ART1 ADP-ribosyltransferase 1
ARTN artemin
ASTN1 astrotactin 1
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C1ORF95 chromosome 1 open reading frame 95
C1QTNF1 C1q and tumor necrosis factor related protein 1
CAPN2 calpain 2, (m/II) large subunit
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CEP112 centrosomal protein 112kDa
CFAP45 cilia and flagella associated protein 45
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CLEC1A C-type lectin domain family 1, member A
COL16A1 collagen, type XVI, alpha 1
COLEC12 collectin sub-family member 12
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DPF1 D4, zinc and double PHD fingers family 1
EDIL3 EGF-like repeats and discoidin I-like domains 3
EPN1 epsin 1
FGF21 fibroblast growth factor 21
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FRMD8 FERM domain containing 8
FRZB frizzled-related protein
GEMIN7 gem (nuclear organelle) associated protein 7
HAB1 B1 for mucin
HBB hemoglobin, beta
HDAC7 histone deacetylase 7
HHAT hedgehog acyltransferase
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
HYAL3 hyaluronoglucosaminidase 3
ICOSLG inducible T-cell co-stimulator ligand
IGKV1D-13 immunoglobulin kappa variable 1D-13
IL1RN interleukin 1 receptor antagonist
LAT2 linker for activation of T cells family, member 2
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MAGEA5 melanoma antigen family A5
MARK1 MAP/microtubule affinity-regulating kinase 1
MMP16 matrix metallopeptidase 16 (membrane-inserted)
NCOR2 nuclear receptor corepressor 2
NEFL neurofilament, light polypeptide
NR2E3 nuclear receptor subfamily 2, group E, member 3
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PCDHGC3 protocadherin gamma subfamily C, 3
PCSK6 proprotein convertase subtilisin/kexin type 6
PGAP3 post-GPI attachment to proteins 3
PHF20L1 PHD finger protein 20-like 1
PHF8 PHD finger protein 8
PHOX2A paired-like homeobox 2a
PKNOX2 PBX/knotted 1 homeobox 2
PLK3 polo-like kinase 3
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PQLC2 PQ loop repeat containing 2
PRAMEF10 PRAME family member 10
PTAFR platelet-activating factor receptor
PTPN1 protein tyrosine phosphatase, non-receptor type 1
RASL12 RAS-like, family 12
RGS14 regulator of G-protein signaling 14
RHOH ras homolog family member H
RPS4Y1 ribosomal protein S4, Y-linked 1
SAFB scaffold attachment factor B
SCAND2P SCAN domain containing 2 pseudogene
SECTM1 secreted and transmembrane 1
SERHL2 serine hydrolase-like 2
SH2D2A SH2 domain containing 2A
SH3D21 SH3 domain containing 21
SH3PXD2A SH3 and PX domains 2A
SLC45A2 solute carrier family 45, member 2
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SNCG synuclein, gamma (breast cancer-specific protein 1)
SOX18 SRY (sex determining region Y)-box 18
SOX2 SRY (sex determining region Y)-box 2
SRRT serrate, RNA effector molecule
SSTR5 somatostatin receptor 5
STAT4 signal transducer and activator of transcription 4
T T, brachyury homolog (mouse)
THAP3 THAP domain containing, apoptosis associated protein 3
THBS4 thrombospondin 4
TMOD1 tropomodulin 1
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNS1 tensin 1
UBA6 ubiquitin-like modifier activating enzyme 6
USH1C Usher syndrome 1C (autosomal recessive, severe)
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae)
ZFP2 ZFP2 zinc finger protein
ZNF280A zinc finger protein 280A
ZNF335 zinc finger protein 335

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ACPP acid phosphatase, prostate
ANP32A-IT1 ANP32A intronic transcript 1
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ATAT1 alpha tubulin acetyltransferase 1
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BCL9 B-cell CLL/lymphoma 9
BMP15 bone morphogenetic protein 15
BTNL3 butyrophilin-like 3
C10ORF95 chromosome 10 open reading frame 95
C11ORF30 chromosome 11 open reading frame 30
C5ORF45 chromosome 5 open reading frame 45
CAMK1 calcium/calmodulin-dependent protein kinase I
CD3D CD3d molecule, delta (CD3-TCR complex)
CD83 CD83 molecule
CDHR2 cadherin-related family member 2
CDK20 cyclin-dependent kinase 20
CDK3 cyclin-dependent kinase 3
CDON cell adhesion associated, oncogene regulated
CIDEB cell death-inducing DFFA-like effector b
CLCN6 chloride channel, voltage-sensitive 6
CLEC4E C-type lectin domain family 4, member E
CLIP4 CAP-GLY domain containing linker protein family, member 4
CLSPN claspin
CORT cortistatin
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DOK5 docking protein 5
DRD1 dopamine receptor D1
EHMT1 euchromatic histone-lysine N-methyltransferase 1
F9 coagulation factor IX
FAM186A family with sequence similarity 186, member A
FFAR2 free fatty acid receptor 2
FGD1 FYVE, RhoGEF and PH domain containing 1
FLCN folliculin
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPR27 G protein-coupled receptor 27
GSTM5 glutathione S-transferase mu 5
GSTTP1 glutathione S-transferase theta pseudogene 1
HIST1H4D histone cluster 1, H4d
HIST1H4F histone cluster 1, H4f
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
IFNA17 interferon, alpha 17
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
JAM3 junctional adhesion molecule 3
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNK2 potassium channel, two pore domain subfamily K, member 2
KLF8 Kruppel-like factor 8
KREMEN2 kringle containing transmembrane protein 2
KRT86 keratin 86, type II
LRRC37A3 leucine rich repeat containing 37, member A3
MAGEB2 melanoma antigen family B2
MFGE8 milk fat globule-EGF factor 8 protein
NAT6 N-acetyltransferase 6 (GCN5-related)
NLGN1 neuroligin 1
NPY4R neuropeptide Y receptor Y4
OCA2 oculocutaneous albinism II
ONECUT1 one cut homeobox 1
PAX9 paired box 9
PLAC4 placenta-specific 4
POLM polymerase (DNA directed), mu
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRF1 perforin 1 (pore forming protein)
PRKCE protein kinase C, epsilon
PRSS16 protease, serine, 16 (thymus)
PYHIN1 pyrin and HIN domain family, member 1
QPCT glutaminyl-peptide cyclotransferase
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RHBG Rh family, B glycoprotein (gene/pseudogene)
RIN1 Ras and Rab interactor 1
RNF126P1 ring finger protein 126 pseudogene 1
SCGB2A2 secretoglobin, family 2A, member 2
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SPRR1B small proline-rich protein 1B
TAOK1 TAO kinase 1
TEP1 telomerase-associated protein 1
TEX40 testis expressed 40
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TLR2 toll-like receptor 2
TM4SF4 transmembrane 4 L six family member 4
TMCC2 transmembrane and coiled-coil domain family 2
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
UBTD1 ubiquitin domain containing 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UPP1 uridine phosphorylase 1
XDH xanthine dehydrogenase
XYLT2 xylosyltransferase II
ZBTB48 zinc finger and BTB domain containing 48
ZNF37BP zinc finger protein 37B, pseudogene
ZNF639 zinc finger protein 639