PHA-00851261E-3854 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the PHA-00851261E-3854 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ABHD2 abhydrolase domain containing 2
ADGRG1 adhesion G protein-coupled receptor G1
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
AOC3 amine oxidase, copper containing 3
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BTG2 BTG family, member 2
BTN3A1 butyrophilin, subfamily 3, member A1
C11ORF16 chromosome 11 open reading frame 16
CA5B carbonic anhydrase VB, mitochondrial
CD34 CD34 molecule
CPNE7 copine VII
CREBZF CREB/ATF bZIP transcription factor
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein)
CXORF21 chromosome X open reading frame 21
CYTH1 cytohesin 1
DAPK3 death-associated protein kinase 3
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DNASE1L3 deoxyribonuclease I-like 3
DST dystonin
DTNA dystrobrevin, alpha
ESR1 estrogen receptor 1
FKRP fukutin related protein
FLJ11292
FLOT1 flotillin 1
FUS FUS RNA binding protein
GFI1 growth factor independent 1 transcription repressor
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GOLGA2P5 golgin A2 pseudogene 5
GOLGA8A golgin A8 family, member A
GPR161 G protein-coupled receptor 161
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HFE hemochromatosis
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HPCAL4 hippocalcin like 4
HR hair growth associated
HRASLS HRAS-like suppressor
HTATSF1 HIV-1 Tat specific factor 1
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IL17RC interleukin 17 receptor C
IL1RN interleukin 1 receptor antagonist
IL6ST interleukin 6 signal transducer
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
KITLG KIT ligand
KLF13 Kruppel-like factor 13
KLHL25 kelch-like family member 25
KMT2A lysine (K)-specific methyltransferase 2A
LONRF3 LON peptidase N-terminal domain and ring finger 3
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MAN1A2 mannosidase, alpha, class 1A, member 2
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MCOLN1 mucolipin 1
METTL16 methyltransferase like 16
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NAT6 N-acetyltransferase 6 (GCN5-related)
NCOR2 nuclear receptor corepressor 2
NDRG2 NDRG family member 2
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2
PAIP2B poly(A) binding protein interacting protein 2B
PARVB parvin, beta
PDAP1 PDGFA associated protein 1
PDE12 phosphodiesterase 12
PDE4C phosphodiesterase 4C, cAMP-specific
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLK4 polo-like kinase 4
PPP4R4 protein phosphatase 4, regulatory subunit 4
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PVR poliovirus receptor
QTRT1 queuine tRNA-ribosyltransferase 1
RB1 retinoblastoma 1
RBL2 retinoblastoma-like 2
RNF6 ring finger protein (C3H2C3 type) 6
RPS3A ribosomal protein S3A
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
SCAND2P SCAN domain containing 2 pseudogene
SLC45A2 solute carrier family 45, member 2
SNCAIP synuclein, alpha interacting protein
SP1 Sp1 transcription factor
SPRED2 sprouty-related, EVH1 domain containing 2
STOML1 stomatin (EPB72)-like 1
TAS2R1 taste receptor, type 2, member 1
TRA2A transformer 2 alpha homolog (Drosophila)
TSC2 tuberous sclerosis 2
TTC39A tetratricopeptide repeat domain 39A
UCN urocortin
WASL Wiskott-Aldrich syndrome-like
WDR78 WD repeat domain 78
ZFP2 ZFP2 zinc finger protein
ZNF137P zinc finger protein 137, pseudogene
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
AFAP1 actin filament associated protein 1
AKAP12 A kinase (PRKA) anchor protein 12
AMPD1 adenosine monophosphate deaminase 1
ANKH ANKH inorganic pyrophosphate transport regulator
ARMCX5 armadillo repeat containing, X-linked 5
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BAG4 BCL2-associated athanogene 4
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
C4BPA complement component 4 binding protein, alpha
C5AR2 complement component 5a receptor 2
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC132 coiled-coil domain containing 132
CD80 CD80 molecule
CGA glycoprotein hormones, alpha polypeptide
COBL cordon-bleu WH2 repeat protein
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DNAAF2 dynein, axonemal, assembly factor 2
DOC2A double C2-like domains, alpha
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EAF2 ELL associated factor 2
EFNA3 ephrin-A3
ELP6 elongator acetyltransferase complex subunit 6
ENOX1 ecto-NOX disulfide-thiol exchanger 1
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FLT4 fms-related tyrosine kinase 4
FSTL3 follistatin-like 3 (secreted glycoprotein)
FXYD5 FXYD domain containing ion transport regulator 5
GMPR guanosine monophosphate reductase
GPATCH3 G patch domain containing 3
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GSTA4 glutathione S-transferase alpha 4
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H1B histone cluster 1, H1b
HIST1H4C histone cluster 1, H4c
HOXB2 homeobox B2
IFI6 interferon, alpha-inducible protein 6
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IL22 interleukin 22
KCNK12 potassium channel, two pore domain subfamily K, member 12
KIAA1107 KIAA1107
KLF2 Kruppel-like factor 2
KREMEN2 kringle containing transmembrane protein 2
KRT16 keratin 16, type I
MAN2C1 mannosidase, alpha, class 2C, member 1
MAP1S microtubule-associated protein 1S
MFAP2 microfibrillar-associated protein 2
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MMP2 matrix metallopeptidase 2
PCDH17 protocadherin 17
PCDHGA8 protocadherin gamma subfamily A, 8
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCD1 phospholipase C, delta 1
POLL polymerase (DNA directed), lambda
POMT2 protein-O-mannosyltransferase 2
PRKX protein kinase, X-linked
PTPRS protein tyrosine phosphatase, receptor type, S
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RPL13P5 ribosomal protein L13 pseudogene 5
S100A9 S100 calcium binding protein A9
SECTM1 secreted and transmembrane 1
SKI SKI proto-oncogene
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLPI secretory leukocyte peptidase inhibitor
SPIDR scaffolding protein involved in DNA repair
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
TAOK1 TAO kinase 1
TBC1D19 TBC1 domain family, member 19
TBL1Y transducin (beta)-like 1, Y-linked
TEAD3 TEA domain family member 3
TESC tescalcin
TEX40 testis expressed 40
THRAP3 thyroid hormone receptor associated protein 3
TMEM242 transmembrane protein 242
TMEM62 transmembrane protein 62
TONSL tonsoku-like, DNA repair protein
TRIM68 tripartite motif containing 68
TUBA4B tubulin, alpha 4b
VASH1 vasohibin 1
VPS9D1 VPS9 domain containing 1
WDR91 WD repeat domain 91
WFDC2 WAP four-disulfide core domain 2
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZFP37 ZFP37 zinc finger protein
ZNF226 zinc finger protein 226
ZNF358 zinc finger protein 358
ZNF484 zinc finger protein 484
ZNF747 zinc finger protein 747
ZSCAN2 zinc finger and SCAN domain containing 2