PHA-00851261E-3776 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the PHA-00851261E-3776 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A2M alpha-2-macroglobulin
AADAC arylacetamide deacetylase
ACSM3 acyl-CoA synthetase medium-chain family member 3
ADCK4 aarF domain containing kinase 4
AFF1 AF4/FMR2 family, member 1
AGBL3 ATP/GTP binding protein-like 3
ALPK3 alpha-kinase 3
ALPP alkaline phosphatase, placental
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15
ARID5A AT rich interactive domain 5A (MRF1-like)
BAGE B melanoma antigen
BCAM basal cell adhesion molecule (Lutheran blood group)
CADM4 cell adhesion molecule 4
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCDC70 coiled-coil domain containing 70
CD33 CD33 molecule
CDHR2 cadherin-related family member 2
CDK2 cyclin-dependent kinase 2
CEMIP cell migration inducing protein, hyaluronan binding
CIZ1 CDKN1A interacting zinc finger protein 1
CNKSR2 connector enhancer of kinase suppressor of Ras 2
CNPY4 canopy FGF signaling regulator 4
CPEB3 cytoplasmic polyadenylation element binding protein 3
CRAT carnitine O-acetyltransferase
CRHR2 corticotropin releasing hormone receptor 2
CSF1R colony stimulating factor 1 receptor
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DOPEY2 dopey family member 2
EGFL7 EGF-like-domain, multiple 7
EPB41L4A erythrocyte membrane protein band 4.1 like 4A
ESR1 estrogen receptor 1
EXOSC1 exosome component 1
EYA3 EYA transcriptional coactivator and phosphatase 3
FGF4 fibroblast growth factor 4
FSCN2 fascin actin-bundling protein 2, retinal
FYB FYN binding protein
GBP1 guanylate binding protein 1, interferon-inducible
GFRA1 GDNF family receptor alpha 1
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPC3 glypican 3
GYG2 glycogenin 2
GZMM granzyme M (lymphocyte met-ase 1)
ICOSLG inducible T-cell co-stimulator ligand
IGF1R insulin-like growth factor 1 receptor
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IL32 interleukin 32
ING4 inhibitor of growth family, member 4
KAT8 K(lysine) acetyltransferase 8
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
LOC284244 uncharacterized LOC284244
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LTK leukocyte receptor tyrosine kinase
MAP3K13 mitogen-activated protein kinase kinase kinase 13
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MARK2 MAP/microtubule affinity-regulating kinase 2
MEG3 maternally expressed 3 (non-protein coding)
MEOX2 mesenchyme homeobox 2
MMP16 matrix metallopeptidase 16 (membrane-inserted)
NF1 neurofibromin 1
NRCAM neuronal cell adhesion molecule
NUMA1 nuclear mitotic apparatus protein 1
OR3A3 olfactory receptor, family 3, subfamily A, member 3
PAPPA2 pappalysin 2
PCYT1B phosphate cytidylyltransferase 1, choline, beta
PDLIM4 PDZ and LIM domain 4
PGAP3 post-GPI attachment to proteins 3
PHTF2 putative homeodomain transcription factor 2
PLCH2 phospholipase C, eta 2
POU4F2 POU class 4 homeobox 2
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PSG9 pregnancy specific beta-1-glycoprotein 9
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
RAB6B RAB6B, member RAS oncogene family
RFPL2 ret finger protein-like 2
RGR retinal G protein coupled receptor
RND1 Rho family GTPase 1
RNF208 ring finger protein 208
RPL23AP53 ribosomal protein L23a pseudogene 53
SCAPER S-phase cyclin A-associated protein in the ER
SHOX2 short stature homeobox 2
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SMO smoothened, frizzled class receptor
SNCA synuclein, alpha (non A4 component of amyloid precursor)
STAT2 signal transducer and activator of transcription 2, 113kDa
STK24 serine/threonine kinase 24
SYT2 synaptotagmin II
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
TBKBP1 TBK1 binding protein 1
TCP10 t-complex 10
TMPRSS11D transmembrane protease, serine 11D
TSC22D2 TSC22 domain family, member 2
ULK2 unc-51 like autophagy activating kinase 2
VAMP5 vesicle-associated membrane protein 5
ZNF287 zinc finger protein 287

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ACSS3 acyl-CoA synthetase short-chain family member 3
ADAM23 ADAM metallopeptidase domain 23
ADTRP androgen-dependent TFPI-regulating protein
ARHGAP22 Rho GTPase activating protein 22
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARMC4 armadillo repeat containing 4
ATG10 autophagy related 10
AUH AU RNA binding protein/enoyl-CoA hydratase
BIRC7 baculoviral IAP repeat containing 7
C1ORF54 chromosome 1 open reading frame 54
C22ORF46 chromosome 22 open reading frame 46
CAMK4 calcium/calmodulin-dependent protein kinase IV
CBS cystathionine-beta-synthase
CCDC134 coiled-coil domain containing 134
CD34 CD34 molecule
CES3 carboxylesterase 3
CNTLN centlein, centrosomal protein
COLGALT2 collagen beta(1-O)galactosyltransferase 2
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DEAF1 DEAF1 transcription factor
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DPF3 D4, zinc and double PHD fingers, family 3
EPB41L5 erythrocyte membrane protein band 4.1 like 5
FBXL15 F-box and leucine-rich repeat protein 15
FBXO2 F-box protein 2
FGF23 fibroblast growth factor 23
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FUZ fuzzy planar cell polarity protein
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HIRA histone cell cycle regulator
HIST1H2AL histone cluster 1, H2al
HMGB3P1 high mobility group box 3 pseudogene 1
HOXC11 homeobox C11
IFNA17 interferon, alpha 17
IL12A interleukin 12A
INO80D INO80 complex subunit D
INPP5J inositol polyphosphate-5-phosphatase J
ITGA10 integrin, alpha 10
KCNIP1 Kv channel interacting protein 1
KRT9 keratin 9, type I
LIMD2 LIM domain containing 2
LINC00472 long intergenic non-protein coding RNA 472
LOC100286895 cell division cycle 27 homolog pseudogene
LRRC15 leucine rich repeat containing 15
LY86 lymphocyte antigen 86
MAP3K7CL MAP3K7 C-terminal like
MCTP1 multiple C2 domains, transmembrane 1
MGC12488
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
NDP Norrie disease (pseudoglioma)
NEK11 NIMA-related kinase 11
NEURL1 neuralized E3 ubiquitin protein ligase 1
NPM3 nucleophosmin/nucleoplasmin 3
OLFML2A olfactomedin-like 2A
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PALM paralemmin
PAQR5 progestin and adipoQ receptor family member V
PAX9 paired box 9
PCDHGB5 protocadherin gamma subfamily B, 5
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PHF14 PHD finger protein 14
PICK1 protein interacting with PRKCA 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
POLL polymerase (DNA directed), lambda
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRR15L proline rich 15-like
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
R3HCC1L R3H domain and coiled-coil containing 1-like
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RBMS3 RNA binding motif, single stranded interacting protein 3
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RPH3A rabphilin 3A
RPL23AP32 ribosomal protein L23a pseudogene 32
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SETD8 SET domain containing (lysine methyltransferase) 8
SNHG3 small nucleolar RNA host gene 3
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STAB2 stabilin 2
STRN striatin, calmodulin binding protein
STXBP5L syntaxin binding protein 5-like
TAOK1 TAO kinase 1
TMEM206 transmembrane protein 206
TRIM25 tripartite motif containing 25
TUBA4B tubulin, alpha 4b
VGF VGF nerve growth factor inducible
WT1-AS WT1 antisense RNA
ZNF234 zinc finger protein 234
ZNF528 zinc finger protein 528
ZNF747 zinc finger protein 747
ZNF778 zinc finger protein 778
ZNF862 zinc finger protein 862