PHA-00816795-7072 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the PHA-00816795-7072 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AARSD1 alanyl-tRNA synthetase domain containing 1
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACOX3 acyl-CoA oxidase 3, pristanoyl
ALG12 ALG12, alpha-1,6-mannosyltransferase
ANOS1 anosmin 1
ARHGAP26 Rho GTPase activating protein 26
B4GALT7 xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7
BAG1 BCL2-associated athanogene
BIN1 bridging integrator 1
C16ORF59 chromosome 16 open reading frame 59
C6ORF106 chromosome 6 open reading frame 106
CACYBP calcyclin binding protein
CCRL2 chemokine (C-C motif) receptor-like 2
CD70 CD70 molecule
CES2 carboxylesterase 2
CREB3L1 cAMP responsive element binding protein 3-like 1
CSF1R colony stimulating factor 1 receptor
CTSF cathepsin F
CXCL5 chemokine (C-X-C motif) ligand 5
DAZAP2 DAZ associated protein 2
DENND2D DENN/MADD domain containing 2D
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EGLN2 egl-9 family hypoxia-inducible factor 2
EIF1 eukaryotic translation initiation factor 1
EPPK1 epiplakin 1
FAM174B family with sequence similarity 174, member B
FLCN folliculin
GLTSCR1L GLTSCR1-like
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
HDAC7 histone deacetylase 7
HGH1 HGH1 homolog (S. cerevisiae)
HIST1H4D histone cluster 1, H4d
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HLX H2.0-like homeobox
HOMER3 homer scaffolding protein 3
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
IL15RA interleukin 15 receptor, alpha
JUN jun proto-oncogene
KAZN kazrin, periplakin interacting protein
KIAA1644 KIAA1644
KLF2 Kruppel-like factor 2
LDB1 LIM domain binding 1
LIMK2 LIM domain kinase 2
LRRK1 leucine-rich repeat kinase 1
MAGOH2P mago-nashi homolog 2, pseudogene
MBTD1 mbt domain containing 1
MCM9 minichromosome maintenance complex component 9
MED22 mediator complex subunit 22
MFGE8 milk fat globule-EGF factor 8 protein
MGC12488
MTUS1 microtubule associated tumor suppressor 1
MXD4 MAX dimerization protein 4
NAAA N-acylethanolamine acid amidase
NCAPH2 non-SMC condensin II complex, subunit H2
NCLN nicalin
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
ORAI3 ORAI calcium release-activated calcium modulator 3
PDCD6 programmed cell death 6
PDE4DIP phosphodiesterase 4D interacting protein
PEX1 peroxisomal biogenesis factor 1
PGPEP1 pyroglutamyl-peptidase I
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PPT2 palmitoyl-protein thioesterase 2
PSIP1 PC4 and SFRS1 interacting protein 1
RHBDD3 rhomboid domain containing 3
RNASE4 ribonuclease, RNase A family, 4
RNF123 ring finger protein 123
RNF126P1 ring finger protein 126 pseudogene 1
RNF19B ring finger protein 19B
SH2D2A SH2 domain containing 2A
SIRT6 sirtuin 6
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SMAD6 SMAD family member 6
SMC1A structural maintenance of chromosomes 1A
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa
SOX12 SRY (sex determining region Y)-box 12
SPTAN1 spectrin, alpha, non-erythrocytic 1
SRCAP Snf2-related CREBBP activator protein
SSH3 slingshot protein phosphatase 3
STK38L serine/threonine kinase 38 like
SYT1 synaptotagmin I
SYT17 synaptotagmin XVII
TAGLN3 transgelin 3
TAOK1 TAO kinase 1
TBC1D4 TBC1 domain family, member 4
TECPR2 tectonin beta-propeller repeat containing 2
TOB2 transducer of ERBB2, 2
TTC38 tetratricopeptide repeat domain 38
TUBA3C tubulin, alpha 3c
UBQLN4 ubiquilin 4
VPRBP Vpr (HIV-1) binding protein
WNK1 WNK lysine deficient protein kinase 1
ZMYND8 zinc finger, MYND-type containing 8
ZNF254 zinc finger protein 254
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
AATF apoptosis antagonizing transcription factor
ALS2CL ALS2 C-terminal like
ANG angiogenin, ribonuclease, RNase A family, 5
ANKFY1 ankyrin repeat and FYVE domain containing 1
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARL15 ADP-ribosylation factor-like 15
ASB7 ankyrin repeat and SOCS box containing 7
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BCL9 B-cell CLL/lymphoma 9
BIK BCL2-interacting killer (apoptosis-inducing)
C19ORF54 chromosome 19 open reading frame 54
C1ORF56 chromosome 1 open reading frame 56
CAND2 cullin-associated and neddylation-dissociated 2 (putative)
CCDC6 coiled-coil domain containing 6
CCDC68 coiled-coil domain containing 68
CCDC85C coiled-coil domain containing 85C
CENPQ centromere protein Q
CFAP44 cilia and flagella associated protein 44
CHML choroideremia-like (Rab escort protein 2)
CLIP4 CAP-GLY domain containing linker protein family, member 4
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CRY2 cryptochrome circadian clock 2
CRYBA2 crystallin, beta A2
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DEPTOR DEP domain containing MTOR-interacting protein
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DTX2 deltex 2, E3 ubiquitin ligase
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EFNA3 ephrin-A3
ELP3 elongator acetyltransferase complex subunit 3
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FNTB farnesyltransferase, CAAX box, beta
FSTL3 follistatin-like 3 (secreted glycoprotein)
FZD8 frizzled class receptor 8
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GDAP1 ganglioside induced differentiation associated protein 1
GRAMD1C GRAM domain containing 1C
IER3IP1 immediate early response 3 interacting protein 1
KDM8 lysine (K)-specific demethylase 8
KIAA0355 KIAA0355
LOC390998 ribosomal protein L10 pseudogene
MANEA mannosidase, endo-alpha
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MKLN1 muskelin 1, intracellular mediator containing kelch motifs
MON1B MON1 secretory trafficking family member B
MOXD1 monooxygenase, DBH-like 1
MPDU1 mannose-P-dolichol utilization defect 1
MTMR12 myotubularin related protein 12
NDE1 nudE neurodevelopment protein 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NID2 nidogen 2 (osteonidogen)
NTSR1 neurotensin receptor 1 (high affinity)
NYNRIN NYN domain and retroviral integrase containing
PCBP4 poly(rC) binding protein 4
PCSK7 proprotein convertase subtilisin/kexin type 7
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLA2G15 phospholipase A2, group XV
PLEKHO1 pleckstrin homology domain containing, family O member 1
RABGGTA Rab geranylgeranyltransferase, alpha subunit
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RPAP2 RNA polymerase II associated protein 2
SHROOM2 shroom family member 2
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC25A40 solute carrier family 25, member 40
SLC41A3 solute carrier family 41, member 3
SNTA1 syntrophin, alpha 1
ST5 suppression of tumorigenicity 5
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast)
TMEM209 transmembrane protein 209
TMEM62 transmembrane protein 62
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNRC6B trinucleotide repeat containing 6B
TRAPPC6A trafficking protein particle complex 6A
TSPAN1 tetraspanin 1
TTC26 tetratricopeptide repeat domain 26
UNC93B1 unc-93 homolog B1 (C. elegans)
USP19 ubiquitin specific peptidase 19
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WDR25 WD repeat domain 25
WDR91 WD repeat domain 91
WWC2 WW and C2 domain containing 2
ZBTB38 zinc finger and BTB domain containing 38
ZFHX3 zinc finger homeobox 3
ZNF124 zinc finger protein 124
ZNF134 zinc finger protein 134
ZNF197 zinc finger protein 197
ZNF324 zinc finger protein 324
ZNF394 zinc finger protein 394
ZNF606 zinc finger protein 606
ZNF654 zinc finger protein 654
ZNF804A zinc finger protein 804A