Osteoarthritis, Hip Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
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Genes

60 genes associated with the Osteoarthritis, Hip phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
ASPN asporin
BAG6 BCL2-associated athanogene 6
BCL9 B-cell CLL/lymphoma 9
BMP5 bone morphogenetic protein 5
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CALM2 calmodulin 2 (phosphorylase kinase, delta)
CAMK2B calcium/calmodulin-dependent protein kinase II beta
COG5 component of oligomeric golgi complex 5
COL10A1 collagen, type X, alpha 1
COL11A1 collagen, type XI, alpha 1
COL1A1 collagen, type I, alpha 1
COL2A1 collagen, type II, alpha 1
COL9A1 collagen, type IX, alpha 1
COL9A2 collagen, type IX, alpha 2
COL9A3 collagen, type IX, alpha 3
COMP cartilage oligomeric matrix protein
COMT catechol-O-methyltransferase
CXCL8 chemokine (C-X-C motif) ligand 8
DIO2 deiodinase, iodothyronine, type II
DOT1L DOT1-like histone H3K79 methyltransferase
DVL2 dishevelled segment polarity protein 2
ESR1 estrogen receptor 1
FAM46A family with sequence similarity 46, member A
FRZB frizzled-related protein
FTO fat mass and obesity associated
FZD5 frizzled class receptor 5
GDF5 growth differentiation factor 5
GHR growth hormone receptor
GHRHR growth hormone releasing hormone receptor
GPR22 G protein-coupled receptor 22
HFE hemochromatosis
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
IGFBP7 insulin-like growth factor binding protein 7
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL6 interleukin 6
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRP5 low density lipoprotein receptor-related protein 5
LRP6 low density lipoprotein receptor-related protein 6
MEFV Mediterranean fever
MMP1 matrix metallopeptidase 1
MMP13 matrix metallopeptidase 13
MMP3 matrix metallopeptidase 3
NCOA3 nuclear receptor coactivator 3
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
SFRP1 secreted frizzled-related protein 1
SFRP4 secreted frizzled-related protein 4
SMAD3 SMAD family member 3
SOST sclerostin
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TGFB1 transforming growth factor, beta 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
WNT1 wingless-type MMTV integration site family, member 1
WNT10A wingless-type MMTV integration site family, member 10A
WNT16 wingless-type MMTV integration site family, member 16
WNT4 wingless-type MMTV integration site family, member 4