Oral Ulcer Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A stomatitis characterized by the repeated formation of benign and non-contagious mouth ulcers. (Human Disease Ontology, DOID_9663)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D019226
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Genes

103 genes/proteins associated with the disease Oral Ulcer from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
LEP leptin 2.88009
EDN1 endothelin 1 2.88009
TNF tumor necrosis factor 1.50549
IL4 interleukin 4 1.46648
IFNG interferon, gamma 1.45326
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.41313
IL6 interleukin 6 1.41285
VCAM1 vascular cell adhesion molecule 1 1.38612
TP53 tumor protein p53 1.38527
TGFB1 transforming growth factor, beta 1 1.37958
BAX BCL2-associated X protein 1.3736
FAS Fas cell surface death receptor 1.36361
IL2 interleukin 2 1.35849
VEGFA vascular endothelial growth factor A 1.35589
IGF1 insulin-like growth factor 1 (somatomedin C) 1.3484
MCL1 myeloid cell leukemia 1 1.34314
PPARD peroxisome proliferator-activated receptor delta 1.30971
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.30819
ATF3 activating transcription factor 3 1.29905
CDK1 cyclin-dependent kinase 1 1.28241
RRM2 ribonucleotide reductase M2 1.27966
DNMT1 DNA (cytosine-5-)-methyltransferase 1 1.27966
F3 coagulation factor III (thromboplastin, tissue factor) 1.2596
COL4A4 collagen, type IV, alpha 4 1.25745
GADD45A growth arrest and DNA-damage-inducible, alpha 1.254
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.24997
C3 complement component 3 1.24812
COL1A2 collagen, type I, alpha 2 1.23743
IL13 interleukin 13 1.23042
PRC1 protein regulator of cytokinesis 1 1.22599
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 1.21043
BCL2 B-cell CLL/lymphoma 2 1.20526
MPO myeloperoxidase 1.20328
CTGF connective tissue growth factor 1.20031
DDIT3 DNA-damage-inducible transcript 3 1.19639
IL1B interleukin 1, beta 1.18783
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.17596
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.17366
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.17134
CCL2 chemokine (C-C motif) ligand 2 1.165
CXCL8 chemokine (C-X-C motif) ligand 8 1.16104
UBE2C ubiquitin-conjugating enzyme E2C 1.16035
CCNA2 cyclin A2 1.15223
AURKB aurora kinase B 1.15156
BCL2L1 BCL2-like 1 1.14678
IL10 interleukin 10 1.1403
S100A9 S100 calcium binding protein A9 1.13552
BBC3 BCL2 binding component 3 1.11639
CAT catalase 1.11639
ALB albumin 1.10977
SRXN1 sulfiredoxin 1 1.10246
CCNB2 cyclin B2 1.10069
PLN phospholamban 1.09436
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.09401
PHYH phytanoyl-CoA 2-hydroxylase 1.08868
SGK1 serum/glucocorticoid regulated kinase 1 1.08655
CALD1 caldesmon 1 1.08161
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.08091
PTGIS prostaglandin I2 (prostacyclin) synthase 1.07911
RB1 retinoblastoma 1 1.07804
BTG2 BTG family, member 2 1.07768
BTG3 BTG family, member 3 1.07625
FBLN1 fibulin 1 1.07057
SRM spermidine synthase 1.07022
TIMP2 TIMP metallopeptidase inhibitor 2 1.06844
APP amyloid beta (A4) precursor protein 1.06808
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 1.06808
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase 1.06588
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.06479
PARP1 poly (ADP-ribose) polymerase 1 1.06261
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 1.06225
EGR1 early growth response 1 1.06116
CP ceruloplasmin (ferroxidase) 1.05864
DUSP10 dual specificity phosphatase 10 1.05793
MVP major vault protein 1.05685
F2 coagulation factor II (thrombin) 1.05312
RFC3 replication factor C (activator 1) 3, 38kDa 1.05237
TYMS thymidylate synthetase 1.05089
RBL1 retinoblastoma-like 1 1.04721
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial 1.04684
IGFBP3 insulin-like growth factor binding protein 3 1.04538
PM20D2 peptidase M20 domain containing 2 1.04427
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.04389
DBP D site of albumin promoter (albumin D-box) binding protein 1.04239
TTK TTK protein kinase 1.04014
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.03976
MAPK3 mitogen-activated protein kinase 3 1.03567
MKI67 marker of proliferation Ki-67 1.02933
CDKN2A cyclin-dependent kinase inhibitor 2A 1.02746
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 1.02634
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 1.02447
CFD complement factor D (adipsin) 1.02373
ADA adenosine deaminase 1.02336
SESN1 sestrin 1 1.02225
ACHE acetylcholinesterase (Yt blood group) 1.02188
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 1.02151
TOP2A topoisomerase (DNA) II alpha 170kDa 1.02114
H2AFX H2A histone family, member X 1.02114
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.01928
MAPK8 mitogen-activated protein kinase 8 1.01512
CLU clusterin 1.01474
FASLG Fas ligand (TNF superfamily, member 6) 1.01286
CYP3A cytochrome P450, family 3, subfamily A 1.01249