Opioid-Related Disorders Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
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Genes

71 genes associated with the Opioid-Related Disorders phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ADRA1A adrenoceptor alpha 1A
ADRA2A adrenoceptor alpha 2A
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ANKK1 ankyrin repeat and kinase domain containing 1
ARRB2 arrestin, beta 2
BDNF brain-derived neurotrophic factor
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CNR1 cannabinoid receptor 1 (brain)
COMT catechol-O-methyltransferase
CRY1 cryptochrome circadian clock 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DLG4 discs, large homolog 4 (Drosophila)
DRD1 dopamine receptor D1
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
DRD4 dopamine receptor D4
GAL galanin/GMAP prepropeptide
GCH1 GTP cyclohydrolase 1
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRM6 glutamate receptor, metabotropic 6
GRM8 glutamate receptor, metabotropic 8
HINT1 histidine triad nucleotide binding protein 1
HOMER1 homer scaffolding protein 1
HRH1 histamine receptor H1
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
HTR3D 5-hydroxytryptamine (serotonin) receptor 3D, ionotropic
HTR3E 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic
IL1B interleukin 1, beta
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1
KCNG2 potassium channel, voltage gated modifier subfamily G, member 2
KPNA3 karyopherin alpha 3 (importin alpha 4)
MANEA mannosidase, endo-alpha
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MYOCD myocardin
NCAM1 neural cell adhesion molecule 1
NCK2 NCK adaptor protein 2
NGF nerve growth factor (beta polypeptide)
NR4A2 nuclear receptor subfamily 4, group A, member 2
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OPRD1 opioid receptor, delta 1
OPRK1 opioid receptor, kappa 1
OPRL1 opiate receptor-like 1
OPRM1 opioid receptor, mu 1
PDYN prodynorphin
PNOC prepronociceptin
POMC proopiomelanocortin
RGS17 regulator of G-protein signaling 17
RGS20 regulator of G-protein signaling 20
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TACR1 tachykinin receptor 1
TTC12 tetratricopeptide repeat domain 12
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7
WLS wntless Wnt ligand secretion mediator