Ofloxacin Gene Set

Dataset HMDB Metabolites of Enzymes
Category physical interactions
Type metabolite
Description An oxazinoquinolone carrying carboxy, fluoro, methyl and 4-methylpiperazino substituents. A synthetic fluoroquinolone antibacterial agent, it inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication. (Chemical Entities of Biological Interest Ontology, CHEBI_7731)
External Link http://www.hmdb.ca/metabolites/HMDB15296
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Genes

7 interacting proteins for the Ofloxacin metabolite from the curated HMDB Metabolites of Enzymes dataset.

Symbol Name
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC22A6 solute carrier family 22 (organic anion transporter), member 6
TOP2A topoisomerase (DNA) II alpha 170kDa