Ofloxacin Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description An oxazinoquinolone carrying carboxy, fluoro, methyl and 4-methylpiperazino substituents. A synthetic fluoroquinolone antibacterial agent, it inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication. (Chemical Entities of Biological Interest Ontology, CHEBI_7731)
External Link http://ctdbase.org/detail.go?type=chem&acc=D015242
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Genes

11 genes/proteins interacting with the chemical Ofloxacin from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
IL1B interleukin 1, beta
ITGB4 integrin, beta 4
PGD phosphogluconate dehydrogenase
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
UGT1A3 UDP glucuronosyltransferase 1 family, polypeptide A3
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7
UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9