Ocular Motility Disorders Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D015835
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Genes

262 genes/proteins associated with the disease Ocular Motility Disorders from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 2.20832
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 2.08248
FOS FBJ murine osteosarcoma viral oncogene homolog 2.02931
DRD2 dopamine receptor D2 2.01952
BDNF brain-derived neurotrophic factor 2.00371
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 1.91384
TNF tumor necrosis factor 1.8854
PRL prolactin 1.88159
JUN jun proto-oncogene 1.83025
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.82551
MAPK1 mitogen-activated protein kinase 1 1.80831
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.80623
IL6 interleukin 6 1.80472
EGR1 early growth response 1 1.77394
FAS Fas cell surface death receptor 1.77238
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.7623
DRD1 dopamine receptor D1 1.75915
MAPK3 mitogen-activated protein kinase 3 1.74842
TAGLN transgelin 1.72738
BCL2 B-cell CLL/lymphoma 2 1.71952
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.70285
BAX BCL2-associated X protein 1.69513
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.6677
GSK3B glycogen synthase kinase 3 beta 1.6636
C10ORF10 chromosome 10 open reading frame 10 1.65467
NUPR1 nuclear protein, transcriptional regulator, 1 1.64978
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 1.64461
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.61201
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 1.60314
GSTP1 glutathione S-transferase pi 1 1.58842
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 1.56459
CDK5 cyclin-dependent kinase 5 1.56361
CRH corticotropin releasing hormone 1.56288
INHBE inhibin, beta E 1.55921
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 1.55427
CAT catalase 1.54427
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.54208
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.54038
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.53724
MAPK8 mitogen-activated protein kinase 8 1.53603
GRIA2 glutamate receptor, ionotropic, AMPA 2 1.52212
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 1.50146
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 1.49864
FOSB FBJ murine osteosarcoma viral oncogene homolog B 1.49736
CCND1 cyclin D1 1.49711
MAPK14 mitogen-activated protein kinase 14 1.49407
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 1.48608
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.48042
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 1.46754
PENK proenkephalin 1.46383
TP53 tumor protein p53 1.46277
IFNG interferon, gamma 1.46198
JUNB jun B proto-oncogene 1.45857
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.45697
SCD stearoyl-CoA desaturase (delta-9-desaturase) 1.45089
FABP1 fatty acid binding protein 1, liver 1.44899
NOS2 nitric oxide synthase 2, inducible 1.4479
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.44653
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.44544
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.44355
CCND3 cyclin D3 1.43837
NPY neuropeptide Y 1.4313
DUSP1 dual specificity phosphatase 1 1.42804
TH tyrosine hydroxylase 1.41965
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.40815
UNG uracil-DNA glycosylase 1.40787
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 1.40568
BCL2L1 BCL2-like 1 1.40401
SOD1 superoxide dismutase 1, soluble 1.40204
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 1.39869
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 1.39869
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 1.39479
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 1.38724
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 1.38071
WIPI1 WD repeat domain, phosphoinositide interacting 1 1.38043
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 1.37418
GNAS GNAS complex locus 1.36791
RELN reelin 1.36019
NCL nucleolin 1.36019
NR0B2 nuclear receptor subfamily 0, group B, member 2 1.3556
GRIK2 glutamate receptor, ionotropic, kainate 2 1.35012
FSHB follicle stimulating hormone, beta polypeptide 1.34811
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.33938
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.33553
EPO erythropoietin 1.33052
CXCL8 chemokine (C-X-C motif) ligand 8 1.33022
RGS4 regulator of G-protein signaling 4 1.32074
PDIA4 protein disulfide isomerase family A, member 4 1.31237
GRIA1 glutamate receptor, ionotropic, AMPA 1 1.30971
VEGFA vascular endothelial growth factor A 1.30727
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 1.30696
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.30329
HSPB1 heat shock 27kDa protein 1 1.29719
POR P450 (cytochrome) oxidoreductase 1.29348
PDYN prodynorphin 1.28088
ICAM1 intercellular adhesion molecule 1 1.27966
IL1B interleukin 1, beta 1.27905
HMOX1 heme oxygenase 1 1.27409
ATF3 activating transcription factor 3 1.26298
TRIM2 tripartite motif containing 2 1.26083
MPO myeloperoxidase 1.25929
PDE4B phosphodiesterase 4B, cAMP-specific 1.25745
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 1.25494
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.25463
DDIT3 DNA-damage-inducible transcript 3 1.25059
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 1.24966
ALB albumin 1.24843
CAMK4 calcium/calmodulin-dependent protein kinase IV 1.2456
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.24528
SNAP25 synaptosomal-associated protein, 25kDa 1.23137
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 1.22821
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.22821
GUCY1B3 guanylate cyclase 1, soluble, beta 3 1.22758
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 1.21759
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 1.21435
CSNK2A1 casein kinase 2, alpha 1 polypeptide 1.21402
CES2 carboxylesterase 2 1.20881
CALR calreticulin 1.2013
GJA1 gap junction protein, alpha 1, 43kDa 1.199
SREBF2 sterol regulatory element binding transcription factor 2 1.19835
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 1.19737
RGS2 regulator of G-protein signaling 2 1.19737
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 1.19737
KLHL7 kelch-like family member 7 1.19672
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 1.19213
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 1.19179
FMOD fibromodulin 1.19146
SEPT4 septin 4 1.19113
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.18652
FNDC4 fibronectin type III domain containing 4 1.1862
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 1.18554
GRIK5 glutamate receptor, ionotropic, kainate 5 1.18554
PARP1 poly (ADP-ribose) polymerase 1 1.18554
ODC1 ornithine decarboxylase 1 1.18059
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 1.17993
MAP2K2 mitogen-activated protein kinase kinase 2 1.17728
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 1.17596
PER1 period circadian clock 1 1.17431
RRM2 ribonucleotide reductase M2 1.17235
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.17168
TAC1 tachykinin, precursor 1 1.17
NPTX2 neuronal pentraxin II 1.169
CXCL10 chemokine (C-X-C motif) ligand 10 1.16401
LHB luteinizing hormone beta polypeptide 1.16401
NPAS2 neuronal PAS domain protein 2 1.16335
OPRM1 opioid receptor, mu 1 1.16035
HSPA1B heat shock 70kDa protein 1B 1.16035
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4 1.15865
ITPKA inositol-trisphosphate 3-kinase A 1.15831
ANXA4 annexin A4 1.15763
STBD1 starch binding domain 1 1.15357
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase 1.15324
ARC activity-regulated cytoskeleton-associated protein 1.15256
CNR1 cannabinoid receptor 1 (brain) 1.15223
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 1.14954
UGDH UDP-glucose 6-dehydrogenase 1.14713
AKT2 v-akt murine thymoma viral oncogene homolog 2 1.14713
NR1I3 nuclear receptor subfamily 1, group I, member 3 1.1461
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 1.14473
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.14404
GABRD gamma-aminobutyric acid (GABA) A receptor, delta 1.14404
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 1.13963
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 1.13621
MSH2 mutS homolog 2 1.12737
BAG3 BCL2-associated athanogene 3 1.12737
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 1.12737
GAP43 growth associated protein 43 1.1253
EFNB1 ephrin-B1 1.12082
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 1.12014
INS insulin 1.11877
CREB1 cAMP responsive element binding protein 1 1.11877
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.11809
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.11673
GPX1 glutathione peroxidase 1 1.11673
CP ceruloplasmin (ferroxidase) 1.11536
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 1.11255
GFAP glial fibrillary acidic protein 1.11081
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 1.10872
ACHE acetylcholinesterase (Yt blood group) 1.10872
TYMS thymidylate synthetase 1.10527
NR4A1 nuclear receptor subfamily 4, group A, member 1 1.10246
NCAN neurocan 1.10104
GSK3A glycogen synthase kinase 3 alpha 1.10069
CDC6 cell division cycle 6 1.09786
CALM2 calmodulin 2 (phosphorylase kinase, delta) 1.09646
HRH1 histamine receptor H1 1.09401
DLAT dihydrolipoamide S-acetyltransferase 1.09262
HIGD1A HIG1 hypoxia inducible domain family, member 1A 1.09262
NRP1 neuropilin 1 1.09119
MSMO1 methylsterol monooxygenase 1 1.09119
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 1.0894
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 1.08513
EFNA2 ephrin-A2 1.08337
MBP myelin basic protein 1.08091
NGF nerve growth factor (beta polypeptide) 1.07947
SOD2 superoxide dismutase 2, mitochondrial 1.07947
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2 1.0784
MKI67 marker of proliferation Ki-67 1.07804
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 1.07768
PDLIM7 PDZ and LIM domain 7 (enigma) 1.07732
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.07625
HSPA8 heat shock 70kDa protein 8 1.07553
NR4A2 nuclear receptor subfamily 4, group A, member 2 1.07482
CTSL cathepsin L 1.07269
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 1.07128
TPM1 tropomyosin 1 (alpha) 1.07093
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 1.06917
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 1.06771
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 1.06698
DHFR dihydrofolate reductase 1.06698
EGR2 early growth response 2 1.06479
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 1.06333
KLF6 Kruppel-like factor 6 1.06297
TOB1 transducer of ERBB2, 1 1.05972
IL10 interleukin 10 1.059
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.059
FGF2 fibroblast growth factor 2 (basic) 1.05793
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit 1.05312
MCL1 myeloid cell leukemia 1 1.05274
TEX261 testis expressed 261 1.052
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic 1.05052
GSTM1 glutathione S-transferase mu 1 1.04868
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 1.04794
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.04794
MALAT1 metastasis associated lung adenocarcinoma transcript 1 (non-protein coding) 1.04684
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 1.04611
SYT2 synaptotagmin II 1.04427
PRKCE protein kinase C, epsilon 1.04427
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C 1.04389
GEM GTP binding protein overexpressed in skeletal muscle 1.04314
PKM pyruvate kinase, muscle 1.04239
ARNTL aryl hydrocarbon receptor nuclear translocator-like 1.04014
APAF1 apoptotic peptidase activating factor 1 1.03864
OSBPL8 oxysterol binding protein-like 8 1.03752
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.03678
HOMER1 homer scaffolding protein 1 1.03456
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 1.03419
GRIA3 glutamate receptor, ionotropic, AMPA 3 1.03382
RFC3 replication factor C (activator 1) 3, 38kDa 1.03382
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.03345
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.03271
ANXA5 annexin A5 1.03159
PBX3 pre-B-cell leukemia homeobox 3 1.03046
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial 1.02783
IL2 interleukin 2 1.02522
ADCY8 adenylate cyclase 8 (brain) 1.02485
KLHL24 kelch-like family member 24 1.02485
PRPF38B pre-mRNA processing factor 38B 1.02447
CFLAR CASP8 and FADD-like apoptosis regulator 1.02262
CCNE1 cyclin E1 1.02225
ANGPTL4 angiopoietin-like 4 1.02114
TRH thyrotropin-releasing hormone 1.02003
ECT2 epithelial cell transforming 2 1.0189
EFNB3 ephrin-B3 1.01814
KIFAP3 kinesin-associated protein 3 1.01776
CCNB2 cyclin B2 1.01776
CCNA2 cyclin A2 1.01324
AP2B1 adaptor-related protein complex 2, beta 1 subunit 1.01324
PPP1R15A protein phosphatase 1, regulatory subunit 15A 1.01286
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 1.01212
LARGE like-glycosyltransferase 1.01174
MAGED1 melanoma antigen family D1 1.01137