Occupational Diseases Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D009784
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Genes

268 genes/proteins associated with the disease Occupational Diseases from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 2.88009
PON1 paraoxonase 1 2.88009
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 2.88009
ERCC2 excision repair cross-complementation group 2 2.88009
NQO1 NAD(P)H dehydrogenase, quinone 1 2.88009
ALB albumin 2.88009
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1 2.88009
MPO myeloperoxidase 2.88009
CAT catalase 1.96358
GSTM1 glutathione S-transferase mu 1 1.86045
HMOX1 heme oxygenase 1 1.84215
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.79503
TXNRD1 thioredoxin reductase 1 1.7872
TP53 tumor protein p53 1.77413
FOS FBJ murine osteosarcoma viral oncogene homolog 1.76366
CXCL8 chemokine (C-X-C motif) ligand 8 1.75182
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.69448
IL1B interleukin 1, beta 1.68825
CCL2 chemokine (C-C motif) ligand 2 1.68041
GSTT1 glutathione S-transferase theta 1 1.68019
HSPA8 heat shock 70kDa protein 8 1.67094
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.65511
DDIT3 DNA-damage-inducible transcript 3 1.65336
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.65314
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.63966
IFNG interferon, gamma 1.62915
HSPA1A heat shock 70kDa protein 1A 1.6278
CTH cystathionine gamma-lyase 1.60897
NOS2 nitric oxide synthase 2, inducible 1.60781
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 1.59943
FAS Fas cell surface death receptor 1.58678
IL6 interleukin 6 1.57688
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.57688
IL4 interleukin 4 1.54402
TNF tumor necrosis factor 1.54184
GADD45A growth arrest and DNA-damage-inducible, alpha 1.53579
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.53209
GSR glutathione reductase 1.53061
GSS glutathione synthetase 1.50473
MAPK1 mitogen-activated protein kinase 1 1.50018
GCLM glutamate-cysteine ligase, modifier subunit 1.49736
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.4966
JUN jun proto-oncogene 1.49356
FN1 fibronectin 1 1.48864
CCND1 cyclin D1 1.48864
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 1.4817
ICAM1 intercellular adhesion molecule 1 1.47787
F5 coagulation factor V (proaccelerin, labile factor) 1.46041
BAX BCL2-associated X protein 1.43782
ACO1 aconitase 1, soluble 1.4275
CALM1 calmodulin 1 (phosphorylase kinase, delta) 1.42481
DUSP1 dual specificity phosphatase 1 1.42183
FASN fatty acid synthase 1.41341
HMBS hydroxymethylbilane synthase 1.40541
GSTM3 glutathione S-transferase mu 3 (brain) 1.40232
IHH indian hedgehog 1.39757
SOD1 superoxide dismutase 1, soluble 1.39422
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 1.39114
IL10 interleukin 10 1.38752
SQSTM1 sequestosome 1 1.38498
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 1.37902
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.37303
PVR poliovirus receptor 1.36876
NFE2L2 nuclear factor, erythroid 2-like 2 1.36476
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.35849
GPX1 glutathione peroxidase 1 1.35763
SQLE squalene epoxidase 1.35415
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 1.34811
NOS3 nitric oxide synthase 3 (endothelial cell) 1.34082
VNN1 vanin 1 1.33642
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 1.33434
GLUL glutamate-ammonia ligase 1.33052
GDF15 growth differentiation factor 15 1.32846
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 1.32846
MVD mevalonate (diphospho) decarboxylase 1.31867
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 1.31387
CCNG1 cyclin G1 1.31387
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.31327
ACSL1 acyl-CoA synthetase long-chain family member 1 1.3103
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.30482
LHB luteinizing hormone beta polypeptide 1.2861
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) 1.28579
PARP1 poly (ADP-ribose) polymerase 1 1.28272
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 1.28088
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit 1.28088
GTF3A general transcription factor IIIA 1.28058
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 1.27347
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4 1.27347
EGR1 early growth response 1 1.27193
ACTB actin, beta 1.26947
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 1.26947
ACO2 aconitase 2, mitochondrial 1.26856
EIF3B eukaryotic translation initiation factor 3, subunit B 1.26856
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6 1.26794
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 1.26607
IL2 interleukin 2 1.26359
HBB hemoglobin, beta 1.24781
MMP9 matrix metallopeptidase 9 1.24338
HDAC8 histone deacetylase 8 1.23993
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa 1.23265
PPARG peroxisome proliferator-activated receptor gamma 1.23042
FDXR ferredoxin reductase 1.23042
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha 1.23011
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 1.22821
MMP2 matrix metallopeptidase 2 1.22696
BIRC3 baculoviral IAP repeat containing 3 1.22664
WDR36 WD repeat domain 36 1.22534
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.22501
PDIA3 protein disulfide isomerase family A, member 3 1.22177
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.22145
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.21951
BLCAP bladder cancer associated protein 1.21855
CXCL2 chemokine (C-X-C motif) ligand 2 1.21663
CSNK2A1 casein kinase 2, alpha 1 polypeptide 1.20946
NFIX nuclear factor I/X (CCAAT-binding transcription factor) 1.20622
ZSWIM3 zinc finger, SWIM-type containing 3 1.20558
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 1.20558
AHR aryl hydrocarbon receptor 1.20031
LTB lymphotoxin beta (TNF superfamily, member 3) 1.19672
BCL2 B-cell CLL/lymphoma 2 1.19639
CALR calreticulin 1.19574
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G 1.19312
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.19312
VEGFA vascular endothelial growth factor A 1.19279
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 1.19213
OGG1 8-oxoguanine DNA glycosylase 1.19213
NFIB nuclear factor I/B 1.19047
CLU clusterin 1.19047
IPO4 importin 4 1.18718
ECI1 enoyl-CoA delta isomerase 1 1.18424
SREBF1 sterol regulatory element binding transcription factor 1 1.18293
BSPRY B-box and SPRY domain containing 1.17596
ODC1 ornithine decarboxylase 1 1.17431
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 1.17034
GSTP1 glutathione S-transferase pi 1 1.16866
CYCS cytochrome c, somatic 1.16733
ANGPTL4 angiopoietin-like 4 1.167
PIR pirin (iron-binding nuclear protein) 1.167
DNMT1 DNA (cytosine-5-)-methyltransferase 1 1.16666
SRXN1 sulfiredoxin 1 1.165
PPID peptidylprolyl isomerase D 1.16467
HSPB1 heat shock 27kDa protein 1 1.16269
GCLC glutamate-cysteine ligase, catalytic subunit 1.15899
STIP1 stress-induced phosphoprotein 1 1.1529
PRKCZ protein kinase C, zeta 1.15022
BCL6 B-cell CLL/lymphoma 6 1.15022
S100A10 S100 calcium binding protein A10 1.15022
ALDH1L2 aldehyde dehydrogenase 1 family, member L2 1.14954
IL1A interleukin 1, alpha 1.14781
MAPK9 mitogen-activated protein kinase 9 1.14747
CCL3 chemokine (C-C motif) ligand 3 1.14541
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 1.14507
SGK1 serum/glucocorticoid regulated kinase 1 1.14473
CAPN2 calpain 2, (m/II) large subunit 1.14268
TPM3 tropomyosin 3 1.13997
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 1.13963
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.13929
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 1.13758
RPL10A ribosomal protein L10a 1.13484
HAVCR1 hepatitis A virus cellular receptor 1 1.13484
BHMT betaine--homocysteine S-methyltransferase 1.13484
RHBG Rh family, B glycoprotein (gene/pseudogene) 1.13075
SESN2 sestrin 2 1.13007
PDK1 pyruvate dehydrogenase kinase, isozyme 1 1.12254
DHODH dihydroorotate dehydrogenase (quinone) 1.12117
PLD1 phospholipase D1, phosphatidylcholine-specific 1.11775
PELI1 pellino E3 ubiquitin protein ligase 1 1.11741
RCAN2 regulator of calcineurin 2 1.11707
MYT1L myelin transcription factor 1-like 1.11639
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 1.11396
TGFB1 transforming growth factor, beta 1 1.11325
ATPIF1 ATPase inhibitory factor 1 1.1129
SET SET nuclear proto-oncogene 1.11255
AR androgen receptor 1.11081
CD86 CD86 molecule 1.10838
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase 1.10838
RABGGTA Rab geranylgeranyltransferase, alpha subunit 1.10631
GCK glucokinase (hexokinase 4) 1.10631
IL13 interleukin 13 1.10527
MT1A metallothionein 1A 1.09541
G0S2 G0/G1 switch 2 1.09506
APLP2 amyloid beta (A4) precursor-like protein 2 1.09226
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) 1.09083
CCL4 chemokine (C-C motif) ligand 4 1.08975
IVD isovaleryl-CoA dehydrogenase 1.08833
SPP1 secreted phosphoprotein 1 1.08726
PRDX6 peroxiredoxin 6 1.08655
LMNA lamin A/C 1.08407
FDPS farnesyl diphosphate synthase 1.08407
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain 1.08231
RGS3 regulator of G-protein signaling 3 1.08126
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.08091
PDE4D phosphodiesterase 4D, cAMP-specific 1.08055
GSTA3 glutathione S-transferase alpha 3 1.07911
PGK1 phosphoglycerate kinase 1 1.07804
GBE1 glucan (1,4-alpha-), branching enzyme 1 1.07732
RHOB ras homolog family member B 1.07589
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase 1.0734
SOD2 superoxide dismutase 2, mitochondrial 1.07128
USP18 ubiquitin specific peptidase 18 1.07022
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 1.07022
NR4A2 nuclear receptor subfamily 4, group A, member 2 1.06987
OAT ornithine aminotransferase 1.06771
SRSF2 serine/arginine-rich splicing factor 2 1.06661
MTF1 metal-regulatory transcription factor 1 1.06625
RRAGA Ras-related GTP binding A 1.06442
RREB1 ras responsive element binding protein 1 1.06406
HGH1 HGH1 homolog (S. cerevisiae) 1.0637
HDAC10 histone deacetylase 10 1.0637
IL5 interleukin 5 1.06225
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma 1.05936
NR0B2 nuclear receptor subfamily 0, group B, member 2 1.05828
PRNP prion protein 1.0561
MRPL24 mitochondrial ribosomal protein L24 1.0561
ACSL5 acyl-CoA synthetase long-chain family member 5 1.0561
MRPL1 mitochondrial ribosomal protein L1 1.05573
USP47 ubiquitin specific peptidase 47 1.05498
ISG20 interferon stimulated exonuclease gene 20kDa 1.05274
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase 1.05237
AHCY adenosylhomocysteinase 1.052
MAPK3 mitogen-activated protein kinase 3 1.05015
TSGA10 testis specific, 10 1.04941
TCP1 t-complex 1 1.04904
SOS2 son of sevenless homolog 2 (Drosophila) 1.04794
KIF3B kinesin family member 3B 1.04794
MCL1 myeloid cell leukemia 1 1.04684
HSPH1 heat shock 105kDa/110kDa protein 1 1.04276
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 1.04126
FBXO3 F-box protein 3 1.04088
EED embryonic ectoderm development 1.04051
CPNE3 copine III 1.04014
EXOC3 exocyst complex component 3 1.04014
SLC39A8 solute carrier family 39 (zinc transporter), member 8 1.03939
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.03901
CASP6 caspase 6, apoptosis-related cysteine peptidase 1.03901
PRKCE protein kinase C, epsilon 1.03901
TBCB tubulin folding cofactor B 1.03752
MAOB monoamine oxidase B 1.03715
PKM pyruvate kinase, muscle 1.03715
SLC39A14 solute carrier family 39 (zinc transporter), member 14 1.03641
LRRC59 leucine rich repeat containing 59 1.03419
FTSJ1 FtsJ RNA methyltransferase homolog 1 (E. coli) 1.03382
VARS2 valyl-tRNA synthetase 2, mitochondrial 1.03382
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 1.03345
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 1.03308
STX12 syntaxin 12 1.03308
CD47 CD47 molecule 1.03308
BBC3 BCL2 binding component 3 1.03197
ANXA2 annexin A2 1.03159
RUNX1 runt-related transcription factor 1 1.03046
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 1.03009
SART1 squamous cell carcinoma antigen recognized by T cells 1.02708
TPD52L2 tumor protein D52-like 2 1.02671
DDAH1 dimethylarginine dimethylaminohydrolase 1 1.02373
XPA xeroderma pigmentosum, complementation group A 1.02373
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 1.02373
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 1.02336
GALK2 galactokinase 2 1.02151
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 1.02114
KEAP1 kelch-like ECH-associated protein 1 1.02114
PF4 platelet factor 4 1.02077
PHLDA3 pleckstrin homology-like domain, family A, member 3 1.02077
MTF2 metal response element binding transcription factor 2 1.02003
TXN thioredoxin 1.01966
TRIB1 tribbles pseudokinase 1 1.01739
HLA-DMB major histocompatibility complex, class II, DM beta 1.01587
CCNB2 cyclin B2 1.01249
CIRBP cold inducible RNA binding protein 1.01212