Obsessive-Compulsive Disorder Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description An anxiety disorder that involves unwanted and repeated thoughts, feelings, ideas, sensations (obsessions), or behaviors that make them feel driven to do something (compulsions). (Human Disease Ontology, DOID_10933)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D009771
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Genes

84 genes/proteins associated with the disease Obsessive-Compulsive Disorder from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled 2.88009
HOXB8 homeobox B8 2.88009
SLITRK5 SLIT and NTRK-like family, member 5 2.88009
CCKBR cholecystokinin B receptor 2.88009
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 2.88009
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 2.88009
BDNF brain-derived neurotrophic factor 2.88009
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 2.22509
PRL prolactin 2.13825
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 2.0754
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 2.02224
DRD2 dopamine receptor D2 1.945
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 1.87708
CAT catalase 1.76927
FOS FBJ murine osteosarcoma viral oncogene homolog 1.76366
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 1.74761
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.74039
TH tyrosine hydroxylase 1.72509
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 1.64326
ARC activity-regulated cytoskeleton-associated protein 1.57281
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.52187
EGR1 early growth response 1 1.48967
POMC proopiomelanocortin 1.46674
MAOB monoamine oxidase B 1.4583
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.44572
NPY neuropeptide Y 1.42562
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.42535
INHA inhibin, alpha 1.41721
SOD1 superoxide dismutase 1, soluble 1.39422
DRD3 dopamine receptor D3 1.38641
TNF tumor necrosis factor 1.38641
BCL2 B-cell CLL/lymphoma 2 1.38441
HOMER1 homer scaffolding protein 1 1.3556
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.35242
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.3414
MAPK1 mitogen-activated protein kinase 1 1.32816
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3 1.32458
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6 1.31956
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 1.29379
DRD1 dopamine receptor D1 1.29256
NUPR1 nuclear protein, transcriptional regulator, 1 1.28425
CDK5 cyclin-dependent kinase 5 1.26052
COMT catechol-O-methyltransferase 1.22664
FOSB FBJ murine osteosarcoma viral oncogene homolog B 1.22177
GRIA2 glutamate receptor, ionotropic, AMPA 2 1.21984
VEGFA vascular endothelial growth factor A 1.19279
JUN jun proto-oncogene 1.19213
PENK proenkephalin 1.18849
FNDC4 fibronectin type III domain containing 4 1.18193
SYP synaptophysin 1.17563
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 1.17034
CRH corticotropin releasing hormone 1.16866
RGS4 regulator of G-protein signaling 4 1.16137
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5 1.1607
MAP2 microtubule-associated protein 2 1.15055
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 1.15022
BAX BCL2-associated X protein 1.14989
CNR1 cannabinoid receptor 1 (brain) 1.14678
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.14644
IL6 interleukin 6 1.13586
GDNF glial cell derived neurotrophic factor 1.13484
INHBE inhibin, beta E 1.13007
CREB1 cAMP responsive element binding protein 1 1.1122
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 1.09998
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.08091
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 1.07411
TAGLN transgelin 1.07199
CAMK4 calcium/calmodulin-dependent protein kinase IV 1.07022
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 1.06406
DRD4 dopamine receptor D4 1.06333
EGR2 early growth response 2 1.06008
NR0B2 nuclear receptor subfamily 0, group B, member 2 1.05828
C10ORF10 chromosome 10 open reading frame 10 1.05349
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 1.05349
GSTP1 glutathione S-transferase pi 1 1.05089
MAPK3 mitogen-activated protein kinase 3 1.05015
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled 1.04647
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 1.04088
DUSP1 dual specificity phosphatase 1 1.03604
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 1.03345
GRIA3 glutamate receptor, ionotropic, AMPA 3 1.03046
FAS Fas cell surface death receptor 1.02485
FABP1 fatty acid binding protein 1, liver 1.02299
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.01814