Obesity Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description OMIM mapping confirmed by DO. [SN]. (Human Disease Ontology, DOID_9970)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D009765
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Genes

654 genes/proteins associated with the disease Obesity from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
APOE apolipoprotein E 2.88009
LEPR leptin receptor 2.88009
MIR34A microRNA 34a 2.88009
TNF tumor necrosis factor 2.88009
AQP7 aquaporin 7 2.88009
CASP1 caspase 1, apoptosis-related cysteine peptidase 2.88009
AKT1 v-akt murine thymoma viral oncogene homolog 1 2.88009
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 2.88009
FTO fat mass and obesity associated 2.88009
ADIPOQ adiponectin, C1Q and collagen domain containing 2.88009
PACS1 phosphofurin acidic cluster sorting protein 1 2.88009
ATPAF1 ATP synthase mitochondrial F1 complex assembly factor 1 2.88009
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 2.88009
LBP lipopolysaccharide binding protein 2.88009
CTF1 cardiotrophin 1 2.88009
NPY5R neuropeptide Y receptor Y5 2.88009
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 2.88009
DPYD dihydropyrimidine dehydrogenase 2.88009
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7 2.88009
GHRL ghrelin/obestatin prepropeptide 2.88009
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 2.88009
UCP3 uncoupling protein 3 (mitochondrial, proton carrier) 2.88009
ADRB2 adrenoceptor beta 2, surface 2.88009
MIR184 microRNA 184 2.88009
NEGR1 neuronal growth regulator 1 2.88009
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit 2.88009
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 2.88009
UQCRC2 ubiquinol-cytochrome c reductase core protein II 2.88009
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 2.88009
AKAP1 A kinase (PRKA) anchor protein 1 2.88009
SOD2 superoxide dismutase 2, mitochondrial 2.88009
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic 2.88009
CES1 carboxylesterase 1 2.88009
FASN fatty acid synthase 2.88009
FGF21 fibroblast growth factor 21 2.88009
KITLG KIT ligand 2.88009
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta 2.88009
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 2.88009
PLIN1 perilipin 1 2.88009
AKR1C3 aldo-keto reductase family 1, member C3 2.88009
MC4R melanocortin 4 receptor 2.88009
PPARG peroxisome proliferator-activated receptor gamma 2.88009
SCD stearoyl-CoA desaturase (delta-9-desaturase) 2.88009
FOXO3 forkhead box O3 2.88009
PPARA peroxisome proliferator-activated receptor alpha 2.88009
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 2.88009
HMGB2 high mobility group box 2 2.88009
SDC3 syndecan 3 2.88009
LEP leptin 2.88009
MMP9 matrix metallopeptidase 9 2.88009
GH1 growth hormone 1 2.88009
ASIP agouti signaling protein 2.88009
ALDH6A1 aldehyde dehydrogenase 6 family, member A1 2.88009
PMCH pro-melanin-concentrating hormone 2.88009
VLDLR very low density lipoprotein receptor 2.88009
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 2.88009
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 2.88009
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial 2.88009
LACTB lactamase, beta 2.88009
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa 2.88009
RMST rhabdomyosarcoma 2 associated transcript (non-protein coding) 2.88009
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3 2.88009
LPL lipoprotein lipase 2.88009
PARP1 poly (ADP-ribose) polymerase 1 2.88009
ICAM1 intercellular adhesion molecule 1 2.88009
MUT methylmalonyl CoA mutase 2.88009
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain 2.88009
HOXB5 homeobox B5 2.88009
GNAS GNAS complex locus 2.88009
TFRC transferrin receptor 2.88009
IRS1 insulin receptor substrate 1 2.88009
CA3 carbonic anhydrase III 2.88009
CPE carboxypeptidase E 2.88009
TRPV1 transient receptor potential cation channel, subfamily V, member 1 2.88009
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 2.88009
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 2.88009
SIRT3 sirtuin 3 2.88009
SIRT1 sirtuin 1 2.88009
CARTPT CART prepropeptide 2.88009
ALDH1L1 aldehyde dehydrogenase 1 family, member L1 2.88009
GFPT1 glutamine--fructose-6-phosphate transaminase 1 2.88009
INS insulin 2.88009
F2 coagulation factor II (thrombin) 2.88009
AGRP agouti related neuropeptide 2.88009
CPB2 carboxypeptidase B2 (plasma) 2.88009
ACLY ATP citrate lyase 2.88009
BCHE butyrylcholinesterase 2.88009
HMOX1 heme oxygenase 1 2.88009
SREBF1 sterol regulatory element binding transcription factor 1 2.88009
CIDEA cell death-inducing DFFA-like effector a 2.88009
NQO1 NAD(P)H dehydrogenase, quinone 1 2.88009
RAI1 retinoic acid induced 1 2.88009
HADH hydroxyacyl-CoA dehydrogenase 2.88009
GNPDA2 glucosamine-6-phosphate deaminase 2 2.88009
ADRB3 adrenoceptor beta 3 2.88009
ESR1 estrogen receptor 1 2.88009
BMIQ7 Obesity, susceptibility to, on chromosome 4 2.88009
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 2.88009
BMIQ8 body mass index quantitative trait locus 8 2.88009
SAT1 spermidine/spermine N1-acetyltransferase 1 2.88009
ACSL1 acyl-CoA synthetase long-chain family member 1 2.88009
TF transferrin 2.88009
PCSK1 proprotein convertase subtilisin/kexin type 1 2.88009
MC3R melanocortin 3 receptor 2.88009
ACACB acetyl-CoA carboxylase beta 2.88009
CNR1 cannabinoid receptor 1 (brain) 2.88009
IL6 interleukin 6 2.88009
BMIQ10 Obesity, susceptibility to, on chromosome 10q 2.88009
PRKCH protein kinase C, eta 2.88009
MTCH2 mitochondrial carrier 2 2.88009
GLUL glutamate-ammonia ligase 2.88009
AFF4 AF4/FMR2 family, member 4 2.88009
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 2.88009
KCTD15 potassium channel tetramerization domain containing 15 2.88009
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 2.88009
GPX1 glutathione peroxidase 1 2.88009
CYCS cytochrome c, somatic 2.88009
DCXR dicarbonyl/L-xylulose reductase 2.88009
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 2.88009
CS citrate synthase 2.88009
PPM1L protein phosphatase, Mg2+/Mn2+ dependent, 1L 2.88009
FTL ferritin, light polypeptide 2.88009
GCG glucagon 2.88009
CYB5A cytochrome b5 type A (microsomal) 2.88009
SH2B1 SH2B adaptor protein 1 2.88009
NR0B2 nuclear receptor subfamily 0, group B, member 2 2.88009
ADRB1 adrenoceptor beta 1 2.88009
PYY peptide YY 2.88009
CTSS cathepsin S 2.88009
NEIL1 nei endonuclease VIII-like 1 (E. coli) 2.88009
NAMPT nicotinamide phosphoribosyltransferase 2.88009
GPX3 glutathione peroxidase 3 2.88009
GAS7 growth arrest-specific 7 2.88009
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 2.88009
EFNB1 ephrin-B1 2.88009
NHLH2 nescient helix loop helix 2 2.88009
ETFDH electron-transferring-flavoprotein dehydrogenase 2.88009
POMC proopiomelanocortin 2.88009
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 2.88009
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 2.88009
FAAH fatty acid amide hydrolase 2.88009
NR1I3 nuclear receptor subfamily 1, group I, member 3 2.88009
NPY1R neuropeptide Y receptor Y1 2.88009
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 2.88009
PPARD peroxisome proliferator-activated receptor delta 2.88009
COX7C cytochrome c oxidase subunit VIIc 2.88009
NPC1 Niemann-Pick disease, type C1 2.88009
NR1I2 nuclear receptor subfamily 1, group I, member 2 2.88009
STS steroid sulfatase (microsomal), isozyme S 2.88009
HK2 hexokinase 2 2.88009
ACP5 acid phosphatase 5, tartrate resistant 2.88009
IGF2 insulin-like growth factor 2 2.88009
SIM1 single-minded family bHLH transcription factor 1 2.88009
TMEM18 transmembrane protein 18 2.88009
MIR21 microRNA 21 2.88009
CAT catalase 2.17766
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 2.11933
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 2.08248
SOD1 superoxide dismutase 1, soluble 2.07612
GSK3B glycogen synthase kinase 3 beta 2.04411
FOS FBJ murine osteosarcoma viral oncogene homolog 2.01979
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 2.01322
TGFB1 transforming growth factor, beta 1 1.99679
VCAM1 vascular cell adhesion molecule 1 1.99018
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 1.98974
ACACA acetyl-CoA carboxylase alpha 1.98755
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 1.96239
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.96086
NOS2 nitric oxide synthase 2, inducible 1.94516
INSR insulin receptor 1.94469
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.93782
IGF1 insulin-like growth factor 1 (somatomedin C) 1.92548
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.91451
BCL2 B-cell CLL/lymphoma 2 1.90607
CCND1 cyclin D1 1.90492
MAPK8 mitogen-activated protein kinase 8 1.87059
VEGFA vascular endothelial growth factor A 1.86991
CCL2 chemokine (C-C motif) ligand 2 1.85221
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.85011
TH tyrosine hydroxylase 1.84001
MAPK3 mitogen-activated protein kinase 3 1.83788
IL1B interleukin 1, beta 1.83343
MAPK1 mitogen-activated protein kinase 1 1.82341
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.80435
ALB albumin 1.79942
ACOX1 acyl-CoA oxidase 1, palmitoyl 1.7853
SPP1 secreted phosphoprotein 1 1.78454
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 1.77782
MAPK9 mitogen-activated protein kinase 9 1.7552
EGR1 early growth response 1 1.74984
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.73738
CPT1A carnitine palmitoyltransferase 1A (liver) 1.73719
BAX BCL2-associated X protein 1.73679
JUN jun proto-oncogene 1.72613
NFE2L2 nuclear factor, erythroid 2-like 2 1.72467
FSHB follicle stimulating hormone, beta polypeptide 1.72343
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.71993
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.71503
NPY neuropeptide Y 1.7074
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 1.70574
FASLG Fas ligand (TNF superfamily, member 6) 1.68633
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.6857
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.68084
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.67333
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.67224
LDLR low density lipoprotein receptor 1.67137
CDK2 cyclin-dependent kinase 2 1.66964
IFNG interferon, gamma 1.6621
GSR glutathione reductase 1.66038
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.65731
CRP C-reactive protein, pentraxin-related 1.65489
FABP4 fatty acid binding protein 4, adipocyte 1.65445
CDK4 cyclin-dependent kinase 4 1.65314
DDIT3 DNA-damage-inducible transcript 3 1.64752
BDNF brain-derived neurotrophic factor 1.64506
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 1.64056
CREB1 cAMP responsive element binding protein 1 1.63698
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.63653
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 1.62983
FAS Fas cell surface death receptor 1.62803
TP53 tumor protein p53 1.61736
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 1.61014
EDN1 endothelin 1 1.60851
BCL2L1 BCL2-like 1 1.60501
DUSP1 dual specificity phosphatase 1 1.59404
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.58889
HSPE1 heat shock 10kDa protein 1 1.58607
PNPLA2 patatin-like phospholipase domain containing 2 1.58514
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 1.57641
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.56947
ERN1 endoplasmic reticulum to nucleus signaling 1 1.56828
CD36 CD36 molecule (thrombospondin receptor) 1.56558
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.56361
IL4 interleukin 4 1.55946
BAD BCL2-associated agonist of cell death 1.55946
G6PD glucose-6-phosphate dehydrogenase 1.55946
MMP2 matrix metallopeptidase 2 1.55946
TLR4 toll-like receptor 4 1.5555
PRL prolactin 1.54669
COL1A1 collagen, type I, alpha 1 1.54596
MMP13 matrix metallopeptidase 13 1.53308
TTR transthyretin 1.53061
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 1.52865
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 1.52791
FOXO1 forkhead box O1 1.52187
STAR steroidogenic acute regulatory protein 1.52061
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.51607
PRKCA protein kinase C, alpha 1.51607
NOX4 NADPH oxidase 4 1.51155
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.5108
CYBA cytochrome b-245, alpha polypeptide 1.50776
ACADVL acyl-CoA dehydrogenase, very long chain 1.50675
MMP7 matrix metallopeptidase 7 1.50675
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.50146
NOS3 nitric oxide synthase 3 (endothelial cell) 1.49736
LIPE lipase, hormone-sensitive 1.49711
RELN reelin 1.49226
FOSL1 FOS-like antigen 1 1.49174
ACTA2 actin, alpha 2, smooth muscle, aorta 1.48736
H2AFX H2A histone family, member X 1.48479
IL5 interleukin 5 1.48479
CCNB1 cyclin B1 1.47991
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 1.47582
ADIPOR2 adiponectin receptor 2 1.47348
IL10 interleukin 10 1.46701
GSTA4 glutathione S-transferase alpha 4 1.46674
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 1.46225
AHR aryl hydrocarbon receptor 1.45936
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.4591
HDAC2 histone deacetylase 2 1.45564
JUND jun D proto-oncogene 1.45484
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 1.45405
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.45326
RXRA retinoid X receptor, alpha 1.45115
APOC3 apolipoprotein C-III 1.45089
ATF3 activating transcription factor 3 1.45063
APP amyloid beta (A4) precursor protein 1.44599
XBP1 X-box binding protein 1 1.44436
ENO1 enolase 1, (alpha) 1.44436
GCLC glutamate-cysteine ligase, catalytic subunit 1.44056
IGFBP1 insulin-like growth factor binding protein 1 1.43673
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.43591
SP1 Sp1 transcription factor 1.43428
NCOA1 nuclear receptor coactivator 1 1.43266
HSPB1 heat shock 27kDa protein 1 1.42642
GPAM glycerol-3-phosphate acyltransferase, mitochondrial 1.42508
CAV1 caveolin 1, caveolae protein, 22kDa 1.42454
SCARB1 scavenger receptor class B, member 1 1.42211
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.41856
IGF1R insulin-like growth factor 1 receptor 1.41748
MSMO1 methylsterol monooxygenase 1 1.41586
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 1.41257
CCNE1 cyclin E1 1.41202
APOB apolipoprotein B 1.41146
TALDO1 transaldolase 1 1.4026
CCNA2 cyclin A2 1.3973
RB1 retinoblastoma 1 1.39507
CASP4 caspase 4, apoptosis-related cysteine peptidase 1.39282
XDH xanthine dehydrogenase 1.3903
VIM vimentin 1.3903
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.38327
TIMP1 TIMP metallopeptidase inhibitor 1 1.38156
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.37389
MAOA monoamine oxidase A 1.37389
MAP2K6 mitogen-activated protein kinase kinase 6 1.37389
PDK1 pyruvate dehydrogenase kinase, isozyme 1 1.37389
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 1.37275
FN1 fibronectin 1 1.37275
PCNA proliferating cell nuclear antigen 1.37246
DPP4 dipeptidyl-peptidase 4 1.37018
JAK1 Janus kinase 1 1.37018
AR androgen receptor 1.36905
SELE selectin E 1.36876
G6PC glucose-6-phosphatase, catalytic subunit 1.36791
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1 1.36648
NCF1 neutrophil cytosolic factor 1 1.36619
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.3639
SGK1 serum/glucocorticoid regulated kinase 1 1.36361
NUPR1 nuclear protein, transcriptional regulator, 1 1.36361
EGFR epidermal growth factor receptor 1.36019
ITGAV integrin, alpha V 1.35991
GADD45A growth arrest and DNA-damage-inducible, alpha 1.35849
CCND2 cyclin D2 1.35618
HSPA9 heat shock 70kDa protein 9 (mortalin) 1.35299
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.34897
LDHA lactate dehydrogenase A 1.3443
ATF4 activating transcription factor 4 1.34372
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 1.34111
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6 1.3388
KLF4 Kruppel-like factor 4 (gut) 1.33464
RXRB retinoid X receptor, beta 1.33375
THBS1 thrombospondin 1 1.32993
MPO myeloperoxidase 1.32607
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.32577
CTSD cathepsin D 1.32192
NR1H3 nuclear receptor subfamily 1, group H, member 3 1.32103
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 1.32103
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 1.31807
ACSL5 acyl-CoA synthetase long-chain family member 5 1.31686
FABP1 fatty acid binding protein 1, liver 1.31596
CLU clusterin 1.30574
DNMT1 DNA (cytosine-5-)-methyltransferase 1 1.30482
IDI1 isopentenyl-diphosphate delta isomerase 1 1.30117
MTTP microsomal triglyceride transfer protein 1.29626
PDIA3 protein disulfide isomerase family A, member 3 1.29133
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.29133
MAPK14 mitogen-activated protein kinase 14 1.2898
INSIG1 insulin induced gene 1 1.28858
ARNTL aryl hydrocarbon receptor nuclear translocator-like 1.2861
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 1.28425
NR1H4 nuclear receptor subfamily 1, group H, member 4 1.2818
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 1.28058
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2 1.27782
IL1A interleukin 1, alpha 1.27471
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.27347
IGFBP5 insulin-like growth factor binding protein 5 1.27255
SNCA synuclein, alpha (non A4 component of amyloid precursor) 1.27039
IL2 interleukin 2 1.26947
SREBF2 sterol regulatory element binding transcription factor 2 1.267
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 1.26607
TFF1 trefoil factor 1 1.26298
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 1.26236
GSTP1 glutathione S-transferase pi 1 1.26144
AGTR2 angiotensin II receptor, type 2 1.25776
CASP2 caspase 2, apoptosis-related cysteine peptidase 1.25776
CCL5 chemokine (C-C motif) ligand 5 1.25619
LHB luteinizing hormone beta polypeptide 1.25338
CXCL8 chemokine (C-X-C motif) ligand 8 1.25276
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 1.24905
MKI67 marker of proliferation Ki-67 1.24812
RUNX2 runt-related transcription factor 2 1.24623
CASP6 caspase 6, apoptosis-related cysteine peptidase 1.24307
CD14 CD14 molecule 1.24087
BID BH3 interacting domain death agonist 1.24087
TIMP3 TIMP metallopeptidase inhibitor 3 1.24024
MAOB monoamine oxidase B 1.24024
RORA RAR-related orphan receptor A 1.23993
JUNB jun B proto-oncogene 1.23775
DDIT4 DNA-damage-inducible transcript 4 1.23616
CLDN4 claudin 4 1.23552
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 1.23456
TSHB thyroid stimulating hormone, beta 1.23424
TIMP2 TIMP metallopeptidase inhibitor 2 1.2336
CCL3 chemokine (C-C motif) ligand 3 1.2336
MMP3 matrix metallopeptidase 3 1.23137
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 1.23137
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 1.22916
GSTA2 glutathione S-transferase alpha 2 1.22821
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.22727
CHUK conserved helix-loop-helix ubiquitous kinase 1.22339
JAK2 Janus kinase 2 1.22339
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 1.22177
STAT1 signal transducer and activator of transcription 1, 91kDa 1.22112
DUSP6 dual specificity phosphatase 6 1.22048
CXCL12 chemokine (C-X-C motif) ligand 12 1.21951
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 1.21759
KEAP1 kelch-like ECH-associated protein 1 1.21501
BIRC2 baculoviral IAP repeat containing 2 1.21501
DYNLL1 dynein, light chain, LC8-type 1 1.2137
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 1.2137
LGALS1 lectin, galactoside-binding, soluble, 1 1.2137
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 1.21239
ESR2 estrogen receptor 2 (ER beta) 1.21076
FDPS farnesyl diphosphate synthase 1.21043
EIF2A eukaryotic translation initiation factor 2A, 65kDa 1.21011
CPT2 carnitine palmitoyltransferase 2 1.21011
CFLAR CASP8 and FADD-like apoptosis regulator 1.20978
CRH corticotropin releasing hormone 1.20978
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 1.20719
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 1.20719
LIPC lipase, hepatic 1.20622
EEF2 eukaryotic translation elongation factor 2 1.20394
APOC1 apolipoprotein C-I 1.20295
TFAM transcription factor A, mitochondrial 1.20196
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 1.19933
UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9 1.199
FADS1 fatty acid desaturase 1 1.19802
PRLR prolactin receptor 1.19412
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.19345
DCLK1 doublecortin-like kinase 1 1.19246
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit 1.19246
IRAK1 interleukin-1 receptor-associated kinase 1 1.19246
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 1.19113
HSPA1B heat shock 70kDa protein 1B 1.18816
CASP12 caspase 12 (gene/pseudogene) 1.18783
IGFBP4 insulin-like growth factor binding protein 4 1.1862
ATF6 activating transcription factor 6 1.1862
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 1.1862
ALDOC aldolase C, fructose-bisphosphate 1.1862
CPT1B carnitine palmitoyltransferase 1B (muscle) 1.1862
KDR kinase insert domain receptor 1.18554
BMP2 bone morphogenetic protein 2 1.18159
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 1.18093
ALPL alkaline phosphatase, liver/bone/kidney 1.18059
SOCS3 suppressor of cytokine signaling 3 1.18059
CRY1 cryptochrome circadian clock 1 1.17563
SQLE squalene epoxidase 1.17563
IRS2 insulin receptor substrate 2 1.17464
NR1D1 nuclear receptor subfamily 1, group D, member 1 1.17464
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.17464
LDHB lactate dehydrogenase B 1.17464
CRYAB crystallin, alpha B 1.173
EGR2 early growth response 2 1.17268
CLDN1 claudin 1 1.17101
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 1.17034
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7 1.16799
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 1.16733
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 1.16633
CXCL10 chemokine (C-X-C motif) ligand 10 1.16533
CREBBP CREB binding protein 1.16368
S100B S100 calcium binding protein B 1.16335
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 1.16302
PAH phenylalanine hydroxylase 1.16302
SIAH2 siah E3 ubiquitin protein ligase 2 1.16236
UGP2 UDP-glucose pyrophosphorylase 2 1.16236
UFM1 ubiquitin-fold modifier 1 1.16137
TRIB3 tribbles pseudokinase 3 1.1607
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit 1.15967
NCL nucleolin 1.15831
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 1.15763
PTGES prostaglandin E synthase 1.15256
FABP3 fatty acid binding protein 3, muscle and heart 1.15256
PLD1 phospholipase D1, phosphatidylcholine-specific 1.15256
CTGF connective tissue growth factor 1.14919
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.14919
ATM ATM serine/threonine kinase 1.14816
EGF epidermal growth factor 1.14713
TPI1 triosephosphate isomerase 1 1.14541
MGLL monoglyceride lipase 1.14541
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 1.1437
CXCL2 chemokine (C-X-C motif) ligand 2 1.14302
IL18 interleukin 18 1.13895
CXCL5 chemokine (C-X-C motif) ligand 5 1.13827
CA2 carbonic anhydrase II 1.13724
PRKCB protein kinase C, beta 1.13724
PKM pyruvate kinase, muscle 1.13724
ACE angiotensin I converting enzyme 1.13621
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 1.13552
GCK glucokinase (hexokinase 4) 1.13484
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 1.13449
GSK3A glycogen synthase kinase 3 alpha 1.13177
EPO erythropoietin 1.13177
TXNRD1 thioredoxin reductase 1 1.13143
ENC1 ectodermal-neural cortex 1 (with BTB domain) 1.13143
EGR3 early growth response 3 1.13109
VNN1 vanin 1 1.13109
VCAN versican 1.13109
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 1.1294
BIRC5 baculoviral IAP repeat containing 5 1.12906
GJA1 gap junction protein, alpha 1, 43kDa 1.12906
S100A6 S100 calcium binding protein A6 1.12805
PTGES2 prostaglandin E synthase 2 1.12599
ADIPOR1 adiponectin receptor 1 1.12599
PDX1 pancreatic and duodenal homeobox 1 1.12564
HNF4A hepatocyte nuclear factor 4, alpha 1.12461
CKB creatine kinase, brain 1.12461
FGF2 fibroblast growth factor 2 (basic) 1.12288
GSN gelsolin 1.12117
ACHE acetylcholinesterase (Yt blood group) 1.12048
BCL10 B-cell CLL/lymphoma 10 1.12014
LIPG lipase, endothelial 1.12014
AGR2 anterior gradient 2 1.12014
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 1.11809
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 1.11809
ORM1 orosomucoid 1 1.11775
MCL1 myeloid cell leukemia 1 1.11536
TLR2 toll-like receptor 2 1.11536
NPPB natriuretic peptide B 1.11536
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11 1.11396
LCAT lecithin-cholesterol acyltransferase 1.11396
GFAP glial fibrillary acidic protein 1.11116
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 1.10977
RBP4 retinol binding protein 4, plasma 1.10977
BSG basigin (Ok blood group) 1.10872
RETN resistin 1.10562
ANGPTL4 angiopoietin-like 4 1.10459
WSB1 WD repeat and SOCS box containing 1 1.10317
TXNIP thioredoxin interacting protein 1.10175
CCND3 cyclin D3 1.09927
DIO2 deiodinase, iodothyronine, type II 1.09822
GFRA1 GDNF family receptor alpha 1 1.09786
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 1.09716
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 1.09716
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 1.09506
IRX3 iroquois homeobox 3 1.09401
DGAT2 diacylglycerol O-acyltransferase 2 1.09332
SLC27A1 solute carrier family 27 (fatty acid transporter), member 1 1.09262
CAMK4 calcium/calmodulin-dependent protein kinase IV 1.09262
IVNS1ABP influenza virus NS1A binding protein 1.09226
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 1.09226
PPP1R15A protein phosphatase 1, regulatory subunit 15A 1.09154
IGFBP3 insulin-like growth factor binding protein 3 1.09119
MT2A metallothionein 2A 1.09119
STIP1 stress-induced phosphoprotein 1 1.0894
FBP1 fructose-1,6-bisphosphatase 1 1.0894
CHEK2 checkpoint kinase 2 1.08868
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.08868
PGR progesterone receptor 1.08762
SMC2 structural maintenance of chromosomes 2 1.0869
UROD uroporphyrinogen decarboxylase 1.08655
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10 1.08655
FAM162A family with sequence similarity 162, member A 1.08655
ZDHHC2 zinc finger, DHHC-type containing 2 1.08655
TGFB2 transforming growth factor, beta 2 1.08619
CDK1 cyclin-dependent kinase 1 1.08584
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 1.08549
GCH1 GTP cyclohydrolase 1 1.08549
COMT catechol-O-methyltransferase 1.08442
BAK1 BCL2-antagonist/killer 1 1.08372
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.08301
TAGLN transgelin 1.08231
CCL22 chemokine (C-C motif) ligand 22 1.08196
NGFR nerve growth factor receptor 1.08126
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 1.08126
ACE2 angiotensin I converting enzyme 2 1.07947
ARPP19 cAMP-regulated phosphoprotein, 19kDa 1.07947
ICAM3 intercellular adhesion molecule 3 1.07947
PGD phosphogluconate dehydrogenase 1.07911
SH3BGRL2 SH3 domain binding glutamate-rich protein like 2 1.07911
FOSB FBJ murine osteosarcoma viral oncogene homolog B 1.07911
PAQR9 progestin and adipoQ receptor family member IX 1.07911
FYN FYN proto-oncogene, Src family tyrosine kinase 1.07732
CCK cholecystokinin 1.07376
C1S complement component 1, s subcomponent 1.07376
CD9 CD9 molecule 1.07376
NDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa 1.07199
DLD dihydrolipoamide dehydrogenase 1.07163
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.07163
SHBG sex hormone-binding globulin 1.07022
CD68 CD68 molecule 1.06987
CBS cystathionine-beta-synthase 1.06987
CYP8B1 cytochrome P450, family 8, subfamily B, polypeptide 1 1.06987
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 1.06808
C10ORF10 chromosome 10 open reading frame 10 1.06661
NR5A1 nuclear receptor subfamily 5, group A, member 1 1.06661
PDK4 pyruvate dehydrogenase kinase, isozyme 4 1.06406
CLK1 CDC-like kinase 1 1.06152
NGF nerve growth factor (beta polypeptide) 1.06116
E2F1 E2F transcription factor 1 1.06116
GADD45G growth arrest and DNA-damage-inducible, gamma 1.06116
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 1.05828
NUCB2 nucleobindin 2 1.05685
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 1.0561
CDKN2A cyclin-dependent kinase inhibitor 2A 1.05498
MGMT O-6-methylguanine-DNA methyltransferase 1.05386
GSTM3 glutathione S-transferase mu 3 (brain) 1.05386
CHEK1 checkpoint kinase 1 1.05386
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 1.052
MALAT1 metastasis associated lung adenocarcinoma transcript 1 (non-protein coding) 1.052
PLTP phospholipid transfer protein 1.052
AGTR1 angiotensin II receptor, type 1 1.05089
RPS6 ribosomal protein S6 1.04904
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 1.04904
ECH1 enoyl CoA hydratase 1, peroxisomal 1.04721
CKS1B CDC28 protein kinase regulatory subunit 1B 1.04684
PDGFRB platelet-derived growth factor receptor, beta polypeptide 1.04611
APOC2 apolipoprotein C-II 1.04465
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 1.04352
APOA1 apolipoprotein A-I 1.04276
TOP2A topoisomerase (DNA) II alpha 170kDa 1.04276
PLAT plasminogen activator, tissue 1.04276
INHBB inhibin, beta B 1.04239
DUSP10 dual specificity phosphatase 10 1.04239
PTPN11 protein tyrosine phosphatase, non-receptor type 11 1.04201
CALR calreticulin 1.04051
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 1.04051
CD44 CD44 molecule (Indian blood group) 1.03939
NAPEPLD N-acyl phosphatidylethanolamine phospholipase D 1.03715
OSBPL8 oxysterol binding protein-like 8 1.03715
TIMM10 translocase of inner mitochondrial membrane 10 homolog (yeast) 1.03678
CD40 CD40 molecule, TNF receptor superfamily member 5 1.03456
MAP2K3 mitogen-activated protein kinase kinase 3 1.03271
MYH7 myosin, heavy chain 7, cardiac muscle, beta 1.03271
CDC25C cell division cycle 25C 1.03197
PRKCE protein kinase C, epsilon 1.03197
FGL1 fibrinogen-like 1 1.03159
IL12B interleukin 12B 1.02933
ARRDC3 arrestin domain containing 3 1.02821
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 1.02821
SQSTM1 sequestosome 1 1.02746
ACAD11 acyl-CoA dehydrogenase family, member 11 1.02708
PHB prohibitin 1.02596
PNPLA3 patatin-like phospholipase domain containing 3 1.02522
HACL1 2-hydroxyacyl-CoA lyase 1 1.02485
COL6A3 collagen, type VI, alpha 3 1.02373
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial) 1.02373
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.02299
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 1.02225
HRAS Harvey rat sarcoma viral oncogene homolog 1.02077
BBC3 BCL2 binding component 3 1.02077
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.02077
ADAM9 ADAM metallopeptidase domain 9 1.0189
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 1.0189
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 1.01814
CCDC88A coiled-coil domain containing 88A 1.01776
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2 1.01776
TGIF2 TGFB-induced factor homeobox 2 1.01776
SHB Src homology 2 domain containing adaptor protein B 1.01776
ARNT aryl hydrocarbon receptor nuclear translocator 1.01776
CYBB cytochrome b-245, beta polypeptide 1.01512
FABP7 fatty acid binding protein 7, brain 1.01474
BIK BCL2-interacting killer (apoptosis-inducing) 1.01474
SLCO2B1 solute carrier organic anion transporter family, member 2B1 1.01474
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) 1.01474
CD86 CD86 molecule 1.01361
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa 1.01286
SKAP2 src kinase associated phosphoprotein 2 1.01286
CBX5 chromobox homolog 5 1.01286
CCPG1 cell cycle progression 1 1.01286
ANXA5 annexin A5 1.01249
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase 1.01212
PPP1R3C protein phosphatase 1, regulatory subunit 3C 1.01025
ANPEP alanyl (membrane) aminopeptidase 1.01025
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 1.01025