Neurotoxicity Syndromes Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
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Genes

43 genes associated with the Neurotoxicity Syndromes phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
AGXT alanine-glyoxylate aminotransferase
AHR aryl hydrocarbon receptor
BRCA1 breast cancer 1, early onset
COMT catechol-O-methyltransferase
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DPYD dihydropyrimidine dehydrogenase
DRD2 dopamine receptor D2
DRD4 dopamine receptor D4
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ERCC1 excision repair cross-complementation group 1
ERCC2 excision repair cross-complementation group 2
FANCD2 Fanconi anemia, complementation group D2
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
ICAM1 intercellular adhesion molecule 1
MBP myelin basic protein
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NME1 NME/NM23 nucleoside diphosphate kinase 1
PPARD peroxisome proliferator-activated receptor delta
SCN10A sodium channel, voltage gated, type X alpha subunit
SCN4A sodium channel, voltage gated, type IV alpha subunit
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SLCO1B3 solute carrier organic anion transporter family, member 1B3
TNF tumor necrosis factor
TYMS thymidylate synthetase
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3