Neuronal System Gene Set

Dataset Reactome Pathways
Category structural or functional annotations
Type pathway
External Link http://www.reactome.org/PathwayBrowser/#/R-HSA-112316
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Genes

280 proteins participating in the Neuronal System pathway from the Reactome Pathways dataset.

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
ACHE acetylcholinesterase (Yt blood group)
ACTN2 actinin, alpha 2
ADCY1 adenylate cyclase 1 (brain)
ADCY2 adenylate cyclase 2 (brain)
ADCY3 adenylate cyclase 3
ADCY4 adenylate cyclase 4
ADCY5 adenylate cyclase 5
ADCY6 adenylate cyclase 6
ADCY7 adenylate cyclase 7
ADCY8 adenylate cyclase 8 (brain)
ADCY9 adenylate cyclase 9
AKAP5 A kinase (PRKA) anchor protein 5
AKAP9 A kinase (PRKA) anchor protein 9
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
AP2A1 adaptor-related protein complex 2, alpha 1 subunit
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
AP2B1 adaptor-related protein complex 2, beta 1 subunit
AP2M1 adaptor-related protein complex 2, mu 1 subunit
AP2S1 adaptor-related protein complex 2, sigma 1 subunit
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9
BCHE butyrylcholinesterase
BRAF B-Raf proto-oncogene, serine/threonine kinase
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CACNG2 calcium channel, voltage-dependent, gamma subunit 2
CACNG3 calcium channel, voltage-dependent, gamma subunit 3
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CACNG8 calcium channel, voltage-dependent, gamma subunit 8
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CAMK2D calcium/calmodulin-dependent protein kinase II delta
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CAMK4 calcium/calmodulin-dependent protein kinase IV
CAMKK1 calcium/calmodulin-dependent protein kinase kinase 1, alpha
CHAT choline O-acetyltransferase
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle)
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal)
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal)
CHRND cholinergic receptor, nicotinic, delta (muscle)
CHRNE cholinergic receptor, nicotinic, epsilon (muscle)
CHRNG cholinergic receptor, nicotinic, gamma (muscle)
COMT catechol-O-methyltransferase
CPLX1 complexin 1
CREB1 cAMP responsive element binding protein 1
DLG1 discs, large homolog 1 (Drosophila)
DLG3 discs, large homolog 3 (Drosophila)
DLG4 discs, large homolog 4 (Drosophila)
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5
EPB41L1 erythrocyte membrane protein band 4.1-like 1
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GABRA3 gamma-aminobutyric acid (GABA) A receptor, alpha 3
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5
GABRA6 gamma-aminobutyric acid (GABA) A receptor, alpha 6
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3
GABRQ gamma-aminobutyric acid (GABA) A receptor, theta
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GABRR3 gamma-aminobutyric acid (GABA) A receptor, rho 3 (gene/pseudogene)
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GJA10 gap junction protein, alpha 10, 62kDa
GJC1 gap junction protein, gamma 1, 45kDa
GJD2 gap junction protein, delta 2, 36kDa
GLS glutaminase
GLS2 glutaminase 2 (liver, mitochondrial)
GLUL glutamate-ammonia ligase
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
GNAT3 guanine nucleotide binding protein, alpha transducing 3
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GNB4 guanine nucleotide binding protein (G protein), beta polypeptide 4
GNB5 guanine nucleotide binding protein (G protein), beta 5
GNG10 guanine nucleotide binding protein (G protein), gamma 10
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GNG12 guanine nucleotide binding protein (G protein), gamma 12
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GNG2 guanine nucleotide binding protein (G protein), gamma 2
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GNG5 guanine nucleotide binding protein (G protein), gamma 5
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GNG8 guanine nucleotide binding protein (G protein), gamma 8
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
GNGT2 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIA2 glutamate receptor, ionotropic, AMPA 2
GRIA3 glutamate receptor, ionotropic, AMPA 3
GRIA4 glutamate receptor, ionotropic, AMPA 4
GRIK1 glutamate receptor, ionotropic, kainate 1
GRIK2 glutamate receptor, ionotropic, kainate 2
GRIK3 glutamate receptor, ionotropic, kainate 3
GRIK4 glutamate receptor, ionotropic, kainate 4
GRIK5 glutamate receptor, ionotropic, kainate 5
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D
GRIP1 glutamate receptor interacting protein 1
GRIP2 glutamate receptor interacting protein 2
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HCN3 hyperpolarization activated cyclic nucleotide gated potassium channel 3
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HRAS Harvey rat sarcoma viral oncogene homolog
HSPA8 heat shock 70kDa protein 8
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1
KCNA10 potassium channel, voltage gated shaker related subfamily A, member 10
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KCNA4 potassium channel, voltage gated shaker related subfamily A, member 4
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6
KCNA7 potassium channel, voltage gated shaker related subfamily A, member 7
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KCNAB3 potassium channel, voltage gated subfamily A regulatory beta subunit 3
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1
KCNB2 potassium channel, voltage gated Shab related subfamily B, member 2
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1
KCNC2 potassium channel, voltage gated Shaw related subfamily C, member 2
KCNC3 potassium channel, voltage gated Shaw related subfamily C, member 3
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4
KCND1 potassium channel, voltage gated Shal related subfamily D, member 1
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KCNG2 potassium channel, voltage gated modifier subfamily G, member 2
KCNG3 potassium channel, voltage gated modifier subfamily G, member 3
KCNG4 potassium channel, voltage gated modifier subfamily G, member 4
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNH3 potassium channel, voltage gated eag related subfamily H, member 3
KCNH4 potassium channel, voltage gated eag related subfamily H, member 4
KCNH5 potassium channel, voltage gated eag related subfamily H, member 5
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6
KCNH7 potassium channel, voltage gated eag related subfamily H, member 7
KCNH8 potassium channel, voltage gated eag related subfamily H, member 8
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9
KCNK1 potassium channel, two pore domain subfamily K, member 1
KCNK10 potassium channel, two pore domain subfamily K, member 10
KCNK13 potassium channel, two pore domain subfamily K, member 13
KCNK16 potassium channel, two pore domain subfamily K, member 16
KCNK17 potassium channel, two pore domain subfamily K, member 17
KCNK18 potassium channel, two pore domain subfamily K, member 18
KCNK2 potassium channel, two pore domain subfamily K, member 2
KCNK3 potassium channel, two pore domain subfamily K, member 3
KCNK4 potassium channel, two pore domain subfamily K, member 4
KCNK6 potassium channel, two pore domain subfamily K, member 6
KCNK7 potassium channel, two pore domain subfamily K, member 7
KCNK9 potassium channel, two pore domain subfamily K, member 9
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KCNMB2 potassium channel subfamily M regulatory beta subunit 2
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
KCNQ4 potassium channel, voltage gated KQT-like subfamily Q, member 4
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KCNS2 potassium voltage-gated channel, modifier subfamily S, member 2
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KCNV1 potassium channel, voltage gated modifier subfamily V, member 1
KCNV2 potassium channel, voltage gated modifier subfamily V, member 2
MAOA monoamine oxidase A
MAPK1 mitogen-activated protein kinase 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MYO6 myosin VI
NCALD neurocalcin delta
NEFL neurofilament, light polypeptide
NSF N-ethylmaleimide-sensitive factor
PANX1 pannexin 1
PANX2 pannexin 2
PDPK1 3-phosphoinositide dependent protein kinase 1
PICK1 protein interacting with PRKCA 1
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLCB2 phospholipase C, beta 2
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
PPFIA2 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRKCG protein kinase C, gamma
RAB3A RAB3A, member RAS oncogene family
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RASGRF2 Ras protein-specific guanine nucleotide-releasing factor 2
RIMS1 regulating synaptic membrane exocytosis 1
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
RRAS related RAS viral (r-ras) oncogene homolog
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC1A6 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SLC22A2 solute carrier family 22 (organic cation transporter), member 2
SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1
SLC38A1 solute carrier family 38, member 1
SLC38A2 solute carrier family 38, member 2
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SNAP25 synaptosomal-associated protein, 25kDa
STX1A syntaxin 1A (brain)
STXBP1 syntaxin binding protein 1
SYN1 synapsin I
SYN2 synapsin II
SYN3 synapsin III
SYT1 synaptotagmin I
UNC13B unc-13 homolog B (C. elegans)
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)