Neuroleptic Malignant Syndrome Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D009459
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Genes

69 genes/proteins associated with the disease Neuroleptic Malignant Syndrome from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
DRD2 dopamine receptor D2 2.3853
PRL prolactin 2.27464
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 2.20345
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 2.17727
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 2.09191
DRD1 dopamine receptor D1 2.05244
BDNF brain-derived neurotrophic factor 2.01979
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.93798
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 1.78492
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 1.77994
FOS FBJ murine osteosarcoma viral oncogene homolog 1.75102
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 1.65445
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.59966
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 1.54669
MAPK8 mitogen-activated protein kinase 8 1.48556
EGR1 early growth response 1 1.45883
CRH corticotropin releasing hormone 1.45537
SOD1 superoxide dismutase 1, soluble 1.44735
DRD3 dopamine receptor D3 1.42074
MAPK1 mitogen-activated protein kinase 1 1.39535
MAOB monoamine oxidase B 1.35821
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.33346
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.33081
MAPK3 mitogen-activated protein kinase 3 1.32577
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.30635
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.2975
BCL2 B-cell CLL/lymphoma 2 1.2944
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.28303
BAX BCL2-associated X protein 1.26732
FOSB FBJ murine osteosarcoma viral oncogene homolog B 1.26576
INS insulin 1.23962
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 1.2336
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 1.22758
GSK3B glycogen synthase kinase 3 beta 1.2208
ARC activity-regulated cytoskeleton-associated protein 1.21304
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 1.20978
BCHE butyrylcholinesterase 1.20361
CAT catalase 1.18882
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 1.18783
CALM2 calmodulin 2 (phosphorylase kinase, delta) 1.18521
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.18326
CDK5 cyclin-dependent kinase 5 1.18093
TH tyrosine hydroxylase 1.17959
TAC1 tachykinin, precursor 1 1.17827
TNF tumor necrosis factor 1.173
CAMK4 calcium/calmodulin-dependent protein kinase IV 1.16035
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 1.1529
MAPK14 mitogen-activated protein kinase 14 1.13895
GRIA2 glutamate receptor, ionotropic, AMPA 2 1.13793
AP2B1 adaptor-related protein complex 2, beta 1 subunit 1.13552
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.12391
CREB1 cAMP responsive element binding protein 1 1.12185
HOMER1 homer scaffolding protein 1 1.11673
RELN reelin 1.11673
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.09786
JUNB jun B proto-oncogene 1.09541
PENK proenkephalin 1.0919
ACHE acetylcholinesterase (Yt blood group) 1.08797
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 1.08797
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 1.07911
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.07199
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.07093
DUSP1 dual specificity phosphatase 1 1.06297
FOSL2 FOS-like antigen 2 1.05052
CES1 carboxylesterase 1 1.04201
NCAN neurocan 1.03604
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta 1.03308
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 1.03308
GSK3A glycogen synthase kinase 3 alpha 1.0204