Neoplasms, Squamous Cell Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
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Genes

50 genes associated with the Neoplasms, Squamous Cell phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AHR aryl hydrocarbon receptor
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
BRAF B-Raf proto-oncogene, serine/threonine kinase
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP6 caspase 6, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CDKN2A cyclin-dependent kinase inhibitor 2A
CLPTM1L CLPTM1-like
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
EGFR epidermal growth factor receptor
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ERCC1 excision repair cross-complementation group 1
GPX1 glutathione peroxidase 1
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HLA-G major histocompatibility complex, class I, G
HMOX1 heme oxygenase 1
IL6 interleukin 6
KRAS Kirsten rat sarcoma viral oncogene homolog
MDM4 MDM4, p53 regulator
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MPO myeloperoxidase
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NQO1 NAD(P)H dehydrogenase, quinone 1
OGG1 8-oxoguanine DNA glycosylase
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
POT1 protection of telomeres 1
SHMT1 serine hydroxymethyltransferase 1 (soluble)
TERF1 telomeric repeat binding factor (NIMA-interacting) 1
TERF2 telomeric repeat binding factor 2
TERT telomerase reverse transcriptase
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TP53 tumor protein p53
TYMS thymidylate synthetase
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3