Neoplasms, Multiple Primary Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
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Genes

58 genes associated with the Neoplasms, Multiple Primary phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
APC adenomatous polyposis coli
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
CCND1 cyclin D1
CDK4 cyclin-dependent kinase 4
CDKN2A cyclin-dependent kinase inhibitor 2A
CHEK2 checkpoint kinase 2
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DNAH1 dynein, axonemal, heavy chain 1
EGFR epidermal growth factor receptor
ERCC2 excision repair cross-complementation group 2
FGFR3 fibroblast growth factor receptor 3
GSTM1 glutathione S-transferase mu 1
GSTM3 glutathione S-transferase mu 3 (brain)
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HFE hemochromatosis
IL4 interleukin 4
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KRAS Kirsten rat sarcoma viral oncogene homolog
LRFN2 leucine rich repeat and fibronectin type III domain containing 2
MAX MYC associated factor X
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MITF microphthalmia-associated transcription factor
MLH1 mutL homolog 1
MSH2 mutS homolog 2
MSH6 mutS homolog 6
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MUTYH mutY homolog
MYH1 myosin, heavy chain 1, skeletal muscle, adult
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NBN nibrin
NF1 neurofibromin 1
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1
OGG1 8-oxoguanine DNA glycosylase
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
RB1 retinoblastoma 1
RET ret proto-oncogene
SDHAF2 succinate dehydrogenase complex assembly factor 2
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SHFM1 split hand/foot malformation (ectrodactyly) type 1
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
TMEM127 transmembrane protein 127
TNF tumor necrosis factor
TP53 tumor protein p53
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3