Neoplasms, Hormone-Dependent Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
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Genes

45 genes associated with the Neoplasms, Hormone-Dependent phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
AKR1C3 aldo-keto reductase family 1, member C3
AR androgen receptor
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
COL18A1 collagen, type XVIII, alpha 1
COMT catechol-O-methyltransferase
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
EGF epidermal growth factor
ERCC1 excision repair cross-complementation group 1
ERCC2 excision repair cross-complementation group 2
ESR2 estrogen receptor 2 (ER beta)
FGFR2 fibroblast growth factor receptor 2
GLDN gliomedin
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
KLK3 kallikrein-related peptidase 3
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
PARP1 poly (ADP-ribose) polymerase 1
PGR progesterone receptor
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PTEN phosphatase and tensin homolog
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SHBG sex hormone-binding globulin
SIAH2 siah E3 ubiquitin protein ligase 2
SLCO1B3 solute carrier organic anion transporter family, member 1B3
SLCO2B1 solute carrier organic anion transporter family, member 2B1
SOD2 superoxide dismutase 2, mitochondrial
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
TGFB1 transforming growth factor, beta 1
TP53 tumor protein p53
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1