Necrosis Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
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Genes

24 genes associated with the Necrosis phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AKT1 v-akt murine thymoma viral oncogene homolog 1
APOL1 apolipoprotein L, 1
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
EGFR epidermal growth factor receptor
F2 coagulation factor II (thrombin)
F5 coagulation factor V (proaccelerin, labile factor)
FAS Fas cell surface death receptor
HLA-B major histocompatibility complex, class I, B
HRAS Harvey rat sarcoma viral oncogene homolog
KRAS Kirsten rat sarcoma viral oncogene homolog
MMP1 matrix metallopeptidase 1
MMP3 matrix metallopeptidase 3
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
RET ret proto-oncogene
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
TGFB1 transforming growth factor, beta 1
TLR4 toll-like receptor 4
TNF tumor necrosis factor