Nausea Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A sensation of unease in the stomach together with an urge to vomit. (Human Phenotype Ontology, HP_0002018)
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Genes

43 genes associated with the Nausea phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ARRB2 arrestin, beta 2
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
CHRM3 cholinergic receptor, muscarinic 3
CHRM5 cholinergic receptor, muscarinic 5
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CNR1 cannabinoid receptor 1 (brain)
COMT catechol-O-methyltransferase
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
ERCC1 excision repair cross-complementation group 1
ERCC2 excision repair cross-complementation group 2
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HRH1 histamine receptor H1
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
HTR3C 5-hydroxytryptamine (serotonin) receptor 3C, ionotropic
HTR3D 5-hydroxytryptamine (serotonin) receptor 3D, ionotropic
HTR3E 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic
KRAS Kirsten rat sarcoma viral oncogene homolog
MAOA monoamine oxidase A
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
OPRK1 opioid receptor, kappa 1
OPRM1 opioid receptor, mu 1
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TACR1 tachykinin receptor 1
TPH1 tryptophan hydroxylase 1
TPMT thiopurine S-methyltransferase
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7