NLRP12 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description NLR family, pyrin domain containing 12|This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Mutations in this gene cause familial cold autoinflammatory syndrome type 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013] (NCBI Entrez Gene Database, 91662)
External Link http://www.ncbi.nlm.nih.gov/gene/91662
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Genes

22 interacting proteins for NLRP12 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
AARSD1 alanyl-tRNA synthetase domain containing 1
CACYBP calcyclin binding protein
CDC37 cell division cycle 37
FAF1 Fas (TNFRSF6) associated factor 1
FKBP5 FK506 binding protein 5
FKBPL FK506 binding protein like
HSF2 heat shock transcription factor 2
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA4 heat shock 70kDa protein 4
HSPA8 heat shock 70kDa protein 8
IRAK1 interleukin-1 receptor-associated kinase 1
MLF1 myeloid leukemia factor 1
MLF2 myeloid leukemia factor 2
NUDCD3 NudC domain containing 3
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PXN paxillin
PYCARD PYD and CARD domain containing
PYDC2 pyrin domain containing 2
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
STIP1 stress-induced phosphoprotein 1
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TTC1 tetratricopeptide repeat domain 1