NCI-SNU-1 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
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Genes

355 genes with high or low expression in NCI-SNU-1 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
BMP10 bone morphogenetic protein 10 3.60177
SMNDC1 survival motor neuron domain containing 1 3.60177
FBLN2 fibulin 2 3.42287
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 3.37232
EBNA1BP2 EBNA1 binding protein 2 3.21353
NXF3 nuclear RNA export factor 3 3.19195
PIWIL1 piwi-like RNA-mediated gene silencing 1 3.06069
CCK cholecystokinin 2.94814
TLE2 transducin-like enhancer of split 2 2.89776
KLF2 Kruppel-like factor 2 2.89631
PKM pyruvate kinase, muscle 2.8706
ELOVL1 ELOVL fatty acid elongase 1 2.72006
THG1L tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) 2.69389
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative) 2.65634
RNF167 ring finger protein 167 2.64525
CDC20 cell division cycle 20 2.61118
PDLIM2 PDZ and LIM domain 2 (mystique) 2.61115
GLI2 GLI family zinc finger 2 2.60319
ENO3 enolase 3 (beta, muscle) 2.55714
PRUNE2 prune homolog 2 (Drosophila) 2.43081
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 2.42055
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 2.41443
CACNB4 calcium channel, voltage-dependent, beta 4 subunit 2.41116
ACADVL acyl-CoA dehydrogenase, very long chain 2.40226
MTMR11 myotubularin related protein 11 2.3865
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 2.36413
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 2.35109
NET1 neuroepithelial cell transforming 1 2.3333
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 2.31864
PRDX2 peroxiredoxin 2 2.30866
PYGB phosphorylase, glycogen; brain 2.29467
WSB1 WD repeat and SOCS box containing 1 2.28989
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 2.26716
PIAS3 protein inhibitor of activated STAT, 3 2.26368
ARL2BP ADP-ribosylation factor-like 2 binding protein 2.24774
ZCCHC8 zinc finger, CCHC domain containing 8 2.23246
TJP1 tight junction protein 1 2.22585
VCL vinculin 2.19791
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 2.19647
ENO2 enolase 2 (gamma, neuronal) 2.17101
TAS2R13 taste receptor, type 2, member 13 2.16943
PEX11B peroxisomal biogenesis factor 11 beta 2.16021
S100A5 S100 calcium binding protein A5 2.15747
GPI glucose-6-phosphate isomerase 2.13634
FKBP10 FK506 binding protein 10, 65 kDa 2.13369
GYS1 glycogen synthase 1 (muscle) 2.10585
SLC38A4 solute carrier family 38, member 4 2.10484
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 2.09822
PLLP plasmolipin 2.09636
ITGA10 integrin, alpha 10 2.09126
BMP2K BMP2 inducible kinase 2.0605
IFITM2 interferon induced transmembrane protein 2 2.04201
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 2.03811
NPAS2 neuronal PAS domain protein 2 2.03449
INPP1 inositol polyphosphate-1-phosphatase 2.0277
CASP10 caspase 10, apoptosis-related cysteine peptidase 2.0121
FABP6 fatty acid binding protein 6, ileal 2.01116
EMD emerin 2.0065
COX5B cytochrome c oxidase subunit Vb 1.98916
HSPB1 heat shock 27kDa protein 1 1.98272
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 1.98086
FXN frataxin 1.97615
ALDOA aldolase A, fructose-bisphosphate 1.97459
RAB27B RAB27B, member RAS oncogene family 1.9671
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4 1.96256
ZCWPW1 zinc finger, CW type with PWWP domain 1 1.95757
DENND2D DENN/MADD domain containing 2D 1.94357
PER1 period circadian clock 1 1.9426
PARP3 poly (ADP-ribose) polymerase family, member 3 1.93823
TEX14 testis expressed 14 1.91018
STAG3 stromal antigen 3 1.90499
TUBG2 tubulin, gamma 2 1.89278
PTPRH protein tyrosine phosphatase, receptor type, H 1.88859
MYO1C myosin IC 1.88789
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.88666
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4 1.88562
TTLL3 tubulin tyrosine ligase-like family member 3 1.88399
NR1H2 nuclear receptor subfamily 1, group H, member 2 1.88049
ATF4 activating transcription factor 4 1.87602
GPR182 G protein-coupled receptor 182 1.87339
BCOR BCL6 corepressor 1.87244
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 1.87105
EXOSC7 exosome component 7 1.86564
PLXNA1 plexin A1 1.84706
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 1.84193
CDC25B cell division cycle 25B 1.83996
CD34 CD34 molecule 1.83976
MAGEC1 melanoma antigen family C1 1.83973
ONECUT2 one cut homeobox 2 1.8388
S100A3 S100 calcium binding protein A3 1.83782
GADD45G growth arrest and DNA-damage-inducible, gamma 1.82692
PFKM phosphofructokinase, muscle 1.82184
SOSTDC1 sclerostin domain containing 1 1.8212
CCDC68 coiled-coil domain containing 68 1.81853
GADD45B growth arrest and DNA-damage-inducible, beta 1.81516
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 1.81455
COQ7 coenzyme Q7 homolog, ubiquinone (yeast) 1.80965
TGFBR3 transforming growth factor, beta receptor III 1.80913
AES amino-terminal enhancer of split 1.80614
THAP3 THAP domain containing, apoptosis associated protein 3 1.79181
FZD4 frizzled class receptor 4 1.78431
SFMBT1 Scm-like with four mbt domains 1 1.78309
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans) 1.76137
PRB4 proline-rich protein BstNI subfamily 4 1.75597
KAT5 K(lysine) acetyltransferase 5 1.75541
CSF1 colony stimulating factor 1 (macrophage) 1.75269
GPC1 glypican 1 1.73121
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.72284
CD93 CD93 molecule 1.72242
PPP1R15A protein phosphatase 1, regulatory subunit 15A 1.72166
MYO5C myosin VC 1.71836
CLK3 CDC-like kinase 3 1.70847
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 1.70232
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) 1.7012
SPRY2 sprouty homolog 2 (Drosophila) 1.69876
HHLA1 HERV-H LTR-associating 1 1.69437
PARP6 poly (ADP-ribose) polymerase family, member 6 1.68069
ACBD4 acyl-CoA binding domain containing 4 1.6762
S100A4 S100 calcium binding protein A4 1.67003
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 1.66966
TXNL1 thioredoxin-like 1 1.6686
THOC6 THO complex 6 1.66802
CTTNBP2NL CTTNBP2 N-terminal like 1.66705
CRYBB2 crystallin, beta B2 1.66084
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 1.65918
FAM63B family with sequence similarity 63, member B 1.65912
MEF2D myocyte enhancer factor 2D 1.6555
IL27RA interleukin 27 receptor, alpha 1.64754
GYG1 glycogenin 1 1.6389
NDRG3 NDRG family member 3 1.63086
BBC3 BCL2 binding component 3 1.62895
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1) 1.62149
SMAD6 SMAD family member 6 1.62058
LMCD1 LIM and cysteine-rich domains 1 1.61769
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled 1.61738
CNTNAP3B contactin associated protein-like 3B 1.61692
GAMT guanidinoacetate N-methyltransferase 1.61443
SPHK1 sphingosine kinase 1 1.59186
ING3 inhibitor of growth family, member 3 1.58033
ZNF467 zinc finger protein 467 1.57314
GATA6 GATA binding protein 6 1.56667
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 1.5662
AIP aryl hydrocarbon receptor interacting protein 1.5654
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent) 1.55849
UNC13A unc-13 homolog A (C. elegans) 1.55704
LAMB2 laminin, beta 2 (laminin S) 1.55696
PTH1R parathyroid hormone 1 receptor 1.55678
RIN1 Ras and Rab interactor 1 1.55655
SETD1A SET domain containing 1A 1.5536
CLIP1 CAP-GLY domain containing linker protein 1 1.55245
QKI QKI, KH domain containing, RNA binding 1.55164
ADAM10 ADAM metallopeptidase domain 10 1.55108
DBP D site of albumin promoter (albumin D-box) binding protein 1.54809
ALDOC aldolase C, fructose-bisphosphate 1.54354
FLCN folliculin 1.54348
CHI3L2 chitinase 3-like 2 1.54292
HEXIM1 hexamethylene bis-acetamide inducible 1 1.53979
NXT1 nuclear transport factor 2-like export factor 1 1.53912
PRKY protein kinase, Y-linked, pseudogene 1.53599
ARL4C ADP-ribosylation factor-like 4C 1.531
RNF41 ring finger protein 41, E3 ubiquitin protein ligase 1.52443
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 1.51941
CAMK1 calcium/calmodulin-dependent protein kinase I 1.51527
DLG4 discs, large homolog 4 (Drosophila) 1.50906
PTMA prothymosin, alpha 1.50745
DUSP4 dual specificity phosphatase 4 1.5016
SLC35F5 solute carrier family 35, member F5 1.49853
TACC2 transforming, acidic coiled-coil containing protein 2 1.4972
KANK3 KN motif and ankyrin repeat domains 3 1.49365
DHRS2 dehydrogenase/reductase (SDR family) member 2 1.48788
HSPA4L heat shock 70kDa protein 4-like 1.48479
ALLC allantoicase 1.48179
PFN1 profilin 1 1.48154
PLEKHA4 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 1.47486
METRN meteorin, glial cell differentiation regulator 1.47215
HBA1 hemoglobin, alpha 1 1.4716
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7 1.46993
ESRRB estrogen-related receptor beta 1.46983
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 1.4653
ADCK4 aarF domain containing kinase 4 1.46188
EDDM3B epididymal protein 3B 1.46046
TREH trehalase (brush-border membrane glycoprotein) 1.4569
THBD thrombomodulin 1.45409
BCKDK branched chain ketoacid dehydrogenase kinase 1.44532
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha 1.43256
METTL21B methyltransferase like 21B 1.43237
TCF25 transcription factor 25 (basic helix-loop-helix) 1.43064
ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) 1.42539
TEAD4 TEA domain family member 4 1.42162
AHNAK AHNAK nucleoprotein 1.42143
RPS9 ribosomal protein S9 1.41873
ASMT acetylserotonin O-methyltransferase 1.41777

low expression

Symbol Name Standardized Value
MGST3 microsomal glutathione S-transferase 3 -3.53692
PAWR PRKC, apoptosis, WT1, regulator -3.3912
JUNB jun B proto-oncogene -3.25057
NDUFC2 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa -3.09955
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) -3.01547
RAP2A RAP2A, member of RAS oncogene family -2.87783
IER3 immediate early response 3 -2.87319
LITAF lipopolysaccharide-induced TNF factor -2.85554
UBXN8 UBX domain protein 8 -2.74974
CLCN3 chloride channel, voltage-sensitive 3 -2.65312
OPN3 opsin 3 -2.58443
ADM adrenomedullin -2.54346
RAD1 RAD1 checkpoint DNA exonuclease -2.49945
GLRX glutaredoxin (thioltransferase) -2.44274
ARMCX3 armadillo repeat containing, X-linked 3 -2.43958
PDLIM1 PDZ and LIM domain 1 -2.40165
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta -2.37533
PLAGL1 pleiomorphic adenoma gene-like 1 -2.3518
LTBP3 latent transforming growth factor beta binding protein 3 -2.32168
CAB39 calcium binding protein 39 -2.29936
DCN decorin -2.29493
RNF5 ring finger protein 5, E3 ubiquitin protein ligase -2.26065
SQLE squalene epoxidase -2.24042
SLCO1A2 solute carrier organic anion transporter family, member 1A2 -2.19665
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 -2.18894
TRIB3 tribbles pseudokinase 3 -2.18303
TRIM13 tripartite motif containing 13 -2.18117
SETMAR SET domain and mariner transposase fusion gene -2.15983
H2AFY H2A histone family, member Y -2.15696
PLAU plasminogen activator, urokinase -2.14656
APH1B APH1B gamma secretase subunit -2.13429
TXNDC9 thioredoxin domain containing 9 -2.13197
HDHD1 haloacid dehalogenase-like hydrolase domain containing 1 -2.1181
AP1G2 adaptor-related protein complex 1, gamma 2 subunit -2.11617
SMC6 structural maintenance of chromosomes 6 -2.08303
ULK2 unc-51 like autophagy activating kinase 2 -2.06313
GALK1 galactokinase 1 -2.05674
ZNF518A zinc finger protein 518A -2.05435
ADD3 adducin 3 (gamma) -2.05204
FAM32A family with sequence similarity 32, member A -2.04233
CCDC106 coiled-coil domain containing 106 -2.03465
LAIR2 leukocyte-associated immunoglobulin-like receptor 2 -2.03414
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -2.03144
EPB41L1 erythrocyte membrane protein band 4.1-like 1 -2.0272
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 -2.02153
ZFP36 ZFP36 ring finger protein -2.01835
MAP3K12 mitogen-activated protein kinase kinase kinase 12 -2.01306
PRRC2C proline-rich coiled-coil 2C -2.01139
DYNLT3 dynein, light chain, Tctex-type 3 -2.00498
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria -2.00093
TTC13 tetratricopeptide repeat domain 13 -1.99312
ARHGAP29 Rho GTPase activating protein 29 -1.99112
PEX13 peroxisomal biogenesis factor 13 -1.98835
HYI hydroxypyruvate isomerase (putative) -1.98688
MORC4 MORC family CW-type zinc finger 4 -1.97483
CCDC92 coiled-coil domain containing 92 -1.97322
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 -1.97294
HOXB9 homeobox B9 -1.96653
NABP1 nucleic acid binding protein 1 -1.95551
MYO1B myosin IB -1.95392
RFPL1S RFPL1 antisense RNA 1 -1.94975
PLP2 proteolipid protein 2 (colonic epithelium-enriched) -1.93077
HRH1 histamine receptor H1 -1.92573
RPUSD2 RNA pseudouridylate synthase domain containing 2 -1.92131
ZNF223 zinc finger protein 223 -1.91309
JARID2 jumonji, AT rich interactive domain 2 -1.91193
MGA MGA, MAX dimerization protein -1.90738
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 -1.90206
MCAT malonyl CoA:ACP acyltransferase (mitochondrial) -1.89614
CD9 CD9 molecule -1.89034
COL5A2 collagen, type V, alpha 2 -1.88727
CEP162 centrosomal protein 162kDa -1.88546
NVL nuclear VCP-like -1.87016
ZNF140 zinc finger protein 140 -1.86017
IFI30 interferon, gamma-inducible protein 30 -1.85118
BMP2 bone morphogenetic protein 2 -1.84112
OSBPL9 oxysterol binding protein-like 9 -1.8317
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 -1.81991
NEU1 sialidase 1 (lysosomal sialidase) -1.79965
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II -1.79328
HOXC11 homeobox C11 -1.79195
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like -1.79099
XIST X inactive specific transcript (non-protein coding) -1.78575
TMEM185B transmembrane protein 185B -1.76895
KIAA0753 KIAA0753 -1.76684
NLRX1 NLR family member X1 -1.75521
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 -1.74677
FUZ fuzzy planar cell polarity protein -1.73967
SYNC syncoilin, intermediate filament protein -1.72102
CASP3 caspase 3, apoptosis-related cysteine peptidase -1.7196
BLVRA biliverdin reductase A -1.71468
SMAD5 SMAD family member 5 -1.71284
SLC38A1 solute carrier family 38, member 1 -1.71213
ZNF528 zinc finger protein 528 -1.71064
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 -1.70536
STOML1 stomatin (EPB72)-like 1 -1.696
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 -1.69105
RIMS3 regulating synaptic membrane exocytosis 3 -1.68998
FEM1B fem-1 homolog b (C. elegans) -1.67667
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase -1.67451
PITX2 paired-like homeodomain 2 -1.67169
SLC22A14 solute carrier family 22, member 14 -1.67089
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis) -1.66473
UBE2L6 ubiquitin-conjugating enzyme E2L 6 -1.66312
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 -1.65589
IGFBP6 insulin-like growth factor binding protein 6 -1.63729
BCAT1 branched chain amino-acid transaminase 1, cytosolic -1.63298
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 -1.62977
RAB31 RAB31, member RAS oncogene family -1.6256
GCA grancalcin, EF-hand calcium binding protein -1.62546
IFNA2 interferon, alpha 2 -1.62385
PRSS50 protease, serine, 50 -1.59829
KLF7 Kruppel-like factor 7 (ubiquitous) -1.595
ADORA2B adenosine A2b receptor -1.59323
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 -1.5737
H1F0 H1 histone family, member 0 -1.5726
ARHGAP24 Rho GTPase activating protein 24 -1.56371
NCALD neurocalcin delta -1.55886
SPCS3 signal peptidase complex subunit 3 homolog (S. cerevisiae) -1.55679
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 -1.5553
LCP1 lymphocyte cytosolic protein 1 (L-plastin) -1.55312
TSC22D3 TSC22 domain family, member 3 -1.54441
PALB2 partner and localizer of BRCA2 -1.54375
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 -1.53895
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha -1.53852
ZNF675 zinc finger protein 675 -1.53839
IRF7 interferon regulatory factor 7 -1.53448
SORT1 sortilin 1 -1.53411
IL11 interleukin 11 -1.53139
RLN1 relaxin 1 -1.5252
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) -1.51954
POLR2G polymerase (RNA) II (DNA directed) polypeptide G -1.51943
LRRC16A leucine rich repeat containing 16A -1.5166
NID1 nidogen 1 -1.5155
NRP2 neuropilin 2 -1.51398
UPK3B uroplakin 3B -1.50925
COL6A2 collagen, type VI, alpha 2 -1.50723
DBN1 drebrin 1 -1.5053
SFXN3 sideroflexin 3 -1.49428
VWA1 von Willebrand factor A domain containing 1 -1.49407
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -1.48477
DARS2 aspartyl-tRNA synthetase 2, mitochondrial -1.48473
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B -1.48452
ADGRE5 adhesion G protein-coupled receptor E5 -1.47912
RIT1 Ras-like without CAAX 1 -1.4771
NNMT nicotinamide N-methyltransferase -1.47704
FLI1 Fli-1 proto-oncogene, ETS transcription factor -1.47476
MAP1A microtubule-associated protein 1A -1.47444
ANKRD49 ankyrin repeat domain 49 -1.47414
WWC3 WWC family member 3 -1.46878
MSLN mesothelin -1.46142
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 -1.46059
ZNF552 zinc finger protein 552 -1.45907
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa -1.45713
KLHDC3 kelch domain containing 3 -1.45484
MOCS1 molybdenum cofactor synthesis 1 -1.4492
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 -1.43884
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 -1.42967
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) -1.42822
IGFBP4 insulin-like growth factor binding protein 4 -1.42227
MARCKS myristoylated alanine-rich protein kinase C substrate -1.42004
ANAPC13 anaphase promoting complex subunit 13 -1.41984
CLMN calmin (calponin-like, transmembrane) -1.41842