NCI-N87 Gene Set

Dataset COSMIC Cell Line Gene Mutation Profiles
Category genomics
Type cell line
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Genes

403 genes mutated in the NCI-N87 cell line from the COSMIC Cell Line Gene Mutation Profiles dataset.

Symbol Name
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4
ABCA6 ATP-binding cassette, sub-family A (ABC1), member 6
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11
ABI3BP ABI family, member 3 (NESH) binding protein
ACBD7 acyl-CoA binding domain containing 7
ACD adrenocortical dysplasia homolog (mouse)
ACSS2 acyl-CoA synthetase short-chain family member 2
ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif, 18
ADCY5 adenylate cyclase 5
AEN apoptosis enhancing nuclease
AGFG1 ArfGAP with FG repeats 1
AHNAK2 AHNAK nucleoprotein 2
AK5 adenylate kinase 5
ALDH8A1 aldehyde dehydrogenase 8 family, member A1
AMER3 APC membrane recruitment protein 3
ANAPC2 anaphase promoting complex subunit 2
ANGPT1 angiopoietin 1
ANKRD36C ankyrin repeat domain 36C
ANKRD60 ankyrin repeat domain 60
ANO7 anoctamin 7
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
APOB apolipoprotein B
APOL1 apolipoprotein L, 1
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
AQP12B aquaporin 12B
ARHGAP22 Rho GTPase activating protein 22
ARHGAP35 Rho GTPase activating protein 35
ARL13B ADP-ribosylation factor-like 13B
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ATF7IP activating transcription factor 7 interacting protein
ATP10B ATPase, class V, type 10B
ATP8B3 ATPase, aminophospholipid transporter, class I, type 8B, member 3
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
AUTS2 autism susceptibility candidate 2
B4GALNT2 beta-1,4-N-acetyl-galactosaminyl transferase 2
BAHCC1 BAH domain and coiled-coil containing 1
BLOC1S5 biogenesis of lysosomal organelles complex-1, subunit 5, muted
BMP15 bone morphogenetic protein 15
BNC1 basonuclin 1
BRD2 bromodomain containing 2
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CAPN3 calpain 3, (p94)
CARD16 caspase recruitment domain family, member 16
CCDC33 coiled-coil domain containing 33
CCDC8 coiled-coil domain containing 8
CCDC87 coiled-coil domain containing 87
CCHCR1 coiled-coil alpha-helical rod protein 1
CDC23 cell division cycle 23
CDH15 cadherin 15, type 1, M-cadherin (myotubule)
CDH7 cadherin 7, type 2
CDHR3 cadherin-related family member 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDR1 cerebellar degeneration-related protein 1, 34kDa
CECR5 cat eye syndrome chromosome region, candidate 5
CEL carboxyl ester lipase
CEMIP cell migration inducing protein, hyaluronan binding
CEP128 centrosomal protein 128kDa
CES2 carboxylesterase 2
CFAP36 cilia and flagella associated protein 36
CHEK2 checkpoint kinase 2
CIAO1 cytosolic iron-sulfur assembly component 1
CIT citron rho-interacting serine/threonine kinase
CLEC4E C-type lectin domain family 4, member E
CLTCL1 clathrin, heavy chain-like 1
CNBD1 cyclic nucleotide binding domain containing 1
CNGB3 cyclic nucleotide gated channel beta 3
CNN1 calponin 1, basic, smooth muscle
CNTLN centlein, centrosomal protein
CNTNAP3B contactin associated protein-like 3B
COL19A1 collagen, type XIX, alpha 1
COL5A1 collagen, type V, alpha 1
CORIN corin, serine peptidase
CORO2B coronin, actin binding protein, 2B
CSMD1 CUB and Sushi multiple domains 1
CTNNA2 catenin (cadherin-associated protein), alpha 2
CTU2 cytosolic thiouridylase subunit 2 homolog (S. pombe)
CUEDC1 CUE domain containing 1
CYP2A13 cytochrome P450, family 2, subfamily A, polypeptide 13
DCDC2 doublecortin domain containing 2
DCHS2 dachsous cadherin-related 2
DCLRE1B DNA cross-link repair 1B
DDX12P DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 12, pseudogene
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
DEFB1 defensin, beta 1
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila)
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DNAH1 dynein, axonemal, heavy chain 1
DNAH17 dynein, axonemal, heavy chain 17
DOCK8 dedicator of cytokinesis 8
DTHD1 death domain containing 1
DTX2 deltex 2, E3 ubiquitin ligase
DYSF dysferlin
EDIL3 EGF-like repeats and discoidin I-like domains 3
EGF epidermal growth factor
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
EML5 echinoderm microtubule associated protein like 5
ENAM enamelin
EPHA7 EPH receptor A7
EPHA8 EPH receptor A8
EPPK1 epiplakin 1
ERBB2 erb-b2 receptor tyrosine kinase 2
EVC Ellis van Creveld protein
EVPL envoplakin
FAM102A family with sequence similarity 102, member A
FAM109B family with sequence similarity 109, member B
FAM71C family with sequence similarity 71, member C
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FCHSD2 FCH and double SH3 domains 2
FLG filaggrin
FLOT1 flotillin 1
FNDC1 fibronectin type III domain containing 1
FOXR1 forkhead box R1
FRG1 FSHD region gene 1
FRG1B FSHD region gene 1 family, member B
FXR2 fragile X mental retardation, autosomal homolog 2
GALNT8 polypeptide N-acetylgalactosaminyltransferase 8
GALT galactose-1-phosphate uridylyltransferase
GAS2L3 growth arrest-specific 2 like 3
GBA2 glucosidase, beta (bile acid) 2
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GCDH glutaryl-CoA dehydrogenase
GFM2 G elongation factor, mitochondrial 2
GLB1L galactosidase, beta 1-like
GLRB glycine receptor, beta
GMPPA GDP-mannose pyrophosphorylase A
GON4L gon-4-like (C. elegans)
GPN1 GPN-loop GTPase 1
GPR108 G protein-coupled receptor 108
GPR176 G protein-coupled receptor 176
GPR63 G protein-coupled receptor 63
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRM6 glutamate receptor, metabotropic 6
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HELB helicase (DNA) B
HHAT hedgehog acyltransferase
HIST2H3PS2 histone cluster 2, H3, pseudogene 2
HK2 hexokinase 2
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-E major histocompatibility complex, class I, E
HPX hemopexin
HRNR hornerin
HSPG2 heparan sulfate proteoglycan 2
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
ICE1 interactor of little elongation complex ELL subunit 1
IFT172 intraflagellar transport 172
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1
IL2 interleukin 2
INCENP inner centromere protein antigens 135/155kDa
ING3 inhibitor of growth family, member 3
INTS2 integrator complex subunit 2
IRX6 iroquois homeobox 6
ITGA7 integrin, alpha 7
ITGA8 integrin, alpha 8
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
JAKMIP3 Janus kinase and microtubule interacting protein 3
JUP junction plakoglobin
KCNH4 potassium channel, voltage gated eag related subfamily H, member 4
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
KCTD20 potassium channel tetramerization domain containing 20
KCTD9 potassium channel tetramerization domain containing 9
KDM6B lysine (K)-specific demethylase 6B
KIAA1671 KIAA1671
KIF1A kinesin family member 1A
KIF24 kinesin family member 24
KIF2B kinesin family member 2B
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2
KLRG1 killer cell lectin-like receptor subfamily G, member 1
KMT2D lysine (K)-specific methyltransferase 2D
KRT15 keratin 15, type I
KRT4 keratin 4, type II
KRT78 keratin 78, type II
KRT8P11 keratin 8 pseudogene 11
KRTAP22-2 keratin associated protein 22-2
KRTAP4-4 keratin associated protein 4-4
KRTAP4-6 keratin associated protein 4-6
LCN9 lipocalin 9
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LPIN1 lipin 1
LRIT3 leucine-rich repeat, immunoglobulin-like and transmembrane domains 3
LY75 lymphocyte antigen 75
MAATS1 MYCBP-associated, testis expressed 1
MAG myelin associated glycoprotein
MAP1A microtubule-associated protein 1A
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MC3R melanocortin 3 receptor
MCM8 minichromosome maintenance complex component 8
MDC1 mediator of DNA-damage checkpoint 1
MDM1 Mdm1 nuclear protein homolog (mouse)
MED1 mediator complex subunit 1
MED24 mediator complex subunit 24
MEF2C myocyte enhancer factor 2C
MERTK MER proto-oncogene, tyrosine kinase
MICU3 mitochondrial calcium uptake family, member 3
MKI67 marker of proliferation Ki-67
MRGPRX1 MAS-related GPR, member X1
MRPL18 mitochondrial ribosomal protein L18
MRPL30 mitochondrial ribosomal protein L30
MSH6 mutS homolog 6
MTIF2 mitochondrial translational initiation factor 2
MTMR2 myotubularin related protein 2
MTUS1 microtubule associated tumor suppressor 1
MUC12 mucin 12, cell surface associated
MUC16 mucin 16, cell surface associated
MUC4 mucin 4, cell surface associated
MUC6 mucin 6, oligomeric mucus/gel-forming
MUC7 mucin 7, secreted
MYH11 myosin, heavy chain 11, smooth muscle
MYH6 myosin, heavy chain 6, cardiac muscle, alpha
MYO10 myosin X
MYO3A myosin IIIA
MYO7B myosin VIIB
MYOF myoferlin
NALCN sodium leak channel, non selective
NANOS3 nanos homolog 3 (Drosophila)
NBPF10 neuroblastoma breakpoint family, member 10
NCAPD3 non-SMC condensin II complex, subunit D3
NCAPG non-SMC condensin I complex, subunit G
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NFU1 NFU1 iron-sulfur cluster scaffold
NID2 nidogen 2 (osteonidogen)
NLRP12 NLR family, pyrin domain containing 12
NLRP3 NLR family, pyrin domain containing 3
NLRP5 NLR family, pyrin domain containing 5
NLRP7 NLR family, pyrin domain containing 7
NME9 NME/NM23 family member 9
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae)
NOTCH2NL notch 2 N-terminal like
NOV nephroblastoma overexpressed
NPAS2 neuronal PAS domain protein 2
NPAS3 neuronal PAS domain protein 3
NPC1 Niemann-Pick disease, type C1
NPFFR2 neuropeptide FF receptor 2
NPY4R neuropeptide Y receptor Y4
NR2E3 nuclear receptor subfamily 2, group E, member 3
NRXN1 neurexin 1
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3
NUP43 nucleoporin 43kDa
OBP2A odorant binding protein 2A
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
OLFML2A olfactomedin-like 2A
OR10G8 olfactory receptor, family 10, subfamily G, member 8
OR2T2 olfactory receptor, family 2, subfamily T, member 2
OR4D11 olfactory receptor, family 4, subfamily D, member 11
OR4M1 olfactory receptor, family 4, subfamily M, member 1
OR4P4 olfactory receptor, family 4, subfamily P, member 4
OR51H1 olfactory receptor, family 51, subfamily H, member 1
OR5D3P olfactory receptor, family 5, subfamily D, member 3 pseudogene
OR6F1 olfactory receptor, family 6, subfamily F, member 1
OTOG otogelin
P2RY13 purinergic receptor P2Y, G-protein coupled, 13
PARP6 poly (ADP-ribose) polymerase family, member 6
PASK PAS domain containing serine/threonine kinase
PCDH11Y protocadherin 11 Y-linked
PCDHGA12 protocadherin gamma subfamily A, 12
PCDHGB2 protocadherin gamma subfamily B, 2
PCLO piccolo presynaptic cytomatrix protein
PCNT pericentrin
PCSK7 proprotein convertase subtilisin/kexin type 7
PDE4DIP phosphodiesterase 4D interacting protein
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2
PDZD2 PDZ domain containing 2
PEG3 paternally expressed 3
PGM2L1 phosphoglucomutase 2-like 1
PHYKPL 5-phosphohydroxy-L-lysine phospho-lyase
PKD1L2 polycystic kidney disease 1-like 2 (gene/pseudogene)
PKLR pyruvate kinase, liver and RBC
PKP2 plakophilin 2
PLG plasminogen
PLXNB2 plexin B2
POTEH POTE ankyrin domain family, member H
PRG4 proteoglycan 4
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSORS1C1 psoriasis susceptibility 1 candidate 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PTPRN protein tyrosine phosphatase, receptor type, N
PTRH1 peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae)
PXMP4 peroxisomal membrane protein 4, 24kDa
PYGO1 pygopus family PHD finger 1
RBM17 RNA binding motif protein 17
RBM19 RNA binding motif protein 19
RBM20 RNA binding motif protein 20
RC3H1 ring finger and CCCH-type domains 1
RELN reelin
RGPD8 RANBP2-like and GRIP domain containing 8
RIC8A RIC8 guanine nucleotide exchange factor A
RIF1 replication timing regulatory factor 1
RIMKLB ribosomal modification protein rimK-like family member B
RNF214 ring finger protein 214
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila)
RP1L1 retinitis pigmentosa 1-like 1
RPE65 retinal pigment epithelium-specific protein 65kDa
RPS23 ribosomal protein S23
SAMD4B sterile alpha motif domain containing 4B
SBNO1 strawberry notch homolog 1 (Drosophila)
SCML4 sex comb on midleg-like 4 (Drosophila)
SCN2A sodium channel, voltage gated, type II alpha subunit
SCYL2 SCY1-like 2 (S. cerevisiae)
SDK1 sidekick cell adhesion molecule 1
SDK2 sidekick cell adhesion molecule 2
SEC14L1 SEC14-like 1 (S. cerevisiae)
SEC31A SEC31 homolog A (S. cerevisiae)
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SGCE sarcoglycan, epsilon
SHCBP1 SHC SH2-domain binding protein 1
SHH sonic hedgehog
SIK3 SIK family kinase 3
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC2A14 solute carrier family 2 (facilitated glucose transporter), member 14
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC2A7 solute carrier family 2 (facilitated glucose transporter), member 7
SLC39A5 solute carrier family 39 (zinc transporter), member 5
SLC45A1 solute carrier family 45, member 1
SLC45A4 solute carrier family 45, member 4
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SLC7A13 solute carrier family 7 (anionic amino acid transporter), member 13
SLCO4C1 solute carrier organic anion transporter family, member 4C1
SLIT3 slit homolog 3 (Drosophila)
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
SNX5 sorting nexin 5
SOCS4 suppressor of cytokine signaling 4
SP1 Sp1 transcription factor
SSBP2 single-stranded DNA binding protein 2
STARD9 StAR-related lipid transfer (START) domain containing 9
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae)
SUSD4 sushi domain containing 4
SYNE1 spectrin repeat containing, nuclear envelope 1
TBC1D21 TBC1 domain family, member 21
TBPL2 TATA box binding protein like 2
TCHP trichoplein, keratin filament binding
TCOF1 Treacher Collins-Franceschetti syndrome 1
TCTE3 t-complex-associated-testis-expressed 3
TCTN2 tectonic family member 2
TDRD12 tudor domain containing 12
TEAD4 TEA domain family member 4
TG thyroglobulin
TIGD6 tigger transposable element derived 6
TIGD7 tigger transposable element derived 7
TMC3 transmembrane channel-like 3
TMEM102 transmembrane protein 102
TMEM132A transmembrane protein 132A
TMEM67 transmembrane protein 67
TMPRSS11E transmembrane protease, serine 11E
TMPRSS11F transmembrane protease, serine 11F
TOMM20L translocase of outer mitochondrial membrane 20 homolog (yeast)-like
TOPBP1 topoisomerase (DNA) II binding protein 1
TP53 tumor protein p53
TPI1 triosephosphate isomerase 1
TRADD TNFRSF1A-associated via death domain
TRAK1 trafficking protein, kinesin binding 1
TRIM35 tripartite motif containing 35
TRIM41 tripartite motif containing 41
TRIM42 tripartite motif containing 42
TRIM49C tripartite motif containing 49C
TRIML2 tripartite motif family-like 2
TSC22D4 TSC22 domain family, member 4
TSPEAR thrombospondin-type laminin G domain and EAR repeats
TTC29 tetratricopeptide repeat domain 29
TTN titin
TXNDC15 thioredoxin domain containing 15
TXNDC2 thioredoxin domain containing 2 (spermatozoa)
UFL1 UFM1-specific ligase 1
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7
USP41 ubiquitin specific peptidase 41
USP44 ubiquitin specific peptidase 44
VARS valyl-tRNA synthetase
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae)
VTA1 vesicle (multivesicular body) trafficking 1
VWA8 von Willebrand factor A domain containing 8
VWDE von Willebrand factor D and EGF domains
WDFY4 WDFY family member 4
WDHD1 WD repeat and HMG-box DNA binding protein 1
WDR62 WD repeat domain 62
XDH xanthine dehydrogenase
ZBTB22 zinc finger and BTB domain containing 22
ZEB2 zinc finger E-box binding homeobox 2
ZFAND6 zinc finger, AN1-type domain 6
ZFHX3 zinc finger homeobox 3
ZFPM2 zinc finger protein, FOG family member 2
ZIM2 zinc finger, imprinted 2
ZMYM2 zinc finger, MYM-type 2
ZNF417 zinc finger protein 417
ZNF433 zinc finger protein 433
ZNF507 zinc finger protein 507
ZNF516 zinc finger protein 516
ZNF768 zinc finger protein 768
ZNF804A zinc finger protein 804A
ZNF891 zinc finger protein 891
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1