NCI-H929 Gene Set

Dataset COSMIC Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description Human multiple myeloma cell line; established from the pleural effusion of a 62-year-old white woman with myeloma (IgAkappa) at relapse. (BRENDA Tissue and Enzyme Source Ontology, BTO_0002416)
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376 genes mutated in the NCI-H929 cell line from the COSMIC Cell Line Gene Mutation Profiles dataset.

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1
ACAN aggrecan
ACOT8 acyl-CoA thioesterase 8
ACSM2B acyl-CoA synthetase medium-chain family member 2B
ADAMTS10 ADAM metallopeptidase with thrombospondin type 1 motif, 10
ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif, 18
ADCY10 adenylate cyclase 10 (soluble)
ADCY4 adenylate cyclase 4
ADGRB2 adhesion G protein-coupled receptor B2
ADGRB3 adhesion G protein-coupled receptor B3
AGO2 argonaute RISC catalytic component 2
AHNAK2 AHNAK nucleoprotein 2
ANGPT1 angiopoietin 1
ANK2 ankyrin 2, neuronal
ANO1 anoctamin 1, calcium activated chloride channel
APOBR apolipoprotein B receptor
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18
ARID1A AT rich interactive domain 1A (SWI-like)
ATG4C autophagy related 4C, cysteine peptidase
ATM ATM serine/threonine kinase
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
ATP7A ATPase, Cu++ transporting, alpha polypeptide
ATR ATR serine/threonine kinase
ATXN7L1 ataxin 7-like 1
BCO1 beta-carotene oxygenase 1
BCOR BCL6 corepressor
BCR breakpoint cluster region
BNC2 basonuclin 2
BRCA2 breast cancer 2, early onset
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CALB1 calbindin 1, 28kDa
CALY calcyon neuron-specific vesicular protein
CANX calnexin
CARTPT CART prepropeptide
CASS4 Cas scaffolding protein family member 4
CBX2 chromobox homolog 2
CCDC38 coiled-coil domain containing 38
CD320 CD320 molecule
CD3EAP CD3e molecule, epsilon associated protein
CDC20B cell division cycle 20B
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3
CEP104 centrosomal protein 104kDa
CEP350 centrosomal protein 350kDa
CERK ceramide kinase
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHIT1 chitinase 1 (chitotriosidase)
CHN1 chimerin 1
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
CLASP1 cytoplasmic linker associated protein 1
CNGB3 cyclic nucleotide gated channel beta 3
CNN1 calponin 1, basic, smooth muscle
CNTN2 contactin 2 (axonal)
CNTNAP5 contactin associated protein-like 5
COL18A1 collagen, type XVIII, alpha 1
COL6A2 collagen, type VI, alpha 2
COL6A5 collagen, type VI, alpha 5
COL9A1 collagen, type IX, alpha 1
COLGALT1 collagen beta(1-O)galactosyltransferase 1
COQ10B coenzyme Q10 homolog B (S. cerevisiae)
CPQ carboxypeptidase Q
CPSF3 cleavage and polyadenylation specific factor 3, 73kDa
CR2 complement component (3d/Epstein Barr virus) receptor 2
CSMD1 CUB and Sushi multiple domains 1
CSMD2 CUB and Sushi multiple domains 2
CSMD3 CUB and Sushi multiple domains 3
CSNK1G1 casein kinase 1, gamma 1
CTTNBP2 cortactin binding protein 2
CXCL16 chemokine (C-X-C motif) ligand 16
DCN decorin
DDN dendrin
DDO D-aspartate oxidase
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DEPDC7 DEP domain containing 7
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila)
DMBT1 deleted in malignant brain tumors 1
DNAH1 dynein, axonemal, heavy chain 1
DNAH17 dynein, axonemal, heavy chain 17
DNAH2 dynein, axonemal, heavy chain 2
DNAH3 dynein, axonemal, heavy chain 3
DNAH8 dynein, axonemal, heavy chain 8
DOCK4 dedicator of cytokinesis 4
DPP9 dipeptidyl-peptidase 9
DPYD dihydropyrimidine dehydrogenase
DPYSL4 dihydropyrimidinase-like 4
DSP desmoplakin
DVL2 dishevelled segment polarity protein 2
DZIP3 DAZ interacting zinc finger protein 3
ECHDC2 enoyl CoA hydratase domain containing 2
EFCAB6 EF-hand calcium binding domain 6
EFNA3 ephrin-A3
ELMO3 engulfment and cell motility 3
EPB41L3 erythrocyte membrane protein band 4.1-like 3
EPB41L4A erythrocyte membrane protein band 4.1 like 4A
EPHA5 EPH receptor A5
EPPK1 epiplakin 1
EYA4 EYA transcriptional coactivator and phosphatase 4
F8 coagulation factor VIII, procoagulant component
FAAH2 fatty acid amide hydrolase 2
FAM175A family with sequence similarity 175, member A
FAM46C family with sequence similarity 46, member C
FAM47E family with sequence similarity 47, member E
FAM65C family with sequence similarity 65, member C
FAM90A20P putative protein FAM90A20
FAN1 FANCD2/FANCI-associated nuclease 1
FCHSD1 FCH and double SH3 domains 1
FGD5 FYVE, RhoGEF and PH domain containing 5
FIBIN fin bud initiation factor homolog (zebrafish)
FMN2 formin 2
FOCAD focadhesin
FOXC1 forkhead box C1
FREM1 FRAS1 related extracellular matrix 1
FRG2 FSHD region gene 2
FSCB fibrous sheath CABYR binding protein
GCC2 GRIP and coiled-coil domain containing 2
GNRHR2 gonadotropin-releasing hormone (type 2) receptor 2, pseudogene
GPATCH4 G patch domain containing 4
GPATCH8 G patch domain containing 8
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
GRHPR glyoxylate reductase/hydroxypyruvate reductase
GSTM5 glutathione S-transferase mu 5
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
GYS1 glycogen synthase 1 (muscle)
HCFC1 host cell factor C1
HEATR3 HEAT repeat containing 3
HIST1H2BL histone cluster 1, H2bl
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HMCN1 hemicentin 1
HUS1B HUS1 checkpoint homolog b (S. pombe)
HYDIN HYDIN, axonemal central pair apparatus protein
IARS isoleucyl-tRNA synthetase
ICE1 interactor of little elongation complex ELL subunit 1
IFI16 interferon, gamma-inducible protein 16
IGSF3 immunoglobulin superfamily, member 3
IGSF9B immunoglobulin superfamily, member 9B
IL22RA1 interleukin 22 receptor, alpha 1
IMPG2 interphotoreceptor matrix proteoglycan 2
INPP5K inositol polyphosphate-5-phosphatase K
INSR insulin receptor
INTS5 integrator complex subunit 5
IQCD IQ motif containing D
IRS1 insulin receptor substrate 1
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
KANK2 KN motif and ankyrin repeat domains 2
KBTBD6 kelch repeat and BTB (POZ) domain containing 6
KCNIP1 Kv channel interacting protein 1
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KDM2A lysine (K)-specific demethylase 2A
KDM5A lysine (K)-specific demethylase 5A
KIAA1210 KIAA1210
KIAA1324L KIAA1324-like
KIAA1671 KIAA1671
KIAA1841 KIAA1841
KIF1B kinesin family member 1B
KLHL25 kelch-like family member 25
KMT2D lysine (K)-specific methyltransferase 2D
KRT16 keratin 16, type I
KRTAP5-2 keratin associated protein 5-2
LCAT lecithin-cholesterol acyltransferase
LCTL lactase-like
LETM1 leucine zipper-EF-hand containing transmembrane protein 1
LOXL3 lysyl oxidase-like 3
LRPAP1 low density lipoprotein receptor-related protein associated protein 1
LRRC53 leucine rich repeat containing 53
LRRC61 leucine rich repeat containing 61
LRRCC1 leucine rich repeat and coiled-coil centrosomal protein 1
LY9 lymphocyte antigen 9
MACF1 microtubule-actin crosslinking factor 1
MAGEC1 melanoma antigen family C1
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MAP4 microtubule-associated protein 4
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha)
MCMBP minichromosome maintenance complex binding protein
MEF2D myocyte enhancer factor 2D
MEGF8 multiple EGF-like-domains 8
MEI1 meiosis inhibitor 1
METTL17 methyltransferase like 17
MFSD11 major facilitator superfamily domain containing 11
MGA MGA, MAX dimerization protein
MICB MHC class I polypeptide-related sequence B
MIF4GD MIF4G domain containing
MOGAT1 monoacylglycerol O-acyltransferase 1
MOS v-mos Moloney murine sarcoma viral oncogene homolog
MRPL53 mitochondrial ribosomal protein L53
MST1R macrophage stimulating 1 receptor
MTA3 metastasis associated 1 family, member 3
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
MTIF2 mitochondrial translational initiation factor 2
MUC4 mucin 4, cell surface associated
MXRA5 matrix-remodelling associated 5
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYCBPAP MYCBP associated protein
MYH13 myosin, heavy chain 13, skeletal muscle
MYO18A myosin XVIIIA
MYOM2 myomesin 2
NELL1 NEL-like 1 (chicken)
NFIB nuclear factor I/B
NHLRC2 NHL repeat containing 2
NISCH nischarin
NLGN4X neuroligin 4, X-linked
NLRX1 NLR family member X1
NOB1 NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
NOL8 nucleolar protein 8
NOX3 NADPH oxidase 3
NPHP4 nephronophthisis 4
NPIPB15 nuclear pore complex interacting protein family, member B15
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae)
NRAP nebulin-related anchoring protein
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NUP98 nucleoporin 98kDa
OCM oncomodulin
OLFML2A olfactomedin-like 2A
OR2T27 olfactory receptor, family 2, subfamily T, member 27
OR4D9 olfactory receptor, family 4, subfamily D, member 9
OR6B2 olfactory receptor, family 6, subfamily B, member 2
OTUD7A OTU deubiquitinase 7A
PAM peptidylglycine alpha-amidating monooxygenase
PANK4 pantothenate kinase 4
PARK7 parkinson protein 7
PAXIP1 PAX interacting (with transcription-activation domain) protein 1
PCDH17 protocadherin 17
PCDHA12 protocadherin alpha 12
PCDHB7 protocadherin beta 7
PCDHGB4 protocadherin gamma subfamily B, 4
PCP2 Purkinje cell protein 2
PDE4B phosphodiesterase 4B, cAMP-specific
PDS5A PDS5 cohesin associated factor A
PIEZO1 piezo-type mechanosensitive ion channel component 1
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PIP prolactin-induced protein
PITRM1 pitrilysin metallopeptidase 1
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive)
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLEKHA5 pleckstrin homology domain containing, family A member 5
PLP2 proteolipid protein 2 (colonic epithelium-enriched)
PLXNA1 plexin A1
PLXNA4 plexin A4
PLXNB2 plexin B2
PNMAL2 paraneoplastic Ma antigen family-like 2
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PPP2R5D protein phosphatase 2, regulatory subunit B', delta
PPT1 palmitoyl-protein thioesterase 1
PRDM13 PR domain containing 13
PRKD1 protein kinase D1
PRKD2 protein kinase D2
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRRC2C proline-rich coiled-coil 2C
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic)
RALGAPA2 Ral GTPase activating protein, alpha subunit 2 (catalytic)
RECQL5 RecQ protein-like 5
RELN reelin
RETSAT retinol saturase (all-trans-retinol 13,14-reductase)
RIPK3 receptor-interacting serine-threonine kinase 3
RNF170 ring finger protein 170
RNH1 ribonuclease/angiogenin inhibitor 1
RP1 retinitis pigmentosa 1 (autosomal dominant)
RRBP1 ribosome binding protein 1
RSG1 REM2 and RAB-like small GTPase 1
RSPH3 radial spoke 3 homolog (Chlamydomonas)
RYR2 ryanodine receptor 2 (cardiac)
SART3 squamous cell carcinoma antigen recognized by T cells 3
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SCYL1 SCY1-like 1 (S. cerevisiae)
SEC23A Sec23 homolog A (S. cerevisiae)
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SH2D5 SH2 domain containing 5
SIGLEC16 sialic acid binding Ig-like lectin 16 (gene/pseudogene)
SIGLEC7 sialic acid binding Ig-like lectin 7
SIMC1 SUMO-interacting motifs containing 1
SIN3A SIN3 transcription regulator family member A
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3
SLC14A2 solute carrier family 14 (urea transporter), member 2
SLC17A9 solute carrier family 17 (vesicular nucleotide transporter), member 9
SLC19A3 solute carrier family 19 (thiamine transporter), member 3
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
SLC35B4 solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4
SLC35F3 solute carrier family 35, member F3
SLC38A8 solute carrier family 38, member 8
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12
SLX4 SLX4 structure-specific endonuclease subunit
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SP110 SP110 nuclear body protein
SPANXD SPANX family, member D
SPATS2L spermatogenesis associated, serine-rich 2-like
SRPK2 SRSF protein kinase 2
SRSF7 serine/arginine-rich splicing factor 7
SSTR1 somatostatin receptor 1
STAB2 stabilin 2
STARD3 StAR-related lipid transfer (START) domain containing 3
STARD9 StAR-related lipid transfer (START) domain containing 9
STRIP2 striatin interacting protein 2
SULT6B1 sulfotransferase family, cytosolic, 6B, member 1
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SYNE2 spectrin repeat containing, nuclear envelope 2
SYNGAP1 synaptic Ras GTPase activating protein 1
SYNGR2 synaptogyrin 2
SYNJ1 synaptojanin 1
SYTL2 synaptotagmin-like 2
TAS2R4 taste receptor, type 2, member 4
TBC1D7 TBC1 domain family, member 7
TBX3 T-box 3
TCHH trichohyalin
TET1 tet methylcytosine dioxygenase 1
TEX15 testis expressed 15
THAP4 THAP domain containing 4
THEG theg spermatid protein
THEMIS thymocyte selection associated
THOP1 thimet oligopeptidase 1
TICAM1 toll-like receptor adaptor molecule 1
TJP1 tight junction protein 1
TLL1 tolloid-like 1
TMEM106A transmembrane protein 106A
TMEM120B transmembrane protein 120B
TMEM139 transmembrane protein 139
TMEM179 transmembrane protein 179
TMEM2 transmembrane protein 2
TMEM220 transmembrane protein 220
TMPO thymopoietin
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TNIP1 TNFAIP3 interacting protein 1
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TNRC6C trinucleotide repeat containing 6C
TNXB tenascin XB
TP53I13 tumor protein p53 inducible protein 13
TPM3 tropomyosin 3
TPPP tubulin polymerization promoting protein
TRIM21 tripartite motif containing 21
TRIM34 tripartite motif containing 34
TRIM56 tripartite motif containing 56
TRIM6-TRIM34 TRIM6-TRIM34 readthrough
TRIM71 tripartite motif containing 71, E3 ubiquitin protein ligase
TRNAU1AP tRNA selenocysteine 1 associated protein 1
TTC28 tetratricopeptide repeat domain 28
TTLL8 tubulin tyrosine ligase-like family member 8
TTN titin
UBE3D ubiquitin protein ligase E3D
UHRF1 ubiquitin-like with PHD and ring finger domains 1
UNC13C unc-13 homolog C (C. elegans)
UNC5D unc-5 homolog D (C. elegans)
UNC93A unc-93 homolog A (C. elegans)
UPB1 ureidopropionase, beta
USP49 ubiquitin specific peptidase 49
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
VAV1 vav 1 guanine nucleotide exchange factor
VWA8 von Willebrand factor A domain containing 8
WLS wntless Wnt ligand secretion mediator
WNT1 wingless-type MMTV integration site family, member 1
XIRP1 xin actin binding repeat containing 1
XPO1 exportin 1
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZBP1 Z-DNA binding protein 1
ZEB1 zinc finger E-box binding homeobox 1
ZNF157 zinc finger protein 157
ZNF232 zinc finger protein 232
ZNF236 zinc finger protein 236
ZNF257 zinc finger protein 257
ZNF426 zinc finger protein 426
ZNF454 zinc finger protein 454
ZNF550 zinc finger protein 550
ZNF608 zinc finger protein 608
ZNF724P zinc finger protein 724, pseudogene
ZNF841 zinc finger protein 841
ZSCAN29 zinc finger and SCAN domain containing 29