NCI-H847 Gene Set

Dataset Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description disease: carcinoma; classic small cell lung cancer (lung primary) (Cell Line Ontology, CLO_0008123)
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116 genes mutated in the NCI-H847 cell line from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles dataset.

Symbol Name
ADGRB1 adhesion G protein-coupled receptor B1
AEBP1 AE binding protein 1
ANK2 ankyrin 2, neuronal
ARID1A AT rich interactive domain 1A (SWI-like)
C19ORF26 chromosome 19 open reading frame 26
C1ORF106 chromosome 1 open reading frame 106
C8ORF34 chromosome 8 open reading frame 34
CCDC39 coiled-coil domain containing 39
CCDC77 coiled-coil domain containing 77
CD8B CD8b molecule
CLEC4F C-type lectin domain family 4, member F
CMIP c-Maf inducing protein
COBLL1 cordon-bleu WH2 repeat protein-like 1
DAZAP1 DAZ associated protein 1
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DMXL1 Dmx-like 1
DNHD1 dynein heavy chain domain 1
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DST dystonin
DUSP28 dual specificity phosphatase 28
EARS2 glutamyl-tRNA synthetase 2, mitochondrial
EFCAB3 EF-hand calcium binding domain 3
EMC7 ER membrane protein complex subunit 7
ERBB2IP erbb2 interacting protein
ESPNL espin-like
F2R coagulation factor II (thrombin) receptor
FAM65B family with sequence similarity 65, member B
FBXL12 F-box and leucine-rich repeat protein 12
FGFBP3 fibroblast growth factor binding protein 3
FMN2 formin 2
FOXO1 forkhead box O1
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2
GLS glutaminase
GOPC golgi-associated PDZ and coiled-coil motif containing
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
GRK4 G protein-coupled receptor kinase 4
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1
HMHA1 histocompatibility (minor) HA-1
HOOK2 hook microtubule-tethering protein 2
HOOK3 hook microtubule-tethering protein 3
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
HSPH1 heat shock 105kDa/110kDa protein 1
IFT20 intraflagellar transport 20
IGF2R insulin-like growth factor 2 receptor
IRF3 interferon regulatory factor 3
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KIAA1467 KIAA1467
KIF13A kinesin family member 13A
KMT2B lysine (K)-specific methyltransferase 2B
LARP1 La ribonucleoprotein domain family, member 1
LNPEP leucyl/cystinyl aminopeptidase
LRP1B low density lipoprotein receptor-related protein 1B
LUZP6 leucine zipper protein 6
MAPKAP1 mitogen-activated protein kinase associated protein 1
MAST3 microtubule associated serine/threonine kinase 3
MBD1 methyl-CpG binding domain protein 1
MBD6 methyl-CpG binding domain protein 6
MBTPS1 membrane-bound transcription factor peptidase, site 1
MKNK2 MAP kinase interacting serine/threonine kinase 2
MXI1 MAX interactor 1, dimerization protein
NCAPH non-SMC condensin I complex, subunit H
NFE2L1 nuclear factor, erythroid 2-like 1
NT5C3A 5'-nucleotidase, cytosolic IIIA
NT5DC2 5'-nucleotidase domain containing 2
NUP214 nucleoporin 214kDa
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDCD6 programmed cell death 6
PHF23 PHD finger protein 23
PHF3 PHD finger protein 3
PLEKHH1 pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
POU4F1 POU class 4 homeobox 1
PTEN phosphatase and tensin homolog
PTGDR2 prostaglandin D2 receptor 2
QSOX1 quiescin Q6 sulfhydryl oxidase 1
RAD50 RAD50 homolog (S. cerevisiae)
RB1 retinoblastoma 1
RRAGB Ras-related GTP binding B
SCN9A sodium channel, voltage gated, type IX alpha subunit
SHKBP1 SH3KBP1 binding protein 1
SIRT5 sirtuin 5
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
SNX27 sorting nexin family member 27
SQLE squalene epoxidase
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STK11IP serine/threonine kinase 11 interacting protein
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa
TAF1L TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like
TAL1 T-cell acute lymphocytic leukemia 1
TCF15 transcription factor 15 (basic helix-loop-helix)
TECTA tectorin alpha
TENM3 teneurin transmembrane protein 3
TFE3 transcription factor binding to IGHM enhancer 3
TMTC4 transmembrane and tetratricopeptide repeat containing 4
TP53 tumor protein p53
TRIM71 tripartite motif containing 71, E3 ubiquitin protein ligase
TRMT10A tRNA methyltransferase 10 homolog A (S. cerevisiae)
TRPA1 transient receptor potential cation channel, subfamily A, member 1
TSHZ1 teashirt zinc finger homeobox 1
USP9X ubiquitin specific peptidase 9, X-linked
UXS1 UDP-glucuronate decarboxylase 1
WRN Werner syndrome, RecQ helicase-like
WRNIP1 Werner helicase interacting protein 1
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF112 zinc finger protein 112
ZNF226 zinc finger protein 226
ZNF234 zinc finger protein 234
ZNF296 zinc finger protein 296
ZNF354B zinc finger protein 354B
ZNF496 zinc finger protein 496
ZNF516 zinc finger protein 516
ZNF592 zinc finger protein 592
ZNF805 zinc finger protein 805