NCI-H847 Gene Set

Dataset COSMIC Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description disease: carcinoma; classic small cell lung cancer (lung primary) (Cell Line Ontology, CLO_0008123)
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425 genes mutated in the NCI-H847 cell line from the COSMIC Cell Line Gene Mutation Profiles dataset.

Symbol Name
ABCA6 ATP-binding cassette, sub-family A (ABC1), member 6
ABCA9 ATP-binding cassette, sub-family A (ABC1), member 9
ABHD6 abhydrolase domain containing 6
ACAT2 acetyl-CoA acetyltransferase 2
ACSM2B acyl-CoA synthetase medium-chain family member 2B
ACTG1 actin gamma 1
ADAM19 ADAM metallopeptidase domain 19
ADAM23 ADAM metallopeptidase domain 23
ADAMDEC1 ADAM-like, decysin 1
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADCK5 aarF domain containing kinase 5
ADCY1 adenylate cyclase 1 (brain)
ADGRB1 adhesion G protein-coupled receptor B1
ADGRG3 adhesion G protein-coupled receptor G3
ADGRL2 adhesion G protein-coupled receptor L2
ADGRV1 adhesion G protein-coupled receptor V1
AEBP1 AE binding protein 1
AFF4 AF4/FMR2 family, member 4
AKR1C1 aldo-keto reductase family 1, member C1
AKR7L aldo-keto reductase family 7-like (gene/pseudogene)
ALPP alkaline phosphatase, placental
ANGPT4 angiopoietin 4
ANK2 ankyrin 2, neuronal
ANKRD27 ankyrin repeat domain 27 (VPS9 domain)
ANKRD6 ankyrin repeat domain 6
APOB apolipoprotein B
ARHGAP27 Rho GTPase activating protein 27
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARHGEF25 Rho guanine nucleotide exchange factor (GEF) 25
ARL11 ADP-ribosylation factor-like 11
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
ASB12 ankyrin repeat and SOCS box containing 12
ASTN1 astrotactin 1
ATAD3C ATPase family, AAA domain containing 3C
ATG14 autophagy related 14
ATP6V1C2 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2
BIN2 bridging integrator 2
BPGM 2,3-bisphosphoglycerate mutase
BPI bactericidal/permeability-increasing protein
BRCA1 breast cancer 1, early onset
BSPRY B-box and SPRY domain containing
C4BPA complement component 4 binding protein, alpha
C9 complement component 9
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CCDC108 coiled-coil domain containing 108
CCDC39 coiled-coil domain containing 39
CCDC40 coiled-coil domain containing 40
CCDC77 coiled-coil domain containing 77
CCDC85A coiled-coil domain containing 85A
CCKAR cholecystokinin A receptor
CCKBR cholecystokinin B receptor
CCL25 chemokine (C-C motif) ligand 25
CDH18 cadherin 18, type 2
CDHR1 cadherin-related family member 1
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CDX1 caudal type homeobox 1
CEACAM18 carcinoembryonic antigen-related cell adhesion molecule 18
CELF5 CUGBP, Elav-like family member 5
CEP135 centrosomal protein 135kDa
CFAP46 cilia and flagella associated protein 46
CFAP52 cilia and flagella associated protein 52
CIC capicua transcriptional repressor
CMIP c-Maf inducing protein
CMYA5 cardiomyopathy associated 5
COBLL1 cordon-bleu WH2 repeat protein-like 1
COL10A1 collagen, type X, alpha 1
COL11A1 collagen, type XI, alpha 1
COL12A1 collagen, type XII, alpha 1
COL14A1 collagen, type XIV, alpha 1
COL27A1 collagen, type XXVII, alpha 1
CROCC ciliary rootlet coiled-coil, rootletin
CSMD1 CUB and Sushi multiple domains 1
CSMD3 CUB and Sushi multiple domains 3
CTSK cathepsin K
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
CYP4F22 cytochrome P450, family 4, subfamily F, polypeptide 22
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1
DCBLD1 discoidin, CUB and LCCL domain containing 1
DCBLD2 discoidin, CUB and LCCL domain containing 2
DCC DCC netrin 1 receptor
DCHS2 dachsous cadherin-related 2
DCST2 DC-STAMP domain containing 2
DEFB112 defensin, beta 112
DEFB116 defensin, beta 116
DEPDC1 DEP domain containing 1
DHFR dihydrofolate reductase
DHRS2 dehydrogenase/reductase (SDR family) member 2
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DISC1 disrupted in schizophrenia 1
DMXL1 Dmx-like 1
DNAH12 dynein, axonemal, heavy chain 12
DNAH6 dynein, axonemal, heavy chain 6
DNAH9 dynein, axonemal, heavy chain 9
DNASE2B deoxyribonuclease II beta
DOCK2 dedicator of cytokinesis 2
DPF3 D4, zinc and double PHD fingers, family 3
DPYD dihydropyrimidine dehydrogenase
DSCAML1 Down syndrome cell adhesion molecule like 1
DST dystonin
DYSF dysferlin
EARS2 glutamyl-tRNA synthetase 2, mitochondrial
EFTUD2 elongation factor Tu GTP binding domain containing 2
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
ELFN2 extracellular leucine-rich repeat and fibronectin type III domain containing 2
EPHX4 epoxide hydrolase 4
ERBB2IP erbb2 interacting protein
ESPNL espin-like
EXOSC2 exosome component 2
EYS eyes shut homolog (Drosophila)
F2R coagulation factor II (thrombin) receptor
FAM135B family with sequence similarity 135, member B
FAM187B family with sequence similarity 187, member B
FAM46A family with sequence similarity 46, member A
FAM65B family with sequence similarity 65, member B
FBXO18 F-box protein, helicase, 18
FCRL1 Fc receptor-like 1
FGA fibrinogen alpha chain
FMN2 formin 2
FNDC9 fibronectin type III domain containing 9
FOLH1B folate hydrolase 1B
FOXO1 forkhead box O1
FOXP3 forkhead box P3
FUBP1 far upstream element (FUSE) binding protein 1
GABARAPL1 GABA(A) receptor-associated protein like 1
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2
GDF5 growth differentiation factor 5
GDF5OS growth differentiation factor 5 opposite strand
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GFI1 growth factor independent 1 transcription repressor
GLS glutaminase
GOLGA2 golgin A2
GOPC golgi-associated PDZ and coiled-coil motif containing
GPR132 G protein-coupled receptor 132
GPR149 G protein-coupled receptor 149
GPR151 G protein-coupled receptor 151
GPR25 G protein-coupled receptor 25
GPR39 G protein-coupled receptor 39
GRAMD3 GRAM domain containing 3
GRIA4 glutamate receptor, ionotropic, AMPA 4
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
H2AFJ H2A histone family, member J
HAPLN1 hyaluronan and proteoglycan link protein 1
HAUS2 HAUS augmin-like complex, subunit 2
HBP1 HMG-box transcription factor 1
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
HGFAC HGF activator
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HMHA1 histocompatibility (minor) HA-1
HOOK2 hook microtubule-tethering protein 2
HOOK3 hook microtubule-tethering protein 3
HOXB2 homeobox B2
HPD 4-hydroxyphenylpyruvate dioxygenase
HPS6 Hermansky-Pudlak syndrome 6
HRNR hornerin
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
HSPH1 heat shock 105kDa/110kDa protein 1
HTT huntingtin
HYDIN HYDIN, axonemal central pair apparatus protein
ICAM3 intercellular adhesion molecule 3
ICE1 interactor of little elongation complex ELL subunit 1
IFFO2 intermediate filament family orphan 2
IFI44L interferon-induced protein 44-like
IGF2R insulin-like growth factor 2 receptor
IL12RB1 interleukin 12 receptor, beta 1
ILKAP integrin-linked kinase-associated serine/threonine phosphatase
INPP5J inositol polyphosphate-5-phosphatase J
IQUB IQ motif and ubiquitin domain containing
IRF3 interferon regulatory factor 3
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KCNA10 potassium channel, voltage gated shaker related subfamily A, member 10
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNG2 potassium channel, voltage gated modifier subfamily G, member 2
KCNT1 potassium channel, sodium activated subfamily T, member 1
KDM5A lysine (K)-specific demethylase 5A
KIAA1045 KIAA1045
KIAA1217 KIAA1217
KIAA1467 KIAA1467
KIF13A kinesin family member 13A
KIF2B kinesin family member 2B
KLF4 Kruppel-like factor 4 (gut)
KLHL13 kelch-like family member 13
KRT84 keratin 84, type II
KRTAP21-3 keratin associated protein 21-3
KTN1 kinectin 1 (kinesin receptor)
L2HGDH L-2-hydroxyglutarate dehydrogenase
LAMB3 laminin, beta 3
LAPTM5 lysosomal protein transmembrane 5
LARP1 La ribonucleoprotein domain family, member 1
LBP lipopolysaccharide binding protein
LGALS8 lectin, galactoside-binding, soluble, 8
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
LNPEP leucyl/cystinyl aminopeptidase
LRP1B low density lipoprotein receptor-related protein 1B
LRRC2 leucine rich repeat containing 2
LRRC3 leucine rich repeat containing 3
LRRC7 leucine rich repeat containing 7
LRRTM2 leucine rich repeat transmembrane neuronal 2
LSR lipolysis stimulated lipoprotein receptor
LTBP2 latent transforming growth factor beta binding protein 2
MAMSTR MEF2 activating motif and SAP domain containing transcriptional regulator
MAP2K7 mitogen-activated protein kinase kinase 7
MAP3K4 mitogen-activated protein kinase kinase kinase 4
MAPKAP1 mitogen-activated protein kinase associated protein 1
MAST3 microtubule associated serine/threonine kinase 3
MBD1 methyl-CpG binding domain protein 1
MBD6 methyl-CpG binding domain protein 6
MBTPS1 membrane-bound transcription factor peptidase, site 1
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial
MEI1 meiosis inhibitor 1
METAP1 methionyl aminopeptidase 1
METTL5 methyltransferase like 5
MFSD7 major facilitator superfamily domain containing 7
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MKNK2 MAP kinase interacting serine/threonine kinase 2
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MRPS31 mitochondrial ribosomal protein S31
MTMR8 myotubularin related protein 8
MUC12 mucin 12, cell surface associated
MUC16 mucin 16, cell surface associated
MUC19 mucin 19, oligomeric
MUC4 mucin 4, cell surface associated
MXI1 MAX interactor 1, dimerization protein
MYH10 myosin, heavy chain 10, non-muscle
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic
MYL2 myosin, light chain 2, regulatory, cardiac, slow
NCAPH non-SMC condensin I complex, subunit H
NFASC neurofascin
NFE2L1 nuclear factor, erythroid 2-like 1
NLRC4 NLR family, CARD domain containing 4
NLRP4 NLR family, pyrin domain containing 4
NOTCH4 notch 4
NOTO notochord homeobox
NRG3 neuregulin 3
NT5C3A 5'-nucleotidase, cytosolic IIIA
NT5DC2 5'-nucleotidase domain containing 2
NUP210L nucleoporin 210kDa-like
NUP214 nucleoporin 214kDa
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
OMG oligodendrocyte myelin glycoprotein
OR10J3 olfactory receptor, family 10, subfamily J, member 3
OR10X1 olfactory receptor, family 10, subfamily X, member 1 (gene/pseudogene)
OR14A2 olfactory receptor, family 14, subfamily A, member 2
OR2J2 olfactory receptor, family 2, subfamily J, member 2
OR4N2 olfactory receptor, family 4, subfamily N, member 2
OR5D16 olfactory receptor, family 5, subfamily D, member 16
OR5M9 olfactory receptor, family 5, subfamily M, member 9
OR6V1 olfactory receptor, family 6, subfamily V, member 1
OR7A2P olfactory receptor, family 7, subfamily A, member 2 pseudogene
OTOGL otogelin-like
OTOP2 otopetrin 2
PARP15 poly (ADP-ribose) polymerase family, member 15
PARP4 poly (ADP-ribose) polymerase family, member 4
PAXBP1 PAX3 and PAX7 binding protein 1
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCBP1 poly(rC) binding protein 1
PCDH12 protocadherin 12
PCDH17 protocadherin 17
PCDHGB3 protocadherin gamma subfamily B, 3
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PCSK1 proprotein convertase subtilisin/kexin type 1
PDCD6 programmed cell death 6
PDE10A phosphodiesterase 10A
PDE4A phosphodiesterase 4A, cAMP-specific
PDILT protein disulfide isomerase-like, testis expressed
PHF3 PHD finger protein 3
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PLCE1 phospholipase C, epsilon 1
PLEKHH1 pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
PLXNB2 plexin B2
PLXNC1 plexin C1
PNPLA7 patatin-like phospholipase domain containing 7
POF1B premature ovarian failure, 1B
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
POLR1A polymerase (RNA) I polypeptide A, 194kDa
POLR2G polymerase (RNA) II (DNA directed) polypeptide G
PPP1R42 protein phosphatase 1, regulatory subunit 42
PPP2R2C protein phosphatase 2, regulatory subunit B, gamma
PRDM9 PR domain containing 9
PRKCG protein kinase C, gamma
PRR23A proline rich 23A
PRUNE2 prune homolog 2 (Drosophila)
PSG1 pregnancy specific beta-1-glycoprotein 1
PSG11 pregnancy specific beta-1-glycoprotein 11
PTEN phosphatase and tensin homolog
PUM1 pumilio RNA-binding family member 1
QSOX1 quiescin Q6 sulfhydryl oxidase 1
RAD21L1 RAD21-like 1 (S. pombe)
RAD50 RAD50 homolog (S. cerevisiae)
RB1 retinoblastoma 1
RBM47 RNA binding motif protein 47
RNF10 ring finger protein 10
RP1L1 retinitis pigmentosa 1-like 1
RPS21 ribosomal protein S21
RRH retinal pigment epithelium-derived rhodopsin homolog
RRP1B ribosomal RNA processing 1B
S100PBP S100P binding protein
SCG5 secretogranin V
SCN10A sodium channel, voltage gated, type X alpha subunit
SCN1A sodium channel, voltage gated, type I alpha subunit
SCN2A sodium channel, voltage gated, type II alpha subunit
SCN9A sodium channel, voltage gated, type IX alpha subunit
SCTR secretin receptor
SHANK1 SH3 and multiple ankyrin repeat domains 1
SHKBP1 SH3KBP1 binding protein 1
SIRT5 sirtuin 5
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC22A14 solute carrier family 22, member 14
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
SLC26A7 solute carrier family 26 (anion exchanger), member 7
SLC27A4 solute carrier family 27 (fatty acid transporter), member 4
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2
SLC31A1 solute carrier family 31 (copper transporter), member 1
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1
SLC5A9 solute carrier family 5 (sodium/sugar cotransporter), member 9
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SLC6A18 solute carrier family 6 (neutral amino acid transporter), member 18
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SLC9A4 solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4
SLITRK3 SLIT and NTRK-like family, member 3
SNX21 sorting nexin family member 21
SNX27 sorting nexin family member 27
SPON2 spondin 2, extracellular matrix protein
SPTA1 spectrin, alpha, erythrocytic 1
SQLE squalene epoxidase
SRRM4 serine/arginine repetitive matrix 4
SSR2 signal sequence receptor, beta (translocon-associated protein beta)
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STK11IP serine/threonine kinase 11 interacting protein
SYNGR2 synaptogyrin 2
SYNGR4 synaptogyrin 4
SYNM synemin, intermediate filament protein
SYNPO synaptopodin
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa
TAL1 T-cell acute lymphocytic leukemia 1
TAS2R39 taste receptor, type 2, member 39
TBXAS1 thromboxane A synthase 1 (platelet)
TCF15 transcription factor 15 (basic helix-loop-helix)
TCF20 transcription factor 20 (AR1)
TCP10L2 t-complex 10-like 2
TECTA tectorin alpha
TECTB tectorin beta
TENM1 teneurin transmembrane protein 1
TGM3 transglutaminase 3
THNSL2 threonine synthase-like 2 (S. cerevisiae)
TLN1 talin 1
TLR1 toll-like receptor 1
TMEM171 transmembrane protein 171
TMEM175 transmembrane protein 175
TMEM178A transmembrane protein 178A
TMEM78 transmembrane protein 78
TMEM79 transmembrane protein 79
TMPRSS15 transmembrane protease, serine 15
TMTC4 transmembrane and tetratricopeptide repeat containing 4
TNR tenascin R
TNXB tenascin XB
TONSL tonsoku-like, DNA repair protein
TOR1B torsin family 1, member B (torsin B)
TOR3A torsin family 3, member A
TP53 tumor protein p53
TRAK1 trafficking protein, kinesin binding 1
TRIM49 tripartite motif containing 49
TRIOBP TRIO and F-actin binding protein
TRMT10A tRNA methyltransferase 10 homolog A (S. cerevisiae)
TSHZ1 teashirt zinc finger homeobox 1
TSPEAR thrombospondin-type laminin G domain and EAR repeats
TSSK6 testis-specific serine kinase 6
TTN titin
TULP3 tubby like protein 3
TYMS thymidylate synthetase
UBE2O ubiquitin-conjugating enzyme E2O
ULK1 unc-51 like autophagy activating kinase 1
UNC5C unc-5 homolog C (C. elegans)
USP26 ubiquitin specific peptidase 26
USP9X ubiquitin specific peptidase 9, X-linked
UXS1 UDP-glucuronate decarboxylase 1
VCAM1 vascular cell adhesion molecule 1
VMP1 vacuole membrane protein 1
VN1R4 vomeronasal 1 receptor 4
VNN2 vanin 2
VPS13B vacuolar protein sorting 13 homolog B (yeast)
VTN vitronectin
VWF von Willebrand factor
WDR62 WD repeat domain 62
WDR64 WD repeat domain 64
WDR87 WD repeat domain 87
WIF1 WNT inhibitory factor 1
WNT6 wingless-type MMTV integration site family, member 6
WRN Werner syndrome, RecQ helicase-like
XDH xanthine dehydrogenase
XIRP2 xin actin binding repeat containing 2
XPO5 exportin 5
YLPM1 YLP motif containing 1
ZC3H13 zinc finger CCCH-type containing 13
ZIC4 Zic family member 4
ZMAT1 zinc finger, matrin-type 1
ZNF112 zinc finger protein 112
ZNF208 zinc finger protein 208
ZNF234 zinc finger protein 234
ZNF296 zinc finger protein 296
ZNF354B zinc finger protein 354B
ZNF43 zinc finger protein 43
ZNF444 zinc finger protein 444
ZNF496 zinc finger protein 496
ZNF507 zinc finger protein 507
ZNF546 zinc finger protein 546
ZNF571 zinc finger protein 571
ZNF592 zinc finger protein 592
ZNF638 zinc finger protein 638
ZNF675 zinc finger protein 675
ZNF696 zinc finger protein 696
ZNF772 zinc finger protein 772
ZNF805 zinc finger protein 805
ZNF831 zinc finger protein 831
ZSWIM6 zinc finger, SWIM-type containing 6
ZXDA zinc finger, X-linked, duplicated A