NCI-H841 Gene Set

Dataset COSMIC Cell Line Gene CNV Profiles
Category genomics
Type cell line
Description disease: carcinoma; variant small cell lung cancer (lung primary) (Cell Line Ontology, CLO_0008122)
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Genes

164 genes with high or low copy number in NCI-H841 relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.

high copy number

Symbol Name Standardized Value
GABARAP GABA(A) receptor-associated protein 4.51153
ACADVL acyl-CoA dehydrogenase, very long chain 4.51153
LRRC37B leucine rich repeat containing 37B 4.51153
TNK1 tyrosine kinase, non-receptor, 1 4.51153
SUZ12 SUZ12 polycomb repressive complex 2 subunit 4.51153
TMEM102 transmembrane protein 102 4.51153
SLC35G6 solute carrier family 35, member G6 4.51153
PLSCR3 phospholipid scramblase 3 4.51153
ZNF207 zinc finger protein 207 4.51153
ZBTB4 zinc finger and BTB domain containing 4 4.51153
TNFSF12-TNFSF13 TNFSF12-TNFSF13 readthrough 4.51153
ARGFXP2 arginine-fifty homeobox pseudogene 2 4.51153
EIF5A eukaryotic translation initiation factor 5A 4.51153
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12 4.51153
KCTD11 potassium channel tetramerization domain containing 11 4.51153
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle) 4.51153
CTDNEP1 CTD nuclear envelope phosphatase 1 4.51153
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2 4.51153
WRAP53 WD repeat containing, antisense to TP53 4.51153
SNORA48 small nucleolar RNA, H/ACA box 48 4.51153
C17ORF74 chromosome 17 open reading frame 74 4.51153
C17ORF75 chromosome 17 open reading frame 75 4.51153
CD68 CD68 molecule 4.51153
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3 4.51153
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13 4.51153
FGF11 fibroblast growth factor 11 4.51153
RHOT1 ras homolog family member T1 4.51153
TMEM95 transmembrane protein 95 4.51153
GPS2 G protein pathway suppressor 2 4.51153
MIR324 microRNA 324 4.51153
NLGN2 neuroligin 2 4.51153
NEURL4 neuralized E3 ubiquitin protein ligase 4 4.51153
ELP5 elongator acetyltransferase complex subunit 5 4.51153
PHF23 PHD finger protein 23 4.51153
SPEM1 spermatid maturation 1 4.51153
YBX2 Y box binding protein 2 4.51153
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 4.51153
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 4.51153
TMEM256 transmembrane protein 256 4.51153
RHBDL3 rhomboid, veinlet-like 3 (Drosophila) 4.51153
SH3GL1P1 SH3-domain GRB2-like 1 pseudogene 1 4.51153
SNORD10 small nucleolar RNA, C/D box 10 4.51153
DVL2 dishevelled segment polarity protein 2 4.51153
CLDN7 claudin 7 4.51153
MIR632 microRNA 632 4.51153
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 4.51153
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 4.51153
SENP3-EIF4A1 SENP3-EIF4A1 readthrough (NMD candidate) 4.51153
EFNB3 ephrin-B3 4.51153
ASGR1 asialoglycoprotein receptor 1 3.12177
ASGR2 asialoglycoprotein receptor 2 3.12177
CLEC10A C-type lectin domain family 10, member A 3.12177
LEFTY2 left-right determination factor 2 3.12177
LEFTY1 left-right determination factor 1 3.12177
MIR497HG mir-497-195 cluster host gene 3.12177
LOC100506713 3.12177
ENAH enabled homolog (Drosophila) 3.12177
ALOX12 arachidonate 12-lipoxygenase 3.12177
SLC16A13 solute carrier family 16, member 13 3.12177
H3F3A H3 histone, family 3A 3.12177
SLC16A11 solute carrier family 16, member 11 3.12177
SRP9 signal recognition particle 9kDa 3.12177
RNASEK-C17ORF49 RNASEK-C17orf49 readthrough 3.12177
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 3.12177
LBR lamin B receptor 3.12177
TMEM63A transmembrane protein 63A 3.12177
PYCR2 pyrroline-5-carboxylate reductase family, member 2 3.12177
SDE2 SDE2 telomere maintenance homolog (S. pombe) 3.12177
MIR497 microRNA 497 3.12177
H3F3AP4 H3 histone, family 3A, pseudogene 4 3.12177
ACBD3 acyl-CoA binding domain containing 3 3.12177
BCL6B B-cell CLL/lymphoma 6, member B 3.12177
DLG4 discs, large homolog 4 (Drosophila) 3.12177
DNAH14 dynein, axonemal, heavy chain 14 3.12177
LIN9 lin-9 DREAM MuvB core complex component 2.93899
MIXL1 Mix paired-like homeobox 2.93899
UTP6 UTP6, small subunit (SSU) processome component, homolog (yeast) 2.93899
PSEN2 presenilin 2 2.93899
COPRS coordinator of PRMT5, differentiation stimulator 2.93899
ITPKB inositol-trisphosphate 3-kinase B 2.76305
PARP1 poly (ADP-ribose) polymerase 1 2.76305
C1ORF95 chromosome 1 open reading frame 95 2.76305
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 2.41451
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E 2.41451
PCLO piccolo presynaptic cytomatrix protein 2.39327
KIAA1324L KIAA1324-like 2.39327
GRM3 glutamate receptor, metabotropic 3 2.36889
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1 2.35236
SNORA67 small nucleolar RNA, H/ACA box 67 2.283
DIAPH2 diaphanous-related formin 2 2.15859
RPA4 replication protein A4, 30kDa 2.15812
TP53 tumor protein p53 2.15726
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide 2.15648
SHBG sex hormone-binding globulin 2.15529
FXR2 fragile X mental retardation, autosomal homolog 2 2.15465
SAT2 spermidine/spermine N1-acetyltransferase family member 2 2.15465
DNAH2 dynein, axonemal, heavy chain 2 2.15316
SOX15 SRY (sex determining region Y)-box 15 2.15316
MPDU1 mannose-P-dolichol utilization defect 1 2.15316
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1 2.14746
APOOL apolipoprotein O-like 2.14746
FAM133A family with sequence similarity 133, member A 2.14731
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6 2.14731
SATL1 spermidine/spermine N1-acetyl transferase-like 1 2.14731
UBE2DNL ubiquitin-conjugating enzyme E2D N-terminal like (pseudogene) 2.14731
IL1RAPL2 interleukin 1 receptor accessory protein-like 2 2.14702
PCDH11X protocadherin 11 X-linked 2.14702
NAP1L3 nucleosome assembly protein 1-like 3 2.14702
TEX13A testis expressed 13A 2.14702
POU3F4 POU class 3 homeobox 4 2.14702
LOC643486 2.14664
NRK Nik related kinase 2.14664
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 2.14664
RAB40A RAB40A, member RAS oncogene family 2.14626
WBP5 WW domain binding protein 5 2.14626
TCEAL5 transcription elongation factor A (SII)-like 5 2.14626
TCEAL7 transcription elongation factor A (SII)-like 7 2.14626
BEX4 brain expressed, X-linked 4 2.14626
TCEAL1 transcription elongation factor A (SII)-like 1 2.14626
TCEAL3 transcription elongation factor A (SII)-like 3 2.14626
BEX2 brain expressed X-linked 2 2.14626
TCEAL8 transcription elongation factor A (SII)-like 8 2.14626
BEX1 brain expressed, X-linked 1 2.14626
PLP1 proteolipid protein 1 2.14626
NXF3 nuclear RNA export factor 3 2.14626
LINC00630 long intergenic non-protein coding RNA 630 2.14626
RAB9B RAB9B, member RAS oncogene family 2.14626
TMEM31 transmembrane protein 31 2.14588
RAB40AL RAB40A, member RAS oncogene family-like 2.14588
MORF4L2 mortality factor 4 like 2 2.14588
H2BFXP H2B histone family, member X, pseudogene 2.14588
TCEAL4 transcription elongation factor A (SII)-like 4 2.14588
FAM199X family with sequence similarity 199, X-linked 2.14588
GLRA4 glycine receptor, alpha 4 2.14588
TMSB15B thymosin beta 15B 2.14588
MORF4L2-AS1 MORF4L2 antisense RNA 1 2.14588
ESX1 ESX homeobox 1 2.14588
SLC25A53 solute carrier family 25, member 53 2.14588
H2BFWT H2B histone family, member W, testis-specific 2.14588
H2BFM H2B histone family, member M 2.14588
ZCCHC18 zinc finger, CCHC domain containing 18 2.14588
LOC286437 uncharacterized LOC286437 2.14588
HDX highly divergent homeobox 2.13697
PABPC5 poly(A) binding protein, cytoplasmic 5 2.13697
TGIF2LX TGFB-induced factor homeobox 2-like, X-linked 2.1368
POF1B premature ovarian failure, 1B 2.1368
ZNF711 zinc finger protein 711 2.1368
DACH2 dachshund family transcription factor 2 2.1368
CHM choroideremia (Rab escort protein 1) 2.13663
ADCK3 aarF domain containing kinase 3 2.12703
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) 2.12703
MIR1256 microRNA 1256 2.11435
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D 2.08021

low copy number

Symbol Name Standardized Value
LOC440896 uncharacterized LOC440896 -3.61078
PGM5P2 phosphoglucomutase 5 pseudogene 2 -3.57558
MTCP1 mature T-cell proliferation 1 -3.2703
CMC4 C-x(9)-C motif containing 4 -3.2703
F8 coagulation factor VIII, procoagulant component -3.2703
FUNDC2 FUN14 domain containing 2 -3.2703
BRCC3 BRCA1/BRCA2-containing complex, subunit 3 -3.2703
MIR1184-3 microRNA 1184-3 -3.12964
F8A1 coagulation factor VIII-associated 1 -3.12964
H2AFB3 H2A histone family, member B3 -3.12964
LINC00221 long intergenic non-protein coding RNA 221 -2.84895