NCI-H820 Gene Set

Dataset Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description disease: papillary adenocarci- noma (lung primary) (Cell Line Ontology, CLO_0008119)
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89 genes mutated in the NCI-H820 cell line from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles dataset.

Symbol Name
AACS acetoacetyl-CoA synthetase
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ADGRE5 adhesion G protein-coupled receptor E5
ADGRF5 adhesion G protein-coupled receptor F5
ANAPC5 anaphase promoting complex subunit 5
ANKRD11 ankyrin repeat domain 11
ARSK arylsulfatase family, member K
BAHCC1 BAH domain and coiled-coil containing 1
BIVM-ERCC5 BIVM-ERCC5 readthrough
CAB39L calcium binding protein 39-like
CAMTA2 calmodulin binding transcription activator 2
CATSPERG catsper channel auxiliary subunit gamma
CEP164 centrosomal protein 164kDa
CEP250 centrosomal protein 250kDa
CTU2 cytosolic thiouridylase subunit 2 homolog (S. pombe)
DHRS2 dehydrogenase/reductase (SDR family) member 2
EGFR epidermal growth factor receptor
EIF3A eukaryotic translation initiation factor 3, subunit A
ERCC5 excision repair cross-complementation group 5
ERMP1 endoplasmic reticulum metallopeptidase 1
EZR ezrin
FNTA farnesyltransferase, CAAX box, alpha
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GLB1L2 galactosidase, beta 1-like 2
GPATCH2 G patch domain containing 2
H3F3C H3 histone, family 3C
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2
HEXIM2 hexamethylene bis-acetamide inducible 2
ICA1L islet cell autoantigen 1,69kDa-like
INTS2 integrator complex subunit 2
ITFG1 integrin alpha FG-GAP repeat containing 1
KCTD3 potassium channel tetramerization domain containing 3
KIAA1107 KIAA1107
KIF4B kinesin family member 4B
KMT2C lysine (K)-specific methyltransferase 2C
KRT13 keratin 13, type I
LARP1 La ribonucleoprotein domain family, member 1
LZTR1 leucine-zipper-like transcription regulator 1
MAN2A1 mannosidase, alpha, class 2A, member 1
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MAPK7 mitogen-activated protein kinase 7
MED4 mediator complex subunit 4
MON2 MON2 homolog (S. cerevisiae)
MYO7A myosin VIIA
MYRF myelin regulatory factor
NAA35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit
NARF nuclear prelamin A recognition factor
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NPHP4 nephronophthisis 4
NR1H2 nuclear receptor subfamily 1, group H, member 2
NUP210 nucleoporin 210kDa
PELO pelota homolog (Drosophila)
PEX10 peroxisomal biogenesis factor 10
PIEZO1 piezo-type mechanosensitive ion channel component 1
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PLEKHA5 pleckstrin homology domain containing, family A member 5
PRSS41 protease, serine, 41
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
PXN paxillin
RAB17 RAB17, member RAS oncogene family
RHOC ras homolog family member C
RND2 Rho family GTPase 2
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
SORBS1 sorbin and SH3 domain containing 1
SP4 Sp4 transcription factor
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive)
STAT5A signal transducer and activator of transcription 5A
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TBCC tubulin folding cofactor C
TBCK TBC1 domain containing kinase
TIAM1 T-cell lymphoma invasion and metastasis 1
TMEM120A transmembrane protein 120A
TMTC2 transmembrane and tetratricopeptide repeat containing 2
TP53 tumor protein p53
TPP2 tripeptidyl peptidase II
TXNRD3 thioredoxin reductase 3
UBA6 ubiquitin-like modifier activating enzyme 6
UBA7 ubiquitin-like modifier activating enzyme 7
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
USP22 ubiquitin specific peptidase 22
USP24 ubiquitin specific peptidase 24
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
VPS36 vacuolar protein sorting 36 homolog (S. cerevisiae)
WDR35 WD repeat domain 35
WWC3 WWC family member 3
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZFAND1 zinc finger, AN1-type domain 1
ZFHX4 zinc finger homeobox 4
ZIC1 Zic family member 1