NCI-H820 Gene Set

Dataset COSMIC Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description disease: papillary adenocarci- noma (lung primary) (Cell Line Ontology, CLO_0008119)
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302 genes mutated in the NCI-H820 cell line from the COSMIC Cell Line Gene Mutation Profiles dataset.

Symbol Name
AACS acetoacetyl-CoA synthetase
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8
ACTRT3 actin-related protein T3
ADAM20 ADAM metallopeptidase domain 20
ADAMTS19 ADAM metallopeptidase with thrombospondin type 1 motif, 19
ADGB androglobin
ADGRE2 adhesion G protein-coupled receptor E2
ADGRF5 adhesion G protein-coupled receptor F5
ADH6 alcohol dehydrogenase 6 (class V)
ADRB2 adrenoceptor beta 2, surface
AFF2 AF4/FMR2 family, member 2
AMPH amphiphysin
ANAPC5 anaphase promoting complex subunit 5
ANGEL2 angel homolog 2 (Drosophila)
ANKRD11 ankyrin repeat domain 11
ANKRD27 ankyrin repeat domain 27 (VPS9 domain)
AP4B1 adaptor-related protein complex 4, beta 1 subunit
AQP1 aquaporin 1 (Colton blood group)
ARFGEF3 ARFGEF family member 3
ARSK arylsulfatase family, member K
ATG3 autophagy related 3
BAHCC1 BAH domain and coiled-coil containing 1
BBX bobby sox homolog (Drosophila)
BLM Bloom syndrome, RecQ helicase-like
BNC2 basonuclin 2
BRDT bromodomain, testis-specific
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
C9 complement component 9
CAB39L calcium binding protein 39-like
CASP2 caspase 2, apoptosis-related cysteine peptidase
CC2D1B coiled-coil and C2 domain containing 1B
CCM2 cerebral cavernous malformation 2
CCND2 cyclin D2
CD244 CD244 molecule, natural killer cell receptor 2B4
CDH17 cadherin 17, LI cadherin (liver-intestine)
CDH5 cadherin 5, type 2 (vascular endothelium)
CDYL2 chromodomain protein, Y-like 2
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2
CEP250 centrosomal protein 250kDa
CES4A carboxylesterase 4A
CES5A carboxylesterase 5A
CETN1 centrin, EF-hand protein, 1
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CLCNKA chloride channel, voltage-sensitive Ka
CNOT3 CCR4-NOT transcription complex, subunit 3
CNOT4 CCR4-NOT transcription complex, subunit 4
CNTN2 contactin 2 (axonal)
COL11A1 collagen, type XI, alpha 1
COL6A2 collagen, type VI, alpha 2
CPXM2 carboxypeptidase X (M14 family), member 2
CRELD2 cysteine-rich with EGF-like domains 2
CSMD3 CUB and Sushi multiple domains 3
CTU2 cytosolic thiouridylase subunit 2 homolog (S. pombe)
CUX2 cut-like homeobox 2
DACH1 dachshund family transcription factor 1
DBF4B DBF4 zinc finger B
DCLK3 doublecortin-like kinase 3
DCLRE1A DNA cross-link repair 1A
DCSTAMP dendrocyte expressed seven transmembrane protein
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
DDX49 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
DEFB113 defensin, beta 113
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLAT dihydrolipoamide S-acetyltransferase
DNAH11 dynein, axonemal, heavy chain 11
DOCK5 dedicator of cytokinesis 5
DROSHA drosha, ribonuclease type III
E2F4 E2F transcription factor 4, p107/p130-binding
EDEM3 ER degradation enhancer, mannosidase alpha-like 3
EGFR epidermal growth factor receptor
EIF3A eukaryotic translation initiation factor 3, subunit A
EIF3B eukaryotic translation initiation factor 3, subunit B
ELAVL4 ELAV like neuron-specific RNA binding protein 4
ERCC5 excision repair cross-complementation group 5
ERCC6L excision repair cross-complementation group 6-like
ERMAP erythroblast membrane-associated protein (Scianna blood group)
EZR ezrin
F11 coagulation factor XI
FAHD2B fumarylacetoacetate hydrolase domain containing 2B
FAM118A family with sequence similarity 118, member A
FAM169A family with sequence similarity 169, member A
FAM19A5 family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
FAM65A family with sequence similarity 65, member A
FAT3 FAT atypical cadherin 3
FCGBP Fc fragment of IgG binding protein
FGG fibrinogen gamma chain
FIG4 FIG4 phosphoinositide 5-phosphatase
FNTA farnesyltransferase, CAAX box, alpha
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOXA3 forkhead box A3
FREM2 FRAS1 related extracellular matrix protein 2
FURIN furin (paired basic amino acid cleaving enzyme)
GABRR3 gamma-aminobutyric acid (GABA) A receptor, rho 3 (gene/pseudogene)
GFM2 G elongation factor, mitochondrial 2
GLB1L2 galactosidase, beta 1-like 2
GNAS GNAS complex locus
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPATCH2 G patch domain containing 2
GPHN gephyrin
GRAMD1C GRAM domain containing 1C
GRIK2 glutamate receptor, ionotropic, kainate 2
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2
HEXIM2 hexamethylene bis-acetamide inducible 2
HIST1H2BC histone cluster 1, H2bc
ICA1L islet cell autoantigen 1,69kDa-like
IGSF10 immunoglobulin superfamily, member 10
INHBC inhibin, beta C
INSRR insulin receptor-related receptor
INTS2 integrator complex subunit 2
IRX6 iroquois homeobox 6
ITFG1 integrin alpha FG-GAP repeat containing 1
ITGB4 integrin, beta 4
KAZN kazrin, periplakin interacting protein
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12
KCTD3 potassium channel tetramerization domain containing 3
KIAA1107 KIAA1107
KIAA1211 KIAA1211
KIAA1324 KIAA1324
KIF21B kinesin family member 21B
KLHDC8B kelch domain containing 8B
KLK12 kallikrein-related peptidase 12
KMT2C lysine (K)-specific methyltransferase 2C
KNG1 kininogen 1
KRT5 keratin 5, type II
KRT81 keratin 81, type II
LARP1 La ribonucleoprotein domain family, member 1
LCE1F late cornified envelope 1F
LGSN lengsin, lens protein with glutamine synthetase domain
LHB luteinizing hormone beta polypeptide
LPPR4 lipid phosphate phosphatase-related protein type 4
LRRIQ1 leucine-rich repeats and IQ motif containing 1
LRRN3 leucine rich repeat neuronal 3
LTC4S leukotriene C4 synthase
LZTR1 leucine-zipper-like transcription regulator 1
MAGEB10 melanoma antigen family B10
MAN2A1 mannosidase, alpha, class 2A, member 1
MAPK7 mitogen-activated protein kinase 7
MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2
MED4 mediator complex subunit 4
MON2 MON2 homolog (S. cerevisiae)
MPL MPL proto-oncogene, thrombopoietin receptor
MROH2A maestro heat-like repeat family member 2A
MROH7 maestro heat-like repeat family member 7
MSH4 mutS homolog 4
MSN moesin
MUC16 mucin 16, cell surface associated
MUM1L1 melanoma associated antigen (mutated) 1-like 1
MYH14 myosin, heavy chain 14, non-muscle
MYL5 myosin, light chain 5, regulatory
MYL7 myosin, light chain 7, regulatory
MYO10 myosin X
MYO1A myosin IA
MYO3A myosin IIIA
NAA35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit
NANOG Nanog homeobox
NCKAP5 NCK-associated protein 5
NEB nebulin
NEFM neurofilament, medium polypeptide
NEXN nexilin (F actin binding protein)
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NGDN neuroguidin, EIF4E binding protein
NHSL1 NHS-like 1
NLGN4Y neuroligin 4, Y-linked
NLRP4 NLR family, pyrin domain containing 4
NLRP5 NLR family, pyrin domain containing 5
NME5 NME/NM23 family member 5
NPHP4 nephronophthisis 4
NR1D2 nuclear receptor subfamily 1, group D, member 2
NR1H2 nuclear receptor subfamily 1, group H, member 2
NRP2 neuropilin 2
NUF2 NUF2, NDC80 kinetochore complex component
NUP210 nucleoporin 210kDa
NUP210L nucleoporin 210kDa-like
NXF1 nuclear RNA export factor 1
OR10H5 olfactory receptor, family 10, subfamily H, member 5
OR2A7 olfactory receptor, family 2, subfamily A, member 7
OR2W3 olfactory receptor, family 2, subfamily W, member 3
OR4C5 olfactory receptor, family 4, subfamily C, member 5 (gene/pseudogene)
OR4K5 olfactory receptor, family 4, subfamily K, member 5
PALD1 phosphatase domain containing, paladin 1
PCDHA11 protocadherin alpha 11
PCDHB18P protocadherin beta 18 pseudogene
PDZD2 PDZ domain containing 2
PELO pelota homolog (Drosophila)
PGBD1 piggyBac transposable element derived 1
PHF14 PHD finger protein 14
PIEZO1 piezo-type mechanosensitive ion channel component 1
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PIWIL3 piwi-like RNA-mediated gene silencing 3
PLEKHA5 pleckstrin homology domain containing, family A member 5
PLEKHG4 pleckstrin homology domain containing, family G (with RhoGef domain) member 4
PLEKHG4B pleckstrin homology domain containing, family G (with RhoGef domain) member 4B
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
PLSCR3 phospholipid scramblase 3
PMP2 peripheral myelin protein 2
PNLIPRP3 pancreatic lipase-related protein 3
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PPP1R3A protein phosphatase 1, regulatory subunit 3A
PRICKLE4 prickle homolog 4 (Drosophila)
PSEN2 presenilin 2
PSG2 pregnancy specific beta-1-glycoprotein 2
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
PTPDC1 protein tyrosine phosphatase domain containing 1
PXN paxillin
RAB17 RAB17, member RAS oncogene family
RASSF6 Ras association (RalGDS/AF-6) domain family member 6
RAX retina and anterior neural fold homeobox
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RECQL5 RecQ protein-like 5
RELN reelin
RET ret proto-oncogene
RHOC ras homolog family member C
RNH1 ribonuclease/angiogenin inhibitor 1
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RPUSD1 RNA pseudouridylate synthase domain containing 1
RUSC1 RUN and SH3 domain containing 1
RXFP4 relaxin/insulin-like family peptide receptor 4
RYR3 ryanodine receptor 3
SAGE1 sarcoma antigen 1
SAV1 salvador family WW domain containing protein 1
SCN3A sodium channel, voltage gated, type III alpha subunit
SELV selenoprotein V
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7
SETX senataxin
SHANK1 SH3 and multiple ankyrin repeat domains 1
SIGLEC7 sialic acid binding Ig-like lectin 7
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC24A4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
SLIT2 slit homolog 2 (Drosophila)
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa
SORBS1 sorbin and SH3 domain containing 1
SP4 Sp4 transcription factor
SPAG6 sperm associated antigen 6
SPECC1 sperm antigen with calponin homology and coiled-coil domains 1
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive)
SPRED3 sprouty-related, EVH1 domain containing 3
SRCAP Snf2-related CREBBP activator protein
SSC4D scavenger receptor cysteine rich family, 4 domains
STK10 serine/threonine kinase 10
TAAR8 trace amine associated receptor 8
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TAS1R1 taste receptor, type 1, member 1
TBCC tubulin folding cofactor C
TBCK TBC1 domain containing kinase
TGFBR3 transforming growth factor, beta receptor III
TIAM1 T-cell lymphoma invasion and metastasis 1
TIMMDC1 translocase of inner mitochondrial membrane domain containing 1
TJP1 tight junction protein 1
TM4SF1 transmembrane 4 L six family member 1
TMTC2 transmembrane and tetratricopeptide repeat containing 2
TNN tenascin N
TOP3A topoisomerase (DNA) III alpha
TP53 tumor protein p53
TPP2 tripeptidyl peptidase II
TRAF3IP2 TRAF3 interacting protein 2
TRAPPC9 trafficking protein particle complex 9
TRIM26 tripartite motif containing 26
TRNAU1AP tRNA selenocysteine 1 associated protein 1
TSSK1B testis-specific serine kinase 1B
TTLL4 tubulin tyrosine ligase-like family member 4
TUBA3E tubulin, alpha 3e
UBA6 ubiquitin-like modifier activating enzyme 6
UBA7 ubiquitin-like modifier activating enzyme 7
UIMC1 ubiquitin interaction motif containing 1
UNC13A unc-13 homolog A (C. elegans)
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
USH2A Usher syndrome 2A (autosomal recessive, mild)
USP22 ubiquitin specific peptidase 22
USP24 ubiquitin specific peptidase 24
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
VMP1 vacuole membrane protein 1
VPS36 vacuolar protein sorting 36 homolog (S. cerevisiae)
VWF von Willebrand factor
WDR27 WD repeat domain 27
WDR35 WD repeat domain 35
WDR60 WD repeat domain 60
WDR90 WD repeat domain 90
WNT7A wingless-type MMTV integration site family, member 7A
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZCCHC3 zinc finger, CCHC domain containing 3
ZFAND1 zinc finger, AN1-type domain 1
ZFHX4 zinc finger homeobox 4
ZFP64 ZFP64 zinc finger protein
ZFPM2 zinc finger protein, FOG family member 2
ZG16 zymogen granule protein 16
ZHX2 zinc fingers and homeoboxes 2
ZNF429 zinc finger protein 429
ZNF474 zinc finger protein 474
ZNF528 zinc finger protein 528
ZNF546 zinc finger protein 546
ZNF717 zinc finger protein 717
ZNF730 zinc finger protein 730
ZNF780B zinc finger protein 780B
ZNF799 zinc finger protein 799
ZNF836 zinc finger protein 836