NCI-H748 Gene Set

Dataset COSMIC Cell Line Gene CNV Profiles
Category genomics
Type cell line
Description disease: carcinoma; classic small cell lung cancer (lung primary) (Cell Line Ontology, CLO_0008115)
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Genes

358 genes with high or low copy number in NCI-H748 relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.

high copy number

Symbol Name Standardized Value
ARTN artemin 3.12177
DMAP1 DNA methyltransferase 1 associated protein 1 3.12177
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 3.12177
IPO13 importin 13 3.12177
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 3.12177
C1ORF210 chromosome 1 open reading frame 210 3.12177
KLF17 Kruppel-like factor 17 3.12177
DPH2 DPH2 homolog (S. cerevisiae) 3.12177
ERI3 ERI1 exoribonuclease family member 3 3.12177
CCDC24 coiled-coil domain containing 24 3.12177
KC6 keratoconus gene 6 3.12177
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b 3.12177
TMEM125 transmembrane protein 125 3.12177
EBNA1BP2 EBNA1 binding protein 2 2.93899
FOXJ3 forkhead box J3 2.93899
HYI hydroxypyruvate isomerase (putative) 2.93899
MPL MPL proto-oncogene, thrombopoietin receptor 2.93899
PTPRF protein tyrosine phosphatase, receptor type, F 2.93899
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 2.93899
KDM4A-AS1 KDM4A antisense RNA 1 2.93899
MED8 mediator complex subunit 8 2.93899
MTUS2 microtubule associated tumor suppressor candidate 2 2.93899
KDM4A lysine (K)-specific demethylase 4A 2.93899
PPIH peptidylprolyl isomerase H (cyclophilin H) 2.93899
FAM183A family with sequence similarity 183, member A 2.93899
CDC20 cell division cycle 20 2.93899
MTUS2-AS1 MTUS2 antisense RNA 1 2.93899
PPCS phosphopantothenoylcysteine synthetase 2.93899
SZT2 seizure threshold 2 homolog (mouse) 2.93899
ZMYND12 zinc finger, MYND-type containing 12 2.93899
GUCA2A guanylate cyclase activator 2A (guanylin) 2.93899
GUCA2B guanylate cyclase activator 2B (uroguanylin) 2.93899
SLC46A3 solute carrier family 46, member 3 2.93899
CCDC30 coiled-coil domain containing 30 2.93899
UBL3 ubiquitin-like 3 2.93899
ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 2.93899
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 2.93899
YBX1 Y box binding protein 1 2.93899
RIMKLA ribosomal modification protein rimK-like family member A 2.93899
ELOVL1 ELOVL fatty acid elongase 1 2.93899
SLC2A1-AS1 SLC2A1 antisense RNA 1 2.93899
LNX2 ligand of numb-protein X 2 2.76305
RPL21 ribosomal protein L21 2.76305
TEX26-AS1 TEX26 antisense RNA 1 2.76305
FLT3 fms-related tyrosine kinase 3 2.76305
HSPH1 heat shock 105kDa/110kDa protein 1 2.76305
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 2.76305
PARP4 poly (ADP-ribose) polymerase family, member 4 2.76305
ERMAP erythroblast membrane-associated protein (Scianna blood group) 2.76305
ZAR1L zygote arrest 1-like 2.76305
MTIF3 mitochondrial translational initiation factor 3 2.76305
B3GALTL beta 1,3-galactosyltransferase-like 2.76305
MIR2276 microRNA 2276 2.76305
RNF17 ring finger protein 17 2.76305
GTF3A general transcription factor IIIA 2.76305
SPATA13 spermatogenesis associated 13 2.76305
GSX1 GS homeobox 1 2.76305
RXFP2 relaxin/insulin-like family peptide receptor 2 2.76305
ALOX5AP arachidonate 5-lipoxygenase-activating protein 2.76305
C1ORF50 chromosome 1 open reading frame 50 2.76305
P3H1 prolyl 3-hydroxylase 1 2.76305
SPATA13-AS1 SPATA13 antisense RNA 1 2.76305
AMER2 APC membrane recruitment protein 2 2.76305
SNORD102 small nucleolar RNA, C/D box 102 2.76305
GPR12 G protein-coupled receptor 12 2.76305
KATNAL1 katanin p60 subunit A-like 1 2.76305
LINC00426 long intergenic non-protein coding RNA 426 2.76305
POMP proteasome maturation protein 2.76305
SHISA2 shisa family member 2 2.76305
LOC100129924 uncharacterized LOC100129924 2.76305
ZNF691 zinc finger protein 691 2.76305
POLR1D polymerase (RNA) I polypeptide D, 16kDa 2.76305
CLDN19 claudin 19 2.76305
USP12 ubiquitin specific peptidase 12 2.76305
TEX26 testis expressed 26 2.76305
NUPL1 nucleoporin like 1 2.76305
RASL11A RAS-like, family 11, member A 2.76305
LINC00544 long intergenic non-protein coding RNA 544 2.76305
PABPC3 poly(A) binding protein, cytoplasmic 3 2.76305
RNF6 ring finger protein (C3H2C3 type) 6 2.76305
CDK8 cyclin-dependent kinase 8 2.76305
TPTE2P6 transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 pseudogene 6 2.76305
C1QTNF9 C1q and tumor necrosis factor related protein 9 2.76305
LINC00297 long intergenic non-protein coding RNA 297 2.76305
MEDAG mesenteric estrogen-dependent adipogenesis 2.76305
HMGB1 high mobility group box 1 2.76305
FRY furry homolog (Drosophila) 2.76305
CCDC23 coiled-coil domain containing 23 2.76305
PAN3-AS1 PAN3 antisense RNA 1 2.76305
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 2.76305
TPTE2P1 transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 pseudogene 1 2.76305
MTMR6 myotubularin related protein 6 2.76305
LINC00398 long intergenic non-protein coding RNA 398 2.76305
CENPJ centromere protein J 2.76305
N4BP2L2-IT2 N4BPL2 intronic transcript 2 2.64759
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 2.64759
BRCA2 breast cancer 2, early onset 2.64759
ATP5EP2 ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit pseudogene 2 2.64759
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1 2.64759
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2 2.64759
N4BP2L1 NEDD4 binding protein 2-like 1 2.64759
N4BP2L2 NEDD4 binding protein 2-like 2 2.64759
EDN2 endothelin 2 2.64759
PDX1 pancreatic and duodenal homeobox 1 2.64759
SNORA27 small nucleolar RNA, H/ACA box 27 2.64759
CDX2 caudal type homeobox 2 2.64759
LINC00423 long intergenic non-protein coding RNA 423 2.59653
STARD13-AS STARD13 antisense RNA 2.59653
PDS5B PDS5 cohesin associated factor B 2.59653
KL klotho 2.59653
STARD13 StAR-related lipid transfer (START) domain containing 13 2.59653
MIR30E microRNA 30e 2.44392
MIR30C1 microRNA 30c-1 2.44392
KIAA0754 KIAA0754 2.39327
NFYC nuclear transcription factor Y, gamma 2.39327
SLFNL1-AS1 SLFNL1 antisense RNA 1 2.39327
RIMS3 regulating synaptic membrane exocytosis 3 2.39327
CTPS1 CTP synthase 1 2.39327
SLFNL1 schlafen-like 1 2.39327
SCMH1 sex comb on midleg homolog 1 (Drosophila) 2.39327
KCNQ4 potassium channel, voltage gated KQT-like subfamily Q, member 4 2.39327
CITED4 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4 2.39327
EXO5 exonuclease 5 2.35236
SNORA55 small nucleolar RNA, H/ACA box 55 2.35236
ZFP69 ZFP69 zinc finger protein 2.35236
PPIEL peptidylprolyl isomerase E-like pseudogene 2.35236
ZFP69B ZFP69 zinc finger protein B 2.35236
ZNF684 zinc finger protein 684 2.35236
MACF1 microtubule-actin crosslinking factor 1 2.35236
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) 2.35236
COL9A2 collagen, type IX, alpha 2 2.3178
SMAP2 small ArfGAP2 2.3178
HEYL hes-related family bHLH transcription factor with YRPW motif-like 2.3178
ZMPSTE24 zinc metallopeptidase STE24 2.30944
NT5C1A 5'-nucleotidase, cytosolic IA 2.30944
BMP8A bone morphogenetic protein 8a 2.30944
PPT1 palmitoyl-protein thioesterase 1 2.30944
TMCO2 transmembrane and coiled-coil domains 2 2.30944
RLF rearranged L-myc fusion 2.283
HPCAL4 hippocalcin like 4 2.283
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 2.283
MFSD2A major facilitator superfamily domain containing 2A 2.25904
OXCT2 3-oxoacid CoA transferase 2 2.24845
PPIE peptidylprolyl isomerase E (cyclophilin E) 2.24845
BMP8B bone morphogenetic protein 8b 2.24845
TRIT1 tRNA isopentenyltransferase 1 2.24139
LRRC14B leucine rich repeat containing 14B 2.22123
NSUN2 NOP2/Sun RNA methyltransferase family, member 2 2.22123
PLEKHG4B pleckstrin homology domain containing, family G (with RhoGef domain) member 4B 2.22123
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) 2.22123
EXOC3-AS1 EXOC3 antisense RNA 1 2.21727
NKD2 naked cuticle homolog 2 (Drosophila) 2.21727
UBE2QL1 ubiquitin-conjugating enzyme E2Q family-like 1 2.21727
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7 2.21727
C5ORF38 chromosome 5 open reading frame 38 2.21727
CCDC127 coiled-coil domain containing 127 2.21727
IRX2 iroquois homeobox 2 2.21727
PDCD6 programmed cell death 6 2.21727
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 2.21727
CLPTM1L CLPTM1-like 2.21727
IRX4 iroquois homeobox 4 2.21727
MIR4635 microRNA 4635 2.21727
MIR4457 microRNA 4457 2.21727
LOC100506688 uncharacterized LOC100506688 2.21727
AHRR aryl-hydrocarbon receptor repressor 2.21727
TPPP tubulin polymerization promoting protein 2.21258
PP7080 uncharacterized LOC25845 2.21258
MIR4454 microRNA 4454 2.21258
SLC6A19 solute carrier family 6 (neutral amino acid transporter), member 19 2.21258
FLJ33360 FLJ33360 protein 2.21258
EXOC3 exocyst complex component 3 2.21258
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 2.21258
MED10 mediator complex subunit 10 2.21258
CEP72 centrosomal protein 72kDa 2.21258
MIR4456 microRNA 4456 2.21258
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) 2.21258
MIR4277 microRNA 4277 2.21258
TRIP13 thyroid hormone receptor interactor 13 2.21258
MRPL36 mitochondrial ribosomal protein L36 2.21258
LOC100996325 uncharacterized LOC100996325 2.21258
LPCAT1 lysophosphatidylcholine acyltransferase 1 2.21096
SLC6A18 solute carrier family 6 (neutral amino acid transporter), member 18 2.21096
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 2.21096
IRX1 iroquois homeobox 1 2.21096
ADAMTS16 ADAM metallopeptidase with thrombospondin type 1 motif, 16 2.21096
C5ORF49 chromosome 5 open reading frame 49 2.21096
LOC728613 programmed cell death 6 pseudogene 2.21096
TERT telomerase reverse transcriptase 2.21096
SDHAP3 succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 3 2.21096
FASTKD3 FAST kinase domains 3 2.20309
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase 2.20309
FAM173B family with sequence similarity 173, member B 2.20309
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 2.20309
CMBL carboxymethylenebutenolidase homolog (Pseudomonas) 2.20309
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) 2.20309
ROPN1L rhophilin associated tail protein 1-like 2.20309
ROPN1L-AS1 ROPN1L antisense RNA 1 2.20309
DAP death-associated protein 2.20309
ANKRD33B ankyrin repeat domain 33B 2.20309
ZDHHC11 zinc finger, DHHC-type containing 11 2.20309
LOC285696 uncharacterized LOC285696 2.20053
C5ORF22 chromosome 5 open reading frame 22 2.20053
MIR4458 microRNA 4458 2.20053
LOC729506 uncharacterized LOC729506 2.20053
DROSHA drosha, ribonuclease type III 2.20053
MIR4636 microRNA 4636 2.20053
TARS threonyl-tRNA synthetase 2.20053
SNORD123 small nucleolar RNA, C/D box 123 2.19863
SUB1 SUB1 homolog (S. cerevisiae) 2.19863
MARCH11 membrane-associated ring finger (C3HC4) 11 2.19863
FAM134B family with sequence similarity 134, member B 2.19863
RXFP3 relaxin/insulin-like family peptide receptor 3 2.19863
CARD6 caspase recruitment domain family, member 6 2.19863
TTC33 tetratricopeptide repeat domain 33 2.19863
RPL37 ribosomal protein L37 2.19863
BASP1 brain abundant, membrane attached signal protein 1 2.19863
LOC340113 uncharacterized LOC340113 2.19863
LOC100506548 uncharacterized LOC100506548 2.19863
SNORD72 small nucleolar RNA, C/D box 72 2.19863
ZNF622 zinc finger protein 622 2.19863
NPR3 natriuretic peptide receptor 3 2.19863
TAS2R1 taste receptor, type 2, member 1 2.19863
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 2.19863
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit 2.19863
PLCXD3 phosphatidylinositol-specific phospholipase C, X domain containing 3 2.19301
MROH2B maestro heat-like repeat family member 2B 2.19301
C1QTNF3 C1q and tumor necrosis factor related protein 3 2.19301
SLC45A2 solute carrier family 45, member 2 2.19301
MYO10 myosin X 2.19301
AMACR alpha-methylacyl-CoA racemase 2.19301
PTGER4 prostaglandin E receptor 4 (subtype EP4) 2.19301
LOC401177 uncharacterized LOC401177 2.19301
C7 complement component 7 2.19301
C9 complement component 9 2.18778
GDNF-AS1 GDNF antisense RNA 1 (head to head) 2.18778
FYB FYN binding protein 2.18778
MIR4637 microRNA 4637 2.18778
EGFLAM-AS4 EGFLAM antisense RNA 4 2.18778
EGFLAM EGF-like, fibronectin type III and laminin G domains 2.18778
EGFLAM-AS2 EGFLAM antisense RNA 2 2.18778
GDNF glial cell derived neurotrophic factor 2.18778
C5ORF42 chromosome 5 open reading frame 42 2.18778
LIFR leukemia inhibitory factor receptor alpha 2.18778
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 2.18778
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 2.18778
DNAH5 dynein, axonemal, heavy chain 5 2.18778
SPEF2 sperm flagellar 2 2.18778
RICTOR RPTOR independent companion of MTOR, complex 2 2.18778
FAM105A family with sequence similarity 105, member A 2.18778
C6 complement component 6 2.18778
WDR70 WD repeat domain 70 2.18778
ANKH ANKH inorganic pyrophosphate transport regulator 2.18778
NUP155 nucleoporin 155kDa 2.18778
LOC100130744 uncharacterized LOC100130744 2.18778
MIR3650 microRNA 3650 2.18778
IL7R interleukin 7 receptor 2.18778
ANXA2R annexin A2 receptor 2.18124
LOC100132356 uncharacterized LOC100132356 2.18124
TRIO trio Rho guanine nucleotide exchange factor 2.18124
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 2.18124
LOC153684 uncharacterized LOC153684 2.18124
CAPSL calcyphosine-like 2.18124
LOC100506639 uncharacterized LOC100506639 2.18124
NIPBL Nipped-B homolog (Drosophila) 2.18124
C5ORF51 chromosome 5 open reading frame 51 2.18124
OSMR oncostatin M receptor 2.18124
FBXO4 F-box protein 4 2.18124
ZNF131 zinc finger protein 131 2.18124
OXCT1 3-oxoacid CoA transferase 1 2.18124
LOC646719 2.18124
CCL28 chemokine (C-C motif) ligand 28 2.18124
GHR growth hormone receptor 2.18124
LOC648987 uncharacterized LOC648987 2.18124
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 2.17694
FBXL7 F-box and leucine-rich repeat protein 7 2.17694
CCDC152 coiled-coil domain containing 152 2.17694
RANBP3L RAN binding protein 3-like 2.17694
UGT3A2 UDP glycosyltransferase 3 family, polypeptide A2 2.17694
LMBRD2 LMBR1 domain containing 2 2.17694
UGT3A1 UDP glycosyltransferase 3 family, polypeptide A1 2.17694
MIR580 microRNA 580 2.17694
SEPP1 selenoprotein P, plasma, 1 2.17694
MRPS30 mitochondrial ribosomal protein S30 2.17694
C5ORF28 chromosome 5 open reading frame 28 2.17694
PAIP1 poly(A) binding protein interacting protein 1 2.17694
C5ORF34 chromosome 5 open reading frame 34 2.17694
RAI14 retinoic acid induced 14 2.16947
DNAJC21 DnaJ (Hsp40) homolog, subfamily C, member 21 2.16947
AGXT2 alanine--glyoxylate aminotransferase 2 2.16947
TTC23L tetratricopeptide repeat domain 23-like 2.16947
FGF10 fibroblast growth factor 10 2.16947
PRLR prolactin receptor 2.16947
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 2.16947
RAD1 RAD1 checkpoint DNA exonuclease 2.16947
BRIX1 BRX1, biogenesis of ribosomes 2.16947
NNT nicotinamide nucleotide transhydrogenase 2.16816
LOC340107 uncharacterized LOC340107 2.16307
GALNT13 polypeptide N-acetylgalactosaminyltransferase 13 2.14311
EEF1DP3 eukaryotic translation elongation factor 1 delta pseudogene 3 2.14135
LOC100144595 uncharacterized LOC100144595 2.14116
LATS2 large tumor suppressor kinase 2 2.1339
IFT88 intraflagellar transport 88 2.1316
FGF9 fibroblast growth factor 9 2.12931
IL17D interleukin 17D 2.12931
LINC00424 long intergenic non-protein coding RNA 424 2.12931
XPO4 exportin 4 2.12931
N6AMT2 N-6 adenine-specific DNA methyltransferase 2 (putative) 2.12931
TNFRSF19 tumor necrosis factor receptor superfamily, member 19 2.12703
SAP18 Sin3A-associated protein, 18kDa 2.12703
SACS-AS1 SACS antisense RNA 1 2.12703
LINC00327 long intergenic non-protein coding RNA 327 2.12703
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) 2.12703
SACS sacsin molecular chaperone 2.12703
SKA3 spindle and kinetochore associated complex subunit 3 2.12703
ZDHHC20 zinc finger, DHHC-type containing 20 2.12703
MICU2 mitochondrial calcium uptake 2 2.12703
MIPEPP3 mitochondrial intermediate peptidase pseudogene 3 2.12703
BASP1P1 brain abundant, membrane attached signal protein 1 pseudogene 1 2.12703
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3 2.12703
C1QTNF9B C1q and tumor necrosis factor related protein 9B 2.12225
FLT1 fms-related tyrosine kinase 1 2.12225
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1 2.12225
PAN3 PAN3 poly(A) specific ribonuclease subunit 2.12225
WASF3 WAS protein family, member 3 2.12225
ANKRD20A19P ankyrin repeat domain 20 family, member A19, pseudogene 2.12225
USPL1 ubiquitin specific peptidase like 1 2.12225
MIPEP mitochondrial intermediate peptidase 2.12225
PAPD7 PAP associated domain containing 7 2.05661
MIR4278 microRNA 4278 2.05661
LOC442132 golgin A6 family-like 1 pseudogene 2.05559
BRD9 bromodomain containing 9 2.05559
ADCY2 adenylate cyclase 2 (brain) 2.05422
ZFR zinc finger RNA binding protein 2.05311
MIR4279 microRNA 4279 2.05311
MTMR12 myotubularin related protein 12 2.05311
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12 2.05242
LOC285692 uncharacterized LOC285692 2.0522
PDZD2 PDZ domain containing 2 2.0521
GOLPH3 golgi phosphoprotein 3 (coat-protein) 2.0521
CTNND2 catenin (cadherin-associated protein), delta 2 2.05129
LSP1P3 lymphocyte-specific protein 1 pseudogene 3 2.05072
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) 2.05045
PRDM9 PR domain containing 9 2.05041
CDH10 cadherin 10, type 2 (T2-cadherin) 2.05014
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene 2.04969
CDH9 cadherin 9, type 2 (T1-cadherin) 2.04969
GUSBP1 glucuronidase, beta pseudogene 1 2.0489
CDH12 cadherin 12, type 2 (N-cadherin 2) 2.0489
CDH18 cadherin 18, type 2 2.0489
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker) 2.04842
IGHE immunoglobulin heavy constant epsilon 2.04816
IGHD immunoglobulin heavy constant delta 2.04803
ADAM6 ADAM metallopeptidase domain 6 (pseudogene) 2.04767
KIAA0125 KIAA0125 2.04731
LINC00226 long intergenic non-protein coding RNA 226 2.04712

low copy number

Symbol Name Standardized Value
PSG4 pregnancy specific beta-1-glycoprotein 4 -2.75301
LOC284344 uncharacterized LOC284344 -2.74526
ALG1L2 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase-like 2 -2.73329