NCI-H747 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
Description disease: colorectal adenocarcinoma (Cell Line Ontology, CLO_0008114)
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Genes

295 genes with high or low expression in NCI-H747 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
RPA3 replication protein A3, 14kDa 2.68714
FOXJ2 forkhead box J2 2.42281
PPARD peroxisome proliferator-activated receptor delta 2.40282
SPTAN1 spectrin, alpha, non-erythrocytic 1 2.38605
KLK7 kallikrein-related peptidase 7 2.23717
RGS7 regulator of G-protein signaling 7 2.23549
KRT34 keratin 34, type I 2.21574
MELK maternal embryonic leucine zipper kinase 2.119
ADAP1 ArfGAP with dual PH domains 1 2.1088
HOXA5 homeobox A5 2.04632
TUBB4B tubulin, beta 4B class IVb 2.03147
BZW2 basic leucine zipper and W2 domains 2 2.02923
LASP1 LIM and SH3 protein 1 2.01901
CST6 cystatin E/M 2.00773
LMNB2 lamin B2 2.00426
AGFG2 ArfGAP with FG repeats 2 2.00161
MTMR1 myotubularin related protein 1 1.98545
HOXA10 homeobox A10 1.98041
HN1 hematological and neurological expressed 1 1.96319
BAIAP2 BAI1-associated protein 2 1.94102
GIPC1 GIPC PDZ domain containing family, member 1 1.92376
ZNF185 zinc finger protein 185 (LIM domain) 1.90948
ZBED2 zinc finger, BED-type containing 2 1.90697
DLG1 discs, large homolog 1 (Drosophila) 1.89929
PTGES2 prostaglandin E synthase 2 1.86526
BCL2L1 BCL2-like 1 1.85829
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 1.85208
AP3S1 adaptor-related protein complex 3, sigma 1 subunit 1.84775
HOXA6 homeobox A6 1.84432
LMNA lamin A/C 1.83853
FAM120A family with sequence similarity 120A 1.83836
MRPL23 mitochondrial ribosomal protein L23 1.83203
EIF3B eukaryotic translation initiation factor 3, subunit B 1.81851
SCRN1 secernin 1 1.77892
KRT33A keratin 33A, type I 1.77844
DTX2 deltex 2, E3 ubiquitin ligase 1.77317
SFT2D2 SFT2 domain containing 2 1.77172
BTG4 B-cell translocation gene 4 1.76798
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 1.76548
NRG1 neuregulin 1 1.76337
CAPN6 calpain 6 1.76207
CAPN1 calpain 1, (mu/I) large subunit 1.75579
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 1.75145
DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 1.745
NSDHL NAD(P) dependent steroid dehydrogenase-like 1.73971
DIAPH1 diaphanous-related formin 1 1.73898
KRT20 keratin 20, type I 1.73504
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 1.72516
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal) 1.72257
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22 1.71847
HOXA9 homeobox A9 1.71776
CDC14B cell division cycle 14B 1.71487
ZNF551 zinc finger protein 551 1.70821
UMPS uridine monophosphate synthetase 1.7066
TK1 thymidine kinase 1, soluble 1.70032
CUEDC1 CUE domain containing 1 1.70011
CACNG4 calcium channel, voltage-dependent, gamma subunit 4 1.69336
CHMP1A charged multivesicular body protein 1A 1.69186
PTPN1 protein tyrosine phosphatase, non-receptor type 1 1.68953
HMMR hyaluronan-mediated motility receptor (RHAMM) 1.68332
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) 1.67901
ERBB2IP erbb2 interacting protein 1.67341
SIRT7 sirtuin 7 1.67159
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 1.66794
CLDN9 claudin 9 1.6666
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 1.66449
PRG4 proteoglycan 4 1.65668
HDGF hepatoma-derived growth factor 1.65505
MAP6D1 MAP6 domain containing 1 1.65187
RAB5C RAB5C, member RAS oncogene family 1.64277
DIAPH2-AS1 DIAPH2 antisense RNA 1 1.63259
KCNK13 potassium channel, two pore domain subfamily K, member 13 1.61653
POLA2 polymerase (DNA directed), alpha 2, accessory subunit 1.60988
PDE11A phosphodiesterase 11A 1.6033
PCDH1 protocadherin 1 1.60268
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 1.60055
WWC1 WW and C2 domain containing 1 1.59753
HOXB8 homeobox B8 1.59448
CLTA clathrin, light chain A 1.59237
CCNB1 cyclin B1 1.58299
TMEM106B transmembrane protein 106B 1.57898
ADRM1 adhesion regulating molecule 1 1.57566
CLTB clathrin, light chain B 1.57156
KIAA1654 KIAA1654 protein 1.57047
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa 1.56957
TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa 1.56912
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 1.56544
CAST calpastatin 1.56007
EPS15P1 epidermal growth factor receptor pathway substrate 15 pseudogene 1 1.55993
TAF4 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa 1.55509
VGLL1 vestigial-like family member 1 1.54838
HOXA2 homeobox A2 1.54425
TCHH trichohyalin 1.53774
NAP1L4 nucleosome assembly protein 1-like 4 1.53557
STIP1 stress-induced phosphoprotein 1 1.53411
DUSP14 dual specificity phosphatase 14 1.53364
PPP6C protein phosphatase 6, catalytic subunit 1.5213
RNF141 ring finger protein 141 1.51636
DIDO1 death inducer-obliterator 1 1.51098
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1 1.50949
S100A11 S100 calcium binding protein A11 1.50753
PTTG3P pituitary tumor-transforming 3, pseudogene 1.50641
GPR32 G protein-coupled receptor 32 1.49987
DIRAS3 DIRAS family, GTP-binding RAS-like 3 1.49574
SOSTDC1 sclerostin domain containing 1 1.48933
ATG12 autophagy related 12 1.4886
HOXA7 homeobox A7 1.48856
TCOF1 Treacher Collins-Franceschetti syndrome 1 1.4858
UBE2A ubiquitin-conjugating enzyme E2A 1.48516
CSTF2 cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa 1.48124
TPRA1 transmembrane protein, adipocyte asscociated 1 1.47708
HSPG2 heparan sulfate proteoglycan 2 1.47671
EPB41L1 erythrocyte membrane protein band 4.1-like 1 1.47378
HOXB3 homeobox B3 1.47355
MUC4 mucin 4, cell surface associated 1.45604
ZNF207 zinc finger protein 207 1.45473
STYK1 serine/threonine/tyrosine kinase 1 1.44752
COL13A1 collagen, type XIII, alpha 1 1.44742
KRT23 keratin 23, type I 1.44558
SHCBP1 SHC SH2-domain binding protein 1 1.44282
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 1.4416
LMX1B LIM homeobox transcription factor 1, beta 1.43992
KIF25 kinesin family member 25 1.43978
OSR2 odd-skipped related transciption factor 2 1.43692
PRR13 proline rich 13 1.43518
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) 1.43436
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) 1.43369
HOXB6 homeobox B6 1.43299
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1 1.43096
KIF4A kinesin family member 4A 1.42544
SSNA1 Sjogren syndrome nuclear autoantigen 1 1.42482
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 1.422
SSFA2 sperm specific antigen 2 1.42138
COTL1 coactosin-like F-actin binding protein 1 1.4182

low expression

Symbol Name Standardized Value
FECH ferrochelatase -3.53716
UST uronyl-2-sulfotransferase -3.5242
COPS2 COP9 signalosome subunit 2 -3.27083
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4 -3.2218
OXA1L oxidase (cytochrome c) assembly 1-like -2.87511
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) -2.64197
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2 -2.62071
GTDC1 glycosyltransferase-like domain containing 1 -2.61223
SMAD2 SMAD family member 2 -2.52918
MOAP1 modulator of apoptosis 1 -2.47383
MAN2A2 mannosidase, alpha, class 2A, member 2 -2.44019
CRBN cereblon -2.36138
AFG3L2 AFG3-like AAA ATPase 2 -2.3527
ADORA2A adenosine A2a receptor -2.33947
TEX15 testis expressed 15 -2.33303
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain -2.29616
CIDEC cell death-inducing DFFA-like effector c -2.29451
SAP18 Sin3A-associated protein, 18kDa -2.26153
PRMT2 protein arginine methyltransferase 2 -2.25898
RNF41 ring finger protein 41, E3 ubiquitin protein ligase -2.19594
CHMP1B charged multivesicular body protein 1B -2.17359
HNF1A HNF1 homeobox A -2.17128
MAPK11 mitogen-activated protein kinase 11 -2.13847
MEF2A myocyte enhancer factor 2A -2.09147
MBIP MAP3K12 binding inhibitory protein 1 -2.07454
GOLGA8B golgin A8 family, member B -2.06608
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 -2.06192
SCGN secretagogin, EF-hand calcium binding protein -2.06045
WDR7 WD repeat domain 7 -2.0198
KLHDC2 kelch domain containing 2 -2.018
TSPAN9 tetraspanin 9 -2.0019
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 -1.99848
RPF1 ribosome production factor 1 homolog (S. cerevisiae) -1.99742
ERG v-ets avian erythroblastosis virus E26 oncogene homolog -1.98121
TM2D3 TM2 domain containing 3 -1.97806
MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle -1.94974
ALKBH1 alkB, alkylation repair homolog 1 (E. coli) -1.94439
ANKRD46 ankyrin repeat domain 46 -1.94057
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5 -1.93578
RNMT RNA (guanine-7-) methyltransferase -1.9312
ZNF24 zinc finger protein 24 -1.92971
DPP8 dipeptidyl-peptidase 8 -1.92357
FOXN3 forkhead box N3 -1.92215
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle -1.91428
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene -1.90943
BTBD1 BTB (POZ) domain containing 1 -1.88332
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic -1.8806
THOC1 THO complex 1 -1.87828
IKZF2 IKAROS family zinc finger 2 (Helios) -1.86406
GLT8D1 glycosyltransferase 8 domain containing 1 -1.85989
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) -1.85904
FERMT2 fermitin family member 2 -1.84362
TCEA2 transcription elongation factor A (SII), 2 -1.83904
CECR7 cat eye syndrome chromosome region, candidate 7 (non-protein coding) -1.83636
NPPA natriuretic peptide A -1.82993
GOLGA8A golgin A8 family, member A -1.8202
TRAPPC8 trafficking protein particle complex 8 -1.81843
WASF3 WAS protein family, member 3 -1.81189
ZFP37 ZFP37 zinc finger protein -1.80934
PTPRG protein tyrosine phosphatase, receptor type, G -1.80257
SIRT4 sirtuin 4 -1.79239
TMED5 transmembrane emp24 protein transport domain containing 5 -1.78731
ACF Asymmetric crying facies (Cayler cardiofacial syndrome) -1.78606
KIF5A kinesin family member 5A -1.78394
SYNC syncoilin, intermediate filament protein -1.78099
SLC26A2 solute carrier family 26 (anion exchanger), member 2 -1.77757
HPCAL4 hippocalcin like 4 -1.76564
NEFL neurofilament, light polypeptide -1.75755
SLC39A6 solute carrier family 39 (zinc transporter), member 6 -1.75735
MMP14 matrix metallopeptidase 14 (membrane-inserted) -1.75598
OAZ2 ornithine decarboxylase antizyme 2 -1.75579
CNIH3 cornichon family AMPA receptor auxiliary protein 3 -1.75092
TRIT1 tRNA isopentenyltransferase 1 -1.7466
ZNF516 zinc finger protein 516 -1.74615
NIPSNAP3B nipsnap homolog 3B (C. elegans) -1.7376
SLC39A9 solute carrier family 39, member 9 -1.73691
SLC25A30 solute carrier family 25, member 30 -1.7352
CUL7 cullin 7 -1.73324
PGAP1 post-GPI attachment to proteins 1 -1.7314
ZNF225 zinc finger protein 225 -1.71829
PSMG2 proteasome (prosome, macropain) assembly chaperone 2 -1.71114
ETFDH electron-transferring-flavoprotein dehydrogenase -1.70673
SRR serine racemase -1.70639
RGN regucalcin -1.70118
IFNW1 interferon, omega 1 -1.7001
RSPH14 radial spoke head 14 homolog (Chlamydomonas) -1.6991
COL1A1 collagen, type I, alpha 1 -1.69703
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) -1.68083
CARTPT CART prepropeptide -1.68068
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) -1.67586
SHPRH SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase -1.6696
PTPRO protein tyrosine phosphatase, receptor type, O -1.65657
FBN1 fibrillin 1 -1.64981
ZCCHC11 zinc finger, CCHC domain containing 11 -1.63146
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa -1.62665
ZNF512B zinc finger protein 512B -1.62221
EIF1B eukaryotic translation initiation factor 1B -1.61779
KIAA0513 KIAA0513 -1.61716
KDM4A lysine (K)-specific demethylase 4A -1.61276
ACTR10 actin-related protein 10 homolog (S. cerevisiae) -1.60894
CARD8 caspase recruitment domain family, member 8 -1.60763
DCAF13 DDB1 and CUL4 associated factor 13 -1.60609
SNX16 sorting nexin 16 -1.60246
CBS cystathionine-beta-synthase -1.59756
MAGEH1 melanoma antigen family H1 -1.58776
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal) -1.58658
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow -1.58418
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa -1.5836
DLX2 distal-less homeobox 2 -1.58113
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1 -1.5792
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1 -1.57214
TMEM168 transmembrane protein 168 -1.56078
BICC1 BicC family RNA binding protein 1 -1.55735
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) -1.55172
MRPL57 mitochondrial ribosomal protein L57 -1.54954
LRRN3 leucine rich repeat neuronal 3 -1.54493
UBL3 ubiquitin-like 3 -1.54482
CCDC28B coiled-coil domain containing 28B -1.54313
HLTF helicase-like transcription factor -1.54042
MC4R melanocortin 4 receptor -1.53979
ARPP19 cAMP-regulated phosphoprotein, 19kDa -1.53907
PDGFC platelet derived growth factor C -1.5303
CHST10 carbohydrate sulfotransferase 10 -1.52123
GLRB glycine receptor, beta -1.52044
TTC3 tetratricopeptide repeat domain 3 -1.51881
PCGF3 polycomb group ring finger 3 -1.51715
HSPA13 heat shock protein 70kDa family, member 13 -1.51044
PRR3 proline rich 3 -1.50973
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 -1.50692
BMP10 bone morphogenetic protein 10 -1.50218
TLR1 toll-like receptor 1 -1.50199
MTX2 metaxin 2 -1.49809
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O -1.47926
TUBGCP5 tubulin, gamma complex associated protein 5 -1.47576
SMO smoothened, frizzled class receptor -1.47506
WDR47 WD repeat domain 47 -1.47501
BBS4 Bardet-Biedl syndrome 4 -1.47207
FEM1B fem-1 homolog b (C. elegans) -1.46644
CHSY1 chondroitin sulfate synthase 1 -1.46392
SPAG7 sperm associated antigen 7 -1.45851
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -1.45713
SPATA5L1 spermatogenesis associated 5-like 1 -1.45574
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa -1.45458
MAP3K12 mitogen-activated protein kinase kinase kinase 12 -1.45069
RPL17 ribosomal protein L17 -1.44959
TMEM50A transmembrane protein 50A -1.44566
PPP1R8 protein phosphatase 1, regulatory subunit 8 -1.4405
SP1 Sp1 transcription factor -1.44011
VIM vimentin -1.43909
ZNF304 zinc finger protein 304 -1.43907
GOLGA2P5 golgin A2 pseudogene 5 -1.43658
MKKS McKusick-Kaufman syndrome -1.43614
SSPN sarcospan -1.43422
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 -1.43181
RNF138 ring finger protein 138, E3 ubiquitin protein ligase -1.4275
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 -1.42367
KCNMB4 potassium channel subfamily M regulatory beta subunit 4 -1.42258
OCEL1 occludin/ELL domain containing 1 -1.42228
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 -1.42046
VN1R1 vomeronasal 1 receptor 1 -1.4166
PAX1 paired box 1 -1.41648