NCI-H747 Gene Set

Dataset COSMIC Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description disease: colorectal adenocarcinoma (Cell Line Ontology, CLO_0008114)
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314 genes mutated in the NCI-H747 cell line from the COSMIC Cell Line Gene Mutation Profiles dataset.

Symbol Name
AATK apoptosis-associated tyrosine kinase
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3
ABLIM1 actin binding LIM protein 1
ADAM21 ADAM metallopeptidase domain 21
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADCY10 adenylate cyclase 10 (soluble)
ADCY8 adenylate cyclase 8 (brain)
ADGRG4 adhesion G protein-coupled receptor G4
ADGRG7 adhesion G protein-coupled receptor G7
ADGRL3 adhesion G protein-coupled receptor L3
ADORA2A adenosine A2a receptor
ADRB2 adrenoceptor beta 2, surface
AGBL4 ATP/GTP binding protein-like 4
ALPK2 alpha-kinase 2
ANGPT2 angiopoietin 2
ANKRD46 ankyrin repeat domain 46
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A
ANO2 anoctamin 2, calcium activated chloride channel
ANO5 anoctamin 5
ANTXR1 anthrax toxin receptor 1
APC adenomatous polyposis coli
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18
ARID1B AT rich interactive domain 1B (SWI1-like)
ASCC3 activating signal cointegrator 1 complex subunit 3
ATE1 arginyltransferase 1
ATM ATM serine/threonine kinase
ATP13A3 ATPase type 13A3
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
AUTS2 autism susceptibility candidate 2
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BAHCC1 BAH domain and coiled-coil containing 1
BAIAP3 BAI1-associated protein 3
BCAP29 B-cell receptor-associated protein 29
CA10 carbonic anhydrase X
CADPS Ca++-dependent secretion activator
CBX8 chromobox homolog 8
CCDC88C coiled-coil domain containing 88C
CDCA7 cell division cycle associated 7
CDHR3 cadherin-related family member 3
CDHR5 cadherin-related family member 5
CDK14 cyclin-dependent kinase 14
CENPU centromere protein U
CLSTN3 calsyntenin 3
COL15A1 collagen, type XV, alpha 1
CR2 complement component (3d/Epstein Barr virus) receptor 2
CRYBB2 crystallin, beta B2
CSF3 colony stimulating factor 3 (granulocyte)
CST2 cystatin SA
CTAGE5 CTAGE family, member 5
CTTNBP2 cortactin binding protein 2
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
DAAM1 dishevelled associated activator of morphogenesis 1
DCAF4L2 DDB1 and CUL4 associated factor 4-like 2
DCST2 DC-STAMP domain containing 2
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
DHCR24 24-dehydrocholesterol reductase
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
DLGAP2 discs, large (Drosophila) homolog-associated protein 2
DNAH10 dynein, axonemal, heavy chain 10
DNAH17 dynein, axonemal, heavy chain 17
DNAH3 dynein, axonemal, heavy chain 3
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DPYSL3 dihydropyrimidinase-like 3
DRD1 dopamine receptor D1
DSEL dermatan sulfate epimerase-like
DSPP dentin sialophosphoprotein
EBF3 early B-cell factor 3
EGFL6 EGF-like-domain, multiple 6
EHBP1 EH domain binding protein 1
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4
EPRS glutamyl-prolyl-tRNA synthetase
ERI2 ERI1 exoribonuclease family member 2
ETV6 ets variant 6
EXTL3 exostosin-like glycosyltransferase 3
FAM126A family with sequence similarity 126, member A
FAM153B family with sequence similarity 153, member B
FAM90A1 family with sequence similarity 90, member A1
FANCC Fanconi anemia, complementation group C
FAT1 FAT atypical cadherin 1
FAT2 FAT atypical cadherin 2
FBXL7 F-box and leucine-rich repeat protein 7
FBXO39 F-box protein 39
FLG filaggrin
FN1 fibronectin 1
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FRAS1 Fraser extracellular matrix complex subunit 1
FRMPD2 FERM and PDZ domain containing 2
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
G6PC2 glucose-6-phosphatase, catalytic, 2
GAS2L2 growth arrest-specific 2 like 2
GCM2 glial cells missing homolog 2 (Drosophila)
GPC6 glypican 6
GPR75 G protein-coupled receptor 75
GPRC5A G protein-coupled receptor, class C, group 5, member A
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
HIP1R huntingtin interacting protein 1 related
HLTF helicase-like transcription factor
HRASLS HRAS-like suppressor
HYDIN HYDIN, axonemal central pair apparatus protein
IBSP integrin-binding sialoprotein
IFT172 intraflagellar transport 172
IGSF21 immunoglobin superfamily, member 21
ILF3 interleukin enhancer binding factor 3, 90kDa
INHA inhibin, alpha
INSC inscuteable homolog (Drosophila)
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
IWS1 IWS1 homolog (S. cerevisiae)
JMJD1C jumonji domain containing 1C
JPH3 junctophilin 3
KBTBD3 kelch repeat and BTB (POZ) domain containing 3
KDM4B lysine (K)-specific demethylase 4B
KIAA1671 KIAA1671
KIF2B kinesin family member 2B
KLHL30 kelch-like family member 30
KMT2C lysine (K)-specific methyltransferase 2C
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT16 keratin 16, type I
KRT17P1 keratin 17 pseudogene 1
KRT6A keratin 6A, type II
KRT78 keratin 78, type II
KRTAP10-9 keratin associated protein 10-9
LCE2B late cornified envelope 2B
LCE3E late cornified envelope 3E
LCTL lactase-like
LOXL3 lysyl oxidase-like 3
LPA lipoprotein, Lp(a)
LRMP lymphoid-restricted membrane protein
LRRK1 leucine-rich repeat kinase 1
LRRK2 leucine-rich repeat kinase 2
LRRTM1 leucine rich repeat transmembrane neuronal 1
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae)
MAGEE2 melanoma antigen family E2
MAN1A1 mannosidase, alpha, class 1A, member 1
MAPK12 mitogen-activated protein kinase 12
MBTPS1 membrane-bound transcription factor peptidase, site 1
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MIOS missing oocyte, meiosis regulator, homolog (Drosophila)
MKL1 megakaryoblastic leukemia (translocation) 1
MMP28 matrix metallopeptidase 28
MOGS mannosyl-oligosaccharide glucosidase
MPPED1 metallophosphoesterase domain containing 1
MRPS31 mitochondrial ribosomal protein S31
MTPAP mitochondrial poly(A) polymerase
MUC21 mucin 21, cell surface associated
MUC6 mucin 6, oligomeric mucus/gel-forming
MYH14 myosin, heavy chain 14, non-muscle
NAF1 nuclear assembly factor 1 ribonucleoprotein
NAGLU N-acetylglucosaminidase, alpha
NCAPD3 non-SMC condensin II complex, subunit D3
NCKAP1 NCK-associated protein 1
NCKAP5L NCK-associated protein 5-like
NCOR1 nuclear receptor corepressor 1
NEB nebulin
NEIL2 nei endonuclease VIII-like 2 (E. coli)
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NIPBL Nipped-B homolog (Drosophila)
NKX2-2 NK2 homeobox 2
NOTCH2NL notch 2 N-terminal like
NUDCD1 NudC domain containing 1
NUPL2 nucleoporin like 2
NUSAP1 nucleolar and spindle associated protein 1
OFD1 oral-facial-digital syndrome 1
OOSP2 oocyte secreted protein 2
OPHN1 oligophrenin 1
OPN3 opsin 3
OR10A5 olfactory receptor, family 10, subfamily A, member 5
OR10S1 olfactory receptor, family 10, subfamily S, member 1
OR2L3 olfactory receptor, family 2, subfamily L, member 3
OR2T33 olfactory receptor, family 2, subfamily T, member 33
OR51G1 olfactory receptor, family 51, subfamily G, member 1 (gene/pseudogene)
PALD1 phosphatase domain containing, paladin 1
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PARP14 poly (ADP-ribose) polymerase family, member 14
PCDH10 protocadherin 10
PCDH15 protocadherin-related 15
PCDH17 protocadherin 17
PCDHA6 protocadherin alpha 6
PCDHA8 protocadherin alpha 8
PCDHB10 protocadherin beta 10
PCDHB13 protocadherin beta 13
PCDHB4 protocadherin beta 4
PCDHGA6 protocadherin gamma subfamily A, 6
PCDHGA7 protocadherin gamma subfamily A, 7
PCLO piccolo presynaptic cytomatrix protein
PCSK6 proprotein convertase subtilisin/kexin type 6
PCSK7 proprotein convertase subtilisin/kexin type 7
PDE11A phosphodiesterase 11A
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PHKA1 phosphorylase kinase, alpha 1 (muscle)
PICALM phosphatidylinositol binding clathrin assembly protein
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PKD1L3 polycystic kidney disease 1-like 3
PLEK pleckstrin
PLEKHA7 pleckstrin homology domain containing, family A member 7
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2
PLEKHH1 pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
PLXNA4 plexin A4
PNPLA1 patatin-like phospholipase domain containing 1
POLQ polymerase (DNA directed), theta
PPAP2C phosphatidic acid phosphatase type 2C
PRAMEF11 PRAME family member 11
PRF1 perforin 1 (pore forming protein)
PRKCSH protein kinase C substrate 80K-H
PROK2 prokineticin 2
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
PSG6 pregnancy specific beta-1-glycoprotein 6
PTPRD protein tyrosine phosphatase, receptor type, D
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1
PTTG1 pituitary tumor-transforming 1
PZP pregnancy-zone protein
RABGAP1L RAB GTPase activating protein 1-like
RAD51AP1 RAD51 associated protein 1
RALY RALY heterogeneous nuclear ribonucleoprotein
RASSF9 Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
RBMXL3 RNA binding motif protein, X-linked-like 3
RC3H1 ring finger and CCCH-type domains 1
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit
RGL3 ral guanine nucleotide dissociation stimulator-like 3
RHBG Rh family, B glycoprotein (gene/pseudogene)
RNF181 ring finger protein 181
RPA4 replication protein A4, 30kDa
RTKN2 rhotekin 2
SAA1 serum amyloid A1
SARNP SAP domain containing ribonucleoprotein
SART3 squamous cell carcinoma antigen recognized by T cells 3
SCFD1 sec1 family domain containing 1
SCGB3A1 secretoglobin, family 3A, member 1
SEC14L4 SEC14-like 4 (S. cerevisiae)
SEC31B SEC31 homolog B (S. cerevisiae)
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SERINC4 serine incorporator 4
SF3B1 splicing factor 3b, subunit 1, 155kDa
SGCE sarcoglycan, epsilon
SH3BP5 SH3-domain binding protein 5 (BTK-associated)
SIPA1L2 signal-induced proliferation-associated 1 like 2
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC31A2 solute carrier family 31 (copper transporter), member 2
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SORCS1 sortilin-related VPS10 domain containing receptor 1
SP140L SP140 nuclear body protein-like
SPATS2 spermatogenesis associated, serine-rich 2
SPINK5 serine peptidase inhibitor, Kazal type 5
SPRED1 sprouty-related, EVH1 domain containing 1
SPRR2E small proline-rich protein 2E
STAR steroidogenic acute regulatory protein
STEAP4 STEAP family member 4
STK17A serine/threonine kinase 17a
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
SYNM synemin, intermediate filament protein
SYTL2 synaptotagmin-like 2
SZT2 seizure threshold 2 homolog (mouse)
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TBC1D4 TBC1 domain family, member 4
TBL1Y transducin (beta)-like 1, Y-linked
TBX5 T-box 5
TCEB3C transcription elongation factor B polypeptide 3C (elongin A3)
TCP11L2 t-complex 11, testis-specific-like 2
TDRD12 tudor domain containing 12
TEX14 testis expressed 14
THBS2 thrombospondin 2
TIMP2 TIMP metallopeptidase inhibitor 2
TM9SF2 transmembrane 9 superfamily member 2
TNNI3K TNNI3 interacting kinase
TOR1A torsin family 1, member A (torsin A)
TP53 tumor protein p53
TPO thyroid peroxidase
TRAPPC13 trafficking protein particle complex 13
TRIM48 tripartite motif containing 48
TRIM64B tripartite motif containing 64B
TRIM66 tripartite motif containing 66
TTBK2 tau tubulin kinase 2
TTC16 tetratricopeptide repeat domain 16
TTN titin
TTPA tocopherol (alpha) transfer protein
TUBGCP6 tubulin, gamma complex associated protein 6
TXNDC11 thioredoxin domain containing 11
TXNRD3 thioredoxin reductase 3
UBE2W ubiquitin-conjugating enzyme E2W (putative)
UNC80 unc-80 homolog (C. elegans)
USH2A Usher syndrome 2A (autosomal recessive, mild)
USHBP1 Usher syndrome 1C binding protein 1
USP2 ubiquitin specific peptidase 2
USP24 ubiquitin specific peptidase 24
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
VDAC3 voltage-dependent anion channel 3
VN1R1 vomeronasal 1 receptor 1
VWA5B2 von Willebrand factor A domain containing 5B2
WDR60 WD repeat domain 60
WIZ widely interspaced zinc finger motifs
WWC1 WW and C2 domain containing 1
ZBTB37 zinc finger and BTB domain containing 37
ZCCHC6 zinc finger, CCHC domain containing 6
ZFPM1 zinc finger protein, FOG family member 1
ZNF184 zinc finger protein 184
ZNF236 zinc finger protein 236
ZNF252P zinc finger protein 252, pseudogene
ZNF30 zinc finger protein 30
ZNF34 zinc finger protein 34
ZNF687 zinc finger protein 687
ZNF746 zinc finger protein 746
ZNF790 zinc finger protein 790
ZNF83 zinc finger protein 83
ZNF830 zinc finger protein 830
ZNRF3 zinc and ring finger 3