NCI-H727 Gene Set

Dataset Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description disease: carcinoid (Cell Line Ontology, CLO_0008111)
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217 genes mutated in the NCI-H727 cell line from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles dataset.

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADAM10 ADAM metallopeptidase domain 10
ADGRG1 adhesion G protein-coupled receptor G1
ADGRV1 adhesion G protein-coupled receptor V1
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AKAP6 A kinase (PRKA) anchor protein 6
ALDH16A1 aldehyde dehydrogenase 16 family, member A1
ALMS1 Alstrom syndrome protein 1
AMER3 APC membrane recruitment protein 3
ANKRD27 ankyrin repeat domain 27 (VPS9 domain)
ANKS6 ankyrin repeat and sterile alpha motif domain containing 6
AP1G1 adaptor-related protein complex 1, gamma 1 subunit
AP3B1 adaptor-related protein complex 3, beta 1 subunit
APMAP adipocyte plasma membrane associated protein
ARHGAP39 Rho GTPase activating protein 39
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATG2B autophagy related 2B
ATP8B3 ATPase, aminophospholipid transporter, class I, type 8B, member 3
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BAZ2B bromodomain adjacent to zinc finger domain, 2B
BCAT1 branched chain amino-acid transaminase 1, cytosolic
BCHE butyrylcholinesterase
BCOR BCL6 corepressor
BICD1 bicaudal D homolog 1 (Drosophila)
BPTF bromodomain PHD finger transcription factor
BRAT1 BRCA1-associated ATM activator 1
BRCA1 breast cancer 1, early onset
BRD4 bromodomain containing 4
BSN bassoon presynaptic cytomatrix protein
BUD13 BUD13 homolog (S. cerevisiae)
C11ORF63 chromosome 11 open reading frame 63
C14ORF169 chromosome 14 open reading frame 169
C2ORF76 chromosome 2 open reading frame 76
CACNA2D4 calcium channel, voltage-dependent, alpha 2/delta subunit 4
CALCB calcitonin-related polypeptide beta
CAPN10 calpain 10
CAPRIN2 caprin family member 2
CCDC150 coiled-coil domain containing 150
CCDC93 coiled-coil domain containing 93
CDC73 cell division cycle 73
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CDHR2 cadherin-related family member 2
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3
CEMIP cell migration inducing protein, hyaluronan binding
CEP250 centrosomal protein 250kDa
CHD5 chromodomain helicase DNA binding protein 5
CKAP2 cytoskeleton associated protein 2
CLCN3 chloride channel, voltage-sensitive 3
CLDN4 claudin 4
CLINT1 clathrin interactor 1
CNOT1 CCR4-NOT transcription complex, subunit 1
CNTRL centriolin
COG3 component of oligomeric golgi complex 3
COL12A1 collagen, type XII, alpha 1
COL18A1 collagen, type XVIII, alpha 1
COL21A1 collagen, type XXI, alpha 1
CREBRF CREB3 regulatory factor
CTNS cystinosin, lysosomal cystine transporter
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DCAF10 DDB1 and CUL4 associated factor 10
DIDO1 death inducer-obliterator 1
DRAM2 DNA-damage regulated autophagy modulator 2
DTNB dystrobrevin, beta
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1
ECD ecdysoneless homolog (Drosophila)
ECE2 endothelin converting enzyme 2
EGLN3 egl-9 family hypoxia-inducible factor 3
EMID1 EMI domain containing 1
EPHB2 EPH receptor B2
EPHB6 EPH receptor B6
EPHX4 epoxide hydrolase 4
F2 coagulation factor II (thrombin)
FA2H fatty acid 2-hydroxylase
FAM111A family with sequence similarity 111, member A
FAM189A1 family with sequence similarity 189, member A1
FAM65C family with sequence similarity 65, member C
FBXO38 F-box protein 38
FCHSD1 FCH and double SH3 domains 1
FILIP1L filamin A interacting protein 1-like
FOXF1 forkhead box F1
FRK fyn-related Src family tyrosine kinase
FSTL5 follistatin-like 5
GALNT13 polypeptide N-acetylgalactosaminyltransferase 13
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GLDC glycine dehydrogenase (decarboxylating)
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GRIA3 glutamate receptor, ionotropic, AMPA 3
HELZ2 helicase with zinc finger 2, transcriptional coactivator
HIRA histone cell cycle regulator
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HKR1 HKR1, GLI-Kruppel zinc finger family member
HOMER2 homer scaffolding protein 2
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha
IGF2R insulin-like growth factor 2 receptor
INTS3 integrator complex subunit 3
IQGAP2 IQ motif containing GTPase activating protein 2
ITLN1 intelectin 1 (galactofuranose binding)
JAG1 jagged 1
KCNH8 potassium channel, voltage gated eag related subfamily H, member 8
KCTD16 potassium channel tetramerization domain containing 16
KDM5A lysine (K)-specific demethylase 5A
KDM5B lysine (K)-specific demethylase 5B
KIAA0355 KIAA0355
KIAA1147 KIAA1147
KIRREL kin of IRRE like (Drosophila)
KLF4 Kruppel-like factor 4 (gut)
KPTN kaptin (actin binding protein)
KRAS Kirsten rat sarcoma viral oncogene homolog
LAT2 linker for activation of T cells family, member 2
LHX4 LIM homeobox 4
LIN7B lin-7 homolog B (C. elegans)
LMBRD1 LMBR1 domain containing 1
LMBRD2 LMBR1 domain containing 2
LRRC16A leucine rich repeat containing 16A
LRRCC1 leucine rich repeat and coiled-coil centrosomal protein 1
MAP7D2 MAP7 domain containing 2
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MARCH4 membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
MARVELD3 MARVEL domain containing 3
MAST4 microtubule associated serine/threonine kinase family member 4
MAU2 MAU2 sister chromatid cohesion factor
MED14 mediator complex subunit 14
MEGF6 multiple EGF-like-domains 6
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MRPL44 mitochondrial ribosomal protein L44
MTERF3 mitochondrial transcription termination factor 3
MTO1 mitochondrial tRNA translation optimization 1
MUC2 mucin 2, oligomeric mucus/gel-forming
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
MYO1C myosin IC
MYO7B myosin VIIB
MYO9A myosin IXA
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NCAPH non-SMC condensin I complex, subunit H
NCOA7 nuclear receptor coactivator 7
NEK7 NIMA-related kinase 7
NOC4L nucleolar complex associated 4 homolog (S. cerevisiae)
NPHP1 nephronophthisis 1 (juvenile)
OAT ornithine aminotransferase
PCDHAC1 protocadherin alpha subfamily C, 1
PCDHGB2 protocadherin gamma subfamily B, 2
PCDHGC3 protocadherin gamma subfamily C, 3
PCSK6 proprotein convertase subtilisin/kexin type 6
PCYT1B phosphate cytidylyltransferase 1, choline, beta
PEX2 peroxisomal biogenesis factor 2
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
PHF14 PHD finger protein 14
PHKA1 phosphorylase kinase, alpha 1 (muscle)
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit
POMT2 protein-O-mannosyltransferase 2
PPAP2C phosphatidic acid phosphatase type 2C
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
PPP1R8 protein phosphatase 1, regulatory subunit 8
PRMT9 protein arginine methyltransferase 9
PSEN2 presenilin 2
PUS1 pseudouridylate synthase 1
PYCRL pyrroline-5-carboxylate reductase-like
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAB11FIP2 RAB11 family interacting protein 2 (class I)
RALGDS ral guanine nucleotide dissociation stimulator
RARB retinoic acid receptor, beta
RHEB Ras homolog enriched in brain
RHNO1 RAD9-HUS1-RAD1 interacting nuclear orphan 1
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
SBK3 SH3 domain binding kinase family, member 3
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SESTD1 SEC14 and spectrin domains 1
SETBP1 SET binding protein 1
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SH3RF2 SH3 domain containing ring finger 2
SLC26A10 solute carrier family 26, member 10
SLC44A4 solute carrier family 44, member 4
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
SNX9 sorting nexin 9
SOAT1 sterol O-acyltransferase 1
SPCS3 signal peptidase complex subunit 3 homolog (S. cerevisiae)
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
STK11 serine/threonine kinase 11
SURF4 surfeit 4
SYNJ2 synaptojanin 2
TAF1L TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like
TAOK2 TAO kinase 2
THAP4 THAP domain containing 4
TIGD1 tigger transposable element derived 1
TLR4 toll-like receptor 4
TMEM218 transmembrane protein 218
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TNIK TRAF2 and NCK interacting kinase
TNS3 tensin 3
TOP1MT topoisomerase (DNA) I, mitochondrial
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1
TRERF1 transcriptional regulating factor 1
TRIM11 tripartite motif containing 11
TRIM29 tripartite motif containing 29
TRIM9 tripartite motif containing 9
TRPM7 transient receptor potential cation channel, subfamily M, member 7
UBAP1 ubiquitin associated protein 1
UBXN4 UBX domain protein 4
USP28 ubiquitin specific peptidase 28
USP54 ubiquitin specific peptidase 54
UTRN utrophin
VTN vitronectin
WDR17 WD repeat domain 17
WDR47 WD repeat domain 47
WFDC10A WAP four-disulfide core domain 10A
WRN Werner syndrome, RecQ helicase-like
ZGRF1 zinc finger, GRF-type containing 1
ZNF175 zinc finger protein 175
ZNF37A zinc finger protein 37A
ZNF654 zinc finger protein 654
ZSCAN18 zinc finger and SCAN domain containing 18
ZSWIM4 zinc finger, SWIM-type containing 4