NCI-H716 Gene Set

Dataset COSMIC Cell Line Gene Mutation Profiles
Category genomics
Type cell line
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Genes

425 genes mutated in the NCI-H716 cell line from the COSMIC Cell Line Gene Mutation Profiles dataset.

Symbol Name
ABCA13 ATP-binding cassette, sub-family A (ABC1), member 13
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5
ABHD11 abhydrolase domain containing 11
ABHD17A abhydrolase domain containing 17A
ACD adrenocortical dysplasia homolog (mouse)
ACLY ATP citrate lyase
ACR acrosin
ADAM22 ADAM metallopeptidase domain 22
ADGRE3 adhesion G protein-coupled receptor E3
ADGRF2 adhesion G protein-coupled receptor F2
ADGRL4 adhesion G protein-coupled receptor L4
ADRA2A adrenoceptor alpha 2A
AFF1 AF4/FMR2 family, member 1
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AGPS alkylglycerone phosphate synthase
AGTR2 angiotensin II receptor, type 2
AHDC1 AT hook, DNA binding motif, containing 1
AKAP8L A kinase (PRKA) anchor protein 8-like
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
ALOX15 arachidonate 15-lipoxygenase
ALPK2 alpha-kinase 2
ALPK3 alpha-kinase 3
AMZ1 archaelysin family metallopeptidase 1
ANAPC7 anaphase promoting complex subunit 7
ANK2 ankyrin 2, neuronal
ANKRD62 ankyrin repeat domain 62
ANO3 anoctamin 3
ANXA3 annexin A3
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
APOB apolipoprotein B
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
ARFGAP2 ADP-ribosylation factor GTPase activating protein 2
ARMC4 armadillo repeat containing 4
ARMC9 armadillo repeat containing 9
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ASIC2 acid sensing (proton gated) ion channel 2
ATG4A autophagy related 4A, cysteine peptidase
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
ATP7A ATPase, Cu++ transporting, alpha polypeptide
ATR ATR serine/threonine kinase
B3GALTL beta 1,3-galactosyltransferase-like
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BAHD1 bromo adjacent homology domain containing 1
BCL2L12 BCL2-like 12 (proline rich)
BRD8 bromodomain containing 8
BRSK1 BR serine/threonine kinase 1
BTN3A1 butyrophilin, subfamily 3, member A1
C5 complement component 5
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CAPN13 calpain 13
CCDC132 coiled-coil domain containing 132
CCDC38 coiled-coil domain containing 38
CCNB3 cyclin B3
CD1B CD1b molecule
CD2AP CD2-associated protein
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH12 cadherin 12, type 2 (N-cadherin 2)
CDH19 cadherin 19, type 2
CDH26 cadherin 26
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CENPO centromere protein O
CEP170 centrosomal protein 170kDa
CEP290 centrosomal protein 290kDa
CFAP58 cilia and flagella associated protein 58
CFHR4 complement factor H-related 4
CGNL1 cingulin-like 1
CHD8 chromodomain helicase DNA binding protein 8
CHD9 chromodomain helicase DNA binding protein 9
CHST6 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6
CIC capicua transcriptional repressor
CLCA1 chloride channel accessory 1
CLCA2 chloride channel accessory 2
CLEC4E C-type lectin domain family 4, member E
CLEC4F C-type lectin domain family 4, member F
CLIP2 CAP-GLY domain containing linker protein 2
CLMP CXADR-like membrane protein
CLUL1 clusterin-like 1 (retinal)
CMPK2 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
CMYA5 cardiomyopathy associated 5
CNPPD1 cyclin Pas1/PHO80 domain containing 1
COL20A1 collagen, type XX, alpha 1
COL5A2 collagen, type V, alpha 2
COL6A3 collagen, type VI, alpha 3
COL9A1 collagen, type IX, alpha 1
COL9A3 collagen, type IX, alpha 3
CSMD3 CUB and Sushi multiple domains 3
CSN1S1 casein alpha s1
CTAGE5 CTAGE family, member 5
CTNNA3 catenin (cadherin-associated protein), alpha 3
CTTNBP2NL CTTNBP2 N-terminal like
CUBN cubilin (intrinsic factor-cobalamin receptor)
CWC22 CWC22 spliceosome-associated protein
CYP27C1 cytochrome P450, family 27, subfamily C, polypeptide 1
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7
CYP4X1 cytochrome P450, family 4, subfamily X, polypeptide 1
DARS aspartyl-tRNA synthetase
DEFB119 defensin, beta 119
DENND1C DENN/MADD domain containing 1C
DENND4A DENN/MADD domain containing 4A
DHX33 DEAH (Asp-Glu-Ala-His) box polypeptide 33
DMXL1 Dmx-like 1
DNAH1 dynein, axonemal, heavy chain 1
DNAH11 dynein, axonemal, heavy chain 11
DNAH14 dynein, axonemal, heavy chain 14
DNAH5 dynein, axonemal, heavy chain 5
DNAH8 dynein, axonemal, heavy chain 8
DPY19L1 dpy-19-like 1 (C. elegans)
DSCR4 Down syndrome critical region 4
DSG1 desmoglein 1
DZIP1L DAZ interacting zinc finger protein 1-like
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1
ELAC1 elaC ribonuclease Z 1
EMC1 ER membrane protein complex subunit 1
EP400 E1A binding protein p400
EPGN epithelial mitogen
EPHB4 EPH receptor B4
ESR2 estrogen receptor 2 (ER beta)
ETFDH electron-transferring-flavoprotein dehydrogenase
FADD Fas (TNFRSF6)-associated via death domain
FAM129B family with sequence similarity 129, member B
FAM135A family with sequence similarity 135, member A
FAM186B family with sequence similarity 186, member B
FAM47C family with sequence similarity 47, member C
FANCM Fanconi anemia, complementation group M
FAT3 FAT atypical cadherin 3
FBLN2 fibulin 2
FBXO42 F-box protein 42
FBXO46 F-box protein 46
FCGBP Fc fragment of IgG binding protein
FITM1 fat storage-inducing transmembrane protein 1
FNDC1 fibronectin type III domain containing 1
FOXC2 forkhead box C2
FOXR1 forkhead box R1
FYB FYN binding protein
GANC glucosidase, alpha; neutral C
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GAR1 GAR1 ribonucleoprotein
GBP7 guanylate binding protein 7
GDNF glial cell derived neurotrophic factor
GH2 growth hormone 2
GIGYF1 GRB10 interacting GYF protein 1
GLI2 GLI family zinc finger 2
GLUD2 glutamate dehydrogenase 2
GOLGA4 golgin A4
GPR141 G protein-coupled receptor 141
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
GREB1L growth regulation by estrogen in breast cancer-like
GRIK2 glutamate receptor, ionotropic, kainate 2
GRK1 G protein-coupled receptor kinase 1
GRM1 glutamate receptor, metabotropic 1
GTF2IRD2 GTF2I repeat domain containing 2
GTF2IRD2B GTF2I repeat domain containing 2B
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
GYLTL1B glycosyltransferase-like 1B
HEATR5B HEAT repeat containing 5B
HMCN1 hemicentin 1
HMGN2 high mobility group nucleosomal binding domain 2
HPS3 Hermansky-Pudlak syndrome 3
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
HTR3D 5-hydroxytryptamine (serotonin) receptor 3D, ionotropic
HTT huntingtin
HYDIN HYDIN, axonemal central pair apparatus protein
IGF2R insulin-like growth factor 2 receptor
IL12A interleukin 12A
IL12RB2 interleukin 12 receptor, beta 2
IL6ST interleukin 6 signal transducer
INPP5J inositol polyphosphate-5-phosphatase J
INPPL1 inositol polyphosphate phosphatase-like 1
INTS1 integrator complex subunit 1
INTS5 integrator complex subunit 5
IQGAP3 IQ motif containing GTPase activating protein 3
IREB2 iron-responsive element binding protein 2
ISM2 isthmin 2
ITGA6 integrin, alpha 6
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KCNK10 potassium channel, two pore domain subfamily K, member 10
KHK ketohexokinase (fructokinase)
KIAA0196 KIAA0196
KIAA0232 KIAA0232
KIAA0556 KIAA0556
KIAA1024 KIAA1024
KIAA1191 KIAA1191
KIAA1328 KIAA1328
KIF17 kinesin family member 17
KIF26B kinesin family member 26B
KLHL17 kelch-like family member 17
KLK2 kallikrein-related peptidase 2
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT10 keratin 10, type I
KRTAP23-1 keratin associated protein 23-1
LIM2 lens intrinsic membrane protein 2, 19kDa
LOXHD1 lipoxygenase homology domains 1
LOXL4 lysyl oxidase-like 4
LRRC18 leucine rich repeat containing 18
LRRCC1 leucine rich repeat and coiled-coil centrosomal protein 1
LTBP1 latent transforming growth factor beta binding protein 1
LYST lysosomal trafficking regulator
MADD MAP-kinase activating death domain
MAGEA10 melanoma antigen family A10
MAGEC1 melanoma antigen family C1
MAPK13 mitogen-activated protein kinase 13
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MARCH11 membrane-associated ring finger (C3HC4) 11
MAST4 microtubule associated serine/threonine kinase family member 4
MBTPS1 membrane-bound transcription factor peptidase, site 1
MCAM melanoma cell adhesion molecule
MCF2L MCF.2 cell line derived transforming sequence-like
MCF2L2 MCF.2 cell line derived transforming sequence-like 2
MCMDC2 minichromosome maintenance domain containing 2
MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2
METTL9 methyltransferase like 9
MICALCL MICAL C-terminal like
MMP2 matrix metallopeptidase 2
MOB1B MOB kinase activator 1B
MOV10 Mov10 RISC complex RNA helicase
MOXD1 monooxygenase, DBH-like 1
MPHOSPH10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
MTCL1 microtubule crosslinking factor 1
MUC12 mucin 12, cell surface associated
MUC16 mucin 16, cell surface associated
MUC19 mucin 19, oligomeric
MUC2 mucin 2, oligomeric mucus/gel-forming
MUC4 mucin 4, cell surface associated
MYBPC3 myosin binding protein C, cardiac
MYH1 myosin, heavy chain 1, skeletal muscle, adult
MYH11 myosin, heavy chain 11, smooth muscle
MYH7B myosin, heavy chain 7B, cardiac muscle, beta
MYOM3 myomesin 3
NARFL nuclear prelamin A recognition factor-like
NBAS neuroblastoma amplified sequence
NBPF9 neuroblastoma breakpoint family, member 9
NCKAP5 NCK-associated protein 5
NCOR2 nuclear receptor corepressor 2
NEB nebulin
NEDD1 neural precursor cell expressed, developmentally down-regulated 1
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NES nestin
NETO1 neuropilin (NRP) and tolloid (TLL)-like 1
NIPBL Nipped-B homolog (Drosophila)
NKTR natural killer cell triggering receptor
NME8 NME/NM23 family member 8
NPAS3 neuronal PAS domain protein 3
NPHP4 nephronophthisis 4
NPHS1 nephrosis 1, congenital, Finnish type (nephrin)
NRP1 neuropilin 1
NRXN1 neurexin 1
NSA2 NSA2 ribosome biogenesis homolog (S. cerevisiae)
NSUN5P2 NOP2/Sun domain family, member 5 pseudogene 2
NTN5 netrin 5
NUTM2A NUT family member 2A
NUTM2D NUT family member 2D
OR10A7 olfactory receptor, family 10, subfamily A, member 7
OR2M5 olfactory receptor, family 2, subfamily M, member 5
OR4C3 olfactory receptor, family 4, subfamily C, member 3
OR4M1 olfactory receptor, family 4, subfamily M, member 1
OR52A5 olfactory receptor, family 52, subfamily A, member 5
OR52E6 olfactory receptor, family 52, subfamily E, member 6
OR6C3 olfactory receptor, family 6, subfamily C, member 3
OR8B2 olfactory receptor, family 8, subfamily B, member 2
ORAI2 ORAI calcium release-activated calcium modulator 2
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PARP12 poly (ADP-ribose) polymerase family, member 12
PCDH11X protocadherin 11 X-linked
PDE4B phosphodiesterase 4B, cAMP-specific
PDIA2 protein disulfide isomerase family A, member 2
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PDZD2 PDZ domain containing 2
PDZD9 PDZ domain containing 9
PEG3 paternally expressed 3
PIBF1 progesterone immunomodulatory binding factor 1
PITPNM2 phosphatidylinositol transfer protein, membrane-associated 2
PKD2L1 polycystic kidney disease 2-like 1
PLD1 phospholipase D1, phosphatidylcholine-specific
PLEKHS1 pleckstrin homology domain containing, family S member 1
PLIN4 perilipin 4
PNLIP pancreatic lipase
POLN polymerase (DNA directed) nu
POM121 POM121 transmembrane nucleoporin
PPFIA2 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
PPM1K protein phosphatase, Mg2+/Mn2+ dependent, 1K
PRAM1 PML-RARA regulated adaptor molecule 1
PRDM16 PR domain containing 16
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRKCQ protein kinase C, theta
PROX2 prospero homeobox 2
PROZ protein Z, vitamin K-dependent plasma glycoprotein
PRRC2C proline-rich coiled-coil 2C
PSD3 pleckstrin and Sec7 domain containing 3
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
PTCD2 pentatricopeptide repeat domain 2
PTPRB protein tyrosine phosphatase, receptor type, B
PTPRD protein tyrosine phosphatase, receptor type, D
RAB11B RAB11B, member RAS oncogene family
RAB3A RAB3A, member RAS oncogene family
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic)
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RARS arginyl-tRNA synthetase
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated)
RBM19 RNA binding motif protein 19
RBM25 RNA binding motif protein 25
RBM26 RNA binding motif protein 26
RCVRN recoverin
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis)
RECQL RecQ helicase-like
RECQL5 RecQ protein-like 5
RELN reelin
RIF1 replication timing regulatory factor 1
RNF17 ring finger protein 17
RNF43 ring finger protein 43
RPAP2 RNA polymerase II associated protein 2
RPGR retinitis pigmentosa GTPase regulator
RPS24 ribosomal protein S24
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
RRH retinal pigment epithelium-derived rhodopsin homolog
RSPO4 R-spondin 4
RXRG retinoid X receptor, gamma
RYR3 ryanodine receptor 3
SAMD1 sterile alpha motif domain containing 1
SCN1A sodium channel, voltage gated, type I alpha subunit
SCN9A sodium channel, voltage gated, type IX alpha subunit
SDC3 syndecan 3
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SETDB1 SET domain, bifurcated 1
SHE Src homology 2 domain containing E
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC38A7 solute carrier family 38, member 7
SLC6A16 solute carrier family 6, member 16
SLIT3 slit homolog 3 (Drosophila)
SLITRK1 SLIT and NTRK-like family, member 1
SMYD5 SMYD family member 5
SNTG2 syntrophin, gamma 2
SPAG17 sperm associated antigen 17
SPATA31A6 SPATA31 subfamily A, member 6
SPSB4 splA/ryanodine receptor domain and SOCS box containing 4
SPTA1 spectrin, alpha, erythrocytic 1
SPTBN1 spectrin, beta, non-erythrocytic 1
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
STAB2 stabilin 2
STARD13 StAR-related lipid transfer (START) domain containing 13
STARD8 StAR-related lipid transfer (START) domain containing 8
STK11IP serine/threonine kinase 11 interacting protein
STK40 serine/threonine kinase 40
STX3 syntaxin 3
STX5 syntaxin 5
SYNE1 spectrin repeat containing, nuclear envelope 1
SYNE2 spectrin repeat containing, nuclear envelope 2
SYNE3 spectrin repeat containing, nuclear envelope family member 3
SYNGR4 synaptogyrin 4
SYT16 synaptotagmin XVI
TAF1B TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa
TAOK2 TAO kinase 2
TAOK3 TAO kinase 3
TBC1D2 TBC1 domain family, member 2
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TBCD tubulin folding cofactor D
TBCK TBC1 domain containing kinase
TENM1 teneurin transmembrane protein 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TG thyroglobulin
TH tyrosine hydroxylase
THEG theg spermatid protein
TMEM132B transmembrane protein 132B
TMEM171 transmembrane protein 171
TMEM255B transmembrane protein 255B
TNR tenascin R
TP53 tumor protein p53
TP63 tumor protein p63
TPR translocated promoter region, nuclear basket protein
TRPC4 transient receptor potential cation channel, subfamily C, member 4
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TSPAN8 tetraspanin 8
TTC6 tetratricopeptide repeat domain 6
TTN titin
TXNDC11 thioredoxin domain containing 11
UBE3B ubiquitin protein ligase E3B
UNC80 unc-80 homolog (C. elegans)
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast)
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
UROC1 urocanate hydratase 1
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3)
USP6 ubiquitin specific peptidase 6
UTRN utrophin
VASH1 vasohibin 1
VEGFC vascular endothelial growth factor C
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae)
VWA3B von Willebrand factor A domain containing 3B
VWA5B1 von Willebrand factor A domain containing 5B1
WDR91 WD repeat domain 91
WHAMM WAS protein homolog associated with actin, golgi membranes and microtubules
WWP2 WW domain containing E3 ubiquitin protein ligase 2
XIRP2 xin actin binding repeat containing 2
YIPF1 Yip1 domain family, member 1
YLPM1 YLP motif containing 1
ZC3H8 zinc finger CCCH-type containing 8
ZFP28 ZFP28 zinc finger protein
ZFP42 ZFP42 zinc finger protein
ZFYVE9 zinc finger, FYVE domain containing 9
ZIC5 Zic family member 5
ZIM2 zinc finger, imprinted 2
ZNF205 zinc finger protein 205
ZNF236 zinc finger protein 236
ZNF268 zinc finger protein 268
ZNF318 zinc finger protein 318
ZNF335 zinc finger protein 335
ZNF407 zinc finger protein 407
ZNF423 zinc finger protein 423
ZNF487 zinc finger protein 487
ZNF516 zinc finger protein 516
ZNF530 zinc finger protein 530
ZNF536 zinc finger protein 536
ZNF587 zinc finger protein 587
ZNF618 zinc finger protein 618
ZNF667 zinc finger protein 667
ZNF780A zinc finger protein 780A
ZP4 zona pellucida glycoprotein 4
ZSCAN2 zinc finger and SCAN domain containing 2
ZSCAN25 zinc finger and SCAN domain containing 25
ZSWIM5 zinc finger, SWIM-type containing 5