NCI-H661 Gene Set

Dataset COSMIC Cell Line Gene CNV Profiles
Category genomics
Type cell line
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Genes

237 genes with high or low copy number in NCI-H661 relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.

high copy number

Symbol Name Standardized Value
SPATA5 spermatogenesis associated 5 4.51153
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta) 3.12177
TFAP2D transcription factor AP-2 delta (activating enhancer binding protein 2 delta) 3.12177
EXOC1 exocyst complex component 1 2.93899
LOC644145 exocyst complex component 1 pseudogene 2.93899
CEP135 centrosomal protein 135kDa 2.93899
KIAA1211 KIAA1211 2.76305
RNA5SP411 RNA, 5S ribosomal pseudogene 411 2.76305
FLJ26245 uncharacterized LOC400533 2.76305
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 2.64759
FBXO9 F-box protein 9 2.64759
GSTA3 glutathione S-transferase alpha 3 2.64759
GSTA2 glutathione S-transferase alpha 2 2.64759
GSTA1 glutathione S-transferase alpha 1 2.64759
ICK intestinal cell (MAK-like) kinase 2.64759
GSTA4 glutathione S-transferase alpha 4 2.64759
GSTA5 glutathione S-transferase alpha 5 2.64759
GSTA7P glutathione S-transferase alpha 7, pseudogene 2.64759
GCM1 glial cells missing homolog 1 (Drosophila) 2.64759
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 2.64759
LRRC66 leucine rich repeat containing 66 2.64759
MIR4307 microRNA 4307 2.59653
PAQR8 progestin and adipoQ receptor family member VIII 2.59653
TRAM2-AS1 TRAM2 antisense RNA 1 (head to head) 2.59653
MIR133B microRNA 133b 2.59653
TMEM14A transmembrane protein 14A 2.59653
MIR206 microRNA 206 2.59653
LOC730101 uncharacterized LOC730101 2.59653
TRAM2 translocation associated membrane protein 2 2.59653
SPATA18 spermatogenesis associated 18 2.59653
IL17F interleukin 17F 2.49065
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive) 2.49065
MCM3 minichromosome maintenance complex component 3 2.49065
EFHC1 EF-hand domain (C-terminal) containing 1 2.49065
IL17A interleukin 17A 2.49065
CATSPERG catsper channel auxiliary subunit gamma 2.41451
LOC283914 2.41451
C19ORF33 chromosome 19 open reading frame 33 2.41451
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 2.41451
KCNK6 potassium channel, two pore domain subfamily K, member 6 2.41451
DPF1 D4, zinc and double PHD fingers family 1 2.41451
GGN gametogenetin 2.41451
YIF1B Yip1 interacting factor homolog B (S. cerevisiae) 2.41451
SPRED3 sprouty-related, EVH1 domain containing 3 2.41451
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A 2.41451
RASGRP4 RAS guanyl releasing protein 4 2.41451
SPINT2 serine peptidase inhibitor, Kunitz type, 2 2.41451
FAM98C family with sequence similarity 98, member C 2.41451
SYCN syncollin 2.39327
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4 2.39327
G2E3 G2/M-phase specific E3 ubiquitin protein ligase 2.39327
NCCRP1 non-specific cytotoxic cell receptor protein 1 homolog (zebrafish) 2.39327
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1 2.39327
CAPN12 calpain 12 2.39327
RYR1 ryanodine receptor 1 (skeletal) 2.39327
PAPL iron/zinc purple acid phosphatase-like protein 2.39327
EIF3K eukaryotic translation initiation factor 3, subunit K 2.39327
LGALS7 lectin, galactoside-binding, soluble, 7 2.39327
ACTN4 actinin, alpha 4 2.39327
IFNL3 interferon, lambda 3 2.39327
IFNL2 interferon, lambda 2 2.39327
IFNL4 interferon, lambda 4 (gene/pseudogene) 2.39327
LOC100505835 2.36889
LOC100506071 uncharacterized LOC100506071 2.36889
HNRNPL heterogeneous nuclear ribonucleoprotein L 2.36889
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 2.36889
RGS9BP regulator of G protein signaling 9 binding protein 2.36889
LOC400684 uncharacterized LOC400684 2.36889
SIRT2 sirtuin 2 2.36889
FBXO27 F-box protein 27 2.36889
ANKRD27 ankyrin repeat domain 27 (VPS9 domain) 2.36889
DPY19L3 dpy-19-like 3 (C. elegans) 2.36889
TDRD12 tudor domain containing 12 2.36889
ZNF507 zinc finger protein 507 2.36889
MRPS12 mitochondrial ribosomal protein S12 2.36889
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 2.36889
COCH cochlin 2.36889
FBXO17 F-box protein 17 2.36889
LINC00906 long intergenic non-protein coding RNA 906 2.36889
RINL Ras and Rab interactor-like 2.36889
ECH1 enoyl CoA hydratase 1, peroxisomal 2.36889
SCFD1 sec1 family domain containing 1 2.36889
SARS2 seryl-tRNA synthetase 2, mitochondrial 2.36889
PDCD5 programmed cell death 5 2.36889
ZNF781 zinc finger protein 781 2.36889
CFL2 cofilin 2 (muscle) 2.35236
PLD3 phospholipase D family, member 3 2.35236
LINC01551 long intergenic non-protein coding RNA 1551 2.35236
PRX periaxin 2.35236
HIPK4 homeodomain interacting protein kinase 4 2.35236
AP4S1 adaptor-related protein complex 4, sigma 1 subunit 2.35236
MIR624 microRNA 624 2.35236
NUDT19 nudix (nucleoside diphosphate linked moiety X)-type motif 19 2.35236
MIR641 microRNA 641 2.35236
FOXG1 forkhead box G1 2.35236
SNORD66 small nucleolar RNA, C/D box 66 2.35236
C19ORF47 chromosome 19 open reading frame 47 2.35236
PRKD1 protein kinase D1 2.35236
SERTAD1 SERTA domain containing 1 2.35236
EGLN3 egl-9 family hypoxia-inducible factor 3 2.35236
SERTAD3 SERTA domain containing 3 2.35236
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1 2.3178
FAM177A1 family with sequence similarity 177, member A1 2.3178
MAP3K10 mitogen-activated protein kinase kinase kinase 10 2.3178
EAPP E2F-associated phosphoprotein 2.3178
BAZ1A bromodomain adjacent to zinc finger domain, 1A 2.3178
AKT2 v-akt murine thymoma viral oncogene homolog 2 2.3178
IGBP1P1 immunoglobulin (CD79A) binding protein 1 pseudogene 1 2.3178
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 2.3178
SPTSSA serine palmitoyltransferase, small subunit A 2.3178
TTC9B tetratricopeptide repeat domain 9B 2.3178
SNX6 sorting nexin 6 2.3178
MIR548AI microRNA 548ai 2.3178
LRFN1 leucine rich repeat and fibronectin type III domain containing 1 2.3178
SRP54 signal recognition particle 54kDa 2.3178
CNTD2 cyclin N-terminal domain containing 2 2.3178
STRN3 striatin, calmodulin binding protein 3 2.3178
IFNL1 interferon, lambda 1 2.3178
GMFG glia maturation factor, gamma 2.30944
KIAA0391 KIAA0391 2.30944
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 2.30944
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma 2.30944
ZNF780A zinc finger protein 780A 2.30944
ZNF780B zinc finger protein 780B 2.30944
THEG5 testis highly expressed protein 5 2.30944
SELV selenoprotein V 2.283
EID2 EP300 interacting inhibitor of differentiation 2 2.283
GPR33 G protein-coupled receptor 33 (gene/pseudogene) 2.283
MED29 mediator complex subunit 29 2.283
RPS16 ribosomal protein S16 2.283
PLEKHG2 pleckstrin homology domain containing, family G (with RhoGef domain) member 2 2.283
AKAP6 A kinase (PRKA) anchor protein 6 2.283
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 2.283
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 2.283
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 2.283
FCGBP Fc fragment of IgG binding protein 2.283
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B 2.283
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) 2.283
TSHZ3 teashirt zinc finger homeobox 3 2.283
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae) 2.283
MIR4530 microRNA 4530 2.283
DLL3 delta-like 3 (Drosophila) 2.283
HEATR5A HEAT repeat containing 5A 2.283
ZNF546 zinc finger protein 546 2.283
EID2B EP300 interacting inhibitor of differentiation 2B 2.283
DTD2 D-tyrosyl-tRNA deacylase 2 (putative) 2.283
ZFP36 ZFP36 ring finger protein 2.283
FBL fibrillarin 2.283
LGALS13 lectin, galactoside-binding, soluble, 13 2.283
SAMD4B sterile alpha motif domain containing 4B 2.283
LEUTX leucine twenty homeobox 2.283
LGALS17A Charcot-Leyden crystal protein pseudogene 2.26395
CLC Charcot-Leyden crystal galectin 2.26395
LOC100129935 lectin, galactoside-binding, soluble, 14 pseudogene 2.26395
ARHGAP5 Rho GTPase activating protein 5 2.26395
NUBPL nucleotide binding protein-like 2.26395
BRMS1L breast cancer metastasis-suppressor 1-like 2.26395
ZNF536 zinc finger protein 536 2.26395
ARHGAP5-AS1 ARHGAP5 antisense RNA 1 (head to head) 2.26395
LGALS16 lectin, galactoside-binding, soluble, 16 2.26395
PTCSC3 papillary thyroid carcinoma susceptibility candidate 3 (non-protein coding) 2.26395
LINC00609 long intergenic non-protein coding RNA 609 2.26395
INSM2 insulinoma-associated 2 2.26395
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic) 2.26395
LGALS14 lectin, galactoside-binding, soluble, 14 2.26395
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1 2.25904
NKX2-8 NK2 homeobox 8 2.25904
POP4 processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae) 2.25904
NKX2-1 NK2 homeobox 1 2.25904
PAX9 paired box 9 2.25904
C19ORF12 chromosome 19 open reading frame 12 2.24845
MBIP MAP3K12 binding inhibitory protein 1 2.24845
SFTA3 surfactant associated 3 2.24845
VSTM2B V-set and transmembrane domain containing 2B 2.24139
LOC284395 uncharacterized LOC284395 2.24139
URI1 URI1, prefoldin-like chaperone 2.2355
CCNE1 cyclin E1 2.2355
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 2.2355
DPPA3 developmental pluripotency associated 3 2.22917
CCL28 chemokine (C-C motif) ligand 28 2.18124
LOC100132356 uncharacterized LOC100132356 2.18124
LOC153684 uncharacterized LOC153684 2.18124
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 2.18124
ZNF131 zinc finger protein 131 2.18124
LOC100506639 uncharacterized LOC100506639 2.18124
ANXA2R annexin A2 receptor 2.18124
LOC648987 uncharacterized LOC648987 2.18124
C5ORF28 chromosome 5 open reading frame 28 2.17694
C5ORF34 chromosome 5 open reading frame 34 2.17694
MRPS30 mitochondrial ribosomal protein S30 2.17694
SEPP1 selenoprotein P, plasma, 1 2.17694
PAIP1 poly(A) binding protein interacting protein 1 2.17694
CCDC152 coiled-coil domain containing 152 2.17694
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 2.16947
FGF10 fibroblast growth factor 10 2.16947
NNT nicotinamide nucleotide transhydrogenase 2.16816
UBE2MP1 ubiquitin-conjugating enzyme E2M pseudogene 1 2.12225
NOVA1 neuro-oncological ventral antigen 1 2.10038
LOC100130700 uncharacterized LOC100130700 2.08712
LOC146481 2.08712
LGALS4 lectin, galactoside-binding, soluble, 4 2.08334
LGALS7B lectin, galactoside-binding, soluble, 7B 2.08334
ZNF607 zinc finger protein 607 2.08021
LOC644554 uncharacterized LOC644554 2.08021
C8ORF22 chromosome 8 open reading frame 22 2.08021
SIPA1L3 signal-induced proliferation-associated 1 like 3 2.08021
ZNF573 zinc finger protein 573 2.08021
LOC100631378 uncharacterized 100631378 2.08021
WDR87 WD repeat domain 87 2.08021
SNAI2 snail family zinc finger 2 2.07776
NPAS3 neuronal PAS domain protein 3 2.0731
SMCO2 single-pass membrane protein with coiled-coil domains 2 2.05942
FGFR1OP2 FGFR1 oncogene partner 2 2.05864
TM7SF3 transmembrane 7 superfamily member 3 2.05864
MED21 mediator complex subunit 21 2.05864
C12ORF71 chromosome 12 open reading frame 71 2.05864
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2 2.05864
ASUN asunder spermatogenesis regulator 2.05778
STK38L serine/threonine kinase 38 like 2.05778
SSPN sarcospan 2.05635
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 2.0557
LINC00477 long intergenic non-protein coding RNA 477 2.05441
SOX5 SRY (sex determining region Y)-box 5 2.05408

low copy number

Symbol Name Standardized Value
ANKRD20A4 ankyrin repeat domain 20 family, member A4 -3.83684
FOXD4L6 forkhead box D4-like 6 -3.83684
CBWD6 COBW domain containing 6 -3.83684
LOC100133920 uncharacterized LOC100133920 -3.83684
LOC440896 uncharacterized LOC440896 -3.61078
PGM5P2 phosphoglucomutase 5 pseudogene 2 -3.57558
TMPRSS11E transmembrane protease, serine 11E -3.46155
FAM13A family with sequence similarity 13, member A -3.24687
LOC645166 lymphocyte-specific protein 1 pseudogene -3.18666
PARK2 parkin RBR E3 ubiquitin protein ligase -2.85647
SPATA31A6 SPATA31 subfamily A, member 6 -2.83114
DMD dystrophin -2.78077
CNTNAP3B contactin associated protein-like 3B -2.7778
ALG1L2 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase-like 2 -2.73329