NCI-H650 Gene Set

Dataset COSMIC Cell Line Gene CNV Profiles
Category genomics
Type cell line
Description disease: bronchioalveolar carci- noma; non-small cell lung cancer (lung primary) (Cell Line Ontology, CLO_0008101)
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Genes

332 genes with high or low copy number in NCI-H650 relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.

high copy number

Symbol Name Standardized Value
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9 3.12177
MIR4304 microRNA 4304 3.12177
LOC100507091 uncharacterized LOC100507091 3.12177
CDK2AP1 cyclin-dependent kinase 2 associated protein 1 3.12177
MIR143HG MIR143 host gene 3.12177
C12ORF65 chromosome 12 open reading frame 65 3.12177
PITPNM2 phosphatidylinositol transfer protein, membrane-associated 2 3.12177
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2 3.12177
MPHOSPH9 M-phase phosphoprotein 9 3.12177
MIR143 microRNA 143 3.12177
ARL6IP4 ADP-ribosylation factor-like 6 interacting protein 4 3.12177
TMED2 transmembrane emp24 domain trafficking protein 2 2.93899
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa 2.93899
SBNO1 strawberry notch homolog 1 (Drosophila) 2.93899
SNRNP35 small nuclear ribonucleoprotein 35kDa (U11/U12) 2.93899
RILPL1 Rab interacting lysosomal protein-like 1 2.93899
DDX55 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55 2.93899
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa 2.93899
MIR3908 microRNA 3908 2.93899
SETD8 SET domain containing (lysine methyltransferase) 8 2.93899
RILPL2 Rab interacting lysosomal protein-like 2 2.93899
KLRC3 killer cell lectin-like receptor subfamily C, member 3 2.64759
KLRC2 killer cell lectin-like receptor subfamily C, member 2 2.64759
KLRC4 killer cell lectin-like receptor subfamily C, member 4 2.64759
CLEC7A C-type lectin domain family 7, member A 2.64759
MAGOHB mago-nashi homolog B (Drosophila) 2.64759
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1 2.64759
PRB1 proline-rich protein BstNI subfamily 1 2.64759
NECAP1 NECAP endocytosis associated 1 2.64759
ACSM4 acyl-CoA synthetase medium-chain family member 4 2.64759
POU5F1P3 POU class 5 homeobox 1 pseudogene 3 2.64759
KLRD1 killer cell lectin-like receptor subfamily D, member 1 2.64759
CD163L1 CD163 molecule-like 1 2.64759
KLRAP1 killer cell lectin-like receptor subfamily A pseudogene 1 2.64759
TMEM52B transmembrane protein 52B 2.64759
KLRC4-KLRK1 KLRC4-KLRK1 readthrough 2.64759
KLRK1 killer cell lectin-like receptor subfamily K, member 1 2.64759
CD163 CD163 molecule 2.64759
PARP8 poly (ADP-ribose) polymerase family, member 8 2.64759
CLEC12B C-type lectin domain family 12, member B 2.64759
KLRC1 killer cell lectin-like receptor subfamily C, member 1 2.64759
PEX5 peroxisomal biogenesis factor 5 2.64759
CLSTN3 calsyntenin 3 2.64759
CLEC9A C-type lectin domain family 9, member A 2.64759
GABARAPL1 GABA(A) receptor-associated protein like 1 2.64759
CLEC1A C-type lectin domain family 1, member A 2.64759
FOXJ2 forkhead box J2 2.64759
STYK1 serine/threonine/tyrosine kinase 1 2.64759
CLEC4A C-type lectin domain family 4, member A 2.64759
C3AR1 complement component 3a receptor 1 2.64759
LINC00937 long intergenic non-protein coding RNA 937 2.59653
TAS2R14 taste receptor, type 2, member 14 2.59653
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 2.59653
CLEC6A C-type lectin domain family 6, member A 2.59653
TAS2R10 taste receptor, type 2, member 10 2.59653
PRH1 proline-rich protein HaeIII subfamily 1 2.59653
YBX3 Y box binding protein 3 2.59653
TAS2R8 taste receptor, type 2, member 8 2.59653
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 2.59653
TAS2R13 taste receptor, type 2, member 13 2.59653
PRH2 proline-rich protein HaeIII subfamily 2 2.59653
GDF3 growth differentiation factor 3 2.59653
PRB4 proline-rich protein BstNI subfamily 4 2.59653
TAS2R50 taste receptor, type 2, member 50 2.59653
CLEC4C C-type lectin domain family 4, member C 2.59653
CLEC4D C-type lectin domain family 4, member D 2.59653
PRB3 proline-rich protein BstNI subfamily 3 2.59653
TAS2R9 taste receptor, type 2, member 9 2.59653
NANOG Nanog homeobox 2.59653
NANOGP1 Nanog homeobox pseudogene 1 2.59653
NANOGNB NANOG neighbor homeobox 2.59653
PRR4 proline rich 4 (lacrimal) 2.59653
TAS2R7 taste receptor, type 2, member 7 2.59653
ETV6 ets variant 6 2.49065
RNU6-19P RNA, U6 small nuclear 19, pseudogene 2.49065
MANSC1 MANSC domain containing 1 2.49065
SLC2A14 solute carrier family 2 (facilitated glucose transporter), member 14 2.49065
LRP6 low density lipoprotein receptor-related protein 6 2.49065
LOH12CR2 loss of heterozygosity, 12, chromosomal region 2 (non-protein coding) 2.49065
LOH12CR1 loss of heterozygosity, 12, chromosomal region 1 2.44392
RPRD1B regulation of nuclear pre-mRNA domain containing 1B 2.44392
TGM2 transglutaminase 2 2.44392
BCL2L14 BCL2-like 14 (apoptosis facilitator) 2.44392
SNORA71C small nucleolar RNA, H/ACA box 71C 2.41451
LBP lipopolysaccharide binding protein 2.41451
RALGAPB Ral GTPase activating protein, beta subunit (non-catalytic) 2.41451
BPI bactericidal/permeability-increasing protein 2.41451
SNHG11 small nucleolar RNA host gene 11 2.41451
KIAA1755 KIAA1755 2.41451
SNORA71D small nucleolar RNA, H/ACA box 71D 2.41451
SNHG17 small nucleolar RNA host gene 17 2.41451
SNORA71A small nucleolar RNA, H/ACA box 71A 2.41451
SNORA71B small nucleolar RNA, H/ACA box 71B 2.41451
SRSF6 serine/arginine-rich splicing factor 6 2.3178
L3MBTL1 l(3)mbt-like 1 (Drosophila) 2.3178
SGK2 serum/glucocorticoid regulated kinase 2 2.3178
JPH2 junctophilin 2 2.30944
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 2.30944
IFT52 intraflagellar transport 52 2.30944
OSER1 oxidative stress responsive serine-rich 1 2.30944
OSER1-AS1 OSER1 antisense RNA 1 (head to head) 2.30944
GTSF1L gametocyte specific factor 1-like 2.30944
GDAP1L1 ganglioside induced differentiation associated protein 1-like 1 2.283
FITM2 fat storage-inducing transmembrane protein 2 2.283
TOX2 TOX high mobility group box family member 2 2.283
DPPA3 developmental pluripotency associated 3 2.22917
LPCAT1 lysophosphatidylcholine acyltransferase 1 2.21096
LOC728613 programmed cell death 6 pseudogene 2.21096
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 2.21096
SDHAP3 succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 3 2.21096
CSNK1A1 casein kinase 1, alpha 1 2.14116
CPNE8 copine VIII 2.12931
ALG10B ALG10B, alpha-1,2-glucosyltransferase 2.12931
LOC642846 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11-like 2.12703
DDX12P DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 12, pseudogene 2.12703
A2MP1 alpha-2-macroglobulin pseudogene 1 2.12225
PZP pregnancy-zone protein 2.12225
ZNF705A zinc finger protein 705A 2.11436
CD69 CD69 molecule 2.11167
KIF21A kinesin family member 21A 2.11167
PRB2 proline-rich protein BstNI subfamily 2 2.10992
KLRG1 killer cell lectin-like receptor subfamily G, member 1 2.10992
KLRB1 killer cell lectin-like receptor subfamily B, member 1 2.10992
KLRF2 killer cell lectin-like receptor subfamily F, member 2 2.10992
KLRF1 killer cell lectin-like receptor subfamily F, member 1 2.10992
A2ML1 alpha-2-macroglobulin-like 1 2.10992
CLEC2D C-type lectin domain family 2, member D 2.10992
A2M alpha-2-macroglobulin 2.10992
FAM86FP family with sequence similarity 86, member A pseudogene 2.10992
CLEC1B C-type lectin domain family 1, member B 2.10992
RIMKLB ribosomal modification protein rimK-like family member B 2.10992
FAM66C family with sequence similarity 66, member C 2.10992
LINC00612 long intergenic non-protein coding RNA 612 2.10992
CLEC12A C-type lectin domain family 12, member A 2.10992
CLECL1 C-type lectin-like 1 2.10992
FAM90A1 family with sequence similarity 90, member A1 2.10992
LOC374443 C-type lectin domain family 2, member D pseudogene 2.10992
PHC1 polyhomeotic homolog 1 (Drosophila) 2.10992
CLEC2A C-type lectin domain family 2, member A 2.10992
CLEC2B C-type lectin domain family 2, member B 2.10992
M6PR mannose-6-phosphate receptor (cation dependent) 2.10992
A2M-AS1 A2M antisense RNA 1 (head to head) 2.10992
TAS2R46 taste receptor, type 2, member 46 2.10317
TAS2R43 taste receptor, type 2, member 43 2.10177
TAS2R31 taste receptor, type 2, member 31 2.10177
TAS2R30 taste receptor, type 2, member 30 2.10177
TAS2R19 taste receptor, type 2, member 19 2.10177
MFAP5 microfibrillar associated protein 5 2.10038
AICDA activation-induced cytidine deaminase 2.10038
TAS2R20 taste receptor, type 2, member 20 2.10038
PRH1-PRR4 PRH1-PRR4 readthrough 2.10038
LOC100129361 2.10038
CLEC4E C-type lectin domain family 4, member E 2.10038
TAS2R42 taste receptor, type 2, member 42 2.10038
C12ORF40 chromosome 12 open reading frame 40 2.09529
ABCD2 ATP-binding cassette, sub-family D (ALD), member 2 2.09529
SLC2A13 solute carrier family 2 (facilitated glucose transporter), member 13 2.09117
MIR1244-1 microRNA 1244-1 2.09073
LRRK2 leucine-rich repeat kinase 2 2.08781
CNTN1 contactin 1 2.08334
MUC19 mucin 19, oligomeric 2.08066
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 2.06473
HLA-DRB6 major histocompatibility complex, class II, DR beta 6 (pseudogene) 2.06473
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 2.06473
SNORA75 small nucleolar RNA, H/ACA box 75 2.06233

low copy number

Symbol Name Standardized Value
USP51 ubiquitin specific peptidase 51 -3.53061
PAGE3 P antigen family, member 3 (prostate associated) -3.53061
MTRNR2L10 MT-RNR2-like 10 -3.53061
MIR4536-1 microRNA 4536-1 -3.53061
PAGE5 P antigen family, member 5 (prostate associated) -3.53061
ALAS2 5'-aminolevulinate synthase 2 -3.53061
APEX2 APEX nuclease (apurinic/apyrimidinic endonuclease) 2 -3.53061
MAGEH1 melanoma antigen family H1 -3.53061
FOXR2 forkhead box R2 -3.50611
PAGE2B P antigen family, member 2B -3.50611
TRO trophinin -3.50611
PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 -3.50611
PAGE2 P antigen family, member 2 (prostate associated) -3.50611
FAM104B family with sequence similarity 104, member B -3.50611
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9 -3.486
NPTX1 neuronal pentraxin I -3.2703
TENM1 teneurin transmembrane protein 1 -3.05196
FTHL17 ferritin, heavy polypeptide-like 17 -2.99615
GAGE2E G antigen 2E -2.9644
GAGE2D G antigen 2D -2.9644
GAGE2B G antigen 2B -2.9644
GSPT2 G1 to S phase transition 2 -2.9644
CENPVP1 centromere protein V pseudogene 1 -2.9644
GAGE2A G antigen 2A -2.9644
GAGE2C G antigen 2C -2.9644
GAGE12J G antigen 12J -2.9644
GAGE12D G antigen 12D -2.9644
GAGE4 G antigen 4 -2.9644
GAGE12F G antigen 12F -2.9644
GAGE1 G antigen 1 -2.9644
MAGED1 melanoma antigen family D1 -2.9644
GAGE13 G antigen 13 -2.9644
GAGE8 G antigen 8 -2.9644
MIRLET7F2 microRNA let-7f-2 -2.93929
RIBC1 RIB43A domain with coiled-coils 1 -2.93929
SMC1A structural maintenance of chromosomes 1A -2.93929
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like -2.93929
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 -2.93929
MIR98 microRNA 98 -2.93929
PLP2 proteolipid protein 2 (colonic epithelium-enriched) -2.93416
FOXP3 forkhead box P3 -2.93416
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2 -2.93416
MED14 mediator complex subunit 14 -2.93416
CXORF38 chromosome X open reading frame 38 -2.93416
PRICKLE3 prickle homolog 3 (Drosophila) -2.93416
MAGED2 melanoma antigen family D2 -2.93416
ITIH6 inter-alpha-trypsin inhibitor heavy chain family, member 6 -2.93416
USP27X ubiquitin specific peptidase 27, X-linked -2.93416
USP27X-AS1 USP27X antisense RNA 1 (head to head) -2.93416
PQBP1 polyglutamine binding protein 1 -2.93416
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) -2.93416
ERAS ES cell expressed Ras -2.93416
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit -2.93416
PPP1R3F protein phosphatase 1, regulatory subunit 3F -2.93416
TAB3 TGF-beta activated kinase 1/MAP3K7 binding protein 3 -2.93416
FAM47B family with sequence similarity 47, member B -2.93416
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked -2.93416
NYX nyctalopin -2.93416
GATA1 GATA binding protein 1 (globin transcription factor 1) -2.93416
RBM3 RNA binding motif (RNP1, RRM) protein 3 -2.93416
PAGE4 P antigen family, member 4 (prostate associated) -2.93416
WDR45 WD repeat domain 45 -2.93416
GPKOW G patch domain and KOW motifs -2.93416
PRAF2 PRA1 domain family, member 2 -2.93416
MAGIX MAGI family member, X-linked -2.93416
PAGE1 P antigen family, member 1 (prostate associated) -2.93416
CCDC22 coiled-coil domain containing 22 -2.93416
MAGED4B melanoma antigen family D4B -2.93416
WDR13 WD repeat domain 13 -2.93416
LOC100132831 A20-binding inhibitor of NF-kappaB activation 2 pseudogene -2.93416
MPC1L mitochondrial pyruvate carrier 1-like -2.93416
SYP synaptophysin -2.93416
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor -2.93416
PIM2 Pim-2 proto-oncogene, serine/threonine kinase -2.93416
GAGE10 G antigen 10 -2.93416
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2 -2.93416
HDAC6 histone deacetylase 6 -2.93416
SNORA11 small nucleolar RNA, H/ACA box 11 -2.92386
TSPYL2 TSPY-like 2 -2.91868
GPR173 G protein-coupled receptor 173 -2.91868
FAM156B family with sequence similarity 156, member B -2.91612
XAGE3 X antigen family, member 3 -2.91612
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase -2.91612
SSX8 synovial sarcoma, X breakpoint 8 -2.91612
SSX7 synovial sarcoma, X breakpoint 7 -2.91612
FGD1 FYVE, RhoGEF and PH domain containing 1 -2.91612
TSR2 TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) -2.91612
XAGE2 X antigen family, member 2 -2.91612
XAGE1B X antigen family, member 1B -2.91612
OTUD5 OTU deubiquitinase 5 -2.91268
SRPX sushi-repeat containing protein, X-linked -2.91268
TFE3 transcription factor binding to IGHM enhancer 3 -2.91268
GRIPAP1 GRIP1 associated protein 1 -2.91268
CCDC120 coiled-coil domain containing 120 -2.91268
BMP15 bone morphogenetic protein 15 -2.91268
MIR660 microRNA 660 -2.91268
MAGEB16 melanoma antigen family B16 -2.91268
TSPAN7 tetraspanin 7 -2.91268
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -2.91268
AKAP4 A kinase (PRKA) anchor protein 4 -2.91268
MIR500A microRNA 500a -2.91268
CCNB3 cyclin B3 -2.91268
KCND1 potassium channel, voltage gated Shal related subfamily D, member 1 -2.91268
MIR500B microRNA 500b -2.91268
SSX2B synovial sarcoma, X breakpoint 2B -2.91268
KRBOX4 KRAB box domain containing 4 -2.91268
WAS Wiskott-Aldrich syndrome -2.91268
MIR532 microRNA 532 -2.91268
ZNF674 zinc finger protein 674 -2.91268
CFAP47 cilia and flagella associated protein 47 -2.91268
SSX2 synovial sarcoma, X breakpoint 2 -2.91268
SYTL5 synaptotagmin-like 5 -2.91268
MIR502 microRNA 502 -2.91268
MIR188 microRNA 188 -2.91268
MIR501 microRNA 501 -2.91268
GLOD5 glyoxalase domain containing 5 -2.91268
SPANXN5 SPANX family, member N5 -2.91268
ZNF674-AS1 ZNF674 antisense RNA 1 (head to head) -2.91268
DYNLT3 dynein, light chain, Tctex-type 3 -2.91268
DGKK diacylglycerol kinase, kappa -2.91268
XAGE5 X antigen family, member 5 -2.91268
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 -2.91268
NUDT10 nudix (nucleoside diphosphate linked moiety X)-type motif 10 -2.91268
RPGR retinitis pigmentosa GTPase regulator -2.91268
MID1IP1 MID1 interacting protein 1 -2.91268
CLCN5 chloride channel, voltage-sensitive 5 -2.91268
MIR362 microRNA 362 -2.91268
USP9X ubiquitin specific peptidase 9, X-linked -2.91268
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 -2.91268
FAM156A family with sequence similarity 156, member A -2.89302
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1 -2.89201
LANCL3 LanC lantibiotic synthetase component C-like 3 (bacterial) -2.89201
IQSEC2 IQ motif and Sec7 domain 2 -2.89201
KDM5C lysine (K)-specific demethylase 5C -2.89201
SHROOM4 shroom family member 4 -2.88947
NDP Norrie disease (pseudoglioma) -2.88947
OTC ornithine carbamoyltransferase -2.88947
GPR34 G protein-coupled receptor 34 -2.88947
GPR82 G protein-coupled receptor 82 -2.88947
TMEM47 transmembrane protein 47 -2.88947
CYBB cytochrome b-245, beta polypeptide -2.88947
RP2 retinitis pigmentosa 2 (X-linked recessive) -2.88947
XK X-linked Kx blood group -2.88947
SNORA11D small nucleolar RNA, H/ACA box 11D -2.88947
MAGED4 melanoma antigen family D4 -2.88947
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 -2.88947
BCOR BCL6 corepressor -2.87802
FUNDC1 FUN14 domain containing 1 -2.87802
FAM47A family with sequence similarity 47, member A -2.87802
FTH1P18 ferritin, heavy polypeptide 1 pseudogene 18 -2.87269
MAOA monoamine oxidase A -2.87269
EFHC2 EF-hand domain (C-terminal) containing 2 -2.87269
PHF8 PHD finger protein 8 -2.86624
USP17L2 ubiquitin specific peptidase 17-like family member 2 -2.86624
WNK3 WNK lysine deficient protein kinase 3 -2.86624
FAM120C family with sequence similarity 120C -2.86624
MAOB monoamine oxidase B -2.86559
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) -2.86003
USP17L7 ubiquitin specific peptidase 17-like family member 7 -2.86003
FAM47C family with sequence similarity 47, member C -2.85574
DUSP21 dual specificity phosphatase 21 -2.85574
CXORF36 chromosome X open reading frame 36 -2.85574
HLA-H major histocompatibility complex, class I, H (pseudogene) -2.8504
HLA-J major histocompatibility complex, class I, J (pseudogene) -2.8473
KDM6A lysine (K)-specific demethylase 6A -2.84592
DMD dystrophin -2.78077
HCG4B HLA complex group 4B (non-protein coding) -2.75184