NCI-H522 Gene Set

Dataset COSMIC Cell Line Gene Mutation Profiles
Category genomics
Type cell line
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328 genes mutated in the NCI-H522 cell line from the COSMIC Cell Line Gene Mutation Profiles dataset.

Symbol Name
AADACL4 arylacetamide deacetylase-like 4
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4
ABI2 abl-interactor 2
ACTN1 actinin, alpha 1
ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 motif, 8
ADGRF3 adhesion G protein-coupled receptor F3
ADGRF5 adhesion G protein-coupled receptor F5
ADGRG4 adhesion G protein-coupled receptor G4
AHNAK2 AHNAK nucleoprotein 2
AK7 adenylate kinase 7
ALDH3B2 aldehyde dehydrogenase 3 family, member B2
AMD1 adenosylmethionine decarboxylase 1
ANKAR ankyrin and armadillo repeat containing
ANKRD30B ankyrin repeat domain 30B
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A
AOC2 amine oxidase, copper containing 2 (retina-specific)
AP3M1 adaptor-related protein complex 3, mu 1 subunit
APCDD1 adenomatosis polyposis coli down-regulated 1
APOL3 apolipoprotein L, 3
APTX aprataxin
AQR aquarius intron-binding spliceosomal factor
ARHGAP23 Rho GTPase activating protein 23
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ARMC4 armadillo repeat containing 4
ATF7 activating transcription factor 7
ATP13A3 ATPase type 13A3
ATP7A ATPase, Cu++ transporting, alpha polypeptide
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
AUNIP aurora kinase A and ninein interacting protein
BAIAP2L2 BAI1-associated protein 2-like 2
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BAZ2B bromodomain adjacent to zinc finger domain, 2B
BCOR BCL6 corepressor
BDKRB2 bradykinin receptor B2
BRDT bromodomain, testis-specific
C2CD2 C2 calcium-dependent domain containing 2
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit
CCDC117 coiled-coil domain containing 117
CCDC15 coiled-coil domain containing 15
CCDC57 coiled-coil domain containing 57
CCL11 chemokine (C-C motif) ligand 11
CD1C CD1c molecule
CD1D CD1d molecule
CD40LG CD40 ligand
CDC25C cell division cycle 25C
CDH23 cadherin-related 23
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CDK7 cyclin-dependent kinase 7
CDKL5 cyclin-dependent kinase-like 5
CELA2B chymotrypsin-like elastase family, member 2B
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2
CEP164 centrosomal protein 164kDa
CEP85L centrosomal protein 85kDa-like
CFAP46 cilia and flagella associated protein 46
CGN cingulin
CHD2 chromodomain helicase DNA binding protein 2
CHML choroideremia-like (Rab escort protein 2)
CKAP5 cytoskeleton associated protein 5
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
CNTN5 contactin 5
COL11A1 collagen, type XI, alpha 1
COLGALT2 collagen beta(1-O)galactosyltransferase 2
CPAMD8 C3 and PZP-like, alpha-2-macroglobulin domain containing 8
CPE carboxypeptidase E
CPNE1 copine I
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CRISP2 cysteine-rich secretory protein 2
CRYGS crystallin, gamma S
CSPP1 centrosome and spindle pole associated protein 1
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CWC27 CWC27 spliceosome-associated protein homolog (S. cerevisiae)
CXCR4 chemokine (C-X-C motif) receptor 4
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11
DCHS2 dachsous cadherin-related 2
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24
DGKB diacylglycerol kinase, beta 90kDa
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DNAH10 dynein, axonemal, heavy chain 10
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13
DOCK7 dedicator of cytokinesis 7
DOPEY2 dopey family member 2
DPPA4 developmental pluripotency associated 4
DSCAM Down syndrome cell adhesion molecule
E2F2 E2F transcription factor 2
EFHC1 EF-hand domain (C-terminal) containing 1
ELF2 E74-like factor 2 (ets domain transcription factor)
EML4 echinoderm microtubule associated protein like 4
ENAH enabled homolog (Drosophila)
ENGASE endo-beta-N-acetylglucosaminidase
ENO4 enolase family member 4
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4
EPHB4 EPH receptor B4
ERLIN2 ER lipid raft associated 2
EYS eyes shut homolog (Drosophila)
FAAH2 fatty acid amide hydrolase 2
FAM86B1 family with sequence similarity 86, member B1
FAT2 FAT atypical cadherin 2
FCGBP Fc fragment of IgG binding protein
FCMR Fc fragment of IgM receptor
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FDX1 ferredoxin 1
FGF10 fibroblast growth factor 10
FPR3 formyl peptide receptor 3
FRG2C FSHD region gene 2 family, member C
FYTTD1 forty-two-three domain containing 1
GAK cyclin G associated kinase
GLI2 GLI family zinc finger 2
GOPC golgi-associated PDZ and coiled-coil motif containing
GPR50 G protein-coupled receptor 50
GREB1L growth regulation by estrogen in breast cancer-like
GRID2 glutamate receptor, ionotropic, delta 2
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GRIP1 glutamate receptor interacting protein 1
GSN gelsolin
GTSF1 gametocyte specific factor 1
GUCY2C guanylate cyclase 2C
GYPC glycophorin C (Gerbich blood group)
HAVCR2 hepatitis A virus cellular receptor 2
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HMHB1 histocompatibility (minor) HB-1
HRNR hornerin
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HSPG2 heparan sulfate proteoglycan 2
IFT43 intraflagellar transport 43
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1
IGSF3 immunoglobulin superfamily, member 3
IKZF2 IKAROS family zinc finger 2 (Helios)
ILF3 interleukin enhancer binding factor 3, 90kDa
INADL InaD-like (Drosophila)
INF2 inverted formin, FH2 and WH2 domain containing
INTS6 integrator complex subunit 6
KCNA4 potassium channel, voltage gated shaker related subfamily A, member 4
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KDELC1 KDEL (Lys-Asp-Glu-Leu) containing 1
KIAA1468 KIAA1468
KIAA1671 KIAA1671
KIF18B kinesin family member 18B
KLHL6 kelch-like family member 6
KMT2D lysine (K)-specific methyltransferase 2D
KPRP keratinocyte proline-rich protein
KRT37 keratin 37, type I
KRTAP16-1 keratin associated protein 16-1
KRTAP3-1 keratin associated protein 3-1
KRTAP5-1 keratin associated protein 5-1
KRTAP9-2 keratin associated protein 9-2
KSR2 kinase suppressor of ras 2
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LDB3 LIM domain binding 3
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LGI3 leucine-rich repeat LGI family, member 3
LONP1 lon peptidase 1, mitochondrial
LRP1B low density lipoprotein receptor-related protein 1B
LRP2 low density lipoprotein receptor-related protein 2
LRRIQ1 leucine-rich repeats and IQ motif containing 1
LRRK2 leucine-rich repeat kinase 2
MAGEB10 melanoma antigen family B10
MAP2 microtubule-associated protein 2
MBNL1 muscleblind-like splicing regulator 1
MCM9 minichromosome maintenance complex component 9
MCOLN2 mucolipin 2
MED24 mediator complex subunit 24
MEF2D myocyte enhancer factor 2D
METTL11B methyltransferase like 11B
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MIOS missing oocyte, meiosis regulator, homolog (Drosophila)
MOGAT2 monoacylglycerol O-acyltransferase 2
MON1B MON1 secretory trafficking family member B
MROH2A maestro heat-like repeat family member 2A
MSH2 mutS homolog 2
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC12 mucin 12, cell surface associated
MUC4 mucin 4, cell surface associated
NAGK N-acetylglucosamine kinase
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative)
NCAPD3 non-SMC condensin II complex, subunit D3
NCF2 neutrophil cytosolic factor 2
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NEB nebulin
NEFL neurofilament, light polypeptide
NID1 nidogen 1
NKX2-6 NK2 homeobox 6
NLRP8 NLR family, pyrin domain containing 8
NOX4 NADPH oxidase 4
NPC1 Niemann-Pick disease, type C1
NPM3 nucleophosmin/nucleoplasmin 3
NRG3 neuregulin 3
NUP133 nucleoporin 133kDa
OLFM4 olfactomedin 4
OR14J1 olfactory receptor, family 14, subfamily J, member 1
OR56A1 olfactory receptor, family 56, subfamily A, member 1
OR5A2 olfactory receptor, family 5, subfamily A, member 2
OR5M9 olfactory receptor, family 5, subfamily M, member 9
OR5W2 olfactory receptor, family 5, subfamily W, member 2
OR6N2 olfactory receptor, family 6, subfamily N, member 2
OR8B4 olfactory receptor, family 8, subfamily B, member 4 (gene/pseudogene)
OR9G4 olfactory receptor, family 9, subfamily G, member 4
ORC1 origin recognition complex, subunit 1
OTOA otoancorin
PASK PAS domain containing serine/threonine kinase
PCDH15 protocadherin-related 15
PCDHB11 protocadherin beta 11
PDE3A phosphodiesterase 3A, cGMP-inhibited
PDE4D phosphodiesterase 4D, cAMP-specific
PDIA2 protein disulfide isomerase family A, member 2
PF4 platelet factor 4
PGAP3 post-GPI attachment to proteins 3
PGRMC2 progesterone receptor membrane component 2
PICALM phosphatidylinositol binding clathrin assembly protein
PJA1 praja ring finger 1, E3 ubiquitin protein ligase
PKD1L1 polycystic kidney disease 1 like 1
PKM pyruvate kinase, muscle
PLCB2 phospholipase C, beta 2
PLD5 phospholipase D family, member 5
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2
PLK3 polo-like kinase 3
POM121L2 POM121 transmembrane nucleoporin-like 2
POSTN periostin, osteoblast specific factor
PPIH peptidylprolyl isomerase H (cyclophilin H)
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PRB1 proline-rich protein BstNI subfamily 1
PRMT6 protein arginine methyltransferase 6
PRNP prion protein
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PVALB parvalbumin
QPCTL glutaminyl-peptide cyclotransferase-like
RAG1 recombination activating gene 1
RANBP2 RAN binding protein 2
RAP1B RAP1B, member of RAS oncogene family
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
REEP3 receptor accessory protein 3
RET ret proto-oncogene
RIMS2 regulating synaptic membrane exocytosis 2
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
RTN1 reticulon 1
RYR2 ryanodine receptor 2 (cardiac)
SCNN1D sodium channel, non voltage gated 1 delta subunit
SDC3 syndecan 3
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SETBP1 SET binding protein 1
SHROOM3 shroom family member 3
SIGLEC16 sialic acid binding Ig-like lectin 16 (gene/pseudogene)
SIK3 SIK family kinase 3
SIX2 SIX homeobox 2
SLC16A6 solute carrier family 16, member 6
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SLC7A3 solute carrier family 7 (cationic amino acid transporter, y+ system), member 3
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SOX4 SRY (sex determining region Y)-box 4
SPEN spen family transcriptional repressor
SPHKAP SPHK1 interactor, AKAP domain containing
SPTA1 spectrin, alpha, erythrocytic 1
STK11IP serine/threonine kinase 11 interacting protein
STK36 serine/threonine kinase 36
STXBP4 syntaxin binding protein 4
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae)
SYMPK symplekin
TAAR6 trace amine associated receptor 6
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TAGLN2 transgelin 2
TAS1R1 taste receptor, type 1, member 1
TAS2R8 taste receptor, type 2, member 8
TAS2R9 taste receptor, type 2, member 9
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1
TCEB3CL2 transcription elongation factor B polypeptide 3C-like 2
TCHH trichohyalin
TDP1 tyrosyl-DNA phosphodiesterase 1
TEX2 testis expressed 2
TFAP2D transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
TMEFF2 transmembrane protein with EGF-like and two follistatin-like domains 2
TMEM2 transmembrane protein 2
TMEM63B transmembrane protein 63B
TMTC4 transmembrane and tetratricopeptide repeat containing 4
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNNI1 troponin I type 1 (skeletal, slow)
TNP2 transition protein 2 (during histone to protamine replacement)
TNR tenascin R
TNS1 tensin 1
TNS4 tensin 4
TONSL tonsoku-like, DNA repair protein
TP53 tumor protein p53
TRIM15 tripartite motif containing 15
TRIM49C tripartite motif containing 49C
TRIP11 thyroid hormone receptor interactor 11
TRPM6 transient receptor potential cation channel, subfamily M, member 6
TSC22D4 TSC22 domain family, member 4
TSEN54 TSEN54 tRNA splicing endonuclease subunit
TTN titin
U2AF1 U2 small nuclear RNA auxiliary factor 1
UBAC2 UBA domain containing 2
UBQLN4 ubiquilin 4
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative)
UGT2B11 UDP glucuronosyltransferase 2 family, polypeptide B11
UNC45B unc-45 homolog B (C. elegans)
UNC5C unc-5 homolog C (C. elegans)
WDPCP WD repeat containing planar cell polarity effector
WDR26 WD repeat domain 26
WDR63 WD repeat domain 63
WNK2 WNK lysine deficient protein kinase 2
WTIP Wilms tumor 1 interacting protein
XPO4 exportin 4
XPOT exportin, tRNA
ZCCHC16 zinc finger, CCHC domain containing 16
ZDHHC16 zinc finger, DHHC-type containing 16
ZMIZ1 zinc finger, MIZ-type containing 1
ZNF212 zinc finger protein 212
ZNF236 zinc finger protein 236
ZNF251 zinc finger protein 251
ZNF280A zinc finger protein 280A
ZNF438 zinc finger protein 438
ZNF470 zinc finger protein 470
ZNF543 zinc finger protein 543
ZNF558 zinc finger protein 558
ZNF816 zinc finger protein 816
ZNF850 zinc finger protein 850
ZNF880 zinc finger protein 880
ZP1 zona pellucida glycoprotein 1 (sperm receptor)