NCI-H520 Gene Set

Dataset COSMIC Cell Line Gene Mutation Profiles
Category genomics
Type cell line
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Genes

445 genes mutated in the NCI-H520 cell line from the COSMIC Cell Line Gene Mutation Profiles dataset.

Symbol Name
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ABHD2 abhydrolase domain containing 2
ABHD8 abhydrolase domain containing 8
ACAD11 acyl-CoA dehydrogenase family, member 11
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
ACAT2 acetyl-CoA acetyltransferase 2
ACSBG2 acyl-CoA synthetase bubblegum family member 2
ACVR1B activin A receptor, type IB
ADAM11 ADAM metallopeptidase domain 11
ADAM2 ADAM metallopeptidase domain 2
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ADAMTSL2 ADAMTS-like 2
ADCY7 adenylate cyclase 7
ADCY8 adenylate cyclase 8 (brain)
ADGRB1 adhesion G protein-coupled receptor B1
ADGRF3 adhesion G protein-coupled receptor F3
ADRA1B adrenoceptor alpha 1B
AFAP1 actin filament associated protein 1
AFF3 AF4/FMR2 family, member 3
AFF4 AF4/FMR2 family, member 4
AFTPH aftiphilin
AGK acylglycerol kinase
AKAP9 A kinase (PRKA) anchor protein 9
AKR1D1 aldo-keto reductase family 1, member D1
AMHR2 anti-Mullerian hormone receptor, type II
ANKS3 ankyrin repeat and sterile alpha motif domain containing 3
ARHGAP28 Rho GTPase activating protein 28
ARMC5 armadillo repeat containing 5
ASTN2 astrotactin 2
ATG4A autophagy related 4A, cysteine peptidase
ATM ATM serine/threonine kinase
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2
AUTS2 autism susceptibility candidate 2
BDH2 3-hydroxybutyrate dehydrogenase, type 2
BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
BIRC6 baculoviral IAP repeat containing 6
BLK BLK proto-oncogene, Src family tyrosine kinase
BMP2K BMP2 inducible kinase
BRD4 bromodomain containing 4
CA5B carbonic anhydrase VB, mitochondrial
CABS1 calcium-binding protein, spermatid-specific 1
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CALN1 calneuron 1
CAND1 cullin-associated and neddylation-dissociated 1
CAPN11 calpain 11
CARD11 caspase recruitment domain family, member 11
CCNYL2 cyclin Y-like 2, pseudogene
CD1C CD1c molecule
CD2AP CD2-associated protein
CD5 CD5 molecule
CDADC1 cytidine and dCMP deaminase domain containing 1
CDC16 cell division cycle 16
CDH10 cadherin 10, type 2 (T2-cadherin)
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CDKN2A cyclin-dependent kinase inhibitor 2A
CEP152 centrosomal protein 152kDa
CEP55 centrosomal protein 55kDa
CFAP44 cilia and flagella associated protein 44
CFHR3 complement factor H-related 3
CHD7 chromodomain helicase DNA binding protein 7
CHD9 chromodomain helicase DNA binding protein 9
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
CLDN17 claudin 17
CLEC1A C-type lectin domain family 1, member A
CLEC5A C-type lectin domain family 5, member A
CLUH clustered mitochondria (cluA/CLU1) homolog
CMKLR1 chemerin chemokine-like receptor 1
CMYA5 cardiomyopathy associated 5
CNRIP1 cannabinoid receptor interacting protein 1
CNTNAP2 contactin associated protein-like 2
CNTNAP4 contactin associated protein-like 4
CNTNAP5 contactin associated protein-like 5
COL12A1 collagen, type XII, alpha 1
COL9A2 collagen, type IX, alpha 2
CPNE4 copine IV
CREBBP CREB binding protein
CRISPLD1 cysteine-rich secretory protein LCCL domain containing 1
CSMD3 CUB and Sushi multiple domains 3
CSNK1A1 casein kinase 1, alpha 1
CTAGE1 cutaneous T-cell lymphoma-associated antigen 1
CTNND2 catenin (cadherin-associated protein), delta 2
CUL3 cullin 3
CXCL16 chemokine (C-X-C motif) ligand 16
CYP2A13 cytochrome P450, family 2, subfamily A, polypeptide 13
CYP2F1 cytochrome P450, family 2, subfamily F, polypeptide 1
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8
CYP4Z1 cytochrome P450, family 4, subfamily Z, polypeptide 1
DARS aspartyl-tRNA synthetase
DAZAP1 DAZ associated protein 1
DAZL deleted in azoospermia-like
DCAF4L2 DDB1 and CUL4 associated factor 4-like 2
DCC DCC netrin 1 receptor
DDR2 discoidin domain receptor tyrosine kinase 2
DDX60L DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like
DENND1C DENN/MADD domain containing 1C
DNA2 DNA replication helicase/nuclease 2
DNAH3 dynein, axonemal, heavy chain 3
DNAH6 dynein, axonemal, heavy chain 6
DNAH8 dynein, axonemal, heavy chain 8
DNASE2B deoxyribonuclease II beta
DPH2 DPH2 homolog (S. cerevisiae)
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3
DPP6 dipeptidyl-peptidase 6
DPYS dihydropyrimidinase
DQX1 DEAQ box RNA-dependent ATPase 1
DSG1 desmoglein 1
DSP desmoplakin
DTHD1 death domain containing 1
EDEM3 ER degradation enhancer, mannosidase alpha-like 3
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EFR3A EFR3 homolog A (S. cerevisiae)
EFTUD1 elongation factor Tu GTP binding domain containing 1
EGFR epidermal growth factor receptor
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2
EMB embigin
ENO3 enolase 3 (beta, muscle)
ENOX1 ecto-NOX disulfide-thiol exchanger 1
EP400 E1A binding protein p400
EPHA3 EPH receptor A3
ERV3-1 endogenous retrovirus group 3, member 1
ESRP1 epithelial splicing regulatory protein 1
EVI5L ecotropic viral integration site 5-like
F2 coagulation factor II (thrombin)
FAF1 Fas (TNFRSF6) associated factor 1
FAM111B family with sequence similarity 111, member B
FAM135B family with sequence similarity 135, member B
FAM13A family with sequence similarity 13, member A
FAM83H family with sequence similarity 83, member H
FANCD2 Fanconi anemia, complementation group D2
FBXO31 F-box protein 31
FBXW4 F-box and WD repeat domain containing 4
FCAMR Fc receptor, IgA, IgM, high affinity
FCGBP Fc fragment of IgG binding protein
FDPS farnesyl diphosphate synthase
FILIP1L filamin A interacting protein 1-like
FLNC filamin C, gamma
FMO6P flavin containing monooxygenase 6 pseudogene
FN1 fibronectin 1
FOCAD focadhesin
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FOSL2 FOS-like antigen 2
FOXG1 forkhead box G1
FRZB frizzled-related protein
FSIP2 fibrous sheath interacting protein 2
FUK fucokinase
GABRR3 gamma-aminobutyric acid (GABA) A receptor, rho 3 (gene/pseudogene)
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GIMAP6 GTPase, IMAP family member 6
GIMAP8 GTPase, IMAP family member 8
GK5 glycerol kinase 5 (putative)
GLDC glycine dehydrogenase (decarboxylating)
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GPATCH1 G patch domain containing 1
GREB1 growth regulation by estrogen in breast cancer 1
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GUCY2D guanylate cyclase 2D, membrane (retina-specific)
HABP2 hyaluronan binding protein 2
HAT1 histone acetyltransferase 1
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1
HDC histidine decarboxylase
HELT helt bHLH transcription factor
HEPHL1 hephaestin-like 1
HHATL hedgehog acyltransferase-like
HIBADH 3-hydroxyisobutyrate dehydrogenase
HIST1H2BL histone cluster 1, H2bl
HIST2H3PS2 histone cluster 2, H3, pseudogene 2
HLA-C major histocompatibility complex, class I, C
HOXD12 homeobox D12
HSH2D hematopoietic SH2 domain containing
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPG2 heparan sulfate proteoglycan 2
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
HYDIN HYDIN, axonemal central pair apparatus protein
IDO2 indoleamine 2,3-dioxygenase 2
IGSF3 immunoglobulin superfamily, member 3
IMPAD1 inositol monophosphatase domain containing 1
INVS inversin
IPO11 importin 11
IQGAP2 IQ motif containing GTPase activating protein 2
IQGAP3 IQ motif containing GTPase activating protein 3
IRAK2 interleukin-1 receptor-associated kinase 2
IRAK3 interleukin-1 receptor-associated kinase 3
IRS1 insulin receptor substrate 1
ITGB1BP1 integrin beta 1 binding protein 1
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITLN2 intelectin 2
KATNAL1 katanin p60 subunit A-like 1
KBTBD6 kelch repeat and BTB (POZ) domain containing 6
KDM8 lysine (K)-specific demethylase 8
KEL Kell blood group, metallo-endopeptidase
KIAA1109 KIAA1109
KIAA1671 KIAA1671
KIF5A kinesin family member 5A
KIR3DL3 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3
KMT2C lysine (K)-specific methyltransferase 2C
KMT2D lysine (K)-specific methyltransferase 2D
KRBA1 KRAB-A domain containing 1
KRT23 keratin 23, type I
KRT3 keratin 3, type II
L3MBTL3 l(3)mbt-like 3 (Drosophila)
LAMC1 laminin, gamma 1 (formerly LAMB2)
LARS leucyl-tRNA synthetase
LCE2B late cornified envelope 2B
LHCGR luteinizing hormone/choriogonadotropin receptor
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LIN37 lin-37 DREAM MuvB core complex component
LINGO2 leucine rich repeat and Ig domain containing 2
LPXN leupaxin
LRP1B low density lipoprotein receptor-related protein 1B
LRRIQ1 leucine-rich repeats and IQ motif containing 1
LRRN3 leucine rich repeat neuronal 3
LZTS2 leucine zipper, putative tumor suppressor 2
MAMLD1 mastermind-like domain containing 1
MAN1A1 mannosidase, alpha, class 1A, member 1
MBD5 methyl-CpG binding domain protein 5
MDFIC MyoD family inhibitor domain containing
MDM4 MDM4, p53 regulator
METTL2A methyltransferase like 2A
MFAP5 microfibrillar associated protein 5
MFN1 mitofusin 1
MIA3 melanoma inhibitory activity family, member 3
MKS1 Meckel syndrome, type 1
MND1 meiotic nuclear divisions 1 homolog (S. cerevisiae)
MOCS1 molybdenum cofactor synthesis 1
MPZL3 myelin protein zero-like 3
MRPL38 mitochondrial ribosomal protein L38
MRPL44 mitochondrial ribosomal protein L44
MRPS35 mitochondrial ribosomal protein S35
MUC17 mucin 17, cell surface associated
MUC4 mucin 4, cell surface associated
MYH15 myosin, heavy chain 15
MYH8 myosin, heavy chain 8, skeletal muscle, perinatal
MYLIP myosin regulatory light chain interacting protein
MYO3A myosin IIIA
NCAM1 neural cell adhesion molecule 1
NCOR1 nuclear receptor corepressor 1
NCOR2 nuclear receptor corepressor 2
NEU2 sialidase 2 (cytosolic sialidase)
NID2 nidogen 2 (osteonidogen)
NLRP4 NLR family, pyrin domain containing 4
NOBOX NOBOX oogenesis homeobox
NOL8 nucleolar protein 8
NOLC1 nucleolar and coiled-body phosphoprotein 1
NOP14 NOP14 nucleolar protein
NOS3 nitric oxide synthase 3 (endothelial cell)
NPEPPS aminopeptidase puromycin sensitive
NRG3 neuregulin 3
NSA2 NSA2 ribosome biogenesis homolog (S. cerevisiae)
NSUN7 NOP2/Sun domain family, member 7
NT5C1B 5'-nucleotidase, cytosolic IB
NTM neurotrimin
NUP160 nucleoporin 160kDa
OR10H3 olfactory receptor, family 10, subfamily H, member 3
OR10S1 olfactory receptor, family 10, subfamily S, member 1
OR10V1 olfactory receptor, family 10, subfamily V, member 1
OR14K1 olfactory receptor, family 14, subfamily K, member 1
OR1S2 olfactory receptor, family 1, subfamily S, member 2
OR2L3 olfactory receptor, family 2, subfamily L, member 3
OR2T2 olfactory receptor, family 2, subfamily T, member 2
OR2T4 olfactory receptor, family 2, subfamily T, member 4
OR4A47 olfactory receptor, family 4, subfamily A, member 47
OR4C6 olfactory receptor, family 4, subfamily C, member 6
OR5C1 olfactory receptor, family 5, subfamily C, member 1
OR5D16 olfactory receptor, family 5, subfamily D, member 16
OR8H3 olfactory receptor, family 8, subfamily H, member 3
OSBPL3 oxysterol binding protein-like 3
P2RY11 purinergic receptor P2Y, G-protein coupled, 11
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PARP12 poly (ADP-ribose) polymerase family, member 12
PARP15 poly (ADP-ribose) polymerase family, member 15
PCBP4 poly(rC) binding protein 4
PCDH12 protocadherin 12
PCDH17 protocadherin 17
PCDHGC3 protocadherin gamma subfamily C, 3
PCF11 PCF11 cleavage and polyadenylation factor subunit
PDXDC2P pyridoxal-dependent decarboxylase domain containing 2, pseudogene
PEG3 paternally expressed 3
PHEX phosphate regulating endopeptidase homolog, X-linked
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PKD1L1 polycystic kidney disease 1 like 1
PKD1L2 polycystic kidney disease 1-like 2 (gene/pseudogene)
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1
PKN1 protein kinase N1
PLCXD3 phosphatidylinositol-specific phospholipase C, X domain containing 3
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
PLS1 plastin 1
PLXND1 plexin D1
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
PMVK phosphomevalonate kinase
POLE polymerase (DNA directed), epsilon, catalytic subunit
POLR3A polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
PPAN-P2RY11 PPAN-P2RY11 readthrough
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4
PRAME preferentially expressed antigen in melanoma
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
PRKCG protein kinase C, gamma
PRMT8 protein arginine methyltransferase 8
PRODH proline dehydrogenase (oxidase) 1
PRR23C proline rich 23C
PRSS38 protease, serine, 38
PRUNE2 prune homolog 2 (Drosophila)
PRX periaxin
PSG5 pregnancy specific beta-1-glycoprotein 5
PSMG1 proteasome (prosome, macropain) assembly chaperone 1
PTCH2 patched 2
PZP pregnancy-zone protein
RANBP2 RAN binding protein 2
RANBP6 RAN binding protein 6
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RBBP4 retinoblastoma binding protein 4
RBKS ribokinase
RECQL4 RecQ protein-like 4
REV1 REV1, polymerase (DNA directed)
RFPL1 ret finger protein-like 1
RHOT1 ras homolog family member T1
RHPN2 rhophilin, Rho GTPase binding protein 2
RIMS2 regulating synaptic membrane exocytosis 2
RLTPR RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RPAP1 RNA polymerase II associated protein 1
RPAP2 RNA polymerase II associated protein 2
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
RTN3 reticulon 3
RTTN rotatin
RUFY3 RUN and FYVE domain containing 3
RYR2 ryanodine receptor 2 (cardiac)
S100A7L2 S100 calcium binding protein A7-like 2
SAMD9L sterile alpha motif domain containing 9-like
SAMHD1 SAM domain and HD domain 1
SASH1 SAM and SH3 domain containing 1
SCUBE1 signal peptide, CUB domain, EGF-like 1
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SH3BP5 SH3-domain binding protein 5 (BTK-associated)
SHD Src homology 2 domain containing transforming protein D
SHKBP1 SH3KBP1 binding protein 1
SIDT2 SID1 transmembrane family, member 2
SIPA1L1 signal-induced proliferation-associated 1 like 1
SLC22A14 solute carrier family 22, member 14
SLC2A12 solute carrier family 2 (facilitated glucose transporter), member 12
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC35B3 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3
SLC45A4 solute carrier family 45, member 4
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SLFN12L schlafen family member 12-like
SLITRK2 SLIT and NTRK-like family, member 2
SNX3 sorting nexin 3
SOSTDC1 sclerostin domain containing 1
SPAG11A sperm associated antigen 11A
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
SPPL2A signal peptide peptidase like 2A
SPTA1 spectrin, alpha, erythrocytic 1
SRRM2 serine/arginine repetitive matrix 2
SRSF12 serine/arginine-rich splicing factor 12
SSU72 SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae)
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
STAT4 signal transducer and activator of transcription 4
SVIL supervillin
SVOPL SVOP-like
SYNE1 spectrin repeat containing, nuclear envelope 1
SYNE2 spectrin repeat containing, nuclear envelope 2
TACC2 transforming, acidic coiled-coil containing protein 2
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TAS1R2 taste receptor, type 1, member 2
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
TBC1D15 TBC1 domain family, member 15
TEK TEK tyrosine kinase, endothelial
TEX2 testis expressed 2
THEG theg spermatid protein
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1
TJP1 tight junction protein 1
TMEM132B transmembrane protein 132B
TMEM200C transmembrane protein 200C
TNXB tenascin XB
TP53 tumor protein p53
TP73 tumor protein p73
TPM4 tropomyosin 4
TPTE transmembrane phosphatase with tensin homology
TRIM42 tripartite motif containing 42
TRIM64B tripartite motif containing 64B
TRIML2 tripartite motif family-like 2
TRIOBP TRIO and F-actin binding protein
TRPC6 transient receptor potential cation channel, subfamily C, member 6
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TRPM5 transient receptor potential cation channel, subfamily M, member 5
TRPV5 transient receptor potential cation channel, subfamily V, member 5
TSPAN8 tetraspanin 8
TTC21B tetratricopeptide repeat domain 21B
TUBG1 tubulin, gamma 1
TXK TXK tyrosine kinase
TYK2 tyrosine kinase 2
UBAP2 ubiquitin associated protein 2
UBR1 ubiquitin protein ligase E3 component n-recognin 1
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17
UMOD uromodulin
UNC80 unc-80 homolog (C. elegans)
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast)
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast)
USH2A Usher syndrome 2A (autosomal recessive, mild)
VAV1 vav 1 guanine nucleotide exchange factor
VCAN versican
VEGFC vascular endothelial growth factor C
VPS13B vacuolar protein sorting 13 homolog B (yeast)
VWA5B2 von Willebrand factor A domain containing 5B2
WDR74 WD repeat domain 74
WDR87 WD repeat domain 87
WNK1 WNK lysine deficient protein kinase 1
WNT5B wingless-type MMTV integration site family, member 5B
WWOX WW domain containing oxidoreductase
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRRA1 X-ray radiation resistance associated 1
ZC3H12A zinc finger CCCH-type containing 12A
ZC3H7A zinc finger CCCH-type containing 7A
ZIM2 zinc finger, imprinted 2
ZKSCAN8 zinc finger with KRAB and SCAN domains 8
ZMYM6 zinc finger, MYM-type 6
ZNF132 zinc finger protein 132
ZNF180 zinc finger protein 180
ZNF239 zinc finger protein 239
ZNF24 zinc finger protein 24
ZNF285 zinc finger protein 285
ZNF44 zinc finger protein 44
ZNF449 zinc finger protein 449
ZNF518A zinc finger protein 518A
ZNF560 zinc finger protein 560
ZNF587 zinc finger protein 587
ZNF611 zinc finger protein 611
ZNF658 zinc finger protein 658
ZNF711 zinc finger protein 711
ZNF729 zinc finger protein 729
ZNF841 zinc finger protein 841
ZSCAN12 zinc finger and SCAN domain containing 12