NCI-H520 Gene Set

Dataset COSMIC Cell Line Gene CNV Profiles
Category genomics
Type cell line
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Genes

85 genes with high or low copy number in NCI-H520 relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.

high copy number

Symbol Name Standardized Value
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3 4.51153
HPDL 4-hydroxyphenylpyruvate dioxygenase-like 4.51153
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa 4.51153
MUTYH mutY homolog 4.51153
ZSWIM5 zinc finger, SWIM-type containing 5 4.51153
NAP1L5 nucleosome assembly protein 1-like 5 4.51153
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) 4.51153
TESK2 testis-specific kinase 2 4.51153
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria 4.51153
TOE1 target of EGR1, member 1 (nuclear) 4.51153
UROD uroporphyrinogen decarboxylase 4.51153
PRDX1 peroxiredoxin 1 4.51153
FAM13A-AS1 FAM13A antisense RNA 1 4.51153
CCDC163P coiled-coil domain containing 163, pseudogene 4.51153
PTCH2 patched 2 4.51153
NPFFR2 neuropeptide FF receptor 2 2.93899
WDR3 WD repeat domain 3 2.59653
GDAP2 ganglioside induced differentiation associated protein 2 2.59653
RRAGC Ras-related GTP binding C 2.59653
NDUFS5 NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) 2.59653
SPAG17 sperm associated antigen 17 2.59653
GJA9 gap junction protein, alpha 9, 59kDa 2.59653
MYCBP MYC binding protein 2.59653
RHBDL2 rhomboid, veinlet-like 2 (Drosophila) 2.49065
GJA9-MYCBP GJA9-MYCBP readthrough 2.49065
AKIRIN1 akirin 1 2.49065
HTR3D 5-hydroxytryptamine (serotonin) receptor 3D, ionotropic 2.39327
ABCC5-AS1 ABCC5 antisense RNA 1 2.39327
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 2.39327
KIAA0754 KIAA0754 2.39327
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa 2.36889
CAMK2N2 calcium/calmodulin-dependent protein kinase II inhibitor 2 2.36889
VWA5B2 von Willebrand factor A domain containing 5B2 2.36889
AP2M1 adaptor-related protein complex 2, mu 1 subunit 2.36889
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 2.36889
DVL3 dishevelled segment polarity protein 3 2.36889
HTR3C 5-hydroxytryptamine (serotonin) receptor 3C, ionotropic 2.36889
ECE2 endothelin converting enzyme 2 2.36889
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 2.36889
HTR3E 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic 2.36889
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 2.36889
MIR1224 microRNA 1224 2.36889
ALG3 ALG3, alpha-1,3- mannosyltransferase 2.36889
ZFP69B ZFP69 zinc finger protein B 2.35236
SNORA55 small nucleolar RNA, H/ACA box 55 2.35236
ZFP69 ZFP69 zinc finger protein 2.35236
PPIEL peptidylprolyl isomerase E-like pseudogene 2.35236
ZNF684 zinc finger protein 684 2.35236
MACF1 microtubule-actin crosslinking factor 1 2.35236
EXO5 exonuclease 5 2.35236
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) 2.35236
MIR599 microRNA 599 2.3178
SMAP2 small ArfGAP2 2.3178
MIR875 microRNA 875 2.3178
COL9A2 collagen, type IX, alpha 2 2.3178
HEYL hes-related family bHLH transcription factor with YRPW motif-like 2.3178
PPT1 palmitoyl-protein thioesterase 1 2.30944
NT5C1A 5'-nucleotidase, cytosolic IA 2.30944
BMP8A bone morphogenetic protein 8a 2.30944
ZMPSTE24 zinc metallopeptidase STE24 2.30944
TMCO2 transmembrane and coiled-coil domains 2 2.30944
RLF rearranged L-myc fusion 2.283
HPCAL4 hippocalcin like 4 2.283
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 2.283
VPS13B vacuolar protein sorting 13 homolog B (yeast) 2.283
MFSD2A major facilitator superfamily domain containing 2A 2.25904
OXCT2 3-oxoacid CoA transferase 2 2.24845
PPIE peptidylprolyl isomerase E (cyclophilin E) 2.24845
BMP8B bone morphogenetic protein 8b 2.24845
TRIT1 tRNA isopentenyltransferase 1 2.24139
TMED11P transmembrane emp24 protein transport domain containing 11, pseudogene 2.15316
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3 2.15316
SPON2 spondin 2, extracellular matrix protein 2.15316
IDUA iduronidase, alpha-L- 2.15316
FGFRL1 fibroblast growth factor receptor-like 1 2.15316
SLC26A1 solute carrier family 26 (anion exchanger), member 1 2.15316
RNF212 ring finger protein 212 2.15316
FAM13A family with sequence similarity 13, member A 2.15316
FAM46C family with sequence similarity 46, member C 2.10038

low copy number

Symbol Name Standardized Value
PRAMEF2 PRAME family member 2 -3.83684
AKAP13 A kinase (PRKA) anchor protein 13 -3.24687
CTAGE5 CTAGE family, member 5 -3.18666
FBXO33 F-box protein 33 -3.18666
OR52N5 olfactory receptor, family 52, subfamily N, member 5 -2.84224
OR52N1 olfactory receptor, family 52, subfamily N, member 1 -2.73524