NCI-H460 Gene Set

Dataset Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles
Category genomics
Type cell line
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Genes

176 genes mutated in the NCI-H460 cell line from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles dataset.

Symbol Name
AASDH aminoadipate-semialdehyde dehydrogenase
ABLIM2 actin binding LIM protein family, member 2
ACAT2 acetyl-CoA acetyltransferase 2
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
AKR1C3 aldo-keto reductase family 1, member C3
AKR1C4 aldo-keto reductase family 1, member C4
ALMS1 Alstrom syndrome protein 1
ALOXE3 arachidonate lipoxygenase 3
ANGEL1 angel homolog 1 (Drosophila)
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1
ATAD3B ATPase family, AAA domain containing 3B
BRWD1 bromodomain and WD repeat domain containing 1
C16ORF62 chromosome 16 open reading frame 62
CALD1 caldesmon 1
CASZ1 castor zinc finger 1
CCDC68 coiled-coil domain containing 68
CCP110 centriolar coiled coil protein 110kDa
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CD164 CD164 molecule, sialomucin
CD53 CD53 molecule
CD83 CD83 molecule
CEP170B centrosomal protein 170B
CLIP3 CAP-GLY domain containing linker protein 3
COMP cartilage oligomeric matrix protein
COQ10A coenzyme Q10 homolog A (S. cerevisiae)
CTSA cathepsin A
CUL3 cullin 3
CYB5R4 cytochrome b5 reductase 4
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila)
DNAH17 dynein, axonemal, heavy chain 17
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13
DOC2A double C2-like domains, alpha
DOPEY1 dopey family member 1
DUS2 dihydrouridine synthase 2
EGR3 early growth response 3
EIF3A eukaryotic translation initiation factor 3, subunit A
ENTHD2 ENTH domain containing 2
EXOC2 exocyst complex component 2
EXOC3 exocyst complex component 3
FLYWCH1 FLYWCH-type zinc finger 1
FRAT2 frequently rearranged in advanced T-cell lymphomas 2
FSTL4 follistatin-like 4
FYN FYN proto-oncogene, Src family tyrosine kinase
GALNT13 polypeptide N-acetylgalactosaminyltransferase 13
GAS2L3 growth arrest-specific 2 like 3
GLB1L galactosidase, beta 1-like
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GOLGA5 golgin A5
GOLGB1 golgin B1
GPCPD1 glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HEG1 heart development protein with EGF-like domains 1
HID1 HID1 domain containing
IGFBP1 insulin-like growth factor binding protein 1
IRF4 interferon regulatory factor 4
ITPKC inositol-trisphosphate 3-kinase C
JAG1 jagged 1
KAT8 K(lysine) acetyltransferase 8
KEAP1 kelch-like ECH-associated protein 1
KIAA0825 KIAA0825
KIF14 kinesin family member 14
KIF15 kinesin family member 15
KIF4B kinesin family member 4B
KIF7 kinesin family member 7
KLHL36 kelch-like family member 36
KRAS Kirsten rat sarcoma viral oncogene homolog
LAMA5 laminin, alpha 5
LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
LAT2 linker for activation of T cells family, member 2
LIFR leukemia inhibitory factor receptor alpha
LNPEP leucyl/cystinyl aminopeptidase
LRBA LPS-responsive vesicle trafficking, beach and anchor containing
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRRC16B leucine rich repeat containing 16B
LRRC24 leucine rich repeat containing 24
LYST lysosomal trafficking regulator
MAN2C1 mannosidase, alpha, class 2C, member 1
MAP2K1 mitogen-activated protein kinase kinase 1
MARC2 mitochondrial amidoxime reducing component 2
METTL5 methyltransferase like 5
MGA MGA, MAX dimerization protein
MMS22L MMS22-like, DNA repair protein
MON2 MON2 homolog (S. cerevisiae)
MROH1 maestro heat-like repeat family member 1
MRPL3 mitochondrial ribosomal protein L3
MYL9 myosin, light chain 9, regulatory
MYO5C myosin VC
NAT6 N-acetyltransferase 6 (GCN5-related)
NBN nibrin
NCOA6 nuclear receptor coactivator 6
NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa
NELFCD negative elongation factor complex member C/D
NIN ninein (GSK3B interacting protein)
NIPBL Nipped-B homolog (Drosophila)
NOP2 NOP2 nucleolar protein
NOTCH3 notch 3
NTSR1 neurotensin receptor 1 (high affinity)
NUP210 nucleoporin 210kDa
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
PAPOLB poly(A) polymerase beta (testis specific)
PARN poly(A)-specific ribonuclease
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PIGW phosphatidylinositol glycan anchor biosynthesis, class W
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLEC plectin
PLEK2 pleckstrin 2
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PRRC2C proline-rich coiled-coil 2C
PTK2 protein tyrosine kinase 2
PYHIN1 pyrin and HIN domain family, member 1
RAD21 RAD21 homolog (S. pombe)
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RPTOR regulatory associated protein of MTOR, complex 1
SATB1 SATB homeobox 1
SCAF4 SR-related CTD-associated factor 4
SDK1 sidekick cell adhesion molecule 1
SETD5 SET domain containing 5
SGMS2 sphingomyelin synthase 2
SH2B2 SH2B adaptor protein 2
SH3PXD2B SH3 and PX domains 2B
SHANK2 SH3 and multiple ankyrin repeat domains 2
SLC35B2 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2
SLC35E2 solute carrier family 35, member E2
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SPRY4 sprouty homolog 4 (Drosophila)
SRRM2 serine/arginine repetitive matrix 2
STAT2 signal transducer and activator of transcription 2, 113kDa
STK11 serine/threonine kinase 11
SUGP2 SURP and G patch domain containing 2
SYDE2 synapse defective 1, Rho GTPase, homolog 2 (C. elegans)
TAF1L TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like
TARBP1 TAR (HIV-1) RNA binding protein 1
TCF7 transcription factor 7 (T-cell specific, HMG-box)
TET3 tet methylcytosine dioxygenase 3
THRA thyroid hormone receptor, alpha
TMEM178B transmembrane protein 178B
TMEM33 transmembrane protein 33
TMEM57 transmembrane protein 57
TMX3 thioredoxin-related transmembrane protein 3
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNRC18 trinucleotide repeat containing 18
TRIM13 tripartite motif containing 13
TRIM22 tripartite motif containing 22
TRIM62 tripartite motif containing 62
TRPA1 transient receptor potential cation channel, subfamily A, member 1
TRPM7 transient receptor potential cation channel, subfamily M, member 7
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1
UHRF1BP1L UHRF1 binding protein 1-like
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
UTRN utrophin
WDR44 WD repeat domain 44
WISP2 WNT1 inducible signaling pathway protein 2
WNK2 WNK lysine deficient protein kinase 2
WNT5B wingless-type MMTV integration site family, member 5B
ZBTB26 zinc finger and BTB domain containing 26
ZFHX3 zinc finger homeobox 3
ZFP64 ZFP64 zinc finger protein
ZNF341 zinc finger protein 341
ZNF438 zinc finger protein 438
ZNF467 zinc finger protein 467
ZNF628 zinc finger protein 628
ZNF638 zinc finger protein 638
ZNF652 zinc finger protein 652
ZNF773 zinc finger protein 773
ZNF774 zinc finger protein 774
ZNF784 zinc finger protein 784
ZNF850 zinc finger protein 850
ZRANB3 zinc finger, RAN-binding domain containing 3
ZSCAN25 zinc finger and SCAN domain containing 25