NCI-H441 Gene Set

Dataset Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles
Category genomics
Type cell line
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Genes

165 genes mutated in the NCI-H441 cell line from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles dataset.

Symbol Name
ADAL adenosine deaminase-like
ADNP activity-dependent neuroprotector homeobox
AFF1 AF4/FMR2 family, member 1
AHNAK2 AHNAK nucleoprotein 2
AKIRIN1 akirin 1
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit
ALG14 ALG14, UDP-N-acetylglucosaminyltransferase subunit
ALG2 ALG2, alpha-1,3/1,6-mannosyltransferase
ALPI alkaline phosphatase, intestinal
ANKHD1 ankyrin repeat and KH domain containing 1
ANKHD1-EIF4EBP3 ANKHD1-EIF4EBP3 readthrough
ANKIB1 ankyrin repeat and IBR domain containing 1
ANKRD17 ankyrin repeat domain 17
ANKRD50 ankyrin repeat domain 50
AREG amphiregulin
ARHGAP39 Rho GTPase activating protein 39
ARHGAP8 Rho GTPase activating protein 8
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARMC10 armadillo repeat containing 10
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ASS1 argininosuccinate synthase 1
ASXL2 additional sex combs like transcriptional regulator 2
ATP11A ATPase, class VI, type 11A
BIVM-ERCC5 BIVM-ERCC5 readthrough
BRPF3 bromodomain and PHD finger containing, 3
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C11ORF95 chromosome 11 open reading frame 95
C1ORF131 chromosome 1 open reading frame 131
C5ORF42 chromosome 5 open reading frame 42
C6ORF226 chromosome 6 open reading frame 226
C9ORF69 chromosome 9 open reading frame 69
CACTIN cactin, spliceosome C complex subunit
CATSPER1 cation channel, sperm associated 1
CBX2 chromobox homolog 2
CCDC22 coiled-coil domain containing 22
CCDC88C coiled-coil domain containing 88C
CCHCR1 coiled-coil alpha-helical rod protein 1
CCNY cyclin Y
CD37 CD37 molecule
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase
CDK13 cyclin-dependent kinase 13
CFAP44 cilia and flagella associated protein 44
CHD1 chromodomain helicase DNA binding protein 1
CLCN6 chloride channel, voltage-sensitive 6
COG8 component of oligomeric golgi complex 8
CROT carnitine O-octanoyltransferase
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
DDX19A DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A
DHX30 DEAH (Asp-Glu-Ala-His) box helicase 30
DPH2 DPH2 homolog (S. cerevisiae)
DPY19L4 dpy-19-like 4 (C. elegans)
DROSHA drosha, ribonuclease type III
EAF1 ELL associated factor 1
ELAC2 elaC ribonuclease Z 2
EP300 E1A binding protein p300
ERCC5 excision repair cross-complementation group 5
F11R F11 receptor
FAM13A family with sequence similarity 13, member A
FAM193B family with sequence similarity 193, member B
FBXO18 F-box protein, helicase, 18
FBXO7 F-box protein 7
FLII flightless I homolog (Drosophila)
FNIP2 folliculin interacting protein 2
FUCA1 fucosidase, alpha-L- 1, tissue
FZD1 frizzled class receptor 1
GALNT5 polypeptide N-acetylgalactosaminyltransferase 5
GBA2 glucosidase, beta (bile acid) 2
GJC3 gap junction protein, gamma 3, 30.2kDa
GLE1 GLE1 RNA export mediator
GLG1 golgi glycoprotein 1
GON4L gon-4-like (C. elegans)
GSTZ1 glutathione S-transferase zeta 1
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa
HDAC9 histone deacetylase 9
HEATR5A HEAT repeat containing 5A
HEATR5B HEAT repeat containing 5B
HTT huntingtin
INTS1 integrator complex subunit 1
IQGAP1 IQ motif containing GTPase activating protein 1
ITGB4 integrin, beta 4
ITSN1 intersectin 1 (SH3 domain protein)
JMY junction mediating and regulatory protein, p53 cofactor
KIAA1109 KIAA1109
KIF18B kinesin family member 18B
KIF4B kinesin family member 4B
KPNA7 karyopherin alpha 7 (importin alpha 8)
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT75 keratin 75, type II
MAP9 microtubule-associated protein 9
MAPK7 mitogen-activated protein kinase 7
MID2 midline 2
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MUC21 mucin 21, cell surface associated
MUC4 mucin 4, cell surface associated
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase
MYO7A myosin VIIA
MYRF myelin regulatory factor
NAV2 neuron navigator 2
NDE1 nudE neurodevelopment protein 1
NDUFV3 NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2
NUP210 nucleoporin 210kDa
NUP62 nucleoporin 62kDa
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
PAPOLA poly(A) polymerase alpha
PARPBP PARP1 binding protein
PATL1 protein associated with topoisomerase II homolog 1 (yeast)
PCNXL2 pecanex-like 2 (Drosophila)
PGBD2 piggyBac transposable element derived 2
PGD phosphogluconate dehydrogenase
PHOSPHO2 phosphatase, orphan 2
PPL periplakin
PPP1R3F protein phosphatase 1, regulatory subunit 3F
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRPF31 pre-mRNA processing factor 31
PRR5-ARHGAP8 PRR5-ARHGAP8 readthrough
PRSS23 protease, serine, 23
PUSL1 pseudouridylate synthase-like 1
PYGB phosphorylase, glycogen; brain
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RFWD3 ring finger and WD repeat domain 3
RNGTT RNA guanylyltransferase and 5'-phosphatase
RPGR retinitis pigmentosa GTPase regulator
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SHROOM1 shroom family member 1
SKI SKI proto-oncogene
SKIV2L2 superkiller viralicidic activity 2-like 2 (S. cerevisiae)
SLC22A31 solute carrier family 22, member 31
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32
SLFN5 schlafen family member 5
SMC4 structural maintenance of chromosomes 4
SP110 SP110 nuclear body protein
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome)
ST5 suppression of tumorigenicity 5
SUGP2 SURP and G patch domain containing 2
SYMPK symplekin
SYTL1 synaptotagmin-like 1
SZT2 seizure threshold 2 homolog (mouse)
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
THBS3 thrombospondin 3
TIGD1 tigger transposable element derived 1
TLN2 talin 2
TMEM14C transmembrane protein 14C
TMEM237 transmembrane protein 237
TMEM241 transmembrane protein 241
TNC tenascin C
TNRC6B trinucleotide repeat containing 6B
TP53 tumor protein p53
TRAK1 trafficking protein, kinesin binding 1
TRRAP transformation/transcription domain-associated protein
TTF2 transcription termination factor, RNA polymerase II
TYK2 tyrosine kinase 2
UBE4B ubiquitination factor E4B
UNC13D unc-13 homolog D (C. elegans)
USP36 ubiquitin specific peptidase 36
WSB1 WD repeat and SOCS box containing 1
XPC xeroderma pigmentosum, complementation group C
ZBTB37 zinc finger and BTB domain containing 37
ZMYND8 zinc finger, MYND-type containing 8
ZNF329 zinc finger protein 329