NCI-H441 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
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Genes

314 genes with high or low expression in NCI-H441 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase 3.17445
CCNJL cyclin J-like 3.1424
FAM89B family with sequence similarity 89, member B 2.75471
WSB1 WD repeat and SOCS box containing 1 2.73093
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3 2.61446
CPD carboxypeptidase D 2.49688
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 2.48887
ADGRF1 adhesion G protein-coupled receptor F1 2.48081
TMEM53 transmembrane protein 53 2.4218
WARS tryptophanyl-tRNA synthetase 2.354
TRAF4 TNF receptor-associated factor 4 2.33149
CYB5A cytochrome b5 type A (microsomal) 2.32049
SFTPB surfactant protein B 2.29416
RAB1A RAB1A, member RAS oncogene family 2.26854
HOXD1 homeobox D1 2.21046
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 2.17645
PLAC1 placenta-specific 1 2.17593
SPTB spectrin, beta, erythrocytic 2.17475
LPP LIM domain containing preferred translocation partner in lipoma 2.15316
STK16 serine/threonine kinase 16 2.13748
SRPX2 sushi-repeat containing protein, X-linked 2 2.13074
FLOT2 flotillin 2 2.12087
ZNF212 zinc finger protein 212 2.09875
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 2.09268
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 2.07822
TMC5 transmembrane channel-like 5 2.06943
SERTAD2 SERTA domain containing 2 2.06317
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 2.05019
FSCN2 fascin actin-bundling protein 2, retinal 2.04361
MBD4 methyl-CpG binding domain protein 4 2.04216
GORASP2 golgi reassembly stacking protein 2, 55kDa 2.01697
KDR kinase insert domain receptor 2.00799
LTBP3 latent transforming growth factor beta binding protein 3 1.99786
KIAA0100 KIAA0100 1.99731
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase 1.99479
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1 1.9856
TREM1 triggering receptor expressed on myeloid cells 1 1.9841
TMEM156 transmembrane protein 156 1.97193
FUCA1 fucosidase, alpha-L- 1, tissue 1.94965
FUT2 fucosyltransferase 2 (secretor status included) 1.94366
ACAD8 acyl-CoA dehydrogenase family, member 8 1.93128
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11 1.93108
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae) 1.92174
MRPL49 mitochondrial ribosomal protein L49 1.92119
KIAA0319L KIAA0319-like 1.90996
GAS8 growth arrest-specific 8 1.9011
FASTK Fas-activated serine/threonine kinase 1.89412
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic) 1.89159
EPHX3 epoxide hydrolase 3 1.88586
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1 1.8817
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 1.87616
WASL Wiskott-Aldrich syndrome-like 1.86699
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 1.86082
RALY RALY heterogeneous nuclear ribonucleoprotein 1.84051
AQP4 aquaporin 4 1.83006
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 1.82656
TXNRD3 thioredoxin reductase 3 1.82138
GFPT1 glutamine--fructose-6-phosphate transaminase 1 1.80311
ADGRF5 adhesion G protein-coupled receptor F5 1.80004
PPP1R12B protein phosphatase 1, regulatory subunit 12B 1.79595
EHBP1L1 EH domain binding protein 1-like 1 1.78236
TDRD1 tudor domain containing 1 1.7727
TOP1 topoisomerase (DNA) I 1.77253
IFT20 intraflagellar transport 20 1.77023
APRT adenine phosphoribosyltransferase 1.75981
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B 1.75267
ALCAM activated leukocyte cell adhesion molecule 1.75101
KLHL24 kelch-like family member 24 1.75007
HCG4B HLA complex group 4B (non-protein coding) 1.74576
CRYBB3 crystallin, beta B3 1.74347
ACP6 acid phosphatase 6, lysophosphatidic 1.73143
OAZ3 ornithine decarboxylase antizyme 3 1.72852
CSNK1A1 casein kinase 1, alpha 1 1.7164
BTC betacellulin 1.7149
MTMR3 myotubularin related protein 3 1.71248
DNM3 dynamin 3 1.70981
RPL23AP7 ribosomal protein L23a pseudogene 7 1.70722
MVP major vault protein 1.70524
GGNBP2 gametogenetin binding protein 2 1.69901
ZNF282 zinc finger protein 282 1.69865
DIDO1 death inducer-obliterator 1 1.69309
XYLT2 xylosyltransferase II 1.69157
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 1.68991
DLG3 discs, large homolog 3 (Drosophila) 1.68062
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.67099
LRP10 low density lipoprotein receptor-related protein 10 1.66773
NKX2-1 NK2 homeobox 1 1.66445
ZFAND3 zinc finger, AN1-type domain 3 1.65937
USP22 ubiquitin specific peptidase 22 1.64955
TOLLIP toll interacting protein 1.64424
MAPK13 mitogen-activated protein kinase 13 1.6391
NR1I3 nuclear receptor subfamily 1, group I, member 3 1.63652
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 1.62874
POLB polymerase (DNA directed), beta 1.6282
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.61375
GP1BB glycoprotein Ib (platelet), beta polypeptide 1.61279
FOXK2 forkhead box K2 1.61018
FBXO34 F-box protein 34 1.60649
PRSS8 protease, serine, 8 1.60015
SNX6 sorting nexin 6 1.59872
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 1.59609
ATP10A ATPase, class V, type 10A 1.59439
USP25 ubiquitin specific peptidase 25 1.59164
TRIM8 tripartite motif containing 8 1.57593
AKAP6 A kinase (PRKA) anchor protein 6 1.57544
IPP intracisternal A particle-promoted polypeptide 1.56712
CEP68 centrosomal protein 68kDa 1.56551
AGO1 argonaute RISC catalytic component 1 1.56
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 1.55817
LPCAT1 lysophosphatidylcholine acyltransferase 1 1.55578
AP1S1 adaptor-related protein complex 1, sigma 1 subunit 1.55254
DNAL4 dynein, axonemal, light chain 4 1.55075
RAB6A RAB6A, member RAS oncogene family 1.54944
ITGAV integrin, alpha V 1.54672
IL13RA1 interleukin 13 receptor, alpha 1 1.54395
PHC2 polyhomeotic homolog 2 (Drosophila) 1.53936
TMEM127 transmembrane protein 127 1.53852
C4BPB complement component 4 binding protein, beta 1.52096
TRADD TNFRSF1A-associated via death domain 1.51919
CHMP1A charged multivesicular body protein 1A 1.50985
MUC1 mucin 1, cell surface associated 1.50277
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 1.50272
GJD2 gap junction protein, delta 2, 36kDa 1.50241
CAMTA2 calmodulin binding transcription activator 2 1.50233
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F 1.50053
RAB2A RAB2A, member RAS oncogene family 1.4975
APLP2 amyloid beta (A4) precursor-like protein 2 1.49113
PPP1R9A protein phosphatase 1, regulatory subunit 9A 1.4906
DUSP6 dual specificity phosphatase 6 1.48728
PSAP prosaposin 1.4773
NOS3 nitric oxide synthase 3 (endothelial cell) 1.47539
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase) 1.47478
CASP6 caspase 6, apoptosis-related cysteine peptidase 1.46964
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) 1.45114
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) 1.44947
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 1.44847
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene 1.44823
EXPH5 exophilin 5 1.44698
LRP5 low density lipoprotein receptor-related protein 5 1.44641
CTBP2 C-terminal binding protein 2 1.44571
SIPA1 signal-induced proliferation-associated 1 1.44457
RSF1 remodeling and spacing factor 1 1.44441
SCNN1A sodium channel, non voltage gated 1 alpha subunit 1.43954
LRP6 low density lipoprotein receptor-related protein 6 1.43368
BRAF B-Raf proto-oncogene, serine/threonine kinase 1.43359
LYPLA1 lysophospholipase I 1.43025
FGL1 fibrinogen-like 1 1.42943
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 1.42866
PON1 paraoxonase 1 1.42521
SDC1 syndecan 1 1.4251
SHPK sedoheptulokinase 1.42173
MXI1 MAX interactor 1, dimerization protein 1.42116
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 1.42034
CLUAP1 clusterin associated protein 1 1.41798

low expression

Symbol Name Standardized Value
SCAF11 SR-related CTD-associated factor 11 -3.53725
TNRC6B trinucleotide repeat containing 6B -3.53716
TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast) -3.31066
FAM65A family with sequence similarity 65, member A -3.19473
PCNA proliferating cell nuclear antigen -3.15903
HAUS6 HAUS augmin-like complex, subunit 6 -2.94444
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 -2.93491
NAP1L2 nucleosome assembly protein 1-like 2 -2.89285
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 -2.87044
CNTN1 contactin 1 -2.60878
TWF1 twinfilin actin binding protein 1 -2.60562
TACC1 transforming, acidic coiled-coil containing protein 1 -2.60132
FASTKD5 FAST kinase domains 5 -2.60112
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 -2.55594
SETX senataxin -2.49465
IDH3B isocitrate dehydrogenase 3 (NAD+) beta -2.48842
DTNA dystrobrevin, alpha -2.41874
SIRPA signal-regulatory protein alpha -2.41499
CLCN5 chloride channel, voltage-sensitive 5 -2.3832
RFC3 replication factor C (activator 1) 3, 38kDa -2.33605
RPH3A rabphilin 3A -2.29568
PECR peroxisomal trans-2-enoyl-CoA reductase -2.26303
PANK3 pantothenate kinase 3 -2.22375
SYNC syncoilin, intermediate filament protein -2.15137
NDUFA13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 -2.10371
PDHX pyruvate dehydrogenase complex, component X -2.08619
CSF1 colony stimulating factor 1 (macrophage) -2.06371
HINT1 histidine triad nucleotide binding protein 1 -2.06061
CLCC1 chloride channel CLIC-like 1 -2.02483
DR1 down-regulator of transcription 1, TBP-binding (negative cofactor 2) -2.01555
STXBP6 syntaxin binding protein 6 (amisyn) -1.9822
PRPF38B pre-mRNA processing factor 38B -1.97913
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta -1.9623
ZCCHC10 zinc finger, CCHC domain containing 10 -1.9585
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) -1.95468
RBM26 RNA binding motif protein 26 -1.94069
MMP16 matrix metallopeptidase 16 (membrane-inserted) -1.93401
COQ7 coenzyme Q7 homolog, ubiquinone (yeast) -1.93114
FGFR2 fibroblast growth factor receptor 2 -1.88619
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -1.86652
PEG3 paternally expressed 3 -1.86184
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6 -1.83634
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 -1.83333
CCNK cyclin K -1.83201
COL5A1 collagen, type V, alpha 1 -1.81871
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -1.80885
HCCS holocytochrome c synthase -1.80328
CENPN centromere protein N -1.80215
COL4A1 collagen, type IV, alpha 1 -1.79348
CKS2 CDC28 protein kinase regulatory subunit 2 -1.78873
ARHGAP11A Rho GTPase activating protein 11A -1.78657
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D -1.78391
CKAP2 cytoskeleton associated protein 2 -1.7803
CUBN cubilin (intrinsic factor-cobalamin receptor) -1.77635
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -1.77461
FMOD fibromodulin -1.77301
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1 -1.77123
STK4 serine/threonine kinase 4 -1.76447
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -1.76391
APOO apolipoprotein O -1.76254
STAT5A signal transducer and activator of transcription 5A -1.75611
GLA galactosidase, alpha -1.75417
CYCS cytochrome c, somatic -1.7496
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -1.74399
KLK2 kallikrein-related peptidase 2 -1.73237
SGPP1 sphingosine-1-phosphate phosphatase 1 -1.72561
RP2 retinitis pigmentosa 2 (X-linked recessive) -1.72473
SCML2 sex comb on midleg-like 2 (Drosophila) -1.70878
GFPT2 glutamine-fructose-6-phosphate transaminase 2 -1.70386
NHLH1 nescient helix loop helix 1 -1.69728
PWWP2A PWWP domain containing 2A -1.69687
POMT2 protein-O-mannosyltransferase 2 -1.69538
HOXB9 homeobox B9 -1.67231
VDAC1 voltage-dependent anion channel 1 -1.67117
STAT5B signal transducer and activator of transcription 5B -1.66812
NEFL neurofilament, light polypeptide -1.66669
CKAP5 cytoskeleton associated protein 5 -1.66153
RUSC2 RUN and SH3 domain containing 2 -1.66119
SPC25 SPC25, NDC80 kinetochore complex component -1.66102
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 -1.66039
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 -1.65547
FOXD1 forkhead box D1 -1.64984
COL8A1 collagen, type VIII, alpha 1 -1.64611
CLEC16A C-type lectin domain family 16, member A -1.63859
MRPL34 mitochondrial ribosomal protein L34 -1.60741
APOH apolipoprotein H (beta-2-glycoprotein I) -1.60375
ATPIF1 ATPase inhibitory factor 1 -1.60118
CACNB2 calcium channel, voltage-dependent, beta 2 subunit -1.59657
FKBP1B FK506 binding protein 1B, 12.6 kDa -1.5961
SYNGR3 synaptogyrin 3 -1.59418
MDH1 malate dehydrogenase 1, NAD (soluble) -1.58628
RNF114 ring finger protein 114 -1.5851
COL9A2 collagen, type IX, alpha 2 -1.58506
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B -1.58086
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 -1.57838
PER3 period circadian clock 3 -1.5759
ZMIZ1 zinc finger, MIZ-type containing 1 -1.57412
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 -1.56813
PLCH2 phospholipase C, eta 2 -1.56797
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae) -1.56783
NDUFA4 NDUFA4, mitochondrial complex associated -1.56319
HHEX hematopoietically expressed homeobox -1.55405
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 -1.55176
LHFP lipoma HMGIC fusion partner -1.55159
PLEK pleckstrin -1.55067
PHLDB1 pleckstrin homology-like domain, family B, member 1 -1.54941
DKFZP564C152 DKFZP564C152 protein -1.54716
IFNA7 interferon, alpha 7 -1.54645
NCBP1 nuclear cap binding protein subunit 1, 80kDa -1.5411
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa -1.53821
TMSB15A thymosin beta 15a -1.53419
DES desmin -1.53396
SLN sarcolipin -1.53369
ATP10B ATPase, class V, type 10B -1.53194
IDI1 isopentenyl-diphosphate delta isomerase 1 -1.53014
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae) -1.52857
VAV3 vav 3 guanine nucleotide exchange factor -1.51703
STC1 stanniocalcin 1 -1.51459
GAL3ST4 galactose-3-O-sulfotransferase 4 -1.51275
PRB4 proline-rich protein BstNI subfamily 4 -1.51067
AURKA aurora kinase A -1.50921
PHGDH phosphoglycerate dehydrogenase -1.50655
SARNP SAP domain containing ribonucleoprotein -1.5062
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) -1.5034
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1 -1.50216
PXMP2 peroxisomal membrane protein 2, 22kDa -1.50059
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 -1.49835
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C) -1.49616
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa -1.49514
CEP192 centrosomal protein 192kDa -1.49271
TTC17 tetratricopeptide repeat domain 17 -1.49152
ZBTB7A zinc finger and BTB domain containing 7A -1.489
CDK2 cyclin-dependent kinase 2 -1.48734
EXO1 exonuclease 1 -1.48272
UGT2A3 UDP glucuronosyltransferase 2 family, polypeptide A3 -1.48168
CPVL carboxypeptidase, vitellogenic-like -1.48022
CDC25C cell division cycle 25C -1.47705
CD300C CD300c molecule -1.47629
LIME1 Lck interacting transmembrane adaptor 1 -1.47425
CWF19L1 CWF19-like 1, cell cycle control (S. pombe) -1.4704
CPA4 carboxypeptidase A4 -1.47034
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 -1.47001
KDM4D lysine (K)-specific demethylase 4D -1.46078
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 -1.45747
IGFBP6 insulin-like growth factor binding protein 6 -1.45352
LMO2 LIM domain only 2 (rhombotin-like 1) -1.45241
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 -1.45069
UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa -1.44927
EIF1B eukaryotic translation initiation factor 1B -1.44492
CHPT1 choline phosphotransferase 1 -1.43945
BET1L Bet1 golgi vesicular membrane trafficking protein-like -1.43866
SEC13 SEC13 homolog (S. cerevisiae) -1.43571
TYMS thymidylate synthetase -1.43167
CNTRL centriolin -1.43093
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5 -1.42648
ADCY6 adenylate cyclase 6 -1.42379
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 -1.42359
H2AFV H2A histone family, member V -1.42305
AQP1 aquaporin 1 (Colton blood group) -1.41849
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 -1.4175